CN-116392668-B - Insulin pump injection two-stage slow-release control method

Abstract

The two-stage slow-release control method for the insulin pump injection comprises the following steps of firstly, attaching an injection end of a two-stage slow-release insulin applying pump to human skin in a designated area, secondly, collecting blood sugar concentration and body temperature data of a human body in real time by a detection mechanism, thirdly, starting the insulin pump, pumping the insulin medicine into a shell according to the injection amount and speed set by a manual doctor's advice, fourthly, realizing flow control of the insulin medicine by a control circuit module, a piezoelectric ceramic mechanism and a flow control mechanism, fifthly, injecting the insulin medicine into the skin of the human body from top to bottom by an injection mechanism, sixthly, completely injecting the insulin medicine, and removing the two-stage slow-release insulin applying pump. The invention can monitor the blood sugar concentration and the body temperature of the human body in real time, provides technical guarantee for safe injection, can realize two-stage slow release of insulin liquid medicine, can realize regional control of the injection of the insulin liquid medicine according to the needs, and prevents the occurrence of emergency.

Inventors

• WANG YONGXIN
• WANG LEIJIE
• ZHANG LONG
• ZHANG DANDAN
• CHEN WEIWEN
• DING LEI
• Ming wuyi

Assignees

• 深圳瑞宇医疗科技有限公司

Dates

Publication Date

20260508

Application Date

20230421

Claims (3)

