CN-117379022-B - Method, device and equipment for acquiring hemodynamic parameters of lower limbs

CN117379022BCN 117379022 BCN117379022 BCN 117379022BCN-117379022-B

Abstract

The application provides a method, a device and equipment for acquiring hemodynamic parameters of lower limbs, which relate to the technical field of noninvasive detection and comprise the steps of acquiring a first foot pulse wave sequence in a first pressurizing mode, a second foot pulse wave sequence in a second pressurizing mode, a third foot pulse wave sequence in a third pressurizing mode and a corresponding air pressure sequence aiming at blood vessels of lower limbs of a user, carrying out trend analysis on the first foot pulse wave sequence to obtain first hemodynamic parameters of the lower limbs, carrying out analysis on the second foot pulse wave sequence to obtain second hemodynamic parameters, carrying out analysis on the third foot pulse wave sequence to obtain correction parameters, correcting the second hemodynamic parameters by utilizing the correction parameters, and obtaining the hemodynamic parameters of the lower limbs based on the first hemodynamic parameters and the corrected second hemodynamic parameters. The application realizes the non-invasive measurement of the hemodynamic parameters of the lower limbs and the distinction of the arteriovenous hemodynamic parameters.

Inventors

WANG YAWEI
LIU HANHAO
FAN YUBO
WANG BITIAN

Assignees

北京航空航天大学

Dates

Publication Date: 20260505
Application Date: 20231013

Claims (10)

