CN-115968307-B - Blood purifying device

Abstract

A blood purification device for returning blood in a blood circuit to the body is provided, wherein the blood circuit and a dialysis liquid circuit circulate liquid through each other via a blood purification membrane of a blood purifier, and the blood purification device comprises a1 st flow path and a2 nd flow path, wherein the 1 st flow path allows dialysis liquid to flow into the blood circuit from the dialysis liquid circuit via a connection flow path, the connection flow path bypasses the blood purifier to connect the dialysis liquid circuit and the blood circuit, and the 2 nd flow path allows dialysis liquid to flow into the blood circuit from the dialysis circuit via the blood purification membrane. The control device performs control so as to return blood in the blood circuit to the body by flowing the dialysis liquid in one of the 1 st and 2 nd channels, determines whether or not the flow rate of the dialysis liquid has reached a predetermined flow rate, and controls so as to return blood in the blood circuit to the body by flowing the dialysis liquid in the other of the 1 st and 2 nd channels in response to the determination that the flow rate of the dialysis liquid has reached the predetermined flow rate.

Inventors

• SENSHU
• Mao Shouyouzai
• SHI HEYE
• AKITA KUNIHIKO

Assignees

• 日机装株式会社

Dates

Publication Date

20260508

Application Date

20210607

Priority Date

20200709

Claims (11)

