CN-116898468-B - Dynamic quality control method of D-SPECT system

CN116898468BCN 116898468 BCN116898468 BCN 116898468BCN-116898468-B

Abstract

The invention provides a dynamic quality control method of a D-SPECT system, which comprises the following steps of obtaining a plurality of scanning data of a radioactive source simulation nuclide in a first duration by a plurality of detection units, dividing the plurality of scanning data into a plurality of first sub-data sets corresponding to different time points according to time information, dividing each scanning data into a second sub-data set corresponding to different positions according to space information, obtaining uniformity and/or resolution of the scanning data according to the plurality of first sub-data sets, obtaining a plurality of time activity curves according to the plurality of second sub-data sets, and determining dynamic scanning quality of the D-SPECT system according to the uniformity of the scanning data, the resolution of the scanning data and/or the plurality of time activity curves. According to the quality control method, the dynamic scanning quality of the system is evaluated through the scanning data of the D-SPECT system on the radioactive source simulated nuclide, and whether the D-SPECT system needs further adjustment or meets the requirement on target data can be determined according to the dynamic scanning quality evaluation result.

Inventors

You Er
MA ZHIFU
YANG ZHISHAN
Zhang Zhuodong

Assignees

上海光脉医疗科技有限公司

Dates

Publication Date: 20260512
Application Date: 20230714

Claims (6)

1. A dynamic quality control method of a D-SPECT system, wherein the D-SPECT system includes an L-type tomographic probe provided with a plurality of detection units, a radioactive source simulation nuclide, an adjustable clamp, and a processing unit; one end of the adjustable clamp is connected with the L-shaped tomography probe; the other end of the adjustable clamp is connected with the radioactive source simulation nuclide; the processing unit is connected with the L-shaped tomography probe and receives photon scanning data of the L-shaped tomography probe on the radioactive source simulation nuclide; the distance between the radioactive source simulated nuclide and the central position of the folded angle of the L-shaped tomography probe can be adjusted by the adjustable clamp; The quality control method comprises the following steps: adjusting the distance between the radioactive source simulation nuclide and the central position of the folded angle of the L-shaped tomography probe according to application parameters, wherein the application parameters are determined according to a target scanning object; The detection units acquire a plurality of scanning data of the radioactive source simulation nuclide in a first duration, wherein each scanning data respectively comprises time information and space information; dividing the scanning data into a plurality of first sub-data sets corresponding to different time points according to time information, and dividing each scanning data into a second sub-data set corresponding to different positions according to space information; obtaining uniformity and resolution of the scan data from a plurality of the first sub-data sets and obtaining a plurality of time activity curves from a plurality of the second sub-data sets; The dynamic scan quality of the D-SPECT system is determined from the uniformity of the scan data, the resolution of the scan data, and a plurality of the time activity curves.
2. The method of claim 1, wherein the distance between the radionuclide and the central position at the break angle of the L-shaped tomographic imaging probe is in the range of 10cm to 20cm.
3. The method of claim 1, further comprising, after the step of obtaining a plurality of time activity curves from a plurality of the second sub-data sets: and obtaining the attenuation rate according to the time activity curve.
4. The method of dynamic quality control of a D-SPECT system of claim 1 wherein the obtaining uniformity and resolution of the scan data from a plurality of the first sub-data sets includes the steps of: Obtaining a panoramic view of the corresponding time point of the radionuclide for the radiation source simulation according to the first sub-data set of each time point; and obtaining the uniformity and resolution of the scanning data of the corresponding time points according to the panoramic image of each time point.
5. A method of dynamic quality control of a D-SPECT system according to claim 3 wherein the determining the dynamic scan quality of the D-SPECT system from the uniformity of the scan data, the resolution of the scan data, and a plurality of the time activity curves includes the steps of: Judging whether the uniformity is larger than a first threshold value; judging whether the resolution is larger than a second threshold value; Judging whether the absolute value of the difference value between the attenuation rate and the attenuation rate of the radioactive source simulation nuclide is larger than a third threshold value; If the above condition or conditions are met, then the dynamic scan quality of the D-SPECT system is deemed to not meet the set requirements.
6. The method of dynamic quality control of a D-SPECT system of claim 1 wherein the radioactive source of the radioactive source-mimicking nuclear species is Co-57 and the first duration is 390 seconds.

