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CN-116897919-B - Dual-purpose maintenance system for coring and extracorporeal maintenance of heart

CN116897919BCN 116897919 BCN116897919 BCN 116897919BCN-116897919-B

Abstract

The invention relates to a dual-purpose maintenance system for coring and in-vitro maintenance of a heart, which comprises a perfusion pipeline assembly and an organ box, wherein the operation of taking out and transferring the heart continuously can be supported through the design of communication and switching of the organ box and a blood storage container, and a pipeline is not required to be replaced in the conversion process, so that the thermal ischemia damage and ischemia reperfusion damage of the heart are reduced.

Inventors

  • WANG YUE
  • CAI JUN
  • PENG YATING
  • Ma Huaizheng

Assignees

  • 心擎医疗（苏州）股份有限公司

Dates

Publication Date
20260508
Application Date
20230711

Claims (10)

  1. 1. A dual use maintenance system for coring and extracorporeal maintenance of a heart, comprising: The heart infusion device comprises an infusion pipeline assembly (1) for infusing a heart, wherein the infusion pipeline assembly (1) comprises a first pipeline (11) and a second pipeline (12), one end of the first pipeline (11) is used for being connected with a vein of the heart, and one end of the second pipeline (12) is used for being connected with an aorta of the heart; An organ box (3) for accommodating a heart removed from a donor, wherein the organ box (3) is formed with a liquid collecting groove joint (33), the perfusion pipeline assembly (1) comprises a blood storage container (13) arranged on a first pipeline (11), and the liquid collecting groove joint (33) is connected with the blood storage container (13) through a recovery pipe (4); the first pipeline (11) and the recovery pipe (4) are respectively controllably communicated with or closed off from the blood storage container (13); the organ box (3) is provided with a first connection part (31) and a second connection part (32), the first connection part (31) can be detachably connected with the first pipeline (11) connected with the vein of the heart, and the second connection part (32) can be detachably connected with the second pipeline (12) connected with the aorta of the heart.
  2. 2. The dual use maintenance system according to claim 1, wherein the perfusion circuit assembly (1) comprises a fourth control valve (19) arranged between the organ box (3) and the blood storage container (13), the fourth control valve (19) being adapted to control the communication or closure of the first circuit (11) with the blood storage container (13).
  3. 3. The dual-purpose maintenance system according to claim 2, characterized in that the fourth control valve (19) is a three-way valve, the recovery tube (4) and the first conduit (11) being both in communication with the blood reservoir (13) through the fourth control valve (19).
  4. 4. The dual-purpose maintenance system according to claim 1, wherein the first pipeline (11) is provided with a first mounting portion (112), the second pipeline (12) is provided with a second mounting portion (121), the first mounting portion (112) is configured to be detachably connected to the first connecting portion (31), and the second mounting portion (121) is configured to be detachably connected to the second connecting portion (32).
  5. 5. The dual-purpose maintenance system according to claim 4, wherein one of the first mounting portion (112) and the first connecting portion (31) is configured as a snap-fit protrusion structure, and the other is configured as a snap-fit groove structure; One of the second mounting portion (121) and the second connecting portion (32) is configured as a snap-in protruding structure, and the other is configured as a snap-in groove structure.
  6. 6. The dual-purpose maintenance system according to any one of claims 1 to 5, characterized in that the periphery of said one end of said first conduit (11) is provided with a first balloon (111), said first balloon (111) being intended to be placed inside said vein, and said first balloon (111) having a first operating condition in which it does not close said vein and a second operating condition in which it completely closes said vein; the periphery of the one end of the second pipeline (12) is provided with a second air bag which is used for being placed in the aorta, and the second air bag has a third working state of not closing the aorta and a fourth working state of completely closing the aorta.
  7. 7. The dual use maintenance system according to any one of claims 1-5, characterized in that the outer circumference of the one end of the first and/or second tubing (11, 12) is provided with a plurality of clamping grooves for cooperating with wires to ligate the veins and/or aorta.
  8. 8. The dual-purpose maintenance system according to claim 1, wherein the perfusion tube assembly (1) comprises an oxygenation device (14), a centrifugal pump (15), a perfusion device (16) and a medicament supply device (17), wherein the oxygenation device (14) is used for oxygenating blood, the centrifugal pump (15) is used for driving blood flow in the perfusion tube assembly (1), the perfusion device (16) is used for inputting perfusion fluid into blood, and the medicament supply device (17) is used for inputting medicament into blood.
  9. 9. The dual-purpose maintenance system according to claim 1, further comprising a dialysis tubing assembly (2) connected at both ends to the perfusion tubing assembly (1) for selectively dialyzing blood in the perfusion tubing assembly (1); the dialysis tubing assembly (2) comprises: A dialysis circuit (21) having an inlet end and an outlet end connected to the perfusion circuit assembly (1), A dialysis device (22) provided on the dialysis line (21) for dialyzing blood; The perfusion circuit assembly (1) further comprises a first control valve (18), the first control valve (18) being located between the inlet end and the outlet end.
  10. 10. The dual purpose maintenance system of claim 9, wherein, The dialysis tubing assembly (2) further comprises a second drive pump (24), the second drive pump (24) being arranged on the dialysis tubing (21); The dialysis device (22) comprises a dialysis filter (221), a dialysis liquid container (222) and a third driving pump, wherein the dialysis filter (221) is arranged on the dialysis pipeline (21), the dialysis filter (221) is connected with the dialysis liquid container (222) through a circulation pipeline (225), and the third driving pump is used for driving dialysis liquid to circulate in the circulation pipeline (225).

