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CA-3154135-C - DRUG DELIVERY SYSTEM WITH STACKABLE SUBSTRATES

CA3154135CCA 3154135 CCA3154135 CCA 3154135CCA-3154135-C

Abstract

The present invention is directed to an electrically conductive substrate (1002) coated with one or more herbal essences wherein the substrate may be a flat sheet of conductive metal or polymer. The coating (1120) may be present as separate sections on the substrate and multiple conductor contacts may be present on the substrate or may be separate components. Multiple coated substrates may be stacked together to form a cartridge for use in an herbal essence delivery device.

Inventors

  • Timothy McCullough

Assignees

  • VAPOR CARTRIDGE TECHNOLOGY LLC

Dates

Publication Date
20260505
Application Date
20200709
Priority Date
20190916

Claims (20)

  1. CLAIMS 1. A coated substrate comprising: a flat, electrically conductive sheet comprising two sides, side edges, and front and back edges and comprising on one of the sides a coating of one or more herbal essences, wherein the coating of one or more herbal essences is separated into sections with spaces free of the herbal essences between the sections, each of the sections having a length corresponding to a dimension of the sheet from the front to the back edges and a width corresponding to a portion of a dimension of the sheet from one of the side edges to an opposing one of the side edges, the sum of the widths of the sections and the spaces between the coating sections being the dimension of the sheet from one of the side edges to an opposing one of the side edges; and multiple mesh structures positioned either on the side opposite the coating side or on the coating side, wherein each of the mesh structures has a length corresponding to the dimension of the sheet from the front to the back edges and a width corresponding to the width of the coating sections so as to provide spaces between the mesh structures corresponding to the spaces between the coating sections.
  2. 2. A coated substrate according to claim 1 or 2 wherein the conductive sheet further comprises multiple conductors positioned on the side with the coating or the side without the coating.
  3. 3. A coated substrate according to claim 2 wherein the multiple conductors are positioned either at the spaces on the section coating side of the sheet or positioned on the side of the sheet opposite the section coating side and at locations corresponding to the spaces.
  4. 4. A coated substrate according to claim 3 wherein the conductors are positioned on the side of the sheet opposite the coating section side.
  5. 5. A coated substrate according to any one of claims 1-4 wherein the multiple mesh structures are positioned on the same side as the section coating side and the mesh structures are coated by the one or more herbal essences. 31
  6. 6. A cartridge comprising a stack of multiple members of the coated substrate of any one of claims 3-4 wherein the conductors of the members are positioned on the side opposite the coating and the conductors of one member fit into the spaces between the sections of coating or the mesh structures/the coating of an adjacent member of the stack.
  7. 7. A single article comprising the coated substrate according to claim 1.
  8. 8. A coated substrate with frame comprising a single article according to claim 7 in combination with a non-conductive holding frame with bars wherein the bars of the frame mate with the spaces of the coated substrate thereby providing the coated substrate with frame.
  9. 9. A package of multiple numbers of the coated substrate with frame according to claim 8.
  10. 10. A grid-substrate combination comprising the single article according to claim 7 in combination with a grid comprising a non-conductive plate with conductive rails wherein the rails of the grid mate with the spaces of the coated substrate, the plate of the grid having a length and width the same as the length and width of the flat electrically conductive sheet of the coated substrate.
  11. 11. A cartridge comprising a stack comprising stacked members of the grid-substrate combination of claim 10 wherein the stack has a length and width defined by a length and a width of the grid-substrate combination and a height defined by the stack, and the cartridge further comprises solid support structures attached to sides of the grid plate defined by edges of the plate and adjacent members of the stack define slots containing the single article such that the single article may be removed from the cartridge and replaced by new single articles.
  12. 12. The coated substrate of any one of claims 1-5, the cartridge of any one of claims 6 or 11, the single article of claim 7, the coated substrate of claim 8, the package of multiple numbers of the coated substrate of claim 9, or the grid-substrate combination of claim 10, wherein the one or more herbal essences comprise at least one of CBD and THC. 32
  13. 13. The coated substrate of any one of claims 1-5, the cartridge of any one of claims 6 or 11, the single article of claim 7, the coated substrate of claim 8, the package of multiple numbers of the coated substrate of claim 9, or the grid-substrate combination of claim 10, wherein the one or more herbal essences comprise herbal extracts of one or more herbaceous plants.
  14. 14. A method for production of the cartridge according to claim 6 comprising providing the electrically conductive sheet with the multiple conductors and the multiple mesh structures; depositing the one or more herbal essences onto the sheet with the multiple mesh structures so as to form the sections of the coatings on the sheet side opposite the mesh structures or on the mesh structures to form the coated substrate; and stacking the multiple coated substrates to form the cartridge.
  15. 15. A method for production of the cartridge of claim 11 comprising: providing the electrically conductive sheet; depositing the one or more herbal essences onto the sheet to form the coated substrate; combining the coated substrate with the grid to form the grid-substrate combination; and stacking a plurality of the grid-substrate combinations and joining the solid support structures to the sides of the plates to form the cartridge.
  16. 16. A method according to claim 14 wherein the conductors are integrally formed on the electrically conductive sheet.
  17. 17. A method according to claim 14 wherein the conductors are separately formed and are attached to the electrically conductive sheet prior to the depositing of the one or more herbal essences onto the sheet.
  18. 18. A method for production of the package according to claim 9 comprising: providing the electrically conductive sheet; depositing the one or more herbal essences onto the conductive sheet as the separate coating sections thereby producing the coated substrate; 33 combining the coated substrate and the non-conductive holding frame to form the coated substrate with frame; and stacking a plurality of the coated sheets with frames to provide the package.
  19. 19. A package according to claim 18 wherein the coated substrate is configured for removal from the holding frame and insertion into the cartridge of claim 11.
  20. 20. A method for production of the coated substrate of claim 1 comprising combining a template and the conductive sheet so as to provide masked and unmasked areas of the sheet that will become the spaces between the sections of the herbal essence coatings and become the sections of the herbal essence coatings respectively and depositing the one or more herbal essences onto the non-masked areas of the conductive sheet to provide the coated substrate.

