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BR-112020020812-B1 - Hard surface treatment compositions, their use, method for providing residual antimicrobial action and related substrate.

BR112020020812B1BR 112020020812 B1BR112020020812 B1BR 112020020812B1BR-112020020812-B1

Abstract

COMPOSITIONS AND METHODS FOR LONG-LASTING DISINFECTION An antimicrobial composition that includes: an antimicrobial component having at least one quaternary ammonium compound; a cationic polysaccharide; an organic acid; and a surfactant selected from cationic surfactants, amphoteric surfactants, nonionic surfactants and combinations thereof. This composition, when applied to a surface, provides robust long-lasting disinfection.

Inventors

  • Amit Sehgal
  • Thomas Brophy
  • Kamel Ramdani

Assignees

  • SPECIALTY OPERATIONS FRANCE

Dates

Publication Date
20260310
Application Date
20190409
Priority Date
20180409

Claims (14)

  1. 1. Hard surface treatment composition, characterized in that it comprises: a. an antimicrobial component comprising at least one quaternary ammonium compound; b. a cationic polysaccharide derived from a natural source, which is a cationic guar; c. an organic acid; d. a surfactant selected from the group consisting of cationic surfactants, amphoteric surfactants, nonionic surfactants and combinations thereof, wherein a film formed from the composition kills at least 95% of microorganisms during at least 3 abrasion cycles according to RSS-12h.
  2. 2. Composition according to claim 1, characterized in that the antimicrobial component is selected from the group consisting of monoalkyldimethylbenzyl ammonium salts, dialkyldimethyl ammonium salts and combinations thereof.
  3. 3. Composition according to claim 1, characterized in that the cationic guar is selected from the group consisting of guar hydroxypropyltrimonium chloride, hydroxypropyl guar hydroxypropyltrimonium chloride and combinations thereof.
  4. 4. Composition according to claim 1, characterized in that the organic acid is selected from the group consisting of citric, malic, maleic, lactic, succinic, glutaric, adipic acids and combinations thereof.
  5. 5. Composition according to claim 1, characterized in that the surfactant comprises a cationic surfactant selected from the group consisting of cationic amine oxides, cationic betaines, propionates, amphoacetates and combinations thereof.
  6. 6. Composition according to claim 1, characterized in that the surfactant comprises an amphoteric surfactant selected from the group consisting of sultaines, taurates and combinations thereof.
  7. 7. Composition according to claim 1, characterized in that it further comprises a polar solvent.
  8. 8. Composition, according to claim 1, characterized in that a film formed from the composition kills at least 95% of Gram-positive bacteria and Gram-negative bacteria or enveloped and non-enveloped viruses, according to Protocol #01-1A of the Environmental Protection Agency (EPA) Residual Self-Sanitizing Activity Test.
  9. 9. Composition according to claim 1, characterized in that it comprises: a. an antimicrobial component comprising at least one quaternary ammonium compound in an amount ranging from 800 ppm to 40,000 ppm; b. a cationic polysaccharide derived from a natural source, which is a cationic guar, in an amount ranging from 800 ppm to 30,000 ppm; c. an organic acid in an amount ranging from 1,000 ppm to 35,000 ppm; and d. a surfactant selected from the group consisting of cationic surfactants, amphoteric surfactants, nonionic surfactants and combinations thereof in an amount ranging from 2,000 ppm to 90,000 ppm.
  10. 10. Method for providing a surface with residual antimicrobial action, characterized in that it comprises the step of applying the composition, as defined in claim 1, to the surface, where therapeutic treatments of a human or animal body are excluded.
  11. 11. Substrate with residual antimicrobial action, characterized in that it comprises a substrate in which at least a portion of the substrate is coated with the composition as defined in claim 1.
  12. 12. Use of a composition, as defined in claim 1, characterized in that it is for substantially reducing or controlling the formation of microbial colonies on or in a surface, where therapeutic treatments of a human or animal body are excluded.
  13. 13. Use according to claim 12, characterized in that a film formed from the composition kills at least 95% of Gram-positive bacteria and Gram-negative bacteria or enveloped and non-enveloped viruses, according to a modified version of the Environmental Protection Agency (EPA) Residual Self-Sanitizing Activity Test Protocol #01-1A.
  14. 14. Use according to claim 12, characterized in that a film formed from the composition kills at least 95% of Gram-positive bacteria and Gram-negative bacteria or viruses with and without envelopes, according to Protocol #01-1A of the Environmental Protection Agency (EPA) Residual Self-Sanitizing Activity Test.

