CN-116875436-B - Full-automatic intelligent robot nucleic acid sampling, detecting and analyzing integrated workstation

CN116875436BCN 116875436 BCN116875436 BCN 116875436BCN-116875436-B

Abstract

The invention discloses a full-automatic intelligent robot nucleic acid sampling, detecting and analyzing integrated workstation which comprises a movable board room, wherein a plurality of unit compartments are sequentially arranged from left to right, each unit compartment is a sampling chamber, a sampling test tube feeding chamber, a sample preparation chamber and a detection and sample processing chamber from left to right, a transfer mechanism is arranged between every two adjacent unit compartments, the sampling test tube feeding chamber, the sample preparation chamber and the detection and sample processing chamber are all closed spaces, partition wall transmission holes are formed in the wall bodies of each unit compartment corresponding to the transfer mechanism, the transfer mechanism comprises a conveyor belt which is positioned at the bottoms of the partition wall transmission holes and extends leftwards and rightwards, and an airtight door which is arranged in the partition wall transmission holes and divides the conveyor belt into two sections of conveyor belts. The nucleic acid detection and analysis can be carried out by self-help collection of nucleic acid, the transfer to other places is not needed, the infection generated in the transfer process is avoided, and meanwhile, the nucleic acid sample collected from other places can be received for detection.

Inventors

GUO JINCHENG
DING YANRUI
WANG SHAN
JIN XIWEI

Assignees

重庆海润节能技术股份有限公司

Dates

Publication Date: 20260505
Application Date: 20230629

Claims (7)

