CN-121064438-B - Synthetic resin and adhesive for medical oxygen anesthesia mask, and preparation method and application thereof

Abstract

The invention discloses a synthetic resin for medical oxygen anesthetic mask, an adhesive and a preparation method and application thereof, wherein the synthetic resin is a siloxane intermediate with hydroxyl generated by KH-560 and KH-550 ring-opening reaction, and is prepared by modifying polyurethane, the adhesive comprises the following components, by weight, 100 parts of synthetic resin, 45-95 parts of reactive diluent and 4-14 parts of photoinitiator, the reactive diluent mainly comprises isobornyl acrylate, N-dimethylacrylamide, tetrahydrofuranacrylate and hydroxyethyl acrylate, and compared with the prior art, the adhesive prepared from the modified resin has the characteristics of quick solidification under the irradiation of an LED lamp, low energy consumption, convenience for automatic production, good surface dryness, good flexibility, constant temperature and constant humidity, no foaming, firm bonding of PC material cup and PVC material air bags of the oxygen mask, and the like.

Inventors

• LI BIAO
• LIU WEI

Assignees

• 广东鼎立森新材料股份有限公司

Dates

Publication Date

20260505

Application Date

20250922

Claims (10)

1. 1. A method for preparing synthetic resin for medical oxygen anesthetic mask, which is characterized by comprising the following steps: Step one, under the protection of nitrogen, mixing KH-560 and KH-550, heating to 50-70 ℃ to react for 0.3-1 h, and then heating to 80-100 ℃ to react for 3-5 h to obtain an intermediate C1 with tertiary amine and hydroxyl, wherein the molar ratio of KH-560 to KH-550 is 2:1; Placing diisocyanate and polyester polyol in a reactor with stirring and condensing reflux effects, reacting for 2-3 hours at 65-85 ℃, introducing nitrogen in the reaction process, and reacting to obtain an intermediate C2, wherein the added mass fraction of the diisocyanate is 18-32, and the added mass fraction of the polyester polyol is 51-75; step three, dropwise adding 1.6-3.1 parts by weight of chain extender, 0.5-1.2 parts by weight of intermediate C1 and a solvent for controlling the viscosity of a reaction system into a reactor, and continuously reacting to generate an intermediate C3; And fourthly, dropwise adding 5-14 parts by weight of (methyl) hydroxyl acrylate dissolved with a polymerization inhibitor into the reactor, keeping stirring in the dropwise adding process after the dropwise adding is finished, heating up for reaction after the dropwise adding is finished, measuring the NCO value of a reaction system during the reaction, and stopping the reaction when the NCO value of the system reaches a theoretical calculated value.
2. 2. The method for preparing a synthetic resin for medical oxygen anesthetic mask according to claim 1, wherein the diisocyanate is one or two of 4,4' -dicyclohexylmethane diisocyanate and isophorone diisocyanate.
3. 3. The method for preparing a synthetic resin for medical oxygen anesthetic mask according to claim 1, wherein the polyester polyol is one or more of 5400-1000,5400-1000a,5400-2000,5400-2000a,5400-2000C, HDPOL-4410, hdpol-4420 of the changxing materials industry.
4. 4. The method for preparing a synthetic resin for medical oxygen anesthetic mask according to claim 1, wherein the chain extender of the third step is 1, 4-butanediol.
5. 5. The method for preparing the synthetic resin for the medical oxygen anesthetic mask according to claim 1, wherein the hydroxy (meth) acrylate in the fourth step comprises one or more of hydroxy ethyl acrylate, hydroxy ethyl methacrylate, hydroxy propyl acrylate and hydroxy propyl methacrylate, and the polymerization inhibitor is one or more of hydroquinone, p-hydroxyanisole, 4-hydroxy-2, 6-tetramethylpiperidine-1-oxyl and 2, 6-tetramethylpiperidine-1-oxyl, and the amount of the polymerization inhibitor is 0.02-0.07% of the mass of the hydroxy (meth) acrylate.
6. 6. A synthetic resin produced by the method for producing a synthetic resin for a medical oxygen anesthetic mask according to any one of claims 1 to 5.
7. 7. An adhesive for medical oxygen anesthetic masks is characterized by comprising the following components in parts by weight: 45-95 parts of reactive diluent; 4-14 parts of photoinitiator; 100 parts of synthetic resin; Wherein the synthetic resin is the synthetic resin produced by the production method according to any one of claims 1 to 5 or the synthetic resin according to claim 6.
8. 8. The adhesive for medical oxygen anesthetic masks according to claim 7, wherein the reactive diluent comprises the following components, by mass, 12% -57% of isobornyl acrylate, 17% -56% of N, N-dimethylacrylamide, 13% -48% of tetrahydrofurane acrylate and 3% -20% of hydroxyethyl acrylate.
9. 9. An adhesive for medical oxygen anesthetic masks according to claim 7, wherein said photoinitiator comprises one or two of ethyl 2,4, 6-trimethylbenzoyl phenylphosphonate, 2,4, 6-trimethylbenzoyl-diphenyl phosphine oxide.
10. 10. Use of an adhesive for medical oxygen anesthetic masks according to any of the claims 7-9, wherein the adhesive is used for bonding PVC balloons and PC cups of medical oxygen anesthetic masks, and is cured by irradiation with LED lamps.

