CN-116615141-B - Photoacoustic diagnostic apparatus and method

Abstract

The present invention relates to a photoacoustic diagnostic apparatus and a photoacoustic diagnostic method for measuring blood glucose in blood by measuring a morphological change of a membrane by an acoustic wave, and more particularly, to a photoacoustic diagnostic apparatus and a photoacoustic diagnostic method for adjusting the frequency response of a diagnostic apparatus by adjusting the size of a membrane. The photoacoustic diagnostic apparatus according to an embodiment of the present invention includes a light source that irradiates light to a subject to emit sound, a plurality of sound pickup units each including a film whose shape changes due to the sound, and a measuring unit that measures the shape change of the film, wherein the films of the plurality of sound pickup units may have different sizes.

Inventors

• KANG YUNHAO

Assignees

• HME方正有限公司

Dates

Publication Date

20260505

Application Date

20211104

Priority Date

20201106

Claims (3)

1. 1. A photoacoustic diagnostic apparatus comprising: A light source that irradiates light to an object to be inspected and emits sound; A plurality of sound pickup units each having a film whose shape changes due to the sound, and A measuring unit for measuring a change in the form of the film, The films of the plurality of sound pickup portions have mutually different sizes, Wherein each resonance frequency of the film of the sound pickup portion matches a photoacoustic peak of blood sugar, Wherein each resonance frequency of the film of the sound pickup portion is matched by selecting a desired number of peaks among main peaks detected when laser light is irradiated to blood.
2. 2. A photoacoustic diagnostic method for measuring blood glucose using a photoacoustic diagnostic apparatus, the photoacoustic diagnostic method comprising: Irradiating light to the object by using a light source; a plurality of sound pickup units each including a film for picking up sounds emitted from the subject; Determining a morphological change of the membrane; Analyzing the presence and amount of blood sugar contained in blood by analyzing the morphological change of the film, and matching each resonance frequency of the film of the sound pickup portion with a photoacoustic peak of blood sugar by adjusting the size of the film of the sound pickup portion, Wherein each resonance frequency of the film of the sound pickup portion is matched by selecting a desired number of peaks among main peaks detected when laser light is irradiated to blood.
3. 3. A computer-readable recording medium having recorded thereon a program for implementing the method of claim 2.

Description

Photoacoustic diagnostic apparatus and method Technical Field The present invention relates to a photoacoustic diagnostic apparatus and a photoacoustic diagnostic method for measuring blood glucose in blood by measuring a morphological change of a membrane by an acoustic wave, and more particularly, to a photoacoustic diagnostic apparatus and a photoacoustic diagnostic method for adjusting a frequency response of a diagnostic apparatus by adjusting a size of a membrane. Background The photoacoustic diagnostic technique is a technique for non-invasively forming a living tissue by utilizing the photoacoustic effect. When a short electromagnetic pulse of laser light is incident on a living tissue for photoacoustic diagnosis, a part of energy is absorbed by the tissue and converted into heat, thereby causing instantaneous thermoelastic expansion. As a result, ultrasonic waves having a wide frequency band are emitted, and the ultrasonic waves are detected in a plurality of directions by the ultrasonic transducer, whereby the ultrasonic waves can be converted into images. Since the photoacoustic diagnostic technique converts electromagnetic waves into ultrasonic waves for detection, there is an advantage in that characteristics of optical imaging and ultrasonic imaging can be mixed. Although the contrast (contrast) of the pure optical imaging technique is much higher than that of the ultrasonic imaging, the ultrasonic imaging has a disadvantage that imaging is only performed from the surface of a living body to a specific depth because of high light scattering of soft tissue (soft tissue), and in contrast, the ultrasonic imaging has a high spatial resolution (spatial resolution) as that which can be used for fetal examination. Photoacoustic imaging utilizes ultrasonic wave conversion due to the photoacoustic effect to overcome the disadvantage of optical imaging, i.e., low imaging depth, so that high optical contrast and high spatial resolution can be achieved at the same time. A device for realizing photoacoustic diagnosis technology is generally composed of an optical unit for irradiating laser light and a transducer for measuring ultrasonic waves. Transducers for measuring ultrasonic waves include piezoelectric (piezo) type and microelectromechanical system (MEMS: micro Electro MECHANICAL SYSTEMS) type. In the piezoelectric system, the pressure caused by the ultrasonic wave causes a potential to be formed in the piezoelectric material, and the ultrasonic wave is measured by measuring a potential difference, that is, a voltage. Since the transducer is constituted by a module independent of the optical unit, the photoacoustic diagnostic apparatus having the transducer has a problem that it is difficult to reduce the size thereof, and the convenience of use is lowered. Disclosure of Invention In order to solve the above-mentioned problems, an object of the present invention is to provide a photoacoustic diagnostic apparatus and method that adjusts the resonant frequency of a transducer by adjusting the size of a film and matches a blood glucose photoacoustic peak (peak). By an embodiment of the present invention, a photoacoustic diagnostic apparatus is provided. The photoacoustic diagnostic apparatus according to an embodiment of the present invention includes a light source that irradiates light to a subject to emit sound, a plurality of sound pickup units each including a film whose shape changes due to the sound, and a measuring unit that measures the shape change of the film, wherein the films of the plurality of sound pickup units may have different sizes. In the photoacoustic diagnostic apparatus according to an embodiment of the present invention, each resonance frequency of the above-described sound pickup section may be matched with a photoacoustic peak (peak) of blood sugar. By an embodiment of the present invention, a photoacoustic diagnostic method is provided. The photoacoustic diagnostic method according to an embodiment of the present invention may include a light irradiation step of irradiating a subject with a light source, a sound pickup step of picking up sounds emitted from the subject by a plurality of sound pickup portions including films, a measurement step of measuring a change in the form of the films, and a blood glucose analysis step of analyzing the presence and amount of blood glucose contained in blood by analyzing the change in the form of the films. The photoacoustic diagnostic method according to an embodiment of the present invention may further include the step of matching each resonance frequency of the sound pickup portion with a photoacoustic peak (peak) of blood sugar by adjusting the size of the film of the sound pickup portion. By an embodiment of the present invention, a computer-readable recording medium having recorded thereon a program for implementing the above-described method can be provided. The photoacoustic diagnostic apparatus according to the present invention