Description

CROSS-REFERENCE WITH RELATED REQUEST [0001] This application claims the benefit of priority under 35 U.S.C. §119(e) of U.S. Provisional Application Serial No. 62/654, 652, filed April 9, 2018, the entire disclosure of which is incorporated herein by reference. BACKGROUND [0002] It is often desirable to provide a biocidal surface on which microorganisms, many of which are potentially harmful, cannot survive, at least for a certain period of time. Most materials have surfaces that do not normally prevent microbial contamination. A useful way to improve the microbial resistance of a surface is to treat the surface with a formulation that provides a biocidal effect and also prevents future growth until the next application. [0003] A common method of treating a surface is to apply a layer of a liquid formulation to that surface and then dry the layer or allow the layer to dry. It is desirable that such liquid formulations be clear and remain stable during storage. It is also desirable that such liquid formulations spread evenly when applied to a flat, hard surface. It is desirable that such films, when dry, have one or more of the following desirable properties: clarity, non-stickiness; durability to touch or repeated rubbing; no long-term buildup; and ability to maintain biocidal efficacy under normal use for an extended period of time after application to a surface. [0004] Commercially available antimicrobial compositions, such as disinfectants or cleaning products with disinfectant activity, typically achieve microbial kill rates of 99.9% or higher. However, resoiling or surface contamination requires additional treatments with such compositions. Therefore, there is a need for antimicrobial formulations that provide high microbial kill rates without the need for repeated applications. However, designing compositions that meet the above requirements is a difficult task given the unpredictable and complex interactions between ingredients. BRIEF DESCRIPTION OF THE DRAWINGS [0005] FIG. 1 is the flowchart illustrating the RSS-12h analysis conducted in the Examples. SUMMARY [0006] This disclosure provides hard surface treatment compositions comprising: an antimicrobial component comprising at least one quaternary ammonium compound; a cationic polysaccharide derived from a natural source; an organic acid; and a surfactant selected from cationic surfactants, amphoteric surfactants, nonionic surfactants and combinations thereof. Methods of providing a surface with residual antimicrobial action are also presented, including the step of applying a composition of this disclosure to the surface. This disclosure also provides a substrate with residual antimicrobial action comprising a substrate in which at least a portion of the substrate is coated with a composition of this disclosure. DETAILED DESCRIPTION [0007] This disclosure relates to compositions that provide longer-lasting disinfection of treated surfaces and include cationic polysaccharides derived from a natural source. These compositions achieve at least 95% or more (e.g., 99.9% kill) of microorganisms (e.g., bacterial, viral, or fungal) within 12 to 24 hours, eliminating the need for repeated treatment. Suitable techniques for evaluating the effectiveness of the compositions in this disclosure include standard U.S. and European methods. [0008] In order to substantiate claims of long-term 24-hour sanitization with the United States Environmental Protection Agency (EPA), the compositions are evaluated using the Residual Self-Sanitization (RSS) method, EPA Protocol #01-1A (https://www.epa.gov/sites/production/files/2015-09/documents/cloroxpcolfinal.pdf). For validation of longer-term disinfection, all existing test protocols emulate the maximum amount of recontamination and abrasion from touch and cleaning anticipated before reapplication, typically a 24-hour period. An intermediate protocol with approximately half the level of abrasion and resoiling challenge to a surface is presented here as the “RSS-12h” test protocol. [0009] To meet the need for a European Standard Test Method by which residual antimicrobial activity can be measured and evaluated, the British Standards Institute recently published BSI-PAS-2424 entitled: “Quantitative surface test for the evaluation of the residual antimicrobial (bactericidal and/or yeasticidal) efficacy of liquid chemical disinfectants on hard non-porous surfaces - Test method”. Most methods involving antimicrobial efficacy testing involve applying a product to a surface and leaving it for a period of time before challenging it with microorganisms. The limitation of such methods is that the surface remains undisturbed after application. In fact, a Lancaster University report: “Cleaning Behaviors in the Home”, based on consumer research, showed that in domestic or work environments, as soon as a product has been applied to a surface, the surface is continuously exposed to abrasion such as touching and rubbing. This results in r