1. 1. The insulin pump injection two-stage slow release control device is characterized by comprising a shell, an insulin pump, a detection mechanism, a plurality of piezoelectric ceramic mechanisms, a plurality of flow regulation mechanisms, an injection mechanism and a control circuit module; The insulin pump is arranged in the outer area of the top center of the shell and is connected with the insulin pump through the conduit assembly, the detection mechanism is arranged around the bottom of the shell, the inner cavity of the shell is uniformly divided into a plurality of injection cavities which are circumferentially arrayed around the vertical center line of the injection cavities through a plurality of vertical partition boards, each piezoelectric ceramic mechanism is uniformly distributed on the top of the shell and corresponds to each injection cavity one by one, each flow regulating mechanism is correspondingly arranged in each injection cavity, each piezoelectric ceramic mechanism is correspondingly extruded and acts on each flow regulating mechanism, the injection mechanisms are uniformly arranged at the bottom of the shell and are communicated with each injection cavity, insulin liquid medicine is pumped into the upper parts of the corresponding flow regulating mechanisms in each injection cavity through the conduit assembly by the insulin pump, the control circuit module is arranged in a host of the insulin pump, a button, a display screen and an alarm which are in signal connection with the control circuit module are arranged on the shell of the insulin pump, and each piezoelectric ceramic mechanism is in signal connection with the control circuit module; The shell comprises a rectangular box body which is transparent up and down, an upper cover plate is arranged at the upper end of the rectangular box body in a sealing way, a bottom cover plate is arranged at the lower end of the rectangular box body in a sealing way, and each vertical partition plate is fixedly arranged in the rectangular box body to uniformly divide the inner cavity of the rectangular box body into each injection cavity; The insulin pump is fixedly arranged at the top center of the upper cover plate, the upper cover plate is provided with extrusion holes which are penetrated up and down at the middle positions corresponding to the injection cavities, the size of the extrusion holes is 1/4-1/2 of the size of the cross section of the corresponding injection cavity, and each piezoelectric ceramic mechanism is fixedly arranged in each extrusion hole correspondingly; the detection mechanism comprises four long micro-needles which are vertically arranged at four corners of the bottom cover plate respectively, a blood sugar concentration sensor and a body temperature sensor are arranged in the long micro-needles, and signal wires of the blood sugar concentration sensor and the body temperature sensor are led out of the bottom cover plate and are connected with the control circuit module through first sensor wires in a signal manner; Each piezoelectric ceramic mechanism has the same structure, each piezoelectric ceramic mechanism comprises an outer cover with an opening at the lower side, a sealing flexible diaphragm and piezoelectric ceramics, the lower port of the outer cover is in vertical correspondence with the corresponding extrusion hole and is matched with the corresponding extrusion hole in size and shape, the outer cover is covered right above the corresponding extrusion hole, an annular flange end plate is arranged on the periphery of the outer side of the lower end edge of the outer cover, the outer cover is fixedly connected to the upper cover plate through the annular flange end plate, the sealing flexible diaphragm is fixedly connected in the corresponding extrusion hole and seals the corresponding extrusion hole, the piezoelectric ceramics are matched with the corresponding extrusion hole in size and shape, the piezoelectric ceramics are arranged in cavities surrounded by the sealing flexible diaphragm and the outer cover and are correspondingly matched and embedded in the corresponding extrusion hole, the top of the piezoelectric ceramics is in pressing contact with the inner top surface of the outer cover, the bottom of the piezoelectric ceramics is pressed on the upper surface of the sealing flexible diaphragm, the lower surface of the sealing flexible diaphragm is flush with the inner surface of the upper cover plate, and an electric control wire of the piezoelectric ceramics is led out of the outer cover and is in signal connection with a control circuit module; The catheter assembly comprises a plurality of branch catheters, the branch catheters are respectively arranged in one-to-one correspondence with the injection cavities, the liquid inlet ends of the branch catheters are led into the insulin pump and are connected with an insulin medicine bottle arranged in the insulin pump, the liquid outlet ends of the branch catheters respectively penetrate through the upper cover plate to be led into the injection cavities respectively corresponding to the positions of the injection cavities and respectively guide the upper parts of the corresponding microporous elastic pads, the outer sleeve is wrapped outside a section of the branch catheters between the insulin pump and the upper cover plate, the liquid medicine flow sensors are respectively arranged on the branch catheters, and the liquid medicine flow sensors are respectively connected with the control circuit module through second sensor wires in a signal manner; The injection mechanism comprises a plurality of short micro-needles which are uniformly distributed on the lower surface of the bottom cover plate in an array mode and vertically correspond to the injection cavities, and the upper ends of the short micro-needles upwards penetrate through the bottom cover plate and are communicated with the injection cavities.
2. 2. The insulin pump injection two-stage slow release control device according to claim 1, wherein each flow control mechanism has the same structure and comprises a microporous elastic pad and a multi-layer slow release pad, the microporous elastic pad and the multi-layer slow release pad are overlapped up and down and are matched and arranged in corresponding injection cavities, the microporous elastic pad and the multi-layer slow release pad are in clearance fit with the corresponding injection cavities, the top surface of the microporous elastic pad is in pressure connection with the inner surface of an upper cover plate, the bottom surface of the multi-layer slow release pad is in pressure connection with the inner surface of a bottom cover plate, the lower surface of a sealing flexible diaphragm is in pressure connection with the middle part of the top surface of the microporous elastic pad, and the multi-layer slow release pad is formed by three layers of multi-cavity compressible extrusion materials.
3. 3. The insulin pump injection two-stage slow release control device according to claim 2, wherein each liquid medicine flow sensor detects the insulin liquid medicine flow in each branch conduit in real time and transmits detected information to the control circuit module through corresponding sensor wires, the control circuit module controls the expansion and contraction amount of each corresponding piezoelectric ceramic according to the insulin liquid medicine flow detected by each liquid medicine flow sensor in real time in two modes, and the micropore gap distribution condition of each corresponding micropore elastic pad is changed, so that the control of the injection flow of the insulin liquid medicine in each corresponding injection cavity is realized, wherein the two modes are as follows: (I) Anomaly detection and handling When a certain liquid medicine flow sensor detects that the insulin liquid medicine flow in a corresponding branch conduit is 30% or more higher than the expected injection speed, the control circuit module judges that the application of the area where the injection cavity connected with the corresponding branch conduit is located is abnormal, namely, each short microneedle below the area is not worn correctly, the situation of insulin leakage liquid medicine occurs, the control circuit module controls the piezoelectric ceramic above the area to electrostrict and stretch up and down rapidly through a corresponding electric control wire, the lower part of the piezoelectric ceramic downwards presses a sealing flexible diaphragm below the piezoelectric ceramic and downwards protrudes into a corresponding injection cavity through a corresponding pressing hole, and then the corresponding microporous elastic pad is pressed, so that the micropore gap distribution situation of the microporous elastic pad is changed, and meanwhile, the microporous elastic pad presses a plurality of layers of slow release pads below the microporous elastic pad, so that insulin liquid medicine in the injection cavity of the area cannot flow out; (II) the insulin liquid medicine flow rates of the corresponding areas of the injection cavities are dynamically kept balanced When each liquid medicine flow sensor detects that the insulin liquid medicine flow in each corresponding branch duct is inconsistent, the control circuit module dynamically adjusts the up-down expansion amount and the regulation period of each piezoelectric ceramic according to the current injection speed and the current flow deviation thereof by adopting a fuzzy control strategy, so as to dynamically squeeze each microporous elastic pad, change the micropore gap distribution condition of each microporous elastic pad, and simultaneously, each microporous elastic pad respectively squeezes the multilayer slow-release pad below the microporous elastic pad, thereby realizing the dynamic control of the insulin liquid medicine flow in each injection cavity and dynamically keeping the insulin liquid medicine flow in each branch duct balanced.

