BR-112021015158-B1 - PESTICIDE COMPOSITIONS AND METHODS

BR112021015158B1BR 112021015158 B1BR112021015158 B1BR 112021015158B1BR-112021015158-B1

Abstract

The present invention relates to the field of molecules that have pesticidal utility against pests of the phyla Nematoda, Arthropoda and/or Mollusca, processes for producing such molecules and intermediates used in such processes, compositions containing such molecules and processes for using such molecules against such pests. These molecules can be used, for example, as nematicides, acaricides, insecticides, miticides and/or molluscicides. This document discloses molecules that have the structure of Formula A. Ar1 L1 Ar2 L2 R1 R4 N N N R3 Q1 Q2 R2

Inventors

NATALIE C. GIAMPIETRO
THOMAS J. BARTON
Gary Crouse
DAVID A. DEMETER
LINDSEY G. HORTY
THOMAS C. SPARKS
Andrew Ward

Assignees

CORTEVA AGRISCIENCE LLC

Dates

Publication Date: 20260310
Application Date: 20200130
Priority Date: 20190204

Claims (6)

1. A molecule characterized by having the structure of Formula One or Formula Two: wherein: (A) Ar1 is a phenyl or substituted phenyl having one or more substituents independently selected from C1-C6 haloalkyl and C1-C6 haloalkoxy; (B) Ar2 is phenyl; (C) R1 is H; (D) R2 and R3 are a saturated or unsaturated hydrocarbyl bond of 1 to 4 members and, together with (Q2)(C)(N), form a cyclic structure of 4 to 7 members, wherein said hydrocarbyl bond may be optionally substituted with one or more substituents independently selected from H, OH, and oxo; (E) R4 is phenyl, wherein the phenyl may be optionally substituted with one or more substituents independently selected from H, F, Cl, C1-C8 alkyl, C1-C8 alkoxy or C1-C8 haloalkoxy, or wherein two adjacent substituents form a saturated or unsaturated hydrocarbyl bond of 5 or 6 members; (F) L1 is a ligand selected from the group consisting of: wherein R5 is H;(G) each of R6, R7, R8 and R9 is selected from H or C1-C6 alkyl;(H) Q1 is selected from O or S; and(I) Q2 is selected from O or S.
2. Molecule, according to claim 1, characterized in that Ar1 is one that has one or more substituents selected independently from OCF3, OCF2CF3 and CF3.
3. Molecule according to claim 1, characterized in that L1 is selected from the group consisting of:
4. Molecule according to claim 1, characterized in that it has a structure selected from the following compounds.
5. Process for applying a molecule, as defined in claim 1, characterized in that it comprises applying a molecule, as defined in claim 1, to an area to control a pest, in an amount sufficient to control such pest, wherein said area is not the body of an animal, excluding methods of treatment or application to the human or animal body.
6. Use of a molecule, as defined in claim 1, characterized in that it is for preparing a product to be applied to an area to control a pest in a quantity sufficient to control such pest, excluding application to the human or animal body.

