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CN-114126494-B - System and method for measuring elasticity using imaging of multi-dimensional ultrasonic multifocal shear waves

CN114126494BCN 114126494 BCN114126494 BCN 114126494BCN-114126494-B

Abstract

Embodiments of a skin cosmetic treatment and/or imaging system and method adapted to alter the placement and location of multiple (e.g., two or more) cosmetic treatment zones in tissue from an ultrasound beam from a transducer, simultaneously multifocal treatment at multiple depths, and/or dither the ultrasound beam from the transducer to alter the placement and location of multiple cosmetic treatment zones in tissue. The system may include a hand wand, a removable transducer module, and a control module. In some embodiments, the cosmetic treatment system may be used in a variety of cosmetic procedures.

Inventors

  • C.D. Emory
  • XU DAOZHONG

Assignees

  • 奥赛拉公司
  • 奥赛拉公司

Dates

Publication Date
20260421
Application Date
20200713
Priority Date
20190715

Claims (20)

  1. 1. A system for measuring elasticity of a material, the system comprising: An ultrasound probe including an ultrasound transducer configured to deliver a plurality of ultrasound beams to a material, The material is provided with an elastic property such that, The plurality of ultrasound beams are focused at a plurality of individually spaced focal zones in the material, Each ultrasonic beam has sufficient acoustic power to generate shear waves originating from the individually spaced focal zones and traveling through the material; An ultrasound imaging system configured to image shear waves originating from at least two of the plurality of individually spaced apart focal regions and converging through an interrogation zone toward a region between the at least two of the plurality of individually spaced apart focal regions, and An electronic processing system configured to: obtaining characteristics of imaged shear waves, and The elasticity of the query region of the material is determined based on the obtained characteristics.
  2. 2. The system of claim 1, wherein the characteristics of the imaged shear wave include at least one of arrival time of the shear wave, peak displacement of the shear wave, rise time of the shear wave, and fall time of the shear wave.
  3. 3. The system of claim 1, wherein the ultrasound transducer is configured to deliver the ultrasound beam to the material using amplitude modulation to focus the ultrasound beam at the plurality of individually spaced focal zones in the material.
  4. 4. The system of claim 3, wherein the ultrasound beam is focused simultaneously at the plurality of individually spaced focal zones in the material.
  5. 5. The system of claim 3, wherein the ultrasound beam is sequentially focused at the plurality of individually spaced focal zones in the material.
  6. 6. The system of claim 1, wherein the ultrasound transducer is configured to deliver the ultrasound beam to the material using frequency modulation to focus the ultrasound beam at the plurality of individually spaced focal zones in the material.
  7. 7. The system of claim 6, wherein the ultrasound beam is focused simultaneously at the plurality of individually spaced focal zones in the material.
  8. 8. The system of claim 6, wherein the ultrasound beam is sequentially focused at the plurality of individually spaced focal zones in the material.
  9. 9. The system of claim 1, wherein the ultrasound transducer is configured to deliver the ultrasound beam to a plurality of excitation regions of the material corresponding to the plurality of individually spaced focal regions.
  10. 10. The system of claim 9, wherein the plurality of individually spaced apart focal regions coincide with the plurality of excitation regions.
  11. 11. The system of claim 9, wherein the plurality of individually spaced focal zones are spaced apart from the plurality of excitation zones.
  12. 12. The system of any one of claims 1 to 11, further comprising a movement assembly configured to move the ultrasound probe.
  13. 13. The system of any one of claims 1 to 11, wherein the material comprises an organic material.
  14. 14. The system of any one of claims 1 to 11, wherein the material comprises tissue.
  15. 15. The system of any one of claims 1 to 11, wherein the material comprises skin.
  16. 16. The system of claim 1, wherein the electronic processing system is configured to determine the elasticity of the material in real-time while delivering the ultrasound beam to the material.
  17. 17. The system of any one of claims 1 to 11, configured for use in a cosmetic procedure.
  18. 18. A method of non-invasively measuring elasticity of a material, the method comprising: coupling an ultrasound probe comprising at least one ultrasound transducer with a material; Delivering a plurality of ultrasonic beams from the ultrasonic transducer to the material; focusing the plurality of ultrasonic beams at a plurality of individually spaced focal regions in the material; generating shear waves originating from the plurality of individually spaced focal regions and traveling through the material; imaging the shear waves originating from at least two of the plurality of individually spaced apart focal regions and converging toward a region between the at least two of the plurality of individually spaced apart focal regions through an interrogation region; obtaining characteristics of imaged shear waves, and The elasticity of the query region of the material is determined based on the obtained characteristics.
  19. 19. The method of claim 18, wherein the characteristic of the imaged shear wave comprises at least one of an arrival time of the shear wave, a peak displacement of the shear wave, a rise time of the shear wave, and a fall time of the shear wave.
  20. 20. The method of claim 18, wherein focusing the ultrasound beam at a plurality of individually spaced focal zones in the material comprises modulating an amplitude or frequency of one or more signals driving the ultrasound transducer.

