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CN-115541913-B - Sampling mechanism and sampling system comprising same

CN115541913BCN 115541913 BCN115541913 BCN 115541913BCN-115541913-B

Abstract

The invention provides a sample adding mechanism and a sample adding system comprising the same. The sampling mechanism includes a transfer channel having a transfer channel first opening in communication with the container outside to allow the reagent in the container to enter the transfer channel and a transfer channel second opening in communication with the outside of the transfer channel to allow the reagent to leave the transfer channel, a transfer mechanism disposed in the transfer channel and adapted to be driven to move to transfer the reagent in the transfer channel to the transfer channel second opening, and to control the mass flow rate of the reagent leaving through the transfer channel second opening by adjusting the speed of the movement itself. By adopting the automatic weighing and sampling device, the automation of weighing and sampling of the reagent is realized, the weighing error and the reagent pollution caused by manual weighing and sampling are avoided, and the reagent, especially the powder reagent, can be accurately weighed and sampled.

Inventors

  • ZHUO LI

Assignees

  • 时新(上海)产品设计有限公司

Dates

Publication Date
20260508
Application Date
20220929

Claims (17)

  1. 1. A sampling mechanism (100), comprising: A transfer passage (111, 126) having a transfer passage first opening (111 a, 126 a) communicating with an external container (211) to allow a reagent within the container (211) to enter the transfer passage (111, 126), and a transfer passage second opening (111 b) communicating with an outside of the transfer passage (111, 126) to allow the reagent to leave the transfer passage (111, 126); A transport mechanism disposed within the transport channel (111, 126) and adapted to be driven to move to transport the reagent within the transport channel (111, 126) to the transport channel second opening (111 b) and to control the mass flow of the reagent exiting through the transport channel second opening (111 b) by adjusting the speed of movement of itself, The conveying channels (111, 126) comprise a first channel (111), the conveying mechanism comprises at least one first screw (112) arranged in the first channel (111), the sampling mechanism (100) further comprises a second channel (113), at least one second screw (114) arranged in the second channel (113), an end cam (115) coaxially connected with the top end of the first screw (112), a first gear (116) coaxially connected with the top end of the second screw (114), a top cover (117) arranged above the first channel (111) and the second channel (113), and a cam matching piece (119) arranged between the top cover (117) and the end cam (115) and only suitable for moving along the axial direction of the first screw (112), the end cam (115) is in meshed transmission connection with the first gear (116) and is suitable for rotating in a first direction under the driving of the first screw (112), and the first gear (114) is driven to rotate in a first direction and the first cam (115) is driven to reciprocate along the first direction when the first cam (115) is driven to rotate in the first direction and the first cam (115) is driven to reciprocate along the first direction (116) along the first axial direction, and restricting rotation of the face cam (115) in the second direction.
  2. 2. The sampling mechanism (100) according to claim 1, wherein the transport channel first opening (111 a, 126 a) comprises a first channel first opening (111 a), and the transport channel second opening (111 b) comprises a first channel second opening (111 b); The first screw (112) is adapted to be driven in rotation in a first direction to convey the reagent in the first channel (111) to the first channel second opening (111 b), and to control the mass flow of the reagent exiting through the first channel second opening (111 b) by adjusting the rotational speed of itself.
  3. 3. The sampling mechanism (100) according to claim 2, wherein the second channel (113) has a second channel first opening (113 a) in communication with the first channel second opening (111 b) to allow reagents within the first channel (111) to enter the second channel (113), a second channel second opening (113 b) in communication with the outside to allow the reagents to leave the second channel (113), and a second channel third opening (113 c) in communication with the container (211) to allow the reagents to leave the second channel (113) back to the container (211), the second screw (114) being in driving connection with the first screw (112) to rotate in a second direction under the drive of the first screw (112) to convey reagents within the second channel (113) to the second channel second opening (113 b) and the second channel third opening (113 c).
  4. 4. A sampling mechanism (100) according to claim 3, wherein the first channel first opening (111 a) is located at a middle side of the first channel (111), the first channel second opening (111 b) is located at a lower side of the first channel (111), the second channel first opening (113 a) is located at a lower side of the second channel (113), the second channel second opening (113 b) is located at a bottom end of the second channel (113), and the second channel third opening (113 c) is located at an upper side of the second channel (113).
  5. 5. A sampling mechanism (100) according to claim 3, wherein the tip of the first screw (112) extends outside the first channel (111) and the tip of the second screw (114) extends outside the second channel (113).
  6. 6. The sampling mechanism (100) according to claim 5, further comprising an elastic member (118) located between the top cover (117) and the end cam (115) and adapted to move only in the axial direction of the first screw (112), the elastic member (118) being adapted to compress and release the compression under the action of the cam mating member (119) when the end cam (115) rotates in the first direction.
