Search

CA-3295216-A1 - FUNGICIDAL COMBINATIONS, MIXTURES AND COMPOSITIONS AND USES THEREOF

CA3295216A1CA 3295216 A1CA3295216 A1CA 3295216A1CA-3295216-A1

Inventors

  • Sami SHABTAI

Assignees

  • ADAMA MAKHTESHIM LTD.

Dates

Publication Date
20260302
Application Date
20200721
Priority Date
20190722

Claims (1)

  1. <pat:ClaimStatement>CLAIMS:</pat:ClaimStatement> <pat:Claims com:id="claims"> <pat:Claim com:id="CLM-00001"> <pat:ClaimNumber>1</pat:ClaimNumber> <pat:ClaimText>1. A fungicidal combination comprising: (i) an amount of a compound of Formula I [Image disponible dans le document PDF, Image available in the PDF document] Formula I , and (ii) an amount of at least one fungicide (A) selected from the group consisting of fenpicoxamid, pydiflumetofen and mefentrifluconazole. </pat:ClaimText> </pat:Claim> <pat:Claim com:id="CLM-00002"> <pat:ClaimNumber>2</pat:ClaimNumber> <pat:ClaimText>2. The combination of claim 1, wherein: a) the combination is more effective in treating a plant or locus against fungal infection than when each fungicide at the same amount is applied alone, b) the amount of the compound of Formula I and the amount of the fungicide (A) when applied together is more effective in treating a plant or locus against fungal infection than when each fungicide at the same amount is applied alone, and/or c) the amount of the compound of Formula I applied is less than the fungicidally effective amount of the compound of Formula I when the compound of Formula I is used alone, and/or wherein the amount of the fungicide (A) applied is less than the fungicidally effective amount of the fungicide (A) when the fungicide (A) is used alone. </pat:ClaimText> </pat:Claim> <pat:Claim com:id="CLM-00003"> <pat:ClaimNumber>3</pat:ClaimNumber> <pat:ClaimText>3. The combination of claim 1 or 2, wherein weight ratio of the compound of Formula I to fungicide (A) is from about 400:1 to 1:400. </pat:ClaimText> </pat:Claim> <pat:Claim com:id="CLM-00004"> <pat:ClaimNumber>4</pat:ClaimNumber> <pat:ClaimText>4. The combination of any one of claims 1-3 further comprising at least one pesticide, at least one stabilizing surfactant, and/or at least one phytologically acceptable adjuvant. </pat:ClaimText> </pat:Claim> <pat:Claim com:id="CLM-00005"> <pat:ClaimNumber>5</pat:ClaimNumber> <pat:ClaimText>5. A mixture comprising the combination of any one of claims 1-4. </pat:ClaimText> </pat:Claim> <pat:Claim com:id="CLM-00006"> <pat:ClaimNumber>6</pat:ClaimNumber> <pat:ClaimText>6. The mixture of claim 5, wherein the mixture is a tank mix. </pat:ClaimText> </pat:Claim> <pat:Claim com:id="CLM-00007"> <pat:ClaimNumber>7</pat:ClaimNumber> <pat:ClaimText>7. A composition comprising the combination of any one of claims 1-4. </pat:ClaimText> </pat:Claim> <pat:Claim com:id="CLM-00008"> <pat:ClaimNumber>8</pat:ClaimNumber> <pat:ClaimText>8. The composition of claim 7, wherein: a) the composition comprises the compound of Formula I in an amount ranging from about 0.1% to 90% by weight based on the total weight of the composition, and/or b) the composition comprises fungicide (A) in an amount ranging from about </pat:ClaimText> </pat:Claim> <pat:Claim com:id="CLM-00009"> <pat:ClaimNumber>9</pat:ClaimNumber> <pat:ClaimText>9. The composition of claim 7 or 8, wherein the composition further comprises a phytologically acceptable carrier. </pat:ClaimText> </pat:Claim> <pat:Claim com:id="CLM-00010"> <pat:ClaimNumber>10</pat:ClaimNumber> <pat:ClaimText>10. A method for: a) treating a plant or locus against fungal infection comprising applying (i) an amount of a compound of Formula I [Image disponible dans le document PDF, Image available in the PDF document] Formula I , and (ii) an amount of at least one fungicide (A) selected from the group consisting of fenpicoxamid, pydiflumetofen and mefentrifluconazole, to the plant or locus, so as to thereby treat the plant or locus against fungal infection, or b) treating a plant or locus against fungal infection comprising applying an effective amount of the combination of any one of claims 1-4, mixture of claim 5 or 6, or composition of any one of claims 7-9 to the plant or locus so as to thereby treat the plant or locus against fungal infection. </pat:ClaimText> </pat:Claim> <pat:Claim com:id="CLM-00011"> <pat:ClaimNumber>11</pat:ClaimNumber> <pat:ClaimText>11. The