Description

System and method for measuring elasticity using imaging of multi-dimensional ultrasonic multifocal shear waves Incorporated by reference U.S. provisional patent application No. 62/874,374 filed on 7/15/2019 is incorporated herein by reference in its entirety for all purposes. Technical Field Several embodiments of the present invention relate to energy-based non-invasive treatments for obtaining aesthetic and/or cosmetic enhancement effects on the skin and/or tissue near the skin of a person's face, head, neck and/or body by delivering energy to multiple dimensions (e.g., two or more depths, heights, widths, spacing, orientations, placement) of the tissue beneath the skin surface simultaneously or nearly simultaneously. In particular, several embodiments relate to measuring skin elasticity using constructive shear wave imaging by delivering focused energy to multiple dimensions simultaneously or near simultaneously. Background Some cosmetic procedures involve invasive procedures that may require invasive surgery. Patients not only need to tolerate recovery times of several weeks, but also often need to perform dangerous anesthetic procedures. Non-invasive energy-based therapeutic devices and methods are available, but may suffer from various drawbacks in terms of efficiency, effectiveness, and feedback providing efficiency and effectiveness of the treatment. Disclosure of Invention In several embodiments, systems and methods are provided that use targeted and accurate ultrasound to provide feedback regarding the effectiveness of a therapeutic effect by splitting an ultrasound therapy beam into two, three, four or more simultaneous focal zones that produce visible and effective results via thermal paths for performing various therapy and/or imaging procedures. When predetermined therapeutic doses and densities are used, some recipients of a therapeutic procedure may respond more quickly or favorably to treatment due to individual morphology differences from person to person. Thus, feedback on the progress of therapeutic treatment improves efficacy and consistency of results. For therapeutic treatments that result in improved skin and pericutaneous relaxation, a method of measuring tissue elasticity, which is an alternative measure of tissue relaxation during treatment, may provide this feedback. In several embodiments, constructive shear wave imaging (constructive SHEARWAVE IMAGING) measures tissue displacement from a transducer that generates two or more simultaneous focal zones that produce a displacement/velocity profile within the tissue. The tissue response that propagates with this displacement is the shear wave that will converge to a single point for shear wave imaging. The characteristics of converging shear waves, such as arrival time, peak displacement, rise time, and fall time, provide insight into the elasticity of tissue between two or more simultaneous focal zones. Several embodiments described herein are particularly useful for aesthetic and other procedures in which it is beneficial to adjust the treatment parameters in real time (manually or in an automated manner). In embodiments in which a single subject is treated in a single session, one or more parameters, such as frequency, power, intensity, duration, and location of the point of treatment (treatment), are modified based on the elasticity of the tissue beneath the skin surface. When multiple thermal coagulation dotted lines (e.g., two or more) are generated, parameters may be changed between points on the face or body and/or between lines. As an example, if the subject is not sufficiently elastic in a certain area, the duration of the treatment may be prolonged (compared to a skin area with greater elasticity). In some embodiments, one or more of the frequency, power, intensity, duration, or other parameters are changed (increased or decreased) by 10% -30%, 30% -50%, 50% -100%, 2-3 times, 3-5 times, or more, and overlapping ranges therein, and in some embodiments, such changes are correlated and/or elastic-based. In various embodiments, the ultrasound system is configured for focusing ultrasound to produce localized mechanical motion within tissue and cells in order to produce localized heating for tissue coagulation or mechanical cell membrane disruption for non-invasive aesthetic purposes. In various embodiments, the ultrasound system is configured for lifting an eyebrow (e.g., eyebrow lifting). In various embodiments, the ultrasound system is configured for lifting loose, relaxed or sagging tissue, such as under chin (under chin) and neck tissue. In various embodiments, the ultrasound system is configured to improve lines and wrinkles of the neck. In various embodiments, the ultrasound system is configured to reduce fat. In various embodiments, the ultrasound system is configured to reduce the appearance of cellulite. In some embodiments, a system for reducing fat and subsequently treating loose skin caused by fat reduction is pro