Description

Synthetic resin and adhesive for medical oxygen anesthesia mask, and preparation method and application thereof Technical Field The invention belongs to the technical field of adhesive preparation, and particularly relates to synthetic resin and adhesive for a medical oxygen anesthetic mask, and a preparation method and application thereof. Background The gas anesthetic mask is mainly used for assisting oxygen supply and anesthetic drug transmission in medical operation and generally comprises a face cup, an air bag, a connector and a fixing belt. Wherein, the cup (cup) is the main part contacting the mouth and nose of the patient, and is made of Polycarbonate (PC) or medical silica gel. The air bag is positioned at the edge of the face cup and is usually made of PVC or silica gel, and can be attached to the face after being inflated, so that air leakage is reduced. At present, in the assembly process of the medical oxygen anesthesia mask, the assembly of the PC-made cup and the PVC-made air bag is usually bonded and fixed by glue, namely, the PVC-made air bag is coated with an adhesive, then the PC-made cup is attached, and the fixing and sealing effects are achieved after the LED lamp is solidified. The adhesive is a key material in the assembly of the medical oxygen anesthetic mask, and the performance of the adhesive directly affects the safety and reliability of the product. The existing adhesive in the market has the problems that firstly, the photo-curing speed is low, the curing is required to be completed in 5 seconds when an LED lamp is irradiated, secondly, the flexibility is poor, the PC face cup and the PVC air bag adhesive layer of the oxygen mask are easy to crack after being cured, thirdly, the weather resistance is poor, the adhesive layer has bubbles after constant temperature and humidity, the adhesion is unstable, and fourthly, the adhesion strength is insufficient, so that the PC face cup and the PVC air bag are easy to fall off. The prior art has various adhesive products, for example, chinese patent publication No. CN109929503A discloses a low-odor high-toughness ultraviolet curing adhesive and a preparation method thereof. The adhesive has the characteristics of small product smell, high toughness, ethylene oxide sterilization resistance, wet heat aging resistance, qualified biological evaluation performance and capability of being used for adhesion among common high polymer materials such as PVC, PC, ABS, K-resin and the like for medical appliances. Experiments prove that the adhesive prepared by the patent can not achieve the effect of rapid solidification under the radiation of the LED lamp. Also for example, chinese patent publication No. CN111073522a discloses an epoxy adhesive dedicated for UV light curing PVC substrate bonding. The adhesive has strong adhesion to the PVC film, and the epoxy resin HE20 and polyurethane modified epoxy resin are used for replacing part of alicyclic epoxy resin, but the epoxy adhesive has insufficient flexibility and larger brittleness, and can not meet the adhesion effect of the face cup made of the PC material of the medical mask and the air bag made of the PVC material. Also, for example, chinese patent publication No. CN104178038 discloses an instant dry solvent-free adhesive for PVC pipe bonding. The adhesive has the advantages of good moist heat resistance, good ageing resistance, good toughness, good migration resistance, high bonding strength to PVC and the like. The main raw material cyanoacrylate used herein has certain toxicity to human body and is used with cautions in the medical field. In view of the above, the present invention proposes a synthetic resin for medical oxygen anesthetic mask, an adhesive, and a preparation method and application thereof, to solve the above problems. Disclosure of Invention In view of the shortcomings of the prior art, a first object of the present invention is to provide a synthetic resin for medical oxygen anesthetic masks, which combines the advantages of strong adhesion, weather resistance and the like of organosilicon, polyurethane and acrylic ester. A synthetic resin for medical oxygen anesthetic mask has a structural formula as shown in formula I: in the formula I, R 1 represents any one of the following structural formulas; R 2 represents a1, 4-butanediol alkyl segment, R 3 represents an acrylic acid alkyl segment, and R 4 represents an alkyl group having 1 to 20 carbon atoms. Aiming at the defects of the prior art, the second aim of the invention is to provide a preparation method of synthetic resin for medical oxygen anesthetic masks, KH-560 and KH-550 are subjected to ring-opening reaction according to a molar ratio of 2:1 to generate a siloxane intermediate with hydroxyl, and polyurethane is used for modifying to prepare the adhesive resin for medical oxygen anesthetic masks. A method for preparing synthetic resin for medical oxygen anesthetic mask, comprising the following steps: step one,