CN-116491968-B - Side branch circulation index value determining method based on single-phase CTA

CN116491968BCN 116491968 BCN116491968 BCN 116491968BCN-116491968-B

Abstract

The invention discloses a single-phase CTA-based collateral circulation index value determining method which comprises the steps of obtaining single-phase CTA images and DWI images, preprocessing the images to obtain first images of different layers, registering the first images of different layers and identifying blood supply brain tissue areas to obtain second images of different layers, identifying an ischemic range as a blood vessel aggregation range according to the DWI images, mapping the blood vessel aggregation range to the second images of different layers to obtain third images of different layers, calculating the third images of different layers to obtain the ratio of the area of the blood vessel aggregation range to the area of the healthy side blood vessel ring range, calculating the average value according to the ratio and the number of the third images, and determining the average value as the collateral circulation index value of the single-phase CTA images to obtain visual and accurate assessment results. Can be applied to the field of acute ischemic stroke collateral circulation evaluation based on single-phase CTA.

Inventors

YANG YUNQIU
HU QINGMAO
WANG ZHEN
LIU LIBO
YANG CHEN

Assignees

珠海中科先进技术研究院有限公司
中国科学院深圳先进技术研究院

Dates

Publication Date: 20260505
Application Date: 20230309

Claims (8)

1. A side branch circulation index value determining method based on single-phase CTA is characterized by comprising the following steps: acquiring a single-phase CTA image and a DWI image; preprocessing the single-phase CTA image to obtain first images of different layers, wherein the first images of different layers are characterized by images of the single-phase CTA image projected at different distances in the direction of a coronal plane; registering the first images of different layers based on preset brain template images respectively, and identifying blood supply brain tissue areas to obtain second images of different layers; Recognizing according to the DWI image to obtain an ischemic range as a blood vessel aggregation range, and mapping the blood vessel aggregation range to the second images of different layers to obtain third images of different layers; Calculating the third images of different layers to obtain the ratio of the area of the blood vessel aggregation circle range to the area of the blood vessel circle range on the healthy side; and calculating and processing according to the ratio and the number of the third images to obtain a mean value, and determining the mean value as a collateral circulation index value of the single-phase CTA image.
2. The method for determining the side branch circulation index value based on single-phase CTA according to claim 1, wherein preprocessing the single-phase CTA image to obtain first images of different levels comprises: projecting the single-phase CTA image in the direction of the coronal plane to obtain a projection image; intersecting different horizontal lines with contour lines in the projection graph to obtain intersection points; Acquiring two intersection points of the same horizontal line and the contour line, and calculating the intersection point distance of the two intersection points; Comparing the intersection point distances corresponding to different horizontal lines, and selecting the horizontal line corresponding to the intersection point distance with the smallest value as a target horizontal line; And removing the image below the target horizontal line in the projection graph to obtain a first image.
3. The method for determining the collateral circulation index value based on single-phase CTA according to claim 1, wherein the registering the first images of different levels based on the preset brain template image and identifying the blood supply brain tissue region to obtain the second images of different levels respectively comprises: computing rigid transformation values of the brain template image and the first image: the second image is obtained by applying the rigid transformation values to a brain mask of the brain template.
4. The method for determining the collateral circulation index value based on single-phase CTA according to claim 3, wherein the registering the first images of different levels based on the preset brain template image and identifying the blood supply brain tissue region to obtain the second images of different levels respectively comprises: and removing the skull image in the second image through a neural network.
5. The method for determining a collateral circulation index value based on single-phase CTA according to claim 1, wherein the registering the first images of different levels based on preset brain template images and identifying blood supply brain tissue areas to obtain second images of different levels respectively further comprises: And filtering the second image in different scales.
6. A processing apparatus for single-phase CTA image data, comprising: the first module is used for acquiring a single-phase CTA image and a DWI image; the second module is used for preprocessing the single-phase CTA image to obtain first images of different layers, wherein the first images of different layers are characterized by images of projecting the single-phase CTA image at different distances in the direction of a coronal plane; the third module is used for registering the first images of different layers based on preset brain template images and identifying blood supply brain tissue areas to obtain second images of different layers; a fourth module, configured to identify an ischemic range as a blood vessel aggregation range according to the DWI image, and map the blood vessel aggregation range to the second images of different layers to obtain third images of different layers; A fifth module, configured to calculate the third images of different aspects to obtain a ratio of an area of the blood vessel aggregation circle range to an area of the blood vessel health circle range; and a sixth module, configured to calculate and process the ratio and the number of the third images to obtain a mean value, and determine the mean value as a side branch circulation index value of the single-phase CTA image.
7. An electronic device comprising a processor and a memory; The memory being for storing a program, the processor executing the program to implement the method of any one of claims 1 to 5.
8. A computer-readable storage medium, characterized in that the storage medium stores a program that is executed by a processor to implement the method of any one of claims 1 to 5.

