CN-114588217-B - Processing method for removing immortal Mao Duxing

Abstract

The invention relates to a processing method of Chinese herbal medicines, which belongs to the field of deep processing of Chinese herbal medicines and discloses a processing method for removing the Chinese herbal medicines Mao Duxing, and comprises the following steps of (1) cleaning, (2) moistening, namely, putting the cleaned Chinese herbal medicines Mao Genjing into yellow wine, moistening, (3) steaming, namely, putting the moistened Chinese herbal medicines Mao Dexia rootstock into a high-pressure steamer for steaming, (4) cooling, namely, cooling the steamed Chinese herbal medicines Mao Dexia rootstock to room temperature, (5) pre-freezing, namely, putting the cooled Chinese herbal medicines Mao Dexia rootstock into a pre-freezing cabinet for low-temperature freezing, (6) vacuum freeze-drying, namely, the pre-frozen Chinese herbal medicines Mao Dexia rootstock, and vacuum-drying in a vacuum freezing cabinet, and (7) heating, namely, after freeze-drying, raising the temperature in the freezing cabinet to the room temperature.

Inventors

• YANG TIANMEI
• ZHANG JINYU
• YANG MEIQUAN
• XU ZONGLIANG
• ZENG XIANGFEI
• LI JICHAO
• ZHU XINYAN
• QI MINGJU

Assignees

• 云南省农业科学院药用植物研究所
• 云南植虫药生物科技有限公司

Dates

Publication Date

20260512

Application Date

20220304

Claims (3)

1. 1. A processing method for removing the immortal Mao Duxing is characterized by comprising the following steps: (1) Cleaning, namely taking the rhizome of the immortal Mao Dexia, and cleaning soil; (2) Moistening, namely placing the cleaned rhizome of the immortal Mao Dexia into yellow wine for moistening; (3) Steaming, namely steaming the root and stem of the stuffy herb Mao Dexia which is stewed and moistened in an autoclave; (4) Cooling, namely cooling the steamed rhizome of the immortal Mao Dexia to room temperature; (5) Prefreezing, namely placing the cooled rhizome of the immortal Mao Dexia into a prefreezing cabinet for low-temperature freezing; (6) Vacuum freeze drying, namely performing ultralow-temperature vacuum drying on the pre-frozen rhizome of the immortal Mao Dexia in a vacuum freezer; (7) Heating, namely heating the mixture to room temperature in a freezer after freeze drying; The mass ratio of the curculigo rhizome to the yellow wine which is moistened by the yellow wine in the step (2) is 10:1, and the moistening time is 20-24 hours; the steaming temperature in the step (3) is 125-138 ℃, and the steaming time is 15-20 min.
2. 2. The processing method for removing the immortal Mao Duxing according to claim 1, wherein the prefreezing temperature in the step (5) is minus 12-15 ℃ and the prefreezing time is 10-12 hours.
3. 3. The processing method for removing the immortal Mao Duxing according to claim 1, wherein the vacuum freeze-drying temperature in the step (6) is minus 45-50 ℃, the vacuum is kept at 10-15 Pa, and the freeze-drying time is 12-13 hours.

Description

Processing method for removing immortal Mao Duxing Technical Field The invention relates to a processing method of a traditional Chinese medicine, belongs to the field of deep processing of traditional Chinese medicines, and particularly relates to a processing method of a traditional Chinese medicine curculigo rhizome. Background The rhizoma Curculiginis is dried rhizome of Curculigo orchioides (Curculigo orchioides Gaertn.) belonging to Amaryllidaceae, and is mainly produced in Yunnan, sichuan, guizhou, zhejiang, jiangxi, fujian, taiwan, guangdong, guangxi, hunan, and also distributed in southeast Asia to Japan. It mainly grows in forests, grasslands or barren slopes with an altitude below 1600 meters. Xian Mao Xingxin, which is hot and toxic, has effects of invigorating kidney yang, strengthening tendons and bones, and dispelling dampness and cold, and can be used for treating sexual impotence, cold sperm, lumbago, knee pain, yang deficiency, cold diarrhea, etc. The curculiginis Mao Nahan curculiginis glycoside is the most important index for evaluating the quality of curculigo rhizome medicinal materials, is also the main index of the market price of curculigo rhizome medicinal materials, has the functions of resisting oxidation, resisting inflammation, regulating immunity, resisting osteoporosis, tonifying kidney, strengthening yang and the like, and is mainly applied to treating symptoms such as impotence, cold sperm, flaccidity of bones and muscles, cold pain of waist and knees, yang deficiency and diarrhea and the like clinically at present. According to the modern medicine research data and the ancient medical records, because the curculigo rhizome has little toxicity, the toxic substance is lycorine, which can cause toxic reactions such as whole body cold sweat, limb syncope, numbness, tongue swelling, dysphoria, coma and the like, Therefore, the curculigo rhizome needs to be processed before use, and the purpose of processing is detoxification and retaining active substances to the greatest extent. The existing processing method can only reduce but not completely remove the toxicity of curculigo rhizome, and part of processing method can completely inactivate the lycoris base which is a toxic component, thereby removing the toxicity, but also reduces the content of effective components such as curculin in curculigo rhizome medicinal materials to a certain extent, so that the drug effect is rapidly reduced, and part of processing method can reduce the loss of the effective components such as curculin, but also only slightly reduces the content of lycorine in curculigo rhizome. When curculigo rhizome is taken as prescription medicine, the toxicity can be controlled in a controllable range because the dosage is strictly controlled, but as the proportion of the curculigo rhizome Mao Zaibao health product industry becomes larger, the curculigo rhizome can not completely remove the toxicity, and the industry of the curculigo rhizome as health care raw material and even food raw material can be blocked to a great extent. Aiming at the defects that active ingredients such as curculigoside and the like cannot be reserved to the greatest extent and toxic substances such as lycorine cannot be completely removed in the prior art, the invention provides an important active substance such as curculigoside and the like which is simple in process and stable in property and can be used for completely removing curculigoside and the like based on the former technology and combining with modern advanced technologies. Disclosure of Invention The invention mainly aims to provide a processing method for removing the immortal Mao Duxing so as to solve the problems in the background technology. In order to achieve the above purpose, the invention is realized by the following technical scheme: 1. cleaning, namely taking the rhizome of the immortal Mao Dexia, removing bud heads, and cleaning the soil on the surface. 2. Moistening, namely, uniformly stirring the cleaned rhizome of the immortal Mao Dexia with yellow wine according to the mass ratio of the curculigo rhizome to the yellow wine of 10:1 after draining water, and moistening for 20-24 hours, wherein stirring is carried out every 3-4 hours, so that moistening is more complete. 3. Steaming, namely draining the rhizome of the immortal Mao Dexia after the moistening, placing the rhizome in an autoclave, and steaming for 15-20 min at the temperature of 125-128 ℃. 4. Cooling, namely spreading the rhizome of the immortal Mao Dexia on a drying disc after steaming, and cooling to room temperature. 5. Pre-freezing, namely placing the cooled rhizome of the immortal Mao Dexia into a pre-freezing cabinet, adjusting the temperature to be minus 12-15 ℃, and freezing for 10-12 hours. 6. Vacuum freeze drying, namely placing the pre-frozen rhizome of the immortal Mao Dexia into a vacuum drying and freezing cabinet, adjusting the temperature to 45-50 ℃ below zero, vacuumizing and ke