method of claim 10, wherein: a) the method is more effective in treating a plant or locus against fungal infection than when each fungicide at the same amount is applied alone, b) the amount of the compound of Formula I and the amount of the fungicide (A) when applied together is more effective in treating a plant or locus against fungal infection than when each fungicide at the same amount is applied alone, c) the amount of the compound of Formula I applied is less than the fungicidally effective amount of the compound of Formula I when the compound of Formula I is used alone and/or the amount of the fungicide (A) applied is less than the fungicidally effective amount of the fungicide (A) when the fungicide (A) is used alone, d) the method is effective for controlling fungal infection of the plant or locus, and/or e) the method is effective for protecting the plant or locus against fungal infection. </pat:ClaimText> </pat:Claim> <pat:Claim com:id="CLM-00012"> <pat:ClaimNumber>12</pat:ClaimNumber> <pat:ClaimText>12. The method of claim 11, wherein: a) controlling fungal infection comprises controlling fungal disease infecting the plant or locus, controlling a plant or soil disease caused by phytopathologic fungi, controlling fungal attack on the plant or locus, reducing fungal infection of the plant or locus, and/or curing a plant or soil disease caused by phytopathologic fungi, and/or b) protecting the plant or locus against fungal infection comprises protecting the plant or locus against fungal attack, protecting the plant or locus from fungal disease, and/or preventing fungal infection of the plant or locus. </pat:ClaimText> </pat:Claim> <pat:Claim com:id="CLM-00013"> <pat:ClaimNumber>13</pat:ClaimNumber> <pat:ClaimText>13. The method of any one of claims 10-12, wherein: a) the compound of Formula I and the fungicide (A) are applied to propagation material of the plant, b) the compound of Formula I and the fungicide (A) are applied to seed and/or seedling of the plant, c) the method comprises a protectant application of the compound of Formula I and the fungicide (A), d) the method comprises a curative application of the compound of Formula I and the fungicide (A), e) the compound of Formula I and the fungicide (A) are applied simultaneously or contemporaneously, f) the compound of Formula I and the fungicide (A) are applied separately or together, g) the method is effective for reducing leaf necrosis, h) the compound of Formula I is applied at an amount from 1 g/ha to 500 g/ha, and/or i) the fungicide (A) is applied at an amount from 0.1 g/ha to 500 g/ha. </pat:ClaimText> </pat:Claim> <pat:Claim com:id="CLM-00014"> <pat:ClaimNumber>14</pat:ClaimNumber> <pat:ClaimText>14. The method of any one of claims 10-13, wherein the compound of Formula I is applied at an amount of 5 g/ha or 10 g/ha. </pat:ClaimText> </pat:Claim> <pat:Claim com:id="CLM-00015"> <pat:ClaimNumber>15</pat:ClaimNumber> <pat:ClaimText>15. The method of any one of claims 10-14, wherein: a) the pydiflumetofen is applied in the range of 0.0001 g/ha to 150g/ha, b) the mefentrifluconazole is applied in the range of 0.1 g/ha to 150 g/ha, or c) the fenpicoxamid is applied in the range of 0.1 g/ha to 150 g/ha. </pat:ClaimText> </pat:Claim> <pat:Claim com:id="CLM-00016"> <pat:ClaimNumber>16</pat:ClaimNumber> <pat:ClaimText>16. A method: a) for controlling a plant disease caused by phytopathologic fungi comprising contacting the plant or a locus of the plant with an effective amount the combination of any one of claims 1-4, mixture of claim 5 or 6, or composition of any one of claims 7-9 so as to thereby control the plant disease, b) for controlling fungal attack on a plant, seed or seedling comprising applying the combination of any one of claims 1-4, mixture of claim 5 or 6, or composition of any one of claims 7-9 to the plant, seed, seedling and/or a locus of the plant so as to thereby control fungal attack on the plant, seed or seedling, c) for controlling fungal attack on a plant, seed or seedling comprising applying the combination of any one of claims 1-4, mixture of claim 5 or 6, or composition of any one of claims 7-9 to the plant, seed, seedling and/or locus of the plant so as to thereby control fungal attack on the plant, seed or seedling, d) of treating a plant, seed or