Search

CN-116322729-B - Polysaccharide-enriched extract of Conus ellipticus

CN116322729BCN 116322729 BCN116322729 BCN 116322729BCN-116322729-B

Abstract

The present invention relates to an extract from flowers of kapok, preferably from the calyx of kapok, a process for preparing the same, and an extract obtained by the process. The invention also relates to a composition comprising said extract, advantageously a cosmetic, pharmaceutical or dermatological composition. The invention also relates to said composition or said extract for use in the prevention or treatment of diseases or pathological conditions of the skin, mucous membranes or hair and nails, and imbalances or diseases associated with imbalances in the microbiota of the skin, mucous membranes, hair, nails and related skin appendages. Finally, the present invention relates to a cosmetic care method for the skin, hair and nails or mucous membranes to improve the condition or appearance thereof, said method comprising the application of said composition or said extract.

Inventors

  • LECLERE-BIENFAIT SOPHIE
  • BREDIF STEPHANIE

Assignees

  • 科学发展实验室

Dates

Publication Date
20260512
Application Date
20210726
Priority Date
20200724

Claims (6)

  1. 1. A polysaccharide enriched extract from flowers of samara scolymus Bombax costatum comprising at least 15% of a polysaccharide having an apparent molecular weight of 1500 to 6000 kilodaltons relative to the total weight of the dry extract, the polysaccharide comprising 10 to 16% galactose, 10 to 17% rhamnose, 10 to 17% galacturonic acid and 3 to 7% glucuronic acid, wherein the extract comprises less than 1% polyphenols by weight relative to the total weight of the dry extract, and wherein the extract is obtained by a preparation process comprising at least one solid/liquid extraction step in water; wherein the preparation method comprising at least one solid/liquid extraction step in water comprises the steps of: Crushing the cotton of kapok, extracting the crushed cotton of kapok in water, separating the solid and liquid phases by decantation and/or centrifugation and/or precipitation and/or continuous filtration, and purifying and concentrating the obtained liquid phase by ultrafiltration and/or sterile filtration.
  2. 2. The extract of claim 1, comprising at least 30% by weight of polysaccharide relative to the total weight of the dry extract.
  3. 3. The extract according to claim 1, wherein the extract comprises 20% to 65% by weight of polysaccharide relative to the total weight of the dry extract.
  4. 4. A process for preparing a polysaccharide-rich extract from the flowers of kapok, comprising at least one solid/liquid extraction step in water, characterized in that it comprises the following successive steps: a) Crushing the flowers of the kapok of the costa; b) Extracting the crushed flowers in water; c) Separating the solid and liquid phases by decantation and/or centrifugation and/or precipitation and/or continuous filtration, and purifying and concentrating the resulting liquid phase by ultrafiltration and/or sterile filtration; d) Optionally, a step of bleaching the liquid phase with a suitable adjuvant; e) Optionally drying the extract obtained in step c) or d), and F) Optionally, the extract obtained in step c), d) or e) is made physically and microbiologically stable.
  5. 5. A composition comprising as active ingredient a polysaccharide-rich extract from flowers of kapok rib-fruit according to any one of claims 1 to 3 or an extract obtained by the process according to claim 4, and a suitable excipient.
  6. 6. Use of an extract according to any one of claims 1 to 3 or a composition according to claim 5 for the preparation of a composition for the prevention and/or treatment of the occurrence of bromhidrosis, acne and/or bacterial vaginosis.

