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CN-116832735-B - Mesoscale flow reactor and construction method thereof

CN116832735BCN 116832735 BCN116832735 BCN 116832735BCN-116832735-B

Abstract

The invention discloses a mesoscale flow reactor and a construction method thereof, wherein the construction method comprises the following steps of carrying out hydrophilic treatment on the surface of a hydrophobic flexible substrate to form at least one hydrophilic area, and forming an aqueous solution containing nano particles on the surface of the hydrophilic area; removing moisture in the aqueous solution containing the nano particles so that the nano particles are deposited on the surface of the hydrophilic area to form a nano particle layer; after the nanoparticle layer surface is loaded with catalyst, the flexible substrate is rolled into a reaction channel to construct the mesoscale flow reactor. The reactor constructed by the invention has the characteristics of novel structure and controllable size, deposited nano particles can efficiently load the catalyst, the stability and the service life of the catalyst are functionally improved, the reactivity, the selectivity and the loading capacity of the catalyst can be increased, the use amount of the catalyst can be controlled, and the cost and the efficiency are reduced.

Inventors

  • ZHANG JING
  • YU CHAO
  • QIN YIPENG

Assignees

  • 南京宇源新能碳中和科技有限公司

Dates

Publication Date
20260512
Application Date
20230807

Claims (10)

  1. 1. A method of constructing a mesoscale flow reactor comprising the steps of: s1, carrying out hydrophilic treatment on the surface of a hydrophobic flexible substrate to form at least one hydrophilic area, and forming an aqueous solution containing nano particles on the surface of the hydrophilic area; s2, removing moisture in the aqueous solution containing the nano particles so that the nano particles are deposited on the surface of the hydrophilic area to form a nano particle layer; s3, after the surface of the nanoparticle layer is loaded with a catalyst, the flexible substrate is curled into a reaction channel, so that the mesoscale flow reactor is constructed.
  2. 2. The method of claim 1, wherein in the step S1, the hydrophobic flexible substrate comprises one or more of polytetrafluoroethylene, polytetrafluoroethylene-perfluoropropylene copolymer, polyether ether ketone, polyimide, perfluoroalkoxy resin, polydimethylsiloxane, hydrophobic flexible glass, aluminum plastic film, silicone plate, stainless steel, and hydrophobically treated metal substrate, wherein the metal substrate comprises titanium, magnesium, or copper.
  3. 3. The method according to claim 2, wherein the hydrophobically treated agent comprises an alkylated silane or a fluororesin in the hydrophobically treated metal substrate, wherein the alkylated silane comprises at least one of methyltrimethoxysilane, vinyltrimethoxysilane, cetyltrimethoxysilane chloride, methacryloxypropyl trimethoxysilane, and the fluororesin comprises at least one of perfluoroalkyl methacrylate and perfluoroalkyl acrylate.
  4. 4. The method according to claim 1, wherein in the step S1, the hydrophilic treatment of the surface of the hydrophobic flexible substrate forms at least one hydrophilic region, and the method comprises the step of performing an arrayed hydrophilic treatment on the surface of the hydrophobic flexible substrate to form a plurality of arrayed hydrophilic regions.
  5. 5. The method according to claim 1, wherein in the step S1, the nanoparticle comprises a nanoparticle which is not modified and/or modified by a chemical group, wherein the unmodified nanoparticle comprises one or more of silica, ferroferric oxide, carbon nanotube, ceria, gamma-alumina, titania, zinc oxide, polyethyleneimine, liquid crystal nanoparticle, dendritic polyamide-amine, polylactic acid, polyvinyl alcohol, and polyacrylamide, and the chemical group comprises at least one of amino group, carboxyl group, ethylenic bond, hydroxyl group, and mercapto group.
  6. 6. The method of claim 4, wherein the hydrophilic treatment comprises plasma treatment or ozone treatment on the surface of the hydrophobic flexible substrate or laser ablation oxidation treatment on a localized portion of the surface of the hydrophobic flexible substrate using a masking method.
  7. 7. The method according to claim 1, wherein in the step S3, the catalyst comprises at least one of a metal catalyst, a non-metal catalyst, a perovskite and an enzyme, wherein the metal catalyst comprises one or more of iron, cobalt, nickel, platinum, palladium, rhodium, zinc, manganese, copper, gold, silver and lead, the non-metal catalyst comprises one or more of carbon black, activated carbon, carbon nanotubes, silica, alumina and ferric oxide, the perovskite comprises at least one of an inorganic perovskite ABO 3 , a double perovskite structure or defect type perovskite A 2 BX 6 、A 2 B 1+ B 3+ X 6 、AB 2 X 7 、AB 3 X 10 and a perovskite-like A 3 B 2 X 9 , wherein A is an alkali metal, alkaline earth metal or rare earth element ion, B is a transition metal or a part of a main group metal element, X is at least one of F - 、I - 、Br - 、Cl - , and the enzyme comprises at least one of amylase, protease, lipase, phosphodiesterase, superoxide dismutase and glutamine synthetase.
  8. 8. The method according to claim 1, wherein in the step S3, the method of supporting the catalyst on the surface of the nanoparticle layer includes one or more of electrostatic adsorption, embedding blending, and covalent crosslinking.
  9. 9. The method according to claim 1, wherein after the flexible substrate is curled into the reaction channel in the step S3, the method further comprises bonding both ends of the flexible substrate with an adhesive to shape the reaction channel, wherein the adhesive comprises at least one of a silicone adhesive, a polyimide adhesive, a polyurethane adhesive, an acrylate adhesive, PDMS, a curing agent, a two-component polyurethane adhesive, and an epoxy adhesive.
  10. 10. A mesoscale flow reactor, characterized in that it is prepared by a construction method according to any one of claims 1-9.