1. A method for obtaining hemodynamic parameters of a lower limb, the method comprising: Aiming at lower limb blood vessels of a user, acquiring a first foot pulse wave sequence in a first pressurizing mode, a second foot pulse wave sequence in a second pressurizing mode, a third foot pulse wave sequence in a third pressurizing mode and an air pressure sequence corresponding to the foot pulse wave sequence, wherein the foot pulse wave sequence is formed by arranging acquired foot pulse waves according to an acquisition time sequence; performing trend analysis on the first foot pulse wave sequence to obtain a trend change analysis result of the first foot pulse wave sequence; extracting the air pressure corresponding to the first time parameter from the air pressure sequence to obtain first air pressure; based on the trend change analysis result of the first foot pulse wave sequence and the first air pressure, obtaining a first hemodynamic parameter of a lower limb; The second foot pulse wave sequence is subjected to peak-to-peak value extraction, polynomial fitting analysis is carried out on the extracted peak-to-peak value, and a polynomial fitting analysis result is obtained; Obtaining a second hemodynamic parameter of the lower limb based on a second foot pulse wave with the maximum pulse wave value and the polynomial fitting analysis result, wherein the second hemodynamic parameter comprises a second venous hemodynamic parameter and a second arterial hemodynamic parameter; analyzing the third foot pulse wave sequence to obtain a first correction parameter and a second correction parameter; correcting the second arterial hemodynamic parameter by using the first correction parameter and the second correction parameter to obtain a corrected second arterial hemodynamic parameter; And combining the first hemodynamic parameter of the lower limb, the second venous hemodynamic parameter and the corrected second arterial hemodynamic parameter to obtain the hemodynamic parameter of the lower limb.
2. The method of claim 1, wherein the first pressurization mode comprises at least a first high pressure duration phase; performing trend analysis on the first foot pulse wave sequence to obtain a trend change analysis result of the first foot pulse wave sequence, wherein the trend change analysis result comprises the following steps: aiming at a first foot pulse wave sequence of any first high-pressure continuous stage, carrying out low-pass filtering on the first foot pulse wave sequence of the first high-pressure continuous stage to obtain a filtered first foot pulse wave sequence; Analyzing the change trend of the filtered first foot pulse wave sequence to obtain an initial trend change analysis result of the first foot pulse wave sequence in a first high-pressure continuous stage; And screening the obtained initial trend change analysis results of the first foot pulse wave sequences in a plurality of first high-pressure continuous stages to obtain trend change results of the first foot pulse wave sequences.
3. The method of claim 1, wherein the foot pulse wave train is comprised of a plurality of foot pulse wave train subsections, each foot pulse wave train subsection corresponding to a cardiac cycle, each foot pulse wave train subsection comprising a foot pulse wave train ascending subsection and a foot pulse wave train descending subsection; Before acquiring the first foot pulse wave sequence in the first pressurization mode, the method further includes: acquiring a resting foot pulse wave sequence, wherein the resting foot pulse wave sequence is formed by arranging foot pulse waves acquired when pressure is not applied to lower limbs of a user according to an acquisition time sequence; Dividing the resting foot pulse wave sequence according to a cardiac cycle to obtain a plurality of resting foot pulse wave sequence subsections; Extracting the maximum value point and the minimum value point of the ascending sub-section of the resting foot pulse wave sequence aiming at any resting foot pulse wave sequence sub-section, and subtracting the minimum value point from the maximum value point of the ascending sub-section to obtain the peak-to-peak value of the ascending sub-section; extracting the maximum value point and the minimum value point of the descending subsections of the resting foot pulse wave sequence, and subtracting the minimum value point from the maximum value point of the descending subsections to obtain the peak-to-peak value of the descending subsections; removing abnormal resting foot pulse wave sequence subsections according to the peak-to-peak value of the ascending subsections and the peak-to-peak value of the descending subsections to obtain a plurality of non-abnormal resting foot pulse wave sequence subsections, wherein the abnormal resting foot pulse wave sequence subsections are resting foot pulse wave sequence subsections of which the peak-to-peak value of the ascending subsections divided by the peak-to-peak value of the descending subsections does not meet a first threshold value; Calculating the average value of the peak-to-peak value of the ascending sub-section and the peak-to-peak value of the descending sub-section aiming at any non-abnormal resting foot pulse wave sequence sub-section to obtain the peak-to-peak value of the non-abnormal resting foot pulse wave sequence sub-section; Calculating peak-to-peak values of all non-abnormal resting foot pulse wave sequence subsections according to the peak-to-peak values of the non-abnormal resting foot pulse wave sequence subsections, and obtaining average amplitude of a user; And determining the total duration and total number of the non-abnormal resting foot pulse wave sequence subsections, and obtaining the heart rate of the user based on the total duration and the total number.
4. The method of claim 3, wherein the second pressurization mode comprises a second depressurization stage; Performing polynomial fitting analysis on the extracted peak value and the extracted peak value to obtain a polynomial fitting analysis result, wherein the method comprises the following steps of: extracting a second foot pulse wave sequence of the second depressurization stage to obtain a second foot pulse wave sequence to be analyzed; deriving the second foot pulse wave sequence to be analyzed to obtain an extreme point of the second foot pulse wave sequence to be analyzed; Removing dicrotic notch in the second foot pulse wave sequence to be analyzed according to the heart rate of the user, the average amplitude of the user and the extreme point of the second foot pulse wave sequence to be analyzed to obtain a second foot pulse wave sequence to be fitted; dividing the second foot pulse wave sequence to be fitted according to a cardiac cycle to obtain a plurality of second foot pulse wave sequence subsections; fitting the peak-to-peak values of all the sub-sections of the second foot pulse wave sequence to obtain a peak-to-peak value fitting curve of the second foot pulse wave sequence; and extracting zero points, maximum points and stable points of a peak-to-peak fitting curve of the second foot pulse wave sequence as polynomial fitting results.