Description

Dynamic quality control method of D-SPECT system Technical Field The invention relates to the technical field of medical imaging, in particular to a dynamic quality control method of a D-SPECT system. Background The conventional quality control project of the conventional SPECT mainly comprises inherent spatial resolution, uniformity, planar sensitivity, inherent spatial linearity, center of rotation drift and the like, wherein the inherent spatial resolution, the inherent spatial linearity, the center of rotation drift are generally stable, but uniformity, energy peaks and resolution are easy to change, the conventional SPECT is subjected to quality control by using 99 technetium marking liquid medicine sources with different shapes and different distances from a detector, collimators with different shapes are also required to be replaced, the quality control time is long, the process is complicated, the radiation dose of a quality control operator is relatively high, special quality control cannot be performed for the dynamic acquisition of the heart, the conventional quality control cannot be performed only before the dynamic acquisition of the heart, the performance state before the dynamic acquisition of the heart can not be well confirmed, and the factors seriously affect the quality control scanning of the performance state before the dynamic acquisition of the heart of the SPECT, so that the whole process of the dynamic acquisition of the heart is seriously affected, and the interpretation of clinical image results is seriously affected. The heart is vital to the human body, and is one of the most important organs of the human body, and the heart pumps blood through blood vessels to provide necessary energy for all activities of the human body, and in the process, the heart itself is also required to supply blood, for example, if the heart muscle itself and/or coronary arteries supplying the heart muscle are diseased, the blood supply function of the heart is seriously affected, and even the human life is endangered. Among them, the heart disease caused by coronary artery stenosis and the heart disease caused by heart microvascular lesion are the most fatal, and the two diseases can cause serious defect of myocardial blood supply, thus serious heart adverse events occur, and life is endangered. Therefore, monitoring the effect of preventing and accurately diagnosing coronary stenosis on cardiac blood supply and whether there are microvascular lesions and the extent of the effect of lesions on myocardial blood supply is of paramount importance. Currently, the most advanced monitoring, prevention and diagnosis means mainly include positron emission computed tomography (positron emission tomography, PET) and SPECT to measure myocardial blood flow reserve (Myocardial Flow Reserve, MFR), also called coronary blood flow reserve (Coronary Flow Reserve, CFR), wherein radionuclides (such as 18F labeled oxygen water) required for PET are produced by using cyclotrons, which have high cost, short half-life, difficult transportation and storage, and too high cost of PET itself. In contrast, SPECT uses 99 technetium labeled drugs with a longer half-life, both at cost and for transport and storage, far superior to the nuclides required for PET, and SPECT measured CFR values have a high correlation and consistency with PET as reported in the relevant literature. Therefore, the use of SPECT for CFR measurement is one of the most recommended noninvasive examination and diagnosis means in the fields of cardiovascular and nuclear medicine at home and abroad at present. In order to ensure the stability of the performance and the accuracy of the image result during the dynamic acquisition of the SPECT on the heart, shorten the time for acquiring the dynamic quality control of the heart and improve the efficiency of the dynamic quality control of the heart, a concise, rapid and higher-result-accuracy SPECT dynamic quality control method is needed. It should be noted that the information disclosed in the foregoing background section is only for enhancement of understanding of the background of the invention and thus may include information that does not form the prior art that is already known to those of skill in the art. Disclosure of Invention Aiming at the problems in the prior art, the invention aims to provide a dynamic quality control method of a D-SPECT system, wherein the dynamic scanning quality of the system is evaluated through the scanning data of the D-SPECT system on the radionuclide-simulated radionuclides, and whether the D-SPECT system needs further adjustment or meets the requirement on target data can be determined according to the dynamic scanning quality evaluation result. The embodiment of the invention provides a dynamic quality control method of a D-SPECT system, which comprises an L-shaped tomographic imaging probe provided with a plurality of detection units, a radioactive source simulated nuclid