Description

Dual-purpose maintenance system for coring and extracorporeal maintenance of heart Technical Field The invention relates to the technical field of medical equipment, in particular to a dual-purpose maintenance system for coring and in-vitro maintenance of a heart. Background With the development of medical technology, heart transplantation has become an effective method for treating end-stage heart disease, and the preservation effect on the donor heart directly affects the success rate of heart transplantation before heart transplantation operation. At present, in the process of heart transplantation, the heart is usually required to stop beating firstly, and then the heart is transferred to an organ transfer platform for perfusion and rebound, so that the heart is damaged by ischemia and reperfusion, and further the quality of organs, the number of available organs and the effect after transplantation are affected. Disclosure of Invention Based on the above-mentioned drawbacks of the prior art, an object of the present invention is to provide a dual-purpose maintenance system for coring and in vitro maintenance of a heart, which provides a perfusion function for the heart in two phases of coring and in vitro maintenance, and can support the continuous taking-out and transferring operations of the heart, reduce thermal ischemia damage and ischemia reperfusion damage of the heart, and improve the utilization rate of the heart donor. Therefore, the invention provides the following technical scheme. A dual-purpose maintenance system for coring and in-vitro maintenance of a heart comprises a perfusion pipeline assembly, a first pipeline and a second pipeline, wherein the perfusion pipeline assembly is used for perfusing the heart; The perfusion pipeline assembly comprises a first pipeline, an organ box, a perfusion pipeline assembly and a second pipeline, wherein the first pipeline is used for connecting a donor, the organ box is used for accommodating a heart taken down from the donor, and is provided with a liquid collecting groove joint, and the perfusion pipeline assembly comprises a blood storage container arranged on the first pipeline; The first pipeline and the recovery pipe are respectively and controllably communicated with or closed off from the blood storage container. Preferably, the perfusion circuit assembly includes a fourth control valve disposed between the organ box and the blood storage container for controlling communication or closure of the first circuit with the blood storage container. Preferably, the fourth control valve is a three-way valve, and the recovery pipe and the first pipeline are communicated with the blood storage container through the fourth control valve. Preferably, the organ box is provided with a first connection part detachably connectable with the first line of the vein connected to the heart, and a second connection part detachably connectable with the second line of the aorta connected to the heart. Preferably, the first pipeline is provided with a first installation part, the second pipeline is provided with a second installation part, the first installation part is used for being detachably connected with the first connection part, and the second installation part is used for being detachably connected with the second connection part. Preferably, one of the first mounting portion and the first connecting portion is configured as a snap-fit protrusion structure, and the other is configured as a snap-groove structure; one of the second mounting part and the second connecting part is constructed as a clamping convex structure, and the other is constructed as a clamping groove structure. Preferably, the periphery of one end of the first pipeline is provided with a first air bag which is used for being placed in the vein, and the first air bag has a first working state of not closing the vein and a second working state of completely closing the vein; the periphery of one end of the second pipeline is provided with a second air bag, the second air bag is used for being placed in the aorta, and the second air bag has a third working state of not closing the aorta and a fourth working state of completely closing the aorta. Preferably, the periphery of the one end of the first and/or second tube is provided with a plurality of clamping grooves for cooperating with wires to ligate the vein and/or aorta. Preferably, the perfusion pipeline assembly comprises an oxygenation device, a centrifugal pump, a perfusion device and a medicament supply device, wherein the oxygenation device is used for oxygenation of blood, the centrifugal pump is used for driving blood in the perfusion pipeline assembly to flow, the perfusion device is used for inputting perfusion liquid into the blood, and the medicament supply device is used for inputting medicament into the blood. Preferably, the device further comprises a dialysis pipeline assembly, wherein two ends of the dialysis pipeline asse