Description

Insulin pump injection two-stage slow-release control method Technical Field The invention relates to the technical field of insulin injection pumps, in particular to a two-stage slow release control method for insulin pump injection. Background For diabetics, the blood of the diabetics is in a hyperglycemia environment for a long time, so that a plurality of complications are caused, and serious damage is caused to the body. Therefore, controlling blood glucose concentration is critical. Insulin injection is the most effective method of controlling blood glucose concentration. Today, various insulin pumps have been applied to insulin injections instead of manual injections. The existing piezoelectric pump system uses an electric drive signal to act on a piezoelectric vibrator to generate vibration, so that the piezoelectric vibrator vibrates up and down in a pump cavity to cause the change of the volume in the pump cavity so as to cause a certain change of the output dosage of insulin. In the conventional injection method, when an injector with one needle is used for insulin treatment, the condition of needle breakage often occurs, in addition, when insulin is injected, an injection area is carefully selected, the injection area is firstly marked on the abdomen before the insulin is injected, the point of the last injection is avoided as much as possible, 75% medical alcohol is used for spiral disinfection from the injection center point to the periphery, the disinfection straight line is generally larger than 5cm, the injection position needs to be periodically rotated, the same position is not repeatedly injected, hard lumps are easy to grow, and insulin absorption is influenced. In order to solve the technical problems, we provide a two-stage slow release control method for insulin pump injection. Disclosure of Invention The invention aims to provide a two-stage slow release control method for insulin pump injection, which can monitor the blood sugar concentration and the body temperature of a human body in real time, provides technical support for safe injection, can realize two-stage slow release of insulin liquid medicine through an insulin pump, a piezoelectric ceramic mechanism, a microporous elastic pad and a multi-layer slow release pad, can realize regional control of the injection of the insulin liquid medicine according to requirements, and prevents emergency. In order to achieve the above purpose, the invention adopts the following technical scheme: The insulin pump injection two-stage slow release control method specifically comprises the following steps: Firstly, an injection end of a two-stage slow-release insulin applying pump is applied to human skin in a designated area, and the two-stage slow-release insulin applying pump comprises a shell, an insulin pump, a detection mechanism, a plurality of piezoelectric ceramic mechanisms, a plurality of flow regulating mechanisms, an injection mechanism and a control circuit module; Secondly, the detection mechanism collects blood sugar concentration and body temperature data of a human body in real time and stores the blood sugar concentration and body temperature data into the control circuit module according to a set period; Starting an insulin pump, and pumping the insulin medicine into the shell according to the injection dosage and the injection speed set by the manual doctor's advice; Fourthly, regulating the expansion and contraction amount of each piezoelectric ceramic mechanism through a control circuit module, and realizing the flow control of insulin liquid medicine by extrusion action of each piezoelectric ceramic mechanism through each corresponding flow regulating mechanism; Fifthly, insulin liquid medicine is injected into the skin of a human body through an injection mechanism after passing through corresponding flow regulating mechanisms from top to bottom; And sixthly, after the insulin medicine liquid is injected, the two-stage slow-release insulin applying pump is removed. The insulin pump sets up in the outside region at the top center of casing and realizes the connection of both through pipe subassembly, detection mechanism sets up around the bottom of casing, the inner chamber of casing evenly separates into a plurality of injection chamber of circumference array around its vertical central line through a plurality of vertical baffles, each piezoceramics mechanism equipartition is at the top of casing and correspond from top to bottom with each injection chamber one by one respectively, each flow control mechanism corresponds the setting respectively in each injection chamber, each piezoceramics mechanism corresponds the extrusion respectively and acts on each flow control mechanism, injection mechanism evenly sets up in the bottom of casing and communicates with each injection chamber, the insulin pump pumps insulin liquid medicine into each corresponding flow control mechanism upper portion in each injection chamber res