1. 1. A blood purification device comprising a blood circuit, a dialysate circuit, and a control device, wherein liquid can flow through a blood purification membrane of a blood purifier, characterized in that: The blood circuit and the dialysate circuit include a 1 st flow path for allowing a dialysate to flow from the dialysate circuit into the blood circuit via a connection flow path that bypasses the blood purifier to connect the dialysate circuit and the blood circuit, and a2 nd flow path for allowing the dialysate to flow from the dialysate circuit into the blood circuit via the blood purification membrane; The blood circuit described above includes a1 st pump, The dialysate circuit includes a2 nd pump and a1 st valve, The above-mentioned connecting flow path includes a2 nd valve, The control device performs the following operations: Closing the 1 st valve, opening the 2 nd valve, rotating the 1 st pump 1 st, stopping the 2 nd pump 2 nd rotation, and controlling the dialysate to flow through one of the 1 st channel and the 2 nd channel to return the blood in the blood circuit to the body; Determining whether the flow rate of the dialysate has reached a predetermined flow rate, and And controlling the pump 2 to stop the pump 1 from rotating, and controlling the pump 2 to rotate, in response to the determination that the flow rate of the dialysate reaches the predetermined flow rate, by opening the valve 1, closing the valve 2, and returning the blood in the blood circuit to the body by flowing the dialysate through the other one of the flow path 1 and the flow path 2.
2. 2. The blood purification apparatus according to claim 1, further comprising: a dialysate supply part for supplying the dialysate to the dialysate circuit, and A dialysate filter for storing the dialysate supplied from the dialysate supply unit; The control device controls the dialysate supply unit to flow the dialysate stored in the dialysate filter through one of the 1 st flow path and the 2 nd flow path in a state where the dialysate is not supplied to the dialysate circuit, and the dialysate returns blood in the blood circuit to the body.
3. 3. The blood purification apparatus according to claim 1 or 2, wherein the 1 st channel further includes a channel through which the dialysate flows from the dialysate circuit into the blood removal side circuit and the blood return side circuit via the connection channel; the 2 nd channel further includes a channel through which the dialysate flows from the dialysate circuit into the blood return side circuit.
4. 4. The blood purification apparatus according to claim 1 or 2, wherein the 1 st channel further includes a channel through which the dialysate flows from the dialysate circuit into the blood return side circuit and the blood removal side circuit via the connection channel; the 2 nd channel further includes a channel through which the dialysate flows from the dialysate circuit into the blood removing side circuit.
5. 5. The blood purification apparatus according to claim 1 or 2, wherein the 1 st channel further includes a channel through which the dialysate flows from the dialysate circuit into the blood removal side circuit and the blood return side circuit via the connection channel; the blood circuit and the dialysate circuit further include a 3 rd channel, and the 3 rd channel allows the dialysate to flow from the dialysate circuit, bypass the blood purifier, and flow into the blood return circuit and the blood removal circuit through the connection channel; The control device performs the following operations: controlling the dialysate to flow through one of the 1 st channel and the 3 rd channel, thereby returning the blood in the blood circuit to the body; determining whether the flow rate of the dialysate reaches a predetermined second flow rate, and And controlling the blood in the blood circuit to return to the body by flowing the dialysate in the other of the 1 st flow path and the 3 rd flow path in response to the determination that the flow rate of the dialysate reaches the predetermined second flow rate.
6. 6. The blood purification apparatus according to claim 1 or 2, wherein the 2 nd channel further includes a channel through which the dialysate flows from the dialysate circuit into a blood return side circuit; The blood circuit and the dialysate circuit further include a4 th channel through which the dialysate flows from the dialysate circuit to the blood removal circuit via the blood purification membrane; The control device performs the following operations: Controlling the dialysate to flow through one of the 2 nd channel and the 4 th channel, thereby returning the blood in the blood circuit to the body; Determining whether the flow rate of the dialysate reaches a predetermined third flow rate, and And controlling the blood in the blood circuit to return to the body by flowing the dialysate through the other one of the 2 nd channel and the 4 th channel in response to the determination that the flow rate of the dialysate reaches the predetermined third flow rate.
7. 7. The blood purification apparatus according to claim 1 or 2, wherein the control device selects one of the 1 st channel and the 2 nd channel as the channel of the dialysate in accordance with the treatment mode in order to return the blood in the blood circuit to the body after the blood purification treatment in the predetermined treatment mode.
8. 8. The blood purification apparatus of claim 7, wherein said control means performs the following operations: In the case where the above-described treatment pattern indicates a hemofiltration treatment or a hemodiafiltration treatment, Controlling to select the 2 nd channel as the channel of the dialysate, and returning the blood in the blood circuit to the body by flowing the dialysate through the 2 nd channel, and And controlling the blood in the blood circuit to return to the body by flowing the dialysate through the 1 st flow path in response to the determination that the flow rate of the dialysate reaches the predetermined flow rate.
9. 9. A blood purification device comprising a blood circuit, a dialysate circuit, and a control device, wherein liquid can flow through a blood purification membrane of a blood purifier, characterized in that: The blood circuit and the dialysate circuit include a 1 st flow path for allowing a dialysate to flow from the dialysate circuit into the blood circuit via a connection flow path that bypasses the blood purifier to connect the dialysate circuit and the blood circuit, and a 2 nd flow path for allowing the dialysate to flow from the dialysate circuit into the blood circuit via the blood purification membrane; The blood circuit described above includes a1 st pump, The dialysate circuit includes a2 nd pump and a1 st valve, The above-mentioned connecting flow path includes a2 nd valve, The control device performs the following operations: Closing the 1 st valve, opening the 2 nd valve, rotating the 1 st pump 1 st, stopping the 2 nd pump 2 nd rotation, and controlling the dialysate to flow through one of the 1 st channel and the 2 nd channel to return the blood in the blood circuit to the body; Determining whether the blood return flow has reached a predetermined blood return flow, and And controlling the 1 st valve to be opened, the 2 nd valve to be closed, the 1 st pump to stop the 1 st rotation, the 2 nd pump to perform the 2 nd rotation, and the dialysate to flow through the other one of the 1 st flow path and the 2 nd flow path to return the blood in the blood circuit to the body in response to the determination that the blood return amount of the blood reaches the predetermined blood return amount.
10. 10. A method for controlling a blood purification apparatus including a blood circuit, a dialysate circuit, and a control device, wherein liquid can flow through a blood purification membrane of a blood purifier, characterized in that: The blood circuit and the dialysate circuit include a1 st flow path and a2 nd flow path, the 1 st flow path allowing a dialysate to flow from the dialysate circuit into the blood circuit via a connection flow path that bypasses the blood purifier to connect the dialysate circuit and the blood circuit, and the 2 nd flow path allowing the dialysate to flow from the dialysate circuit into the blood circuit via the blood purification membrane; the blood circuit described above comprises a pump, The control device performs the following steps, including: A step of controlling the blood in the blood circuit by rotating the pump and causing the dialysate to flow through one of the 1 st channel and the 2 nd channel, and returning the blood to the exsanguination side or the blood return side; determining whether the flow rate of the dialysate reaches a predetermined flow rate, and And stopping rotation of the pump in response to the determination that the flow rate of the dialysate has reached the predetermined flow rate, and controlling the flow of the dialysate in the other of the 1 st flow path and the 2 nd flow path to return the blood in the blood circuit to the blood removing side or the blood returning side.
11. 11. A method for controlling a blood purification apparatus including a blood circuit, a dialysate circuit, and a control device, wherein liquid can flow through a blood purification membrane of a blood purifier, characterized in that: The blood circuit and the dialysate circuit include a1 st flow path and a2 nd flow path, the 1 st flow path allowing the dialysate to flow from the dialysate circuit into the blood circuit via a connection flow path connecting the dialysate circuit and the blood circuit by bypassing the blood purifier, and the 2 nd flow path allowing the dialysate to flow from the dialysate circuit into the blood circuit via the blood purification membrane; the blood circuit described above comprises a pump, The control device performs the following steps, including: A step of controlling the blood in the blood circuit by rotating the pump and causing the dialysate to flow through one of the 1 st channel and the 2 nd channel, and returning the blood to the exsanguination side or the blood return side; a step of determining whether or not the blood return flow amount reaches a predetermined blood return amount, and And stopping the rotation of the pump in response to the determination that the blood return amount of the blood reaches the predetermined blood return amount, and controlling the blood in the blood circuit to return to the blood removal side or the blood return side by flowing the dialysate in the other of the 1 st flow path and the 2 nd flow path.

