CN-115475315-B - Electronic gasifier system and control method thereof

CN115475315BCN 115475315 BCN115475315 BCN 115475315BCN-115475315-B

Abstract

An electronic vaporizer system includes an anesthetic reservoir containing an anesthetic agent, a vaporizer unit vaporizing the anesthetic agent from the reservoir and delivering the vaporized agent to a patient breathing circuit, and a gas sensor configured to measure an end-tidal concentration of the anesthetic agent in exhaled gas from the patient. The control system is configured to receive the measured end-tidal concentration of the anesthetic agent and compare the measured end-tidal concentration to a desired end-tidal concentration to be maintained by the patient. The vaporizer unit is then automatically controlled to deliver an amount of vaporized reagent to the patient based on the comparison.

Inventors

Joseph J. Lacey
R.J. Kuzelka

Assignees

通用电气精准医疗有限责任公司

Dates

Publication Date: 20260505
Application Date: 20220608
Priority Date: 20210614

Claims (19)

1. An electronic gasifier system, the electronic gasifier system comprising: an anesthetic reservoir containing an anesthetic; A vaporizer unit that vaporizes the anesthetic agent from the reservoir and delivers the anesthetic agent to a patient breathing circuit; a gas sensor configured to measure end-tidal concentration of the anesthetic agent in exhaled gas from the patient; A control system configured to: receiving a measured end-tidal concentration of the anesthetic; comparing the measured end-tidal concentration with a desired end-tidal concentration to be maintained by the patient, and Automatically controlling the vaporizer unit to deliver an amount of anesthetic agent to the patient breathing circuit based on the comparison, Wherein the control system is further configured to: Receiving one or more concentration normals, and And automatically adjusting the expected end-tidal concentration according to the concentration routine value.
2. The system of claim 1, further comprising at least one ventilation gas sensor configured to sense a flow rate of inhaled gas in the breathing circuit; Wherein the control system is further configured to control the vaporizer unit to deliver the amount of anesthetic agent to the patient breathing circuit based on the flow rate of the inhalation gas.
3. The system of claim 1, wherein the control system is configured to determine a change in the amount of anesthetic agent to be delivered to the patient breathing circuit based on a difference between the measured end-tidal concentration and a desired end-tidal concentration, and to control the vaporizer unit to effect the change.
4. The system of claim 1, further comprising an anesthesia depth monitor configured to measure an anesthesia depth of the patient; wherein the control system is further configured to: determining that the difference between the measured depth of anesthesia and the desired depth of anesthesia exceeds a threshold value, and A new desired end-tidal concentration is determined based on a difference between the measured depth of anesthesia and a desired depth of anesthesia.
5. The system of claim 1, wherein the desired end-tidal concentration is received from a clinician via a user interface on the vaporizer system.
6. The system of claim 1, wherein the sump and the gasifier unit are housed together in a housing.
7. The system of claim 6, further comprising a touch screen on the housing configured to receive control inputs for the vaporizer system and display at least one of the measured end-tidal concentration, the desired end-tidal concentration, and a difference between the measured end-tidal concentration and the desired end-tidal concentration.
8. The system of claim 6, wherein the housing is configured to be removably attached to a ventilator system configured to ventilate the patient.
9. The system of claim 6, further comprising an anesthesia depth monitor configured to connect to a sensor and measure an anesthesia depth of the patient, wherein the anesthesia depth monitor is housed within the housing.
10. The system of claim 6, further comprising a dial on the housing movable to control a mode of the vaporizer system between a manual mode in which a clinician manually controls the amount of anesthetic agent delivered to the patient breathing circuit and an automatic mode in which the control system automatically controls the vaporizer unit to deliver the amount of anesthetic agent to the patient breathing circuit.
11. The system of claim 1, wherein the control system is further configured to: A suggested concentration is calculated based on patient demographics and the desired end-tidal concentration is adjusted based on the suggested concentration.
12. An apparatus to control a vaporizer system configured to vaporize an anesthetic agent and deliver the anesthetic agent to a patient breathing circuit, the apparatus comprising: display unit, and A processor configured with instructions in a non-transitory memory that, when executed, cause the processor to: measuring the end-tidal concentration of the anesthetic in exhaled gas from the patient; Comparing the measured end-tidal concentration with an end-tidal concentration to be maintained by the patient, and Automatically controlling a vaporizer unit to deliver an amount of anesthetic agent to the patient breathing circuit based on the comparison, so as to maintain the measured end-tidal concentration within a predetermined range of desired end-tidal concentrations, Wherein the instructions, when executed, further cause the processor to: Receiving one or more concentration routine values selected by a clinician, and The desired end-tidal concentration is automatically adjusted according to the selected concentration routine.
13. The device of claim 12, wherein the instructions, when executed, further cause the processor to: Sensing the flow rate of inhaled gas in the breathing circuit, and The vaporizer unit is further controlled to deliver the amount of anesthetic agent to the patient breathing circuit based on the flow rate of the inhalation gas.
14. The device of claim 12, wherein the instructions, when executed, further cause the processor to: A change in the amount of the anesthetic agent to be delivered to the patient breathing circuit is determined based on a difference between the measured end-tidal concentration and a desired end-tidal concentration, and the vaporizer unit is controlled to effect the change.
15. The device of claim 12, wherein the instructions, when executed, further cause the processor to: measuring the depth of anesthesia of the patient; determining that the difference between the measured depth of anesthesia and the desired depth of anesthesia exceeds a threshold value, and A new desired end-tidal concentration is determined based on a difference between the measured depth of anesthesia and a desired depth of anesthesia.
16. The device of claim 12, wherein the instructions, when executed, further cause the processor to: A dial position of a dial on the vaporizer system associated with an automatic mode is sensed prior to automatically controlling the vaporizer unit to deliver the amount of anesthetic agent to the patient breathing circuit.
17. The device of claim 12, wherein the instructions, when executed, further cause the processor to: Sensing the N 2 O concentration of the inhaled gas in the breathing circuit, and The desired end-tidal concentration is determined based on the N 2 O concentration.
18. The device of claim 12, wherein the instructions, when executed, further cause the processor to: Receiving, from a network computer, a suggested concentration calculated based on patient demographics of the patient; comparing the desired end-tidal concentration to the proposed concentration; Determining a concentration variation recommendation based on the comparison, and Displaying the concentration variation advice on the display of the gasifier system.
19. The device of claim 18, wherein the instructions, when executed, further cause the processor to: Automatically adjusting the desired end-tidal concentration based on the suggested concentration.

