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CN-120771013-B - Mesenchymal stem cell exosome eye atomization drug delivery device

CN120771013BCN 120771013 BCN120771013 BCN 120771013BCN-120771013-B

Abstract

The invention belongs to the technical field of medical auxiliary instruments, and particularly relates to an eye atomization drug delivery device for a mesenchymal stem cell exosome, which comprises a machine body, a connecting pipe, a drug delivery mechanism and a disinfection mechanism, wherein an atomizer is arranged in the machine body, the connecting pipe is arranged on the outer wall of the atomizer, the drug delivery mechanism is arranged at one end of the connecting pipe far away from the machine body, the knob is arranged at the top of the machine body, and the disinfection mechanism is arranged at one side of the machine body far away from the drug delivery mechanism.

Inventors

  • LI XIA

Assignees

  • 江苏兴生生物医学工程有限公司

Dates

Publication Date
20260512
Application Date
20250724

Claims (8)

  1. 1. A mesenchymal stem cell exosome ocular nebulization drug delivery device comprising: the machine body (1) is characterized in that an atomizer (3) is arranged in the machine body (1); The connecting pipe (4) is arranged on the outer wall of the atomizer (3); The drug delivery mechanism (5), the drug delivery mechanism (5) is arranged at one end of the connecting pipe (4) far away from the machine body (1); the drug delivery mechanism (5) comprises: The Y-shaped pipe (501) is connected with one end of the connecting pipe (4) far away from the machine body (1); The housing (502), the said housing (502) is set up in the outer wall of Y-shaped pipe (501), the inner wall of the said housing (502) is cup jointed with outer wall of Y-shaped pipe (501); an adjusting component (506), wherein the adjusting component (506) is arranged on the inner wall of the housing (502), and the adjusting component (506) is used for adjusting the distance between the Y-shaped tube (501) and the human eye; The support assembly (505) is uniformly arranged on the inner wall of the housing (502), and the support assembly (505) is used for expanding upper eyelid and lower eyelid of a person; The adjustment assembly (506) includes: The two ends of the frame plate (5061) are in sliding connection with the inner wall of the housing (502), the inner wall of the frame plate (5061) is sleeved with the outer wall of the Y-shaped tube (501), and the frame plate (5061) is used for driving the medicine outlet end of the Y-shaped tube to be far away from human eyes; The adjustment assembly (506) further includes: a rubber ring (5062), wherein the rubber ring (5062) is arranged on the outer side of the middle part of the frame plate (5061), the rubber ring (5062) is used for contacting with the nose bridge, and the distance between the frame plate (5061) and the human eye is kept; The spring (5063) is symmetrically arranged on one side, far away from the rubber ring (5062), of the frame plate (5061), and the other end of the spring (5063) is connected with the inner wall of the housing (502).
  2. 2. The mesenchymal stem cell exosome ocular nebulization delivery device of claim 1, wherein: the mesenchymal stem cell exosome eye atomization administration device further comprises: the knob (2) is arranged at the top of the machine body (1); and the disinfection mechanism (6) is arranged at one side of the inside of the machine body (1) far away from the drug delivery mechanism (5).
  3. 3. The mesenchymal stem cell exosome ocular nebulization delivery device of claim 1, wherein the delivery mechanism (5) further comprises: The connecting sleeve (503) is arranged at the joint of the connecting pipe (4) and the Y-shaped pipe (501), and the connecting sleeve (503) is convenient for disassembling and cleaning the Y-shaped pipe (501) and the connecting pipe (4); The cover shell (502) is attached to the face of a person, so that atomized liquid medicine can be concentrated at the eyes of the person, dust is reduced to contact the eyes, and elliptical holes (504) are uniformly formed in the surface of the cover shell (502).
  4. 4. The mesenchymal stem cell exosome ocular nebulization delivery device of claim 2, wherein the disinfection mechanism (6) comprises: the cleaning tank (601) is arranged in the machine body (1) at one side far away from the drug delivery mechanism (5); The sponge plates (602) are symmetrically arranged on the inner wall of the cleaning tank (601); The cleaning rollers (603) are symmetrically arranged at the bottom of the inner wall of the cleaning tank (601), and the cleaning rollers (603) are used for cleaning and disinfecting the inner wall of the Y-shaped pipe (501).
  5. 5. The mesenchymal stem cell exosome ocular nebulization delivery device of claim 4, wherein the disinfection mechanism (6) further comprises: A disinfectant tank (609), wherein the disinfectant tank (609) is arranged at the bottom of the machine body (1); The air delivery pipe (604), the outer wall of the air delivery pipe (604) is connected with the outer wall of the disinfectant tank (609), one end of the air delivery pipe (604) far away from the disinfectant tank (609) is provided with a squeeze ball (605), and the squeeze ball (605) is used for inputting air into the disinfectant tank (609) in one direction; and the elastic sheet (610) is arranged on the inner wall of the disinfectant tank (609).
  6. 6. The mesenchymal stem cell exosome ocular nebulization delivery device of claim 5, wherein the disinfection mechanism (6) further comprises: a driving gear (608), wherein the driving gear (608) is arranged at the bottom of the machine body (1); The driven gear (607) is symmetrically arranged at the bottom of the machine body (1), the outer wall of the driven gear (607) is meshed with the outer wall of the driving gear (608), and the top of the driven gear (607) is in sliding connection with the bottom of the machine body (1); the drain pipe (606), drain pipe (606) symmetry sets up the top in antiseptic solution case (609), the outer wall that antiseptic solution case (609) one end was kept away from to drain pipe (606) cup joints with the inner wall of cleaning roller (603), the outer wall of drain pipe (606) cup joints with the inner wall of driven gear (607), and this drain pipe (606) are used for spraying antiseptic solution in Y-shaped pipe (501).
  7. 7. The mesenchymal stem cell exosome ocular aerosolization drug delivery device of claim 1, wherein the support assembly (505) comprises: The outer wall of the inserted link (5051) is sleeved with the inner wall of the elliptical hole (504), the inserted link (5051) can slide in the elliptical hole (504) and rotate by taking the wall of the elliptical hole (504) as a fulcrum, and the inserted link (5051) is provided with four parts; a pressing tab (5052) mounted to an end of the plunger (5051) remote from the housing (502).
  8. 8. The mesenchymal stem cell exosome ocular aerosolization drug delivery device of claim 7, wherein the support assembly (505) further comprises: a V-shaped rod (5053), the V-shaped rod (5053) being mounted at an end of the plunger (5051) remote from the pressing piece (5052), the V-shaped rod (5053) being disposed inside the housing (502); The arc pole (5054), arc pole (5054) set up the one end that inserted bar (5051) was kept away from in V word pole (5053), arc pole (5054) are used for separating the upper and lower eyelid of people's eye, arc pole (5054) are medical grade rubber material.