Description

CROSS-REFERENCE TO RELATED REQUESTS [0001] This application claims the benefit of Provisional Patent Application U.S. Serial Number 62/800587, filed February 4, 2019, which is expressly incorporated by reference herein. FIELD OF THE INVENTION [0002] The invention disclosed in this document relates to the field of pesticides and their use in pest control. BACKGROUND OF THE INVENTION [0003] Pests cause millions of human deaths worldwide annually. Furthermore, there are over ten thousand species of pests that cause agricultural losses. These agricultural losses amount to billions of US dollars annually. Termites cause damage to various structures, such as homes. These termite damage losses amount to billions of US dollars annually. As a final observation, many stored food pests eat and spoil stored food. These stored food losses amount to billions of US dollars annually, but more importantly, they deprive people of necessary food. [0004] There is an acute need for new pesticides. Insects are developing resistance to pesticides currently in use. Hundreds of insect species are resistant to one or more pesticides. The development of resistance to some of the older pesticides, such as DDT, carbamates, and organophosphates, is well known. But resistance has developed even to some of the newer pesticides. Therefore, there is a need for new pesticides and particularly for pesticides that have new modes of action. SUMMARY OF THE INVENTION [0005] In one aspect, molecules are provided that have the structure of formula A: wherein:(A) Ar1 is selected from (1) furanyl, phenyl, pyridazinyl, pyridyl, pyrimidinyl, tienyl, or (2) substituted furanyl, substituted phenyl, substituted pyridazinyl, substituted pyridyl, substituted pyrimidinyl or substituted tienyl, wherein said substituted furanyl, substituted phenyl, substituted pyridazinyl, substituted pyridyl, substituted pyrimidinyl and substituted tienyl has one or more substituents selected independently from H, F, Cl, Br, I, CN, OH, SH, NO2, oxo, thioxo, NRxRy, C1-C8 alkyl, C1-C8 haloalkyl, C3-C8 cycloalkyl, C3-C8 halocycloalkyl, C3-C8 cycloalkoxy, C3-C8 halocycloalkoxy, C1-C8 alkoxy, C1-C8 haloalkoxy, C2-C8 alkenyl, C3-C8 cycloalkenyl, C2-C8 haloalkenyl, C2-C8 alkynyl, S(=O)n(C3-C8 cycloalkyl), S(=O)n(C3-C8 halocycloalkyl), S(=O)n(C1-C8 alkyl), S(=O)n(C1-C8 haloalkyl), OSO2(C1-C8 alkyl), OSO2(C1-C8 haloalkyl), C(=O)NRxRy, (C1-C8 alkyl)NRxRy, C(=O)C(=O)(C1- C8 alkyl), C(=O)O(C1-C8 alkyl), C(=O)(C1-C8 haloalkyl), C(=O)O(C1-C8 haloalkyl), C(=O)(C3-C8 cycloalkyl), C(=O)O(C3-C8 cycloalkyl), C(=O)(C2-C8 alkenyl),C(=O)O(C2-C8 alkenyl), (C1-C8 alkyl)O(C1-C8 alkyl), (C1C8 alkyl)S(=O)n(C1-C8 alkyl), (C1-C8 alkyl)OC(=O)(C1-C8 alkyl), (C1-C8 alkyl)OC(=O)O(C1-C8 alkyl), C(=O)(C1-C8 alkyl)C(=O)O(C1-C8 alkyl), (C1-C8 alkyl)C(=O)O(C1-C8 alkyl), (C1-C8 alkyl)C(=O)(C1-C8 alkyl), (C1-C8alkyl)phenyl, (C1-C8 alkyl)-O-phenyl, phenyl, phenoxy, Si(C1-C8 alkyl)3, or S(=O)nNRxRy or (Het-1), wherein each substituent of alkyl, haloalkyl, cycloalkyl, halocycloalkyl, alkoxy, haloalkoxy, alkenyl, cycloalkenyl, haloalkenyl, alkynyl, phenyl, phenoxy and (Het-1) may be optionally substituted with one or more substituents independently selected from H, F, Cl, Br, I, CN, OH, SH, NO2, oxo, thioxo, NRxRy, C1-C8 alkyl, C1-C8 haloalkyl, C3-C8 cycloalkyl, C3-C8 halocycloalkyl, C3-C8 cycloalkoxy, C3-C8 halocycloalkoxy, C1-C8 alkoxy, C1-C8 haloalkoxy, C2-C8 alkenyl, C3-C8 cycloalkenyl, C2-C8 haloalkenyl, C2-C8 alkynyl, S(=O)n(C3-C8 cycloalkyl), S(=O)n(C3-C8 halocycloalkyl), S(=O)n(C1-C8 alkyl), S(=O)n(C1-C8 haloalkyl), OSO2(C1-C8 alkyl), OSO2(C1-C8 haloalkyl), C(=O)NRxRy, (C1-C8 alkyl)NRxRy, C(=O)(C1-C8 alkyl), C(=O)O(C1-C8 alkyl), C(=O)(C1-C8 haloalkyl), C(=O)O(C1-C8 haloalkyl), C(=O)(C3-C8 cycloalkyl), C(=O)O(C3-C8 cycloalkyl), C(=O)(C2-C8 alkenyl), C(=O)O(C2-C8 alkenyl), (C1-C8 alkyl)O(C1-C8 alkyl), (C1-C8 alkyl)S(=O)n(C1-C8 alkyl), (C1-C8 alkyl)OC(=O)(C1-C8 alkyl), (C1-C8 alkyl)OC(=O)O(C1-C8 alkyl), C(=O) (C1-C8 alkyl) alkyl)3, S(=O)nNRxRy or (Het-1);(B) Ar2 is selected from (1) furanyl, phenyl, pyridazinyl, pyridyl, pyrimidinyl, tienyl, or (2) substituted furanyl, substituted phenyl, substituted pyridazinyl, substituted pyridyl, substituted pyrimidinyl or substituted tienyl, wherein said substituted furanyl, substituted phenyl, substituted pyridazinyl, substituted pyridyl, substituted pyrimidinyl and substituted tienyl have one or more substituents selected independently from H, F, Cl, Br, I, CN, OH, SH, NO2, oxo, thioxo, NRxRy, C1-C8 alkyl, C1-C8 haloalkyl, C3-C8 cycloalkyl, C3-C8 halocycloalkyl, C3-C8 cycloalkoxy, C3-C8 halocycloalkoxy, C1-C8 alkoxy, C1-C8 haloalkoxy, C2-C8 alkenyl, C3-C8 cycloalkenyl, C2-C8 haloalkenyl, C2-C8 alkynyl, S(=O)n(C3-C8 cycloalkyl), S(=O)n(C3-C8 halocycloalkyl), S(=O)n(C1-C8 alkyl), S(=O)n(C1-C8 haloalkyl), OSO2(C1-C8 alkyl), OSO2(C1-C8 haloalkyl), C(=O)NRxRy, (C1-C8 alkyl)NRxRy, C(=O)(C1-C8alkyl), C(=O)O(C1-C8 alkyl), C(=O)(C1-C8 haloalkyl), C(=O)O(C1-C8 haloalkyl), C(=O)(C3-C