Search

CN-118141940-B - Hot melt adhesive for infant navel patch, preparation method thereof and infant navel patch containing same

CN118141940BCN 118141940 BCN118141940 BCN 118141940BCN-118141940-B

Abstract

The application provides a hot melt adhesive for an infant navel patch, a preparation method thereof and an infant navel patch containing the same, and relates to the technical field of medical appliances. The hot melt adhesive for the infant navel patch mainly comprises a thermoplastic copolymer, mineral oil, tackifying resin, cellulose, anti-inflammatory substances and antioxidants, wherein the mass ratio of the thermoplastic copolymer to the tackifying resin to the cellulose is 10-20:20-30:20-50. The long-term experimental study of the applicant shows that the hot melt adhesive obtained by the mass ratio of the thermoplastic copolymer to the tackifying resin to the cellulose has good adhesive viscosity and proper peeling force at the temperature of 35-40 ℃, and the hot melt adhesive can realize the technical effects of good adhesive property, no pain and easy tearing when being used as the navel patch for infants. Meanwhile, the hot melt adhesive also contains anti-inflammatory substances, and all the used raw materials have no allergic irritation, so that the hot melt adhesive for the infant navel patch also has good anti-inflammatory and anti-allergic effects.

Inventors

  • GE JINGJING
  • SONG YUBIN
  • JIAN WENXIANG

Assignees

  • 华威粘结材料（上海）股份有限公司

Dates

Publication Date
20260512
Application Date
20240308

Claims (6)

  1. 1. The hot melt adhesive for infant navel patch is characterized in that the hot melt adhesive is mainly prepared from thermoplastic copolymer, mineral oil, tackifying resin, cellulose, anti-inflammatory substances and antioxidants, wherein: the mass ratio of the thermoplastic copolymer to the tackifying resin to the cellulose is 10-20:20-30:20-50; The hot melt adhesive comprises the following components in parts by mass: 10-20 parts of thermoplastic copolymer, 5-10 parts of mineral oil, 20-30 parts of tackifying resin, 20-50 parts of cellulose, 1-10 parts of anti-inflammatory substances and 0.1-0.5 part of antioxidant; The thermoplastic copolymer is obtained by compounding a styrene-isoprene block copolymer and a hydrogenated styrene-butadiene block copolymer; the tackifying resin is C5 or C9 petroleum resin; the cellulose is at least one of methyl cellulose, hydroxypropyl methyl cellulose, hydroxyethyl cellulose and carboxymethyl cellulose; the anti-inflammatory substance is zirconium phosphate silver-loaded inorganic antibacterial powder.
  2. 2. The hot melt adhesive for infant navel patch according to claim 1, wherein a weight ratio of the styrene-isoprene block copolymer to the hydrogenated styrene-butadiene block copolymer is 10 to 15:5.
  3. 3. The hot melt adhesive for infant navel patch according to claim 1, wherein the mineral oil is naphthenic oil or white mineral oil; The antioxidant is a hindered phenol antioxidant, and the hindered phenol antioxidant is a Pasteur antioxidant irganox B and 2, 6-di-tert-butyl 4 One or two of methylphenols.
  4. 4. A method for preparing the hot melt adhesive for infant umbilicus patch according to any one of claims 1 to 3, characterized in that the method comprises: (A) Heating, melting and mixing part of tackifying resin with mineral oil and antioxidant uniformly to obtain an intermediate A; (B) Adding a thermoplastic copolymer into the intermediate A, heating and stirring until the thermoplastic copolymer is melted, then adding the rest tackifying resin, heating and stirring until the tackifying resin is melted, and then adding cellulose and an anti-inflammatory substance, heating and stirring until the thermoplastic copolymer is melted to obtain an intermediate B; (C) Cooling the intermediate B to obtain the hot melt adhesive for the navel patch of the infant; The heating and melting temperature in the step (A) is 140-145 ℃; And (C) heating and stirring in the step (B) until the melting temperature is 140-145 ℃.
  5. 5. The method for preparing a hot melt adhesive for infant navel patch according to claim 4, wherein the tackifying resin in the step (a) is 40% of the total mass of the tackifying resin; The tackifying resin added in the step (B) accounts for 60% of the total mass of the tackifying resin; And (3) preparing in the step (B) under the condition of negative pressure air suction.
  6. 6. An infant umbilical patch, characterized in that the infant umbilical patch comprises a backing layer and a sol layer; the sol layer is mainly prepared from the hot melt adhesive for infant navel plaster according to any one of claims 1 to 3.