Description

Polysaccharide-enriched extract of Conus ellipticus Technical Field The invention relates to a costa cotton (Bombax costatum) flower extract which is rich in polysaccharide. The invention also relates to a cosmetic, pharmaceutical or dermatological composition comprising such an extract. The invention also relates to a method for extracting a polysaccharide-rich extract of costa cotton, and to an extract obtainable by said method. The invention also relates to the use of the composition or the extract for preventing or treating diseases or pathological conditions of the skin, mucous membranes or skin appendages and for preventing or treating vascular diseases. Finally, the present invention relates to a method of care for the skin, skin appendages or mucous membranes to improve the condition or appearance thereof, said method comprising the application of the composition or the extract. Background Rib fruit cotton The Conus ellipticus belongs to the family kapok (FAMILLEDE BOMBACACEAE) (APG: malvaceae (Malvaceae)). The kapok is also known as Bombax andrieui or Bombax houardii. The rib-kapok is more commonly referred to as safflower kapok tree, cheese tree, red kapok tree, false kapok tree, forest kapok tree, voaka (Mo Leiyu), or Boumbou (Zhu Layu). Kapok (Bombax) is a pantotron comprising 8 species, 2 in africa, 5 in asia, 1 in oceangoin, as far as the solomoseal island. In the past, kapok has been a much broader demarcation. The rib cottons are sometimes considered to be homologous to Bombax buonopozense. Application of costate kapok In general, in Africa, confucius arvensis is a fairly common edible tree in which the leaves are dried and eaten like the leaves of a monkey tree, and flowers, especially the calyx, are also eaten. In buchner, bark is used to stain red teeth. Flowers are typically harvested for fleshy calyx, which is cooked and eaten as vegetables. The leaves are also consumed as vegetables. Immature fruits, and sometimes flowers, are added as a thickener in the sauce. Young immature fruits are also used for making beverages. The seed oil is edible. Flowers are highly valued as nectar flowers. Multiple parts of the tree are used in traditional medicine to treat different diseases. The ground root macerate is consumed in sauce or used as a bath for treating epilepsy. Bark preparations are applied to wounds to promote healing. In saintgaol and saintfreon, the diuretic properties are attributed to the stems and root bark. Bark is also used in the preparation of medicaments for the treatment of trichomoniasis, amebiasis and other forms of diarrhea. Bathing in the bark extract is used for treating mental disorder. The powdered bark is used in pharmaceutical compositions as a fumigant for treating headache. For the treatment of headache or toothache, bark compresses may be placed on the head. The leaves are used with other medicinal plants for the treatment of leucorrhea and diarrhea. The extract of crushed leaves is used as a drink to solve the problem during childbirth. Bathing repeatedly in the crushed leaf extract to treat convulsion. The dry leaf tea is taken or smeared to treat measles. In case of severe swelling, the decoction of the leaf, stem or root bark is taken as a drink. The decoction of leaves and twigs is administered to treat jaundice. The leaf decoction is also administered to children for treating rickets. Different parts of the plant are used to promote lactation and as an anti-fatigue supplement. The skin is rubbed with leaves mixed with shea butter to treat leprosy. In Marie, decoction of bark, leaves and other plant parts is taken to treat menstrual disorder. The leaves have skin caring effect, and the warm water bath of the leaf decoction can be used for fever patients, especially children. Leaves are also used to treat hookworms and flowers are used to treat tapeworms. All of this data is from ethnic botanic reports written by doctor at water and forest university Lassina SANOU. He worked in the buchnafasso national tree species Center (CNRS) environment and sustainable development department located in dado (12 months 2014). Polysaccharide Polyglycoside or polysaccharide or glycan is arbitrarily defined as a high molecular weight polymer resulting from the condensation of a large number of sugars (d' oses) or sugars (sucres). They are involved in different aspects of plant life or even survival. For example, they are responsible for the rigidity of the higher plant cell walls (cellulose, hemicellulose, lignin.) they are forms of energy storage (starch) that can protect tissues against dehydration due to their hydrophilicity. We divide into: Homogeneous polysaccharide (condensation of the same sugar), and Heterogeneous polysaccharides (hexoses, pentoses, glycoethers), The two categories may be linear or branched. Microbiota (MICROBIOTE) and microbiome (MICROBIOME) The skin microbiota is all microorganisms (bacteria, viruses, fungi) present on and in the skin. Microbiota are