seedling to produce a plant resistant to fungal attack, the method comprising applying the combination of any one of claims 1-4, mixture of claim 5 or 6, or composition of any one of claims 7- 9 to the plant, seed adapted to produce the plant, seeding adapted to produce the plant, or a locus of the plant so as to thereby produce a plant resistant to fungal attack, or e) of protecting a plant from fungal attack, the method comprising applying the combination of any one of claims 1-4, mixture of claim 5 or 6, or composition of any one of claims 7-9 to the to the plant, a locus of the plant, or a seed or seedling adapted to produce the plant so as to thereby protect the plant from fungal attack. </pat:ClaimText> </pat:Claim> <pat:Claim com:id="CLM-00017"> <pat:ClaimNumber>17</pat:ClaimNumber> <pat:ClaimText>17. A plant resistant to fungal attack, wherein the seed adapted to produce the plant, the seedling adapted to produce the plant, or a locus of plant is treated with the combination of any one of claims 1-4, mixture of claim 5 or 6, or composition of any one of claims 7-9. </pat:ClaimText> </pat:Claim> <pat:Claim com:id="CLM-00018"> <pat:ClaimNumber>18</pat:ClaimNumber> <pat:ClaimText>18. A plant seed or seedling adapted to produce a plant resistant to fungal attack, wherein the plant seed or seedling is treated with the combination of any one of claims 1-4, mixture of claim 5 or 6, or composition of any one of claims 7-9. </pat:ClaimText> </pat:Claim> <pat:Claim com:id="CLM-00019"> <pat:ClaimNumber>19</pat:ClaimNumber> <pat:ClaimText>19. A method: a) for the controlling fungal attack on a plant comprising applying the combination of any one of claims 1-4, mixture of claim 5 or 6, or composition of any one of claims 7-9 to soil, plant, root, foliage, seed, locus of the fungus, and/or a locus in which the infestation is to be prevented so as to thereby control fungal attack on the plant, b) for the controlling plant and/or soil fungal diseases comprising applying the combination of any one of claims 1-4, mixture of claim 5 or 6, or composition of any one of claims 7-9 to soil, plant, root, foliage, seed, locus of the fungus, and/or a locus in which the infestation is to be prevented so as to thereby control plant and/or soil fungal diseases, c) for controlling plant disease caused by phytopathologic fungi comprising contacting the plant, propagation material of the plant, or a locus of the plant with (i) an amount of a compound of Formula I [Image disponible dans le document PDF, Image available in the PDF document] Formula I , and (ii) an amount of at least one fungicide (A) selected from the group consisting of fenpicoxamid, pydiflumetofen and mefentrifluconazole, so as to thereby control the plant disease, d) for controlling fungal attack on a plant, seed or seedling comprising applying to the plant, seed, seedling and/or a locus of the plant (i) an amount of a compound of Formula I [Image disponible dans le document PDF, Image available in the PDF document] Formula I , and (ii) an amount of at least one fungicide (A) selected from the group consisting of fenpicoxamid, pydiflumetofen and mefentrifluconazole, so as to thereby control fungal attack on the plant, seed or seedling, or e) for protecting a plant, seed or seedling from fungal attack comprising applying to the plant, seed, seedling and/or locus of the plant (i) an amount of a compound of Formula I [Image disponible dans le document PDF, Image available in the PDF document] Formula I , and (ii) an amount of at least one fungicide (A) selected from the group consisting of fenpicoxamid, pydiflumetofen and mefentrifluconazole, so as to thereby protect the plant, seed or seedling from fungal attack. </pat:ClaimText> </pat:Claim> <pat:Claim com:id="CLM-00020"> <pat:ClaimNumber>20</pat:ClaimNumber> <pat:ClaimText>20. Use of the combination of any one of claims 1-4, mixture of claim 5 or 6, or composition of any one of claims 7-9 for treating a plant or locus against fungal infection. </pat:ClaimText> </pat:Claim> <pat:Claim com:id="CLM-00021"> <pat:ClaimNumber>21</pat:ClaimNumber> <pat:ClaimText>21. The combination of any one of claims 1-4, mixture of claim 5 or 6, or composition of any one of claims 7-9 for use to treat a plant or locus against fungal infection. </pat:ClaimText> </pat:Claim> </pat:Claims>