1. The full-automatic intelligent robot nucleic acid sampling, detecting and analyzing integrated workstation is characterized by comprising a movable board room with a plurality of unit compartments sequentially arranged from left to right, wherein the unit compartments sequentially comprise a sampling chamber, a sampling test tube feeding chamber (S7), a sample preparation chamber (S4) and a detecting and sample processing chamber (S5) from left to right, a transmission mechanism is arranged between two adjacent unit compartments, the sampling test tube feeding chamber (S7), the sample preparation chamber (S4) and the detecting and sample processing chamber (S5) are all closed spaces, partition wall transmission holes (A10) are formed in the wall bodies of each unit compartment corresponding to the transmission mechanism, the transmission mechanism comprises a conveyor belt which is positioned at the bottom of the partition wall transmission hole (A10) and extends left and right, and an airtight door (A1) which is arranged in the partition wall transmission hole (A10) and divides the conveyor belt into two sections of the conveyor belt (A5); a first photoelectric sensor (A8) and a second photoelectric sensor (A11) which are fixed by a bracket (A9) are arranged beside the conveying belt, the first photoelectric sensor (A8) and the second photoelectric sensor (A11) are respectively arranged on two sides of a wall body, are respectively used for automatically identifying whether materials exist on a material starting position (A6) and a material ending position (A12) of the two-section conveying belt (A5) and are linked with a two-section conveying belt actuating mechanism (A7); The automatic sampling tube coding machine is characterized in that a sampling tube automatic coding machine (2) used for attaching information of personnel to be detected and a nucleic acid sampling robot (4) with a face recognition function are arranged in the sampling chamber, the nucleic acid sampling robot (4) is enclosed in a right corner of the sampling chamber through an isolation enclosing plate so as to be separated from other areas, the area is a sampling area (S6), the other areas are sampling tube preparation areas (S2), a house entrance door (J1) is arranged on a board room wall body of the sampling tube preparation areas (S2), a sampling tube rack feeding module (24) used for transmitting the sampling tubes is connected between the sampling tube preparation areas (S2) and the sampling area (S6), a sampling window is formed in the board room wall body of the sampling area (S6), an intelligent all-in-one machine (3) used for man-machine interaction is further arranged on the sampling window, the intelligent all-in-one machine (3) is electrically connected with an intelligent server (1), and a data transmission end of the automatic coding machine (2) is connected with a data transmission end of the intelligent all-in-one machine (3); a transmission mechanism for connecting the transmission mechanisms at the left side and the right side is arranged in the sampling test tube feeding chamber (S7), an outward-conveying sample transmission window (J5) in a normally closed state is arranged on a board room wall body of the sampling test tube feeding chamber (S7), and a nucleic acid sample collected elsewhere is placed on the transmission mechanism through the outward-conveying sample transmission window (J5); Ultraviolet sterilizing lamps (A4) are arranged on the upper side, the left side and the right side of two ends of an orifice of the partition wall transmission hole (A10), and an air curtain machine (A3) is arranged above the orifice end with high air pressure of the partition wall transmission hole (A10); The conveying belt is a two-section conveying belt (A5) which is respectively arranged at two sides of the wall body; the conveying belt comprises a two-section conveying belt actuating mechanism (A7) and a two-section conveying belt bracket (A13) which are arranged below the two-section conveying belt (A5); the airtight door (A1) is provided with a limit switch, so that the safety of a motor of the airtight door (A1) is protected; the two-stage conveyor belt (A5) includes a conveyor belt portion control circuit: The first end of the switch ZK is connected with the live wire L, the second end of the switch ZK is connected with the first end of the normally-open button switch SB1, the first end of the normally-open contact 1k of the photoelectric sensor I (A8) and the first end of the normally-open contact of the contactor KM1, the second end of the normally-open contact 1k of the photoelectric sensor I (A8) and the second end of the normally-open contact of the contactor KM1 and the first end of the normally-closed contact 1k1 of the photoelectric sensor II (A11); The second end of a normally closed contact 1k1 of a photoelectric sensor II (A11) is connected with the first end of a normally closed button switch SBS1, the second end of the normally closed button switch SBS1 is connected with the first end of a contactor KM1 winding and the first end of a contactor KM1 normally open contact, and the second end of the contactor KM1 normally open contact KM1 is connected with the first end of a contactor KM2 winding and the first end of a contactor KM3 winding; The airtight door (A1) includes an airtight door control circuit: The first end of the live wire main switch LK is connected with the live wire L, the second end of the live wire main switch LK is connected with the first end of the emergency stop switch SBS2, the second end of the emergency stop switch SBS2 is connected with the first end of the normally open contact of the contactor KM4, the first end of the normally open contact of the contactor KM3, the first end of the normally open contact SBS41 of the control button SBS4, the first end of the normally open contact SBS31 of the control button SBS3, the first end of the normally closed contact of the contactor KM3 and the first end of the normally open contact of the contactor KM5, and the second end of the normally open contact KM3 of the contactor KM3 is connected with the first end of the normally open contact of the contactor KM 5; The second end of the normally open contact of the contactor KM4, the second end of the normally open contact of the contactor KM5 and the second end of the normally open contact SBS41 of the control button SBS4 are connected with the first end of the control button SBS3, the second end of the control button SBS3 is connected with the first end of the normally closed limit switch SQ1, and the second end of the normally closed limit switch SQ1 is connected with the first end of the winding of the contactor KM 4; The second end of a normally-open contact SBS31 of the control button SBS31, the second end of a normally-closed contact of a contactor KM3 and the second end of a normally-open contact of a contactor KM5 are connected with the first end of a control button SBS4, the first end of a normally-closed limit switch contact SQ2 at the second end of the control button SBS4 is connected, the second end of the normally-closed limit switch contact SQ2 is connected with the first