Description

Blood purifying device Technical Field The present disclosure relates to a blood purification device, and more particularly, to a blood purification device that returns blood in a blood circuit to the body. Background If kidneys, which are part of human internal organs, do not function normally (renal failure), excess water in the body is turned into urine, and the function of expelling unnecessary metabolites and the like in the body is not performed. In order to cope with renal failure, a dialysis apparatus is used for performing treatment (hemodialysis treatment, hereinafter referred to as dialysis treatment) for extracorporeal circulation of blood from a patient and filtration of metabolites and moisture in the blood by a blood purifier. The dialysis apparatus withdraws blood from a patient, introduces the blood into a blood purifier (blood flow path) through a blood circuit, introduces the dialysate into the blood purifier (dialysate flow path) through a dialysate circuit from a supply source of the dialysate, exchanges components such as metabolites and electrolytes between the blood and the dialysate through the blood purifier, purifies the blood, and returns the purified blood to the patient. Since blood remains in the blood circuit after blood is introduced into the blood circuit by dialysis treatment, an operation of returning the remaining blood into the body of the patient (return blood) is generally performed. As the blood returning method, there is known a method of introducing a dialysate (or physiological saline) into a blood circuit through a connection line (replenishing line) connecting the dialysate circuit and the blood circuit by bypassing a blood purifier, and pressing the blood in the blood circuit with the dialysate to return the blood to the body. This method is referred to as the first blood return step (fluid infusion method). On the other hand, there is also known a method in which a dialysate is introduced from a dialysate circuit into the blood circuit through a filter membrane of a blood purifier, and the dialysate is pressed against blood in the blood circuit to return the blood to the body. This method is called the second blood return step (reverse filtration method). Prior art literature Patent literature Patent document 1 JP-A2019-187789 Disclosure of Invention Patent document 1 discloses a technique of replenishing a liquid by reverse filtration and replenishing the liquid by using a replenishing line in accordance with the state of permeability of a filtration membrane of a blood purifier. However, the fluid replacement operation disclosed in patent document 1 is an operation of supplementing fluid by using a fluid replacement line in combination with the precondition of fluid replacement by reverse filtration. Therefore, the respective advantages of the liquid replacement by the reverse filtration and the liquid replacement by the liquid replacement line may not be effectively exhibited. The dialysis device according to an embodiment relates to a blood purification device including a blood circuit and a dialysate circuit in which liquid can flow through a blood purification membrane of a blood purifier, the blood circuit and the dialysate circuit including a 1 st flow path and a 2 nd flow path, the 1 st flow path allowing dialysate to flow from the dialysate circuit into the blood circuit through a connection flow path that bypasses the blood purifier to connect the dialysate circuit and the blood circuit, the 2 nd flow path allowing the dialysate to flow from the dialysate circuit into the blood circuit through the blood purification membrane, and a control device controlling to return the blood in the blood circuit to the body by flowing the dialysate in one of the 1 st flow path and the 2 nd flow path, determining whether or not the flow rate of the dialysate has reached a predetermined flow rate, and controlling to return the dialysate to the body by flowing the dialysate in the other one of the 1 st flow path and the 2 nd flow path in response to the determined that the dialysate has reached the predetermined flow rate. The dialysis apparatus according to another embodiment relates to a blood purification apparatus including a blood circuit and a dialysis liquid circuit in which liquid can flow through a blood purification membrane of a blood purifier, the blood circuit and the dialysis liquid circuit including a 1 st flow path and a2 nd flow path, the 1 st flow path allowing dialysis liquid to flow from the dialysis liquid circuit into the blood circuit through a connection flow path which bypasses the blood purifier to connect the dialysis liquid circuit and the blood circuit, and the 2 nd flow path allowing dialysis liquid to flow from the dialysis circuit into the blood circuit through the blood purification membrane, and a control device controlling to return blood in the blood circuit to the body by flowing the dialysis liquid in one of the 1 st flow path a