Description

Mesenchymal stem cell exosome eye atomization drug delivery device Technical Field The invention belongs to the technical field of medical auxiliary instruments, and particularly relates to a mesenchymal stem cell exosome eye atomization administration device. Background Mesenchymal stem cells are a precursor cell widely existing in various tissues and organs and having self-renewal and various differentiation potential, and the leading-edge regenerative medicine technology can realize regeneration of damaged tissues and organs by means of the mesenchymal stem cells or substitution treatment of tissues and organs required by in-vitro replication. The eye treatment medicine can respectively exert local treatment effect and systemic treatment effect through cornea way and conjunctival way, and at present, people adopt a mode of dripping eyedrops, which is not only troublesome, but also the mouth of the eyedrop bottle is not easy to align with eyeballs, and the eyedrops are difficult to enter eyes; The eye atomization administration is an innovative ophthalmic treatment method, and is characterized in that medicine is directly delivered to eyes in an atomization mode, atomized medicine particles are tiny, can penetrate through tear liquid layers and cornea epithelial layers on the surfaces of the eyes, directly act on lesion sites, can effectively improve the permeation and absorption of the medicine in the eyes, reduce the medicine waste and side effects, and improve the treatment effect. The existing ocular atomization administration mode is similar to the drip administration mode, ocular medicine water is atomized before administration, the distance between the nozzle and eyes is large, pollutants such as dust, smoke, bacteria and the like in the environment easily enter eyes along with atomized gas to cause infection or aggravate eye diseases, the distance between the nozzle and eyes is continuously reduced, and the atomizing nozzle is easily polluted. Disclosure of Invention Aiming at the defects of the prior art, the technical scheme adopted by the invention for solving the technical problems is that the mesenchymal stem cell exosome eye atomization drug delivery device comprises: The device comprises a machine body, wherein an atomizer is arranged in the machine body; The connecting pipe is arranged on the outer wall of the atomizer; the drug delivery mechanism is arranged at one end of the connecting pipe far away from the machine body; The drug delivery mechanism includes: The Y-shaped pipe is connected with one end of the connecting pipe far away from the machine body; the cover shell is arranged on the outer wall of the Y-shaped pipe, the inner wall of the cover shell is sleeved with the outer wall of the Y-shaped pipe, and the shape of the cover shell is similar to that of a diving mask, so that the cover shell can be well attached to a human face; the adjusting component is arranged on the inner wall of the housing and is used for adjusting the distance between the Y-shaped tube and the human eye; the support assembly is uniformly arranged on the inner wall of the housing and used for expanding upper and lower eyelid of a person. Further, the mesenchymal stem cell exosome eye atomization administration device further comprises: The knob is arranged at the top of the machine body; And the disinfection mechanism is arranged at one side of the body, which is far away from the drug delivery mechanism, inside the body. Further, the drug delivery mechanism further includes: the connecting sleeve is arranged at the joint of the connecting pipe and the Y-shaped pipe, and the connecting sleeve facilitates the disassembly and cleaning of the Y-shaped pipe and the connecting pipe; the cover shell is attached to the face of a person, so that atomized liquid medicine can be concentrated at the eyes of the person, dust is reduced to contact with the eyes, and elliptical holes are uniformly formed in the surface of the cover shell. Further, the disinfecting mechanism includes: the cleaning pool is arranged in the machine body at one side far away from the drug delivery mechanism; the sponge plates are symmetrically arranged on the inner wall of the cleaning pool; the cleaning rollers are symmetrically arranged at the bottom of the inner wall of the cleaning pool and are used for cleaning and disinfecting the inner wall of the Y-shaped pipe. Further, the disinfecting mechanism further comprises: the disinfectant tank is arranged at the bottom of the machine body; the outer wall of the gas transmission pipe is connected with the outer wall of the disinfectant tank, one end of the gas transmission pipe, which is far away from the disinfectant tank, is provided with an extrusion ball, and the extrusion ball is used for unidirectionally inputting air into the disinfectant tank; The elastic sheet is arranged on the inner wall of the disinfectant tank, and the air inlet end of the air delivery pipe is arranged below th