Description

Electronic gasifier system and control method thereof Background The present disclosure relates generally to anesthetic delivery systems, and more particularly to vaporizer systems that deliver vaporized anesthetic to a patient's breathing circuit. Anesthetic agents induce a patient to enter a hypnotic state by administering such agents, such as by inhaling the agents through the patient's respiratory circuit. Typical inhalation anesthetics include sevoflurane, isoflurane, desflurane, an Fu ethers, and the like. These inhalation anesthetics are typically stored in liquid form and then vaporized in a vaporizer system. Vaporized anesthetic agents are mixed into fresh gas and other ventilation gases delivered to the patient. Various types of anesthetic vaporizers are well known in the relevant art, including booster vaporizers, distillation vaporizers, and dual circuit gas-vapor blenders. The anesthetic acts on the brain, weakening or losing the patient's consciousness. The degree to which a patient is anesthetized is commonly referred to as the "depth of anesthesia" or "hypnotic level". The depth of anesthesia of a patient may be measured using various patient monitoring devices, such as a brain electrical double frequency index (BIS) monitor, which analyzes the complexity of electroencephalogram (EEG) data obtained from the patient as an indication of the sensed hypnotic level of the patient. Other anesthesia depth monitoring methods and systems are also known, including four serial stimulation monitors, facial twitch monitors, and the like. Disclosure of Invention This summary is provided to introduce a selection of concepts that are further described below in the detailed description. This summary is not intended to identify key or essential features of the claimed subject matter, nor is it intended to be used as an aid in limiting the scope of the claimed subject matter. In one embodiment, an electronic vaporizer system includes an anesthetic agent reservoir containing an anesthetic agent, a vaporizer unit vaporizing the anesthetic agent from the reservoir and delivering the vaporized agent to a patient breathing circuit, and a gas sensor configured to measure an end-tidal concentration of the anesthetic agent in exhaled gas from the patient. The control system is configured to receive the measured end-tidal concentration of the anesthetic agent and compare the measured end-tidal concentration to a desired end-tidal concentration to be maintained by the patient. The vaporizer unit then automatically controls delivery of a controlled amount of a vaporized reagent to the patient based on the comparison. In one embodiment, a method of controlling a vaporizer system configured to vaporize an anesthetic agent and deliver the vaporized agent to a patient breathing circuit includes measuring an end-tidal concentration of the anesthetic agent in exhaled gas from the patient and comparing the measured end-tidal concentration to a desired end-tidal concentration to be maintained by the patient. The vaporizer unit is then automatically controlled based on the comparison to deliver an amount of vaporized reagent to the patient breathing circuit to maintain the measured end-tidal concentration within a predetermined range of the desired end-tidal concentration. Various other features, objects, and advantages of the present invention will become apparent from the following description taken in conjunction with the accompanying drawings. Drawings The present disclosure is described with reference to the following drawings. Fig. 1 depicts one embodiment of an electronic vaporizer system connected to a ventilator system to deliver anesthetic agents to a patient. Fig. 2 depicts another embodiment of an electronic vaporizer system connected to a ventilator system to deliver anesthetic agents to a patient. Fig. 3 depicts an exemplary table for calculating recommended end-tidal concentrations of an exemplary anesthetic sevoflurane based on patient demographics and other information. Fig. 4-6 depict a method or portion thereof of controlling an electronic vaporizer system for delivering an anesthetic agent to a patient. Detailed Description As described above, the vaporizer aspirates a liquid anesthetic agent (such as sevoflurane or desflurane) and converts it to vapor, which is titrated to the patient. The patient inhales anesthetic vapors through the breathing gas delivered by the ventilator. Mechanically controlled gasifier systems are a very common type of gasifier system worldwide. Mechanical gasifiers are open loop control systems in which a clinician sets the delivered-quantity of the gasifier, such as by controlling a dial on the housing of the gasifier system. Depending on the needs of the patient and the desired depth of anesthesia or hypnotic level, the clinician manually adjusts the amount of agent delivered by the manual vaporizer based on the medical care provided to the patient. The present inventors have recogn