Description

FUNGICIDAL COMBINATIONS, MIXTURES AND COMPOSITIONS AND USES THEREOF This application is a divisional of Canadian Patent application serial number 3,145,270 filed on July 21, 2020. This application claims benefit of U.S. Provisional Application No. 62/877,180, filed July 22, 2019. FIELD OF THE INVENTION This disclosure concerns combinations comprising (i) an amount of a compound of Formula I and (ii) an amount of at least one fungicide (A) selected from the group consisting of fluindapyr, pydiflumetofen, mefentrifluconazole, inpyrfluxam, isofetamid and Qi inhibitor. This disclosure also concerns compositions comprising the combinations described herein and methods of use of the combinations described herein. BACKGROUND AND SUMMARY Fungicides are compounds, of natural or synthetic origin, which act to protect plants against damage caused by fungi. Current methods of agriculture rely heavily on the use of fungicides. In fact, some crops cannot be grown usefully without the use of fungicides. Using fungicides allows a grower to increase the yield and the quality of the crop, and consequently, increase the value of the crop. In most situations, the increase in value of the crop is worth at least three times the cost of the use of the fungicide. 5-fluoro-4-imino-3-methyl-1-tosyl-3,4-dihydropyrimidin-2(1H)-one is a compound which provides control of a variety of pathogens affecting economically important crops including, but not limited to, the causal agent of leaf blotch in wheat, Zymoseptoria tritici (SEPTTR) and fungi of the classes ascomycetes and basidiomycetes. 5-fluoro-4-imino-3-methyl-1-tosyl-3,4-dihydropyrimidin-2(1H)-one has both preventive and curative effects. Uses of N3-substituted-N1-sulfonyl-5-fluoropyrimidinone derivatives as fungicides were described in U.S. Patent No. 8,263,603, issued September 11, 2012. Methods of preparation of 5-fluoro-4-imino-3-methyl-1-tosyl-3,4-dihydropyrimidin-2(1H)-one were described in U.S. Patent No. 9,850,215, issued December 26, 2017 and U.S. Patent No. 9,840,476, issued December 12, 2017. U.S. Patent No. 8,263,603 also described fungicidal compositions for the control or prevention of fungal attack comprising N3-substituted-N1-sulfonyl-5- fluoropyrimidinone derivatives and a phytologically acceptable carrier material, and methods of use thereof. Use of 5-fluoro-4-imino-3-(alkyl/substituted alkyl)-1-(arylsulfonyl)-3,4- dihydropyrimidin-2(1H)-one as seed treatment to prevent or control plant disease was described U.S. Patent Application Publication No. 2018/0000082, published on January 4, 2018. Synergistic mixtures comprising 5-fluoro-4-imino-3-methyl-1-tosyl-3,4- dihydropyrimidin-2(1H)-one and at least one fungicidal sterol biosynthesis inhibitor were described in U.S. Patent No. 9,526,245, issued December 27, 2016 and U.S. Patent No. 10,045,533, issued August 14, 2018. Synergistic mixtures comprising 5-fluoro-4-imino-3-methyl-1-tosyl-3,4- dihydropyrimidin-2(1H)-one and at least one succinate dehydrogenase inhibitor were described in U.S. Patent No. 9,532,570, issued January 3, 2017 and U.S. Patent No. 10,045,534, issued August 14, 2018. Many fungicides are not useful in all situations and repeated usage of a single fungicide frequently leads to the development of resistance to the related fungicides. Consequently, research is being conducted to produce fungicides and combinations of fungicides that are safer, that have better performance, that are effective over long periods of time, that require lower dosages, that are easier to use, and that cost less. It is an object of this disclosure to provide synergistic combinations, including mixtures, comprising the compound of Formula I and at least one additional fungicide. It is a further object of this disclosure to provide composition and uses of these synergistic combinations, including mixtures. SUMMARY OF THE INVENTION The present invention provides a fungicidal combination comprising: (i) an amount of a compound of Formula I [Image disponible dans le document PDF, Image available in the PDF document] Formula I , and (ii) an amount of at least one fungicide (A) selected from the group consisting of fluindapyr, pydiflumetofen, mefentrifluconazole, inpyrfluxam, isofetamid, and Qi inhibitor. The present invention also provides a mixture comprising the combinations described herein. The present invention also provides a composition comprising the combinations described herein. The present invention also provides a method for treating a plant or locus against fungal infection comprising applying (i) an amount of a compound of Formula I [Image disponible dans le document PDF, Image available in the PDF document] Formula I , and (ii) an amount of at least one fungicide (A) selected from the group consisting of fluindapyr, pydiflumetofen, mefentrifluconazole, inpyrfluxam, isofetamid and Qi inhibitor, so as to thereby treat the plant or locus against fungal infection. The present invention also provides a method for treati