CN-115363519-B - Wide-angle pupil repeater of fundus camera based on mobile phone

CN115363519BCN 115363519 BCN115363519 BCN 115363519BCN-115363519-B

Abstract

An optical imaging system includes a first lens system housed in a body of a mobile communication device, the first lens system having a first optical axis, a first entrance pupil spatially fixed in a reference plane associated with the body, and a first focal length, and an optical telescope providing diffraction-limited imaging in a spectral range of at least 486nm to at least 656 nm. The optical imaging system is configured to image the EPE onto the first entrance pupil at a base unit magnification when the optical telescope is interposed between the first lens system and the entrance pupil of the eye vision system, i.e., the EPE, and vice versa.

Inventors

STURMAN GRAHAM

Assignees

株式会社尼康
株式会社尼康

Dates

Publication Date: 20260421
Application Date: 20170831
Priority Date: 20170831

Claims (7)

1. An optical imaging system, comprising: A first lens system housed in a body of a mobile communication device, the first lens system having a first optical axis, a first entrance pupil spatially fixed in a reference plane associated with the body, and a first focal length, and An optical telescope providing diffraction-limited imaging over a spectral range of at least 486nm to at least 656nm, Wherein the optical imaging system is configured to image an EPE onto the first entrance pupil of the eye vision system at a base unit magnification when the optical telescope is interposed between the first lens system and the entrance pupil, or EPE, and vice versa.
2. The optical imaging system of claim 1, further comprising: A second lens system housed in the body of the communication device, the second lens system having a second optical axis, a spatially fixed second entrance pupil in the reference plane, the second entrance pupil being laterally offset from the first entrance pupil in the reference plane, and a second focal length, an Means for connecting the optical telescope to the body, the means configured to provide movement of the optical telescope from a first position to a second position along a line lying in the reference plane, wherein: The first position is defined when the optical axis of the optical telescope and the first optical axis substantially coincide, The second position is defined when the optical axis of the optical telescope and the second optical axis at least partially coincide.
3. The optical imaging system of claim 2, wherein the first optical axis and the second optical axis are substantially parallel to each other.
4. The optical imaging system of claim 2, wherein the optical imaging system is configured to image the EPE onto the first entrance pupil at a base unit magnification and vice versa when the optical telescope is interposed between the second lens system and the EPE.
5. The optical imaging system of claim 1, wherein the first lens system comprises a meniscus lens element with negative optical power cemented with a positive lens element to form an optical doublet, and a positive optical power lens element spatially separated from the optical doublet.
6. A method of imaging a retina, the method comprising: positioning an optical telescope between a first lens system built into a communication device and an eye to image an entrance pupil of the eye, i.e., an EPE, onto the first entrance pupil of the first lens system, i.e., the EP, under imaging conditions including (i) unit magnification and (ii) diffraction-limited imaging in a spectral range of 486nm to 656nm, and A first image of a retina of the eye is recorded by the optical telescope with a first sensor of the communication device.
7. The method of claim 6, the method further comprising: Repositioning the optical telescope and the communication device relative to each other in a direction transverse to the optical axis of the first lens system until the optical axis of a second lens system built into the communication device substantially coincides with the optical system of the optical telescope, and A second image of the retinal surface is recorded by the optical telescope with a second sensor of the communication device.

Description

Wide-angle pupil repeater of fundus camera based on mobile phone The present invention is a divisional application of the invention application of international application date 2017, 8-31, international application number PCT/JP2017/031412, national application number 201780053096.X entering the national stage of china, and the invention name "wide-angle pupil repeater of fundus camera based on mobile phone". Technical Field The present invention is technically directed to U.S. provisional patent application 62/381,768 filed on day 2016, 8, 31 and U.S. provisional patent application 62/539,733 filed on day 8, 2017. The disclosures of these provisional applications are incorporated herein by reference. The present invention relates generally to eye diagnostic imaging devices and more particularly to a portable, hand-held smartphone-based retinal camera for capturing high quality wide field-of-view fundus images. The use of a mobile phone platform creates a fully embedded system that can acquire, store and analyze fundus images that can be transmitted directly from the phone through a wireless communication system for remote evaluation. Background Fundus imaging is widely used for diagnosis, monitoring and management of many retinal diseases. One limitation found in current imaging systems is the bulky and stationary nature of the imaging device. Conventional fundus cameras are cumbersome tabletop devices that are not easily moved due to the vulnerability, large size, and weight of these devices. In practice, such fundus cameras also force the patient to sit upright, which can be difficult for patients with illness and hospitalization. In addition to the size limitations, fundus cameras also require a power source to power the illumination, imaging screen, and data processing unit. Typically, this power is provided by a center wall plug and requires continuous power to operate the fundus camera properly. While digital fundus cameras (some of which are based on cell phones or similar devices, such as iphones; typically mobile devices) have been envisaged, these cameras have substantial operational limitations caused by any of (i) a lack of optical conjugation between the optical system of the mobile device being used and the visual system being imaged, (ii) an insufficient field of view (FOV) associated with imaging of the selected surface of the visual system, which results in the need to perform multiple calculations "stitching" of the acquired images, (iii) severe residual aberrations damaging the resulting images, and (iv) combinations of the foregoing. Thus, there remains a need for a low cost handheld device that is configured to be used as a replacement for high cost medical devices and that is capable of recording digital images of the surface of the vision system during its ophthalmic examination, while not characterizing the operational drawbacks of currently known imaging system solutions. Disclosure of Invention A first aspect of the present disclosure includes a first lens system housed in a body of a mobile communication device, the first lens system having a first optical axis, a first entrance pupil spatially fixed in a reference plane associated with the body, and a first focal length, and an optical telescope providing diffraction-limited imaging over a spectral range of at least 486nm to at least 656nm, wherein the optical imaging system is configured to image an EPE onto the first entrance pupil at a basic unit magnification when the optical telescope is interposed between the first lens system and the entrance pupil of the eye vision system, the EPE, and vice versa. Drawings The invention will be more fully understood by reference to the following detailed description of specific embodiments in conjunction with the accompanying drawings, which are not to scale. Fig. 1 is a diagram showing a mobile phone 20, which mobile phone 20 is provided with an image capturing section (camera sensor) 214 that captures an image of the fundus of the subject's eye via a window 214W and via an optical system (image capturing lens system (camera lens)) not shown, and shows an accessory 22 attached to the mobile phone 20. Fig. 2 is a schematic diagram of an optical assembly of a first embodiment that supplements the exit pupil of a portable device and relays an image of the cell phone camera pupil onto the eye pupil. Fig. 3 includes a plot of diffraction-limited imaging quality for characterizing the first embodiment of fig. 2 for different field heights. Fig. 4 shows a second embodiment of an optical assembly 500, which represents an afocal relay system configured with the inventive concepts and is shown in combination with the navaro model of the human eye. Fig. 5 shows a dot diagram of the second embodiment of fig. 4 for different field heights. Fig. 6A is a diagram showing a dimensional relationship between an image capturing field of view of the fundus in the first embodiment and an image sensor. Fig.