  7. 7. The sampling mechanism (100) of claim 6, wherein the end surface cam (115) has a pair of first inclined surfaces (115 a) and a pair of first vertical surfaces (115 b) at an end facing the cam mating member (119), wherein the end surface cam (119) has a pair of second inclined surfaces (119 a) and a pair of second vertical surfaces (119 b) at an end facing the end surface cam (115), wherein the first inclined surfaces (115 a) engage the second inclined surfaces (119 a), wherein the first vertical surfaces (115 b) engage the second vertical surfaces (119 b), wherein the first vertical surfaces (115 b) are spaced apart from the second vertical surfaces (119 b) with which they engage when the end surface cam (115) is rotated in the first direction, wherein the first inclined surfaces (115 a) are rotated relative to the second inclined surfaces (119 a) with which they engage and urge the cam mating member (119) to reciprocate in the axial direction of the first screw (112), and wherein the second vertical surfaces (119 b) are prevented from rotating in the second direction when the end surface cam (115) is rotated in the second direction.
  8. 8. The sampling mechanism (100) according to claim 6 or 7, wherein the cam fitting (119) includes a guide block (119 c) provided at a side portion thereof, and the side portion of the top cover (117) has a guide groove extending in an axial direction of the first screw (112) to receive the guide block (119 c) and allow the guide block (119 c) to reciprocate therein in the axial direction of the first screw (112).
  9. 9. The sampling mechanism (100) according to claim 6, wherein the tip of the first screw (112) passes through the end face cam (115) and the cam fitting member (119) in this order and extends above the cam fitting member (119), the cam fitting member (119) has a support edge (119 d) provided with an inner ring thereof, the elastic member (118) comprises a spring which is fitted over the tip of the first screw (112) and both ends of which abut respectively the inner end face of the cap (117) and the support edge (119 d), and which is adapted to compress when the cam fitting member (119) moves upward in the axial direction of the first screw (112), and release the compression to move the cam fitting member (119) downward in the axial direction of the first screw (112) so that the cam fitting member (119) is adapted to reciprocate in the axial direction of the first screw (112).
  10. 10. A sampling mechanism (100) according to claim 3, wherein the sampling mechanism (100) further comprises an outlet valve (120) adapted to close and open the second channel second opening (113 b), the outlet valve (120) being rotatably connected to an end of the second channel (113) adjacent to the second channel second opening (113 b) and adapted to be driven to rotate in a third direction to close the second channel second opening (113 b) and to rotate in a fourth direction to open the second channel second opening (113 b), wherein the fourth direction is opposite to the third direction.
  11. 11. The sampling mechanism (100) according to claim 10, wherein the outlet valve (120) comprises a closing portion (121), the closing portion (121) comprising a seal adapted to be arranged facing the second channel second opening (113 b), the seal being adapted to gradually approach and face the second channel second opening (113 b) to be adapted to embed the second channel second opening (113 b) to close it when the outlet valve (120) is rotated in the third direction, and to disengage from the second channel second opening (113 b) and to open the outlet valve (120) away from the second channel second opening (113 b) when the outlet valve (120) is rotated in the fourth direction.
  12. 12. The sampling mechanism (100) according to claim 11, further comprising a catch block (123) arranged outside the second channel (113), wherein the outlet valve (120) comprises a catch portion (122) connected to the closing portion (121) and bent with respect to the closing portion (121) to be adapted to face a side of the second channel (113), wherein the catch portion (122) comprises a catch groove (122 a) arranged towards the catch block (123), wherein the catch groove (122 a) is adapted to move towards the catch block (123) upon rotation of the outlet valve (120) in the third direction and to be retained by the catch block (123) upon movement to the catch block (123) such that the sealing member faces and engages the second channel second opening (113 b), and to leave the catch block (123) upon rotation of the outlet valve (120) in the fourth direction.
  13. 13. The sampling mechanism (100) according to claim 12, wherein the hook groove (122 a) abuts against the bottom of the hook block (123) to limit the upward movement of the outlet valve (120) when the hook groove (122 a) is limited by the hook block (123).
  14. 14. The sampling mechanism (100) according to claim 1, wherein the transport channel (111, 126) comprises a third channel (126), the transport channel first opening (111 a, 126 a) comprises a third channel first opening (126 a), and the transport channel second opening (111 b) comprises a third channel second opening; The transport mechanism comprises a conveyor belt (127) arranged in the third channel (126), the conveyor belt (127) being adapted to be driven for transmission and to receive reagents from the third channel first opening (126 a) and to transport the reagents to the third channel second opening during transmission.
  15. 15. The sampling mechanism (100) according to claim 14, wherein the conveyor belt (127) comprises a first conveyor section (127 a) and a second conveyor section (127 b) that continuously vary during the transmission, the first conveyor section (127 a) being adapted to convey the reagent to the third channel second opening, the second conveyor section (127 b) being adapted to convey the reagent that does not leave through the third channel second opening back to the third channel (126).
  16. 16. The sampling mechanism (100) of claim 15, wherein the third channel (126) has a third channel third opening in communication with the container (211) to allow reagents that do not exit through the third channel second opening to return into the container (211).
  17. 17. A sample application system (500), comprising: The sampling mechanism (100) according to any one of claims 1 to 16, adapted to deliver a reagent within the container (211) into a reagent bottle outside the container (211); a balance (510) disposed below the reagent bottle adapted to weigh the mass of reagent delivered into the reagent bottle; A controller (520) coupled to the balance (510) and the sampling mechanism (100), respectively, and adapted to adjust the speed of movement of the transport mechanism based on the mass.