Description

Side branch circulation index value determining method based on single-phase CTA Technical Field The invention relates to the field of collateral circulation assessment based on single-phase CTA, in particular to a collateral circulation index value determining method based on single-phase CTA. Background At present, more and more importance is attached to the evaluation of CTA images on the side branch circulation of acute ischemic stroke, but the rapid evaluation and interpretation of the side branch circulation of acute ischemic stroke based on single-phase CTA is always a big problem, because the images are complex, and particularly for the evaluators with low annual cost, more time is often required for understanding. The evaluation of the collateral circulation of the acute ischemic stroke based on single-phase CTA is not accurate at present. Disclosure of Invention In view of the above, the embodiment of the invention provides a method for determining a side branch circulation index value based on single-phase CTA. To obtain visual and more accurate evaluation results of acute ischemic stroke collateral circulation based on single-phase CTA. The invention provides a side branch circulation index value determining method based on single-phase CTA, which comprises the steps of obtaining single-phase CTA images and DWI images, preprocessing the single-phase CTA images to obtain first images of different layers, wherein the first images of different layers are characterized by being images projected on the single-phase CTA images at different distances in the coronal direction, registering the first images of different layers respectively based on preset brain template images, identifying blood supply brain tissue areas to obtain second images of different layers, identifying ischemia range according to the DWI images to obtain blood vessel aggregation ranges, mapping the blood vessel aggregation ranges to the second images of different layers to obtain third images of different layers, calculating the ratio of the area of the blood vessel aggregation range to the area of a healthy side blood vessel range of the third images of different layers respectively, calculating the average value according to the ratio and the number of the third images, and determining the average value as the side branch circulation index value of the single-phase CTA. According to some embodiments of the invention, the preprocessing of the single-phase CTA image to obtain first images of different layers comprises the steps of projecting the single-phase CTA image in the direction of a coronal plane to obtain a projection image, intersecting different horizontal lines with a contour line in the projection image to obtain intersection points, obtaining two intersection points of the same horizontal line and the contour line, calculating the intersection point distance of the two intersection points, comparing the intersection point distances corresponding to the different horizontal lines, selecting a horizontal line corresponding to the intersection point distance with the smallest value as a target horizontal line, and removing the image below the target horizontal line in the projection image to obtain the first image. According to some embodiments of the invention, registering the first images of different levels and identifying areas of blood supply brain tissue to obtain second images of different levels based on preset brain template images respectively comprises calculating rigid transformation values of the brain template images and the first images, wherein the rigid transformation values are applied to brain masks of the brain template to obtain the second images through rigid transformation. According to some embodiments of the invention, registering the first images of different levels based on preset brain template images and identifying blood supply brain tissue regions to obtain second images of different levels comprises removing skull images in the second images through a neural network. According to some embodiments of the invention, the registering the first images of different levels based on the preset brain template images respectively and identifying blood supply brain tissue areas to obtain second images of different levels further comprises filtering the second images of different scales. The invention provides an acute ischemic stroke collateral circulation assessment device based on single-phase CTA, which comprises a first module, a second module, a fifth module, a sixth module and a third module, wherein the first module is used for acquiring single-phase CTA images and DWI images, the second module is used for preprocessing the single-phase CTA images to obtain first images of different layers, the first images of different layers are characterized by being projected on the single-phase CTA images at different distances in the coronal direction, the third module is used for respectively registerin