end of a normally-closed contact of a contactor KM4, and the second end of the normally-closed contact of the contactor KM4 is connected with the first end of a winding of the contactor KM 5; The second end of the contactor KM4 winding and the second end of the contactor KM5 winding are connected with the second end of a zero line main switch NK, and the first end of the zero line main switch NK is connected with a zero line N; The first end of the L pole of the normally open bipolar switch of the contactor KM4 is connected with the second end of the live wire main switch LK, the first end of the N pole of the normally open bipolar switch of the contactor KM4 is connected with the second end of the zero line main switch NK, the second end of the L pole of the normally open bipolar switch of the contactor KM4 is connected with the first end of the capacitor and the first end of the airtight door (A1) motor, the second end of the L pole of the normally closed bipolar switch of the contactor KM5 is connected with the second end of the N pole of the normally open bipolar switch of the contactor KM4 and the first end of the N pole of the normally closed bipolar switch of the contactor KM5, the second end of the L pole of the normally closed bipolar switch of the contactor KM5 is connected with the second end of the live wire main switch LK, and the second end of the N pole of the normally closed bipolar switch KM5 is connected with the second end of the zero line main switch.
2. The fully automatic intelligent robot nucleic acid sampling, detecting and analyzing integrated workstation according to claim 1, wherein a nucleic acid extractor upper/lower arm (10) and a nucleic acid extractor (9) and a pipetting/sealing film device (19) which are arranged around the nucleic acid extractor upper/lower arm (10) are arranged in the sample preparation chamber (S4), and samples extracted by the nucleic acid extractor (9), separated waste liquid and sampling tube waste materials are moved to a transfer mechanism between the sample preparation chamber (S4) and a detecting and sample processing chamber (S5) through the nucleic acid extractor upper/lower arm (10); The detection and specimen processing chamber (S5) is internally provided with a PCR (polymerase chain reaction) feeding/discharging arm (14) and a PCR detector (13), a specimen temporary storage rack (17) and an autoclave (16) which are arranged around the PCR feeding/discharging arm (14), a detection result data transmitting end of the PCR detector (13) is connected with a detection result data receiving end of the intelligent integrated machine (3), a right side plate house wall of the detection and specimen processing chamber (S5) is provided with an installing port for embedding and installing the autoclave (16), an exhaust port of the autoclave (16) is positioned outside the movable plate house, and a sterilization article transfer module (15) is connected between the specimen temporary storage rack (17) and the autoclave (16); A sampling pipe rack support (23) and a sampling pipe rack feeding arm (25) are arranged in the sampling pipe rack preparation area (S2), a sampling pipe rack (26) is placed on a sampling pipe rack feeding module (24) through the sampling pipe rack feeding arm (25), a transmission mechanism between the sampling area (S6) and a sampling test tube feeding chamber (S7) is a sampling pipe rack discharging module (5), and a sampling conveyor belt is connected between the sampling pipe rack discharging module (5) and the sampling pipe rack feeding module (24); The conveying mechanism between the sampling test tube feeding chamber (S7) and the sample preparation chamber (S4) is a sampling tube rack discharging module (8) to be detected, an external sampling tube rack (6) is arranged in the sampling test tube feeding chamber (S7) corresponding to an external sample conveying window (J5), and an external sampling tube rack conveying belt (7) is connected between the external sampling tube rack (6) and the sampling tube rack discharging module (8) to be detected.
3. The full-automatic intelligent robot nucleic acid sampling, detecting and analyzing integrated workstation according to claim 1, wherein the specimen preparation chamber (S4) is further communicated with a consumable and equipment preparation chamber (S3), a consumable support (21) and a consumable taking arm (22) are arranged in the consumable and equipment preparation chamber (S3), a consumable feeding module (20) is communicated between the consumable and equipment preparation chamber (S3) and the specimen preparation chamber (S4), and consumables on the consumable support (21) are placed on the consumable feeding module (20) through the consumable taking arm (22); The sample preparation room (S4) is interior corresponds consumptive material pay-off module (20) and wait to examine sample pipe support ejection of compact module (8) all to be provided with the pay-off conveyer belt, the transport mechanism between sample preparation room (S4) and detection and sample processing chamber (S5) includes PCR pay-off module (18), waste material transfer module (11) and sampling pipe waste material transmission module (12), the discharge end and the PCR pay-off module (18) intercommunication of pipetting/envelope equipment (19), in the end of PCR pay-off module (18) and the end of sampling pipe waste material transmission module (12) all stretched into detection and sample processing chamber (S5), sample and sampling pipe waste material that will seal up through PCR pay-off module (18) and sampling pipe waste material transmission module (12) are carried detection and sample processing chamber (S5) respectively and are handled.
4. The full-automatic intelligent robot nucleic acid sampling, detection and analysis integrated workstation according to claim 3, wherein the sampling test tube feeding chamber (S7) and the consumable and equipment preparation chamber (S3) are arranged in the same unit compartment and are arranged in the front-back close vicinity, and the sampling area (S6) is also arranged on the front side of the sampling chamber.
5. The full-automatic intelligent robot nucleic acid sampling, detection and analysis integrated workstation according to claim 1, wherein the sampling area (S6), the sampling test tube feeding chamber (S7), the sample preparation chamber (S4) and the board room wall of the detection and sample processing chamber (S5) are all provided with overhaul holes (J4).
6. The full-automatic intelligent robot nucleic acid sampling, detection and analysis integrated workstation according to claim 1, wherein a movable sunshade device (J2) is arranged outside the sampling window.
7. The full-automatic intelligent robot nucleic acid sampling, detection and analysis integrated workstation according to claim 1, wherein an equipment room (S1) is further arranged on the left side of the sampling room, the intelligent server is arranged in the equipment room (S1), monitoring equipment (27) is arranged in each unit room, monitoring data of all the monitoring equipment (27) are transmitted to the equipment room (S1), and a door (J1) is arranged in the equipment room (S1).