5. The method of claim 4, wherein deriving a second hemodynamic parameter of the lower limb based on the second foot pulse wave having the greatest pulse wave value and the polynomial fit analysis result comprises: Extracting the time corresponding to the zero point of the peak-to-peak fitting curve of the second foot pulse wave sequence in the polynomial fitting analysis result to obtain a second time parameter; Extracting the time corresponding to the maximum value point of the peak-to-peak fitting curve of the second foot pulse wave sequence in the polynomial fitting analysis result to obtain a third time parameter; Extracting the time corresponding to the stable point of the peak-to-peak fitting curve of the second foot pulse wave sequence in the polynomial fitting analysis result to obtain a fourth time parameter; extracting the time corresponding to the second foot pulse wave with the maximum pulse wave value to obtain a fifth time parameter; extracting the air pressure corresponding to the second time parameter and the air pressure corresponding to the third time parameter from the air pressure sequence to obtain a second arterial hemodynamic parameter; extracting air pressure corresponding to the fourth time parameter and air pressure corresponding to the fifth time parameter from the air pressure sequence to obtain a second venous hemodynamic parameter; And obtaining the second hemodynamic parameters of the lower limbs of the user based on the second arterial hemodynamic parameters and the second venous hemodynamic parameters.
6. A method according to claim 3, wherein the third pressurization mode comprises at least two third high pressure duration phases; Analyzing the third foot pulse wave sequence to obtain a first correction parameter and a second correction parameter, wherein the first correction parameter and the second correction parameter comprise: extracting third foot pulse wave sequences of all third high-pressure continuous phases; Aiming at a third foot pulse wave sequence of any third high-pressure continuous stage, deriving the third foot pulse wave sequence of the third high-pressure continuous stage to obtain an extreme point of the third foot pulse wave sequence to be analyzed; removing dicrotic notch in the third foot pulse wave sequence to be analyzed according to the heart rate of the user, the average amplitude of the user and the extreme point of the third foot pulse wave sequence to be analyzed; dividing the third foot pulse wave sequence to be analyzed after the dicrotic notch is removed according to the cardiac cycle to obtain a plurality of third foot pulse wave sequence subsections; calculating the average value of the peak values of all the third foot pulse wave sequence subsections according to the peak value of each third foot pulse wave sequence subsection; arranging the average value of the peak values of all the third foot pulse wave sequence subsections according to a time sequence; Selecting the time corresponding to the maximum value from the average value of the peak values of all the arranged third foot pulse wave sequence subsections to obtain a sixth time parameter; selecting a time corresponding to a value which is 0 at first from the average value of the peak values of the arranged third foot pulse wave sequence subsections, and obtaining a seventh time parameter; Extracting air pressure corresponding to the sixth time parameter from the air pressure sequence to obtain a first correction parameter; And extracting the air pressure corresponding to the seventh time parameter from the air pressure sequence to obtain a second correction parameter.
7. The method of claim 5, wherein the second arterial hemodynamic parameter comprises a second arterial pressure parameter and a second arterial feature parameter, wherein the second arterial pressure parameter is a pressure corresponding to a second time parameter; correcting the second arterial hemodynamic parameter by using the first correction parameter and the second correction parameter to obtain a corrected second arterial hemodynamic parameter, including: correcting the second arterial pressure parameter by using the first correction parameter to obtain a corrected second arterial pressure parameter; correcting the second arterial characteristic parameter by using a second correction parameter to obtain a corrected second arterial characteristic parameter; And obtaining the corrected second arterial hemodynamic parameter based on the corrected second arterial pressure parameter and the corrected second arterial characteristic parameter.
8. An apparatus for obtaining hemodynamic parameters of a lower limb, the apparatus comprising: The system comprises a signal acquisition unit, a first pressure mode, a second pressure mode, a third pressure mode, a first foot pulse wave sequence, a second foot pulse wave sequence and a third foot pulse wave sequence, wherein the signal acquisition unit is used for acquiring a first foot pulse wave sequence in the first pressure mode, a second foot pulse wave sequence in the second pressure mode and a third foot pulse wave sequence in the third pressure mode and an air pressure sequence corresponding to the foot pulse wave sequence aiming at a lower limb blood vessel of a user; the trend analysis unit is used for carrying out trend analysis on the first foot pulse wave sequence to obtain a trend change analysis result of the first foot pulse wave sequence, extracting time corresponding to the trend change analysis result to obtain a first time parameter, extracting air pressure corresponding to the first time parameter from the air pressure sequence to obtain a first air pressure, and obtaining a first hemodynamic parameter of a lower limb based on the trend change analysis result of the first foot pulse wave sequence and the first air pressure; the fitting analysis unit is used for extracting peaks and peaks of the second foot pulse wave sequence, carrying out polynomial fitting analysis on the extracted peaks and peaks to obtain a polynomial fitting analysis result, extracting a second foot pulse wave with the maximum pulse wave value from the second foot pulse wave sequence, and obtaining a second hemodynamic parameter of a lower limb based on the second foot pulse wave with the maximum pulse wave value and the polynomial fitting analysis result, wherein the second hemodynamic parameter comprises a second venous hemodynamic parameter and a second arterial hemodynamic parameter; The correction unit is used for analyzing the third foot pulse wave sequence to obtain a first correction parameter and a second correction parameter, and correcting the second arterial hemodynamic parameter by utilizing the first correction parameter and the second correction parameter to obtain a corrected second arterial hemodynamic parameter; And the output unit is used for combining the first hemodynamic parameter of the lower limb, the second venous hemodynamic parameter and the corrected second arterial hemodynamic parameter to obtain the hemodynamic parameter of the lower limb.
9. An electronic device, characterized in that the electronic device comprises a processor, a communication interface, a memory and a communication bus, wherein the processor, the communication interface and the memory are in communication with each other through the communication bus; a memory for storing a computer program; a processor for implementing the method of any of claims 1-7 when executing a program stored on a memory.
10. A computer readable storage medium, characterized in that the computer readable storage medium has stored therein a computer program which, when executed by a processor, implements the method of any of claims 1-7.