Description

Hot melt adhesive for infant navel patch, preparation method thereof and infant navel patch containing same Technical Field The invention relates to the technical field of medical equipment, in particular to a hot melt adhesive for an infant navel patch, a preparation method thereof and the infant navel patch containing the same. Background The navel patch for infants is often used for preventing infection after the neonate shears the umbilical cord at birth. In long-term clinical practice, after a doctor sticks a navel patch to a child, the navel patch is stuck to the abdomen of the child by using a medical adhesive tape, and often the navel patch is easy to rub due to frequent movement of the child, and the existing navel patch usually contains adhesive components such as rubber, so that the skin of the infant is tender, allergic reaction can be generated on the substances, and the phenomena such as red swelling, inflammation and the like of navel eyes are caused. Meanwhile, in the existing navel patch product, the anti-inflammatory medicine in the navel patch can be gradually volatilized and lose efficacy after being placed for a long time. Therefore, the infant navel patch which has good application property, no pain and easy tearing and has good anti-inflammatory and antiallergic effects under the condition of body temperature (35-40 ℃) is researched and developed, and becomes necessary and urgent. In view of this, the present invention has been made. Disclosure of Invention The first aim of the invention is to provide the hot melt adhesive for the infant navel patch, which has good adhesive viscosity and proper peeling force at the temperature of 35-40 ℃, and can realize the technical effects of good adhesive property, no pain and easy tearing when being used as the hot melt adhesive for the infant navel patch. The second aim of the invention is to provide a preparation method of the hot melt adhesive for the navel patch of infants. The third object of the present invention is to provide an infant umbilical paste, wherein the sol layer of the infant umbilical paste is mainly prepared from the hot melt adhesive for infant umbilical paste. In order to achieve the above object of the present invention, the following technical solutions are specifically adopted: the invention provides a hot melt adhesive for infant navel plaster, which is mainly prepared from thermoplastic copolymer, mineral oil, tackifying resin, cellulose, anti-inflammatory substances and antioxidants, wherein: the mass ratio of the thermoplastic copolymer to the tackifying resin to the cellulose is 10-20:20-30:20-50. Further, the thermoplastic copolymer is at least one of a styrene-isoprene block copolymer (SIS), a styrene-butadiene block copolymer (SBS), a hydrogenated styrene-isoprene block copolymer (SEPS), a hydrogenated styrene-butadiene block copolymer (SEBS); Preferably, the thermoplastic copolymer is compounded by a styrene-isoprene block copolymer (SIS) and a hydrogenated styrene-butadiene block copolymer (SEBS), and the weight ratio of the styrene-isoprene block copolymer (SIS) to the hydrogenated styrene-butadiene block copolymer is 10-15:5. Further, the tackifying resin is at least one of rosin resin, hydrogenated rosin resin, C5 petroleum resin, C9 petroleum resin and C5/C9 copolymer resin, preferably C5 or C9 petroleum resin. Further, the cellulose is at least one of Methyl Cellulose (MC), hydroxypropyl methyl cellulose (HPMC), hydroxyethyl cellulose (HEC), carboxymethyl cellulose (CMC). Further, the anti-inflammatory substance is an ionic bactericide; The ionic bactericides comprise silver ion bactericides, copper ion bactericides and zinc ion bactericides, and preferably zirconium phosphate silver-loaded inorganic antibacterial powder. Further, the mineral oil is naphthenic oil or white mineral oil; The antioxidant is a hindered phenol antioxidant, and the hindered phenol antioxidant is one or two of a basf antioxidant rganox B and 2, 6-di-tert-butyl 4-methylphenol. Further, the hot melt adhesive comprises the following components in parts by weight: 10-20 parts of thermoplastic copolymer, 5-10 parts of mineral oil, 20-30 parts of tackifying resin, 20-50 parts of cellulose, 1-10 parts of anti-inflammatory substance and 0.1-0.5 part of antioxidant. The invention provides a preparation method of the hot melt adhesive for infant umbilicus plaster, which comprises the following steps: (A) Heating, melting and mixing part of tackifying resin with mineral oil and antioxidant uniformly to obtain an intermediate A; (B) Adding a thermoplastic copolymer into the intermediate A, heating and stirring until the thermoplastic copolymer is melted, then adding the rest tackifying resin, heating and stirring until the tackifying resin is melted, and then adding cellulose and an anti-inflammatory substance, heating and stirring until the thermoplastic copolymer is melted to obtain an intermediate B; (C) Cooling the intermediate B to obta