Description

Mesoscale flow reactor and construction method thereof Technical Field The invention relates to the field of microreactors, in particular to a mesoscale flow reactor and a construction method thereof. Background The reactor is a device for realizing chemical process, can complete liquid phase single-phase reaction process and liquid-liquid, gas-liquid, liquid-solid, gas-liquid-solid and other multiphase reaction process, and has been widely applied in the fields of chemistry, pharmacy, energy sources and the like. The conventional reactor has the characteristics of simple structure and convenient operation, and is usually composed of a large-scale reaction vessel containing one or more catalysts, and reactants are subjected to chemical reaction under the catalysis to prepare corresponding products, wherein typical reaction vessels are a kettle type reactor and a tubular type reactor. In the reactor, the reaction process is often accompanied with a high-temperature strong exothermic effect, heat released by the reaction is easy to form heat accumulation in the catalyst bed, especially the catalyst is fed into an industrialized amplification stage, the catalyst loading is increased, the catalyst bed is thickened, a large amount of reaction heat cannot be timely discharged, the catalyst bed is rapidly heated, and the problems of difficult control of amplification reaction, increased byproducts and the like are caused. Therefore, the research on the efficient and safe reactor improves the availability of the catalyst, and the solution of the strong exothermic effect is particularly important for the development of the reactor process. With the continuous development of micro-nano processing technology, the study of micro-reactors is gradually hot. The micro reactor is one kind of chemical synthesis technology with chemical synthesis reaction inside miniature channel, and is one miniature continuous flow pipeline reactor with excellent mass and heat transfer effect, high reaction selectivity, high safety, high stability and other features. The reactor can contain a plurality of micro channels, fluid can flow in the reactor in a combined way in a specific physical state, meanwhile, the completion time of reaction and separation is shortened by strengthening the speed and controllability of the flow, mixing and transmission processes in the system, the retention of materials in the process is reduced, and the formation of byproducts is reduced, so that the environment-friendly, safe and efficient chemical process is realized. The microreactor is a novel technical equipment system developed in the fields of various process engineering such as chemical industry, energy sources, environment, materials and the like, and researches show that the mass transfer rate of the microreactor is higher by a plurality of orders of magnitude than that of the traditional microreactor, and the microreactor is suitable for reaction processes with higher requirements on the mass transfer rate, particularly reactions with strong exotherm and the like, so that the microreactor has important significance for researching the channel structure in the reactor and the reinforced mass transfer and heat transfer processes thereof At present, various microreactors are developed and applied to academic research or industrial application, such as Advanced-Flow microreactors of Corning, flowSyn systems of Uniqsis, flowPlate microreactors of Lonza and the like, which can perform chemical processes in a limited space with micrometer or millimeter scale, and through space design of a pipeline, the dispersion scale of the system is reduced to strengthen mixing and transmission, and the process controllability and efficiency are improved. However, the micro-reactor has small channel size, so that the phenomenon of channel blockage caused by catalyst accumulation is easy to form, the uniformity of the reaction process of the reactant precursor in the micro-channel is difficult to ensure, and the micro-reactor has potential for further development in structural design, processing and manufacturing and material development of the micro-reactor. Disclosure of Invention In order to solve the problems, one of the purposes of the invention is to provide a mesoscale flow reactor and a construction method thereof, wherein the catalytic efficiency of reactants is improved by improving the uniformity of the distribution of a catalyst on the wall of the reactor, the controllability of the reaction process and the mass and heat transfer efficiency are enhanced, the channel blockage caused by catalyst accumulation is avoided, and meanwhile, the construction method of the reactor is simple, and the batch amplification production can be carried out. As a first aspect of the present invention, there is provided a method of constructing a mesoscale flow reactor, comprising the steps of: s1, carrying out hydrophilic treatment on the surface of a hydrophobic flexible sub