Description

Method, device and equipment for acquiring hemodynamic parameters of lower limbs Technical Field The application relates to the technical field of noninvasive detection, in particular to a method, a device and equipment for acquiring hemodynamic parameters of lower limbs. Background The existing detection of the structure, function and corresponding parameters of the blood vessel mainly aims at the arterial blood vessel, particularly the arterial blood vessel of the upper limb, the detection result can only reflect the condition of the arterial blood vessel of the upper limb, and no technology for detecting the structure, function and corresponding hemodynamic parameters of the blood vessel of the lower limb exists at present. The existing blood vessel detection method is divided into invasive detection and noninvasive detection, wherein the invasive detection has high accuracy, invasive detection needs invasive operation, a certain degree of damage is brought to a body, wounds are left, complications such as infection, thrombus and hemorrhage can be caused due to improper operation, the complication occurrence rate of noninvasive detection is low, the use is convenient, but the noninvasive detection at the present stage lacks complete theoretical guidance, and the defects of low accuracy, incapacity of effectively distinguishing blood vessel signal characteristics of transfer veins and the like are overcome. Disclosure of Invention The embodiment of the application aims to provide a method, a device and equipment for acquiring hemodynamic parameters of lower limbs, which are used for solving the problems that the hemodynamic parameters of the lower limbs and the hemodynamic parameters of transfer veins cannot be detected and can be distinguished in the prior art, realizing noninvasive measurement of the hemodynamic parameters of the lower limbs by using a PPG sensor and realizing distinction of the hemodynamic parameters of the arteries and veins. In a first aspect, a method for obtaining a hemodynamic parameter of a lower limb is provided, the method may include: Aiming at lower limb blood vessels of a user, acquiring a first foot pulse wave sequence in a first pressurizing mode, a second foot pulse wave sequence in a second pressurizing mode, a third foot pulse wave sequence in a third pressurizing mode and an air pressure sequence corresponding to the foot pulse wave sequence, wherein the foot pulse wave sequence is formed by arranging acquired foot pulse waves according to an acquisition time sequence; performing trend analysis on the first foot pulse wave sequence to obtain a trend change analysis result of the first foot pulse wave sequence; extracting the air pressure corresponding to the first time parameter from the air pressure sequence to obtain first air pressure; based on the trend change analysis result of the first foot pulse wave sequence and the first air pressure, obtaining a first hemodynamic parameter of a lower limb; The second foot pulse wave sequence is subjected to peak-to-peak value extraction, polynomial fitting analysis is carried out on the extracted peak-to-peak value, and a polynomial fitting analysis result is obtained; Obtaining a second hemodynamic parameter of the lower limb based on a second foot pulse wave with the maximum pulse wave value and the polynomial fitting analysis result, wherein the second hemodynamic parameter comprises a second venous hemodynamic parameter and a second arterial hemodynamic parameter; analyzing the third foot pulse wave sequence to obtain a first correction parameter and a second correction parameter; correcting the second arterial hemodynamic parameter by using the first correction parameter and the second correction parameter to obtain a corrected second arterial hemodynamic parameter; And combining the first hemodynamic parameter of the lower limb, the second venous hemodynamic parameter and the corrected second arterial hemodynamic parameter to obtain the hemodynamic parameter of the lower limb. In an alternative implementation, the first pressurization mode includes at least a first high pressure duration phase; performing trend analysis on the first foot pulse wave sequence to obtain a trend change analysis result of the first foot pulse wave sequence, wherein the trend change analysis result comprises the following steps: aiming at a first foot pulse wave sequence of any first high-pressure continuous stage, carrying out low-pass filtering on the first foot pulse wave sequence of the first high-pressure continuous stage to obtain a filtered first foot pulse wave sequence; Analyzing the change trend of the filtered first foot pulse wave sequence to obtain an initial trend change analysis result of the first foot pulse wave sequence in a first high-pressure continuous stage; And screening the obtained initial trend change analysis results of the first foot pulse wave sequences in a plurality of first high-pressure continuous stages to o