Description

Full-automatic intelligent robot nucleic acid sampling, detecting and analyzing integrated workstation Technical Field The invention relates to the technical field of medical detection equipment, in particular to a full-automatic intelligent robot nucleic acid sampling, detecting and analyzing integrated workstation. Background The development of nucleic acid detection has great practical significance and profound historical significance for early detection, clear target, definite direction, effective treatment, safety guarantee, reworking and production, economic recovery and promotion of economic and social development. However, in the existing sample collection and detection process, because of the problems of intensive personnel crossing, complicated procedure, untight protection, link separation, aging delay and the like, particularly the most common pharyngeal swab sampling and other methods, the problems of high risk of cross infection in the collection process, uneven collection method due to artificial factors, storage of collected sample delivery and the like exist, and the safety and efficiency of virus detection are greatly affected. Disclosure of Invention The invention aims to solve the technical problems in the prior art, and particularly creatively provides a full-automatic intelligent robot nucleic acid sampling, detecting and analyzing integrated workstation which can collect nucleic acid by self and directly carry out nucleic acid detection and analysis, does not need to be transported to other places, does not cause infection in the transportation process, and can also receive and detect nucleic acid samples collected from other places. In order to achieve the above purpose, the invention provides a full-automatic intelligent robot nucleic acid sampling, detecting and analyzing integrated workstation, which comprises a movable board house, wherein a plurality of unit compartments are sequentially arranged from left to right, the unit compartments are a sampling chamber, a sampling tube feeding chamber, a sample preparation chamber and a detecting and sample processing chamber from left to right, a transmission mechanism is arranged between two adjacent unit compartments, the sampling tube feeding chamber, the sample preparation chamber and the detecting and sample processing chamber are all closed spaces, partition wall transmission holes are arranged on the wall body of each unit compartment corresponding to the transmission mechanism, the transmission mechanism comprises a conveyor belt which is positioned at the bottom of the partition wall transmission hole and extends leftwards and rightwards, and an airtight door which is arranged in the partition wall transmission hole and divides the conveyor belt into two sections of conveyor belts; a first photoelectric sensor and a second photoelectric sensor which are fixed by a bracket are arranged beside the conveying belt, and the first photoelectric sensor and the second photoelectric sensor are respectively arranged on two sides of the wall body, are respectively used for automatically identifying whether materials exist on the material starting position and the material ending position of the two-section conveying belt and are linked with the two-section conveying belt driving mechanism; the automatic code printing machine is characterized in that a sampling pipe automatic code printing machine used for pasting information of personnel to be detected and a nucleic acid sampling robot with a face recognition function are arranged in the sampling chamber, the nucleic acid sampling robot is enclosed in a right corner of the sampling chamber through an isolation enclosing plate so as to be separated from other areas, the areas are sampling areas, the other areas are sampling pipe preparation areas, a house entrance door is arranged on a board room wall of the sampling pipe preparation area, a sampling pipe rack feeding module used for transmitting the sampling pipe is connected between the sampling pipe preparation area and the sampling area, a sampling window is formed in the board room wall of the sampling area, an intelligent all-in-one machine used for man-machine interaction is further arranged on the sampling window, the intelligent all-in-one machine is electrically connected with an intelligent server, and a data transmission end of the automatic code printing machine of the sampling pipe is connected with a data transmission end of the intelligent all-in-one machine; The sample tube feeding chamber is internally provided with a transmission mechanism for connecting transmission mechanisms at the left side and the right side, an outward sample transmission window in a normally closed state is arranged on a board room wall body of the sample tube feeding chamber, and a nucleic acid sample collected elsewhere is placed on the transmission mechanism through the outward sample transmission window. The sample preparation chamber is inter