Description

DRUG DELIVERY SYSTEM WITH STACKABLE SUBSTRATES BACKGROUND 5 [0001] The Thermal Distillation and Wet Extraction Processes described in earlier applications and patents, including for example, U.S. Patent No's. 9,220,294 and 10,661,036 provide processes for preparation of herbal essence cartridges for use in vapor inhalation delivery systems. These processes enable regulated condensation or deposit of the herbal essence onto a conductive substrate which can be electronically managed to provide 10 controlled re-volatilization of the herbal essence. This process is pictorially represented by Fig 1. Fig. I shows a single sheet, single side coating process using heat to selective volatiles only the herbal essences such as cannabinoids that then condenses them onto a chilled substrate. These processes enable controlled, precisely metered delivery to the user or patient of appropriate dosages of herbal essences such as but not limited to cannabinoids, beneficial 15 remedies such as menthol, camphor, echinacea extract as well as other herbal treatments. [0002] The method for converting the coated substrate into a Vapor Cartridge is described in earlier applications and patents by Applicant, including for example, U.S. Patent No. 9,408,986. The Vapor Cartridge can be constructed from an extruded aluminum substrate. Liquid aluminum can be extruded to create a conductive substrate which consists of multiple 20 parallel electrical circuits defined by parallel, low resistance, conductors on either side of a high resistance heating elements as shown in Fig's. 2A and 2B. When a current is driven through one of the parallel conductors through the high resistance heating element section returning to the other parallel conductor, that element heats up and volatizes the coating of cannabinoids previously deposited. 25 [0003] In one example, as shown in Fig. 3, the coated substrate can be converted by rolling the coated substrate to form a cylindrical structure having a spiral cross-section, when viewed from a longitudinal end of the rolled sheet. [0004] The process of converting the flat extruded aluminum substrate, coated with its high concentration of herbal essences including but not limited to cannabinoids, and into a Vapor 30 Cartridge can include rolling the substrate up into a spiral with the multiple parallel conductors outwardly exposed. Non-conductive spacers can create an open airflow tunnel through the Vapor Cartridge. 1 Date Re9ue/Date Received 2023-08-31 [0005] The spiral construction of the Vapor Cartridge as shown in Fig 5 lends itself well to a continuous roll coating processing. [0006] Figure 7 depicts a physical Drug Delivery Device designed to implement the concepts described in Figure 6. An important function of the drug delivery device is cleanly and 5 efficiently extracting the herbal essences through use of a volatilizing chamber. [0007] Figure 8 shows a functional block diagram depicting how the exposed parallel conductors of the Vapor Cartridge match up to the contacts in the volatizing chamber. When, directed by the patient, a well-controlled current is driven through the selected section, volatizing the coating of herbal essences such as but not limited to cannabinoids. SUMMARY [0008] The present invention is directed to an alternative Vapor Cartridge utilizing an electrically conductible substrate coated with at least one or more herbal essences which is configured so as to manageably convert the one or more herbal essences into a vapor for inhalation into the lungs. An embodiment of the alternative Vapor Cartridge comprises a 15 substrate of an electrically conductible material with conductor contacts and having coated on one side at least one herbal essence. The at least one herbal essence is coated on the substrate and includes such volatilizable essences as cannabinoids, hops, echinacea extracts, terpenoid extracts such as peppermint, spearmint, menthol, and similar volatilizable plant oils, gums, solids and similar essences. The electrically conductible substrate may be an electrically 20 conductible metal or polymer having at least two low resistance conductor contacts positioned at opposite ends of, and conductively attached to, the substrate. [0009] In preferred embodiments, in one alternative, the substrate is a flat sheet and in another alternative is a flat sheet configured with a mesh. The herbal essence is coated onto one surface of the flat sheet or is coated onto the mesh. When the mesh is configured with 25 the substrate to become coated with herbal essence, the mesh is electrically conductive so that the herbal essence coated thereon can be volatilized. In an alternative configuration, the side of the sheet opposite side onto which the herbal essence is to be coated may be configured with an open mesh. The herbal essence is configured in this alternative configuration as a linear continuous layer on the surface of the sheet. The open mesh configuration of this 30 alternative config