Description

Sampling mechanism and sampling system comprising same Technical Field The invention relates to the technical field of weighing and sampling, in particular to a sampling mechanism and a sampling system comprising the same. Background It is well known that in biochemical experiments, it is often necessary to perform a weighing and sampling operation on reagents, especially powdered reagents. However, the weighing balance commonly used at present not only needs manual operation, but also has low accuracy and large error. Moreover, since the manual operation is performed, the sample is taken by the sense of a person every time the operation is performed, and thus it may be difficult to achieve an ideal weighing and sampling effect through a plurality of operations. In addition, due to manual operation, the reagent may be dropped or scattered during the movement of the sample, which may not only result in reagent waste, but also may cause reagent pollution. Disclosure of Invention The embodiment of the invention provides a sample adding mechanism and a sample adding system comprising the same, which not only realize the automation of reagent weighing and sampling and avoid weighing errors and reagent pollution caused by manual weighing and sampling, but also can accurately weigh and sample reagents, especially powder reagents. Therefore, the embodiment of the invention provides the following technical scheme: the embodiment of the invention provides a sample adding mechanism and a sample adding system comprising the same. The sampling mechanism comprises a conveying channel, a conveying mechanism and a conveying mechanism, wherein the conveying channel is provided with a conveying channel first opening communicated with an external container for allowing reagents in the container to enter the conveying channel and a conveying channel second opening communicated with the outside of the conveying channel for allowing the reagents to leave the conveying channel, the conveying mechanism is arranged in the conveying channel and is suitable for being driven to move so as to convey the reagents in the conveying channel to the conveying channel second opening, and the mass flow rate of the reagents leaving through the conveying channel second opening is controlled by adjusting the speed of the movement of the conveying mechanism. Optionally, the conveying channel comprises a first channel, the first opening of the conveying channel comprises a first opening of the first channel, the second opening of the conveying channel comprises a second opening of the first channel, the conveying mechanism comprises at least one first screw arranged in the first channel, the first screw is suitable for being driven to rotate in a first direction to convey the reagent in the first channel to the second opening of the first channel, and the mass flow rate of the reagent leaving through the second opening of the first channel is controlled by adjusting the rotation speed of the first screw. Optionally, the sampling mechanism further comprises a second channel and at least one second screw arranged in the second channel, wherein the second channel is provided with a second channel first opening communicated with the first channel second opening so as to allow reagents in the first channel to enter the second channel, a second channel second opening communicated with the outside so as to allow the reagents to leave the second channel, and a second channel third opening communicated with the container so as to allow the reagents to leave the second channel and return to the container, the second screw is in meshed transmission connection with the first screw so as to rotate along a second direction under the driving of the first screw so as to convey the reagents in the second channel to the second channel second opening and the second channel third opening, and the second direction is opposite to the first direction. Optionally, the first channel first opening is located at the middle side part of the first channel, the first channel second opening is located at the lower side part of the first channel, the second channel first opening is located at the lower side part of the second channel, the second channel second opening is located at the bottom end of the second channel, and the second channel third opening is located at the upper side part of the second channel. Optionally, the top end of the first screw rod extends out of the first channel, the top end of the second screw rod extends out of the second channel, the sampling mechanism comprises an end cam coaxially connected with the top end of the first screw rod and a first gear coaxially connected with the top end of the second screw rod, the end cam is in meshed transmission connection with the first gear and is suitable for being driven by the first screw rod to rotate in the first direction, and the first gear is driven to drive the second screw rod to rotate in the second di