CN-121288183-B - Physical intelligent artificial heart and control method thereof

CN121288183BCN 121288183 BCN121288183 BCN 121288183BCN-121288183-B

Abstract

The invention relates to the technical field of artificial hearts, in particular to a physical intelligent artificial heart and a control method thereof, wherein an LCE (liquid crystal display) balloon with a double-layer structure is formed by adopting LCE materials, circuits for winding the LCE balloon are respectively added into two layers of LCE films, power is provided for beating of the LCE balloon based on an electrothermal effect, and meanwhile, periodic circulation of pumping blood into or pumping out of a left ventricle is realized by combining an aortic valve one-way valve and two cusp one-way valves, so that the dynamic beating characteristics of the left ventricle participating in a human blood circulation system are simulated. The invention has the advantages of high efficiency and convenience in analyzing the chaotic self-excited beating of the heart through theoretical simulation, can quickly simulate the dynamic beating characteristics of the left ventricle participating in the blood circulation system of a human body compared with experimental and observing methods, can promote the application of chaotic dynamics in the fields of artificial hearts, medical appliances and the like, and provides theoretical support for early diagnosis of cardiovascular diseases.

Inventors

Xu Peibao
ZHU HONGWEI
LI KAI
DAI YUNTONG
SUN XIN
YU YONG
ZHAO JUN

Assignees

安徽建筑大学

Dates

Publication Date: 20260508
Application Date: 20251014

Claims (8)

1. The physical intelligent artificial heart comprises a bionic left ventricle (1) manufactured through a mold forming process and a connecting and fixing device (2) used for internally installing the bionic left ventricle (1) and firmly, and is characterized in that the bionic left ventricle (1) comprises an LCE balloon (10) with a double-layer structure formed by a first LCE film (11) and a second LCE film (12); The physical intelligent artificial heart also comprises a body circulation system (3) which is arranged on the LCE balloon (10) and is used for pumping blood therein and inputting the blood therein again to realize periodic circulation, and a power driving system (4) which is used for promoting the LCE balloon (10) to shrink inwards and recover gradually based on periodic electrothermal stimulation; The power driving system (4) comprises an electrothermal stimulation circuit (41) which is embedded or wound on the first LCE film (11) and the second LCE film (12), a contact point (42) which is arranged on the connecting and fixing device (2) and an external power supply, when the LCE balloon (10) is expanded and touches the contact point (42), the circuit is electrified, the LCE balloon (10) is contracted inwards by the electrothermal effect, when the LCE balloon (10) is separated from the contact point (42), the circuit is powered off, and the LCE balloon (10) stops contracting and gradually recovers; The connecting and fixing device (2) comprises an outer main body supporting device (21), an arc-shaped bracket (22) used for fixedly arranging the LCE balloon (10) is arranged in the outer main body supporting device (21), a fixing beam (23) used for installing a contact point (42) is arranged at the top in the outer main body supporting device (21), and the contact point (42) is located right above the LCE balloon (10).
2. The physical intelligent artificial heart according to claim 1, wherein the systemic circulation system (3) comprises an aorta (31) and a mitral valve (32) which are symmetrically arranged at two sides of the LCE balloon (10) and are respectively communicated with the aorta (31) and the mitral valve (32), and a blood circulation device (35) which is communicated with the aorta (31) and the mitral valve (32), an aortic valve one-way valve (33) and a two-cusp one-way valve (34) are respectively arranged at one ends of the aorta (31) and the mitral valve (32) close to the LCE balloon (10), blood in the LCE balloon (10) is pumped into the main artery (31) through the aortic valve one-way valve (33), and then is conveyed into the mitral valve (32) through the blood circulation device (35), and finally flows into the LCE balloon (10) through the two-cusp one-way valve (34).
3. A control method applied to the physical intelligent artificial heart according to any one of claims 1-2, characterized in that the method comprises the following steps: S1, defining chest pressure And according to chest pressure Calculating ventricular pressure as an introduced variable affecting simulated left ventricular beat ; S2, determining the temperature difference of the LCE balloon in an autonomous power supply or power failure state And solving electrothermal driving shrinkage strain of bionic left ventricle ; S3, driving shrinkage strain through electric heat Calculating principal stress in bionic left ventricle plane And based on principal stress Calculating Laplacian stress of bionic left ventricle ; S4, based on ventricular pressure Laplace stress Establishing a dynamic control equation for realizing autonomous beating of the artificial heart under the action of electric heat; S5, solving a dynamic control equation by using a fourth-order Longge-Kutta method to obtain the radius of the bionic left ventricle for regulating and controlling the autonomous beating mode of the artificial heart According to radius Judging whether the bionic left ventricle is in an electrified state or not, and updating the temperature difference according to the judging result Is a state of (2).
4. A control method according to claim 3, wherein the chest pressure Chest pressure caused by contraction and expansion of respiratory muscle groups such as diaphragm and intercostal muscles is expressed as follows: ; in the formula, A is the maximum active pressure; Representing respiratory rate, which is related to respiratory cycle The relation of (2) is that ; Self-excitation beating time of the bionic left ventricle; In determining chest pressure On the basis of (a) obtaining variable ventricular pressure by calculation The expression is: ; in the formula, Ventricular volume that is the bionic left ventricle; 、 the unstressed ventricular volumes at end diastole and end systole, respectively.
5. A control method according to claim 3, characterized in that in step S2, the specific procedure comprises the steps of: s21, establishing an electric Joule heat conduction model for representing heat generated by current through the LCE balloon based on Joule law, wherein the expression is as follows: ; ; ; in the formula, Characteristic time for heat exchange of LCE membrane with ambient; the limiting temperature difference of the LCE film under the long-term electrifying condition is obtained; For electrical heating intensity, the heat generated per second by the passage of current through the LCE film; is specific heat capacity; Is the heat transfer coefficient; is the temperature difference; s22, determining temperature difference of LCE balloon in autonomous power supply or power failure state based on electric Joule heat conduction model The method comprises the following steps: Temperature difference The state under autonomous power supply is: ; Temperature difference The state under power outage is: ; in the formula, Radius of bionic left ventricle; Meaning that blood is injected into the unstressed LCE saccule until the radius of the bionic left ventricle reaches a critical state; s23, according to the temperature difference of the LCE balloon in an autonomous power supply or power failure state Calculation of electrothermal drive contraction strain of bionic left ventricle The calculation formula is as follows: ; in the formula, Is the coefficient of contraction of the LCE balloon.
6. A control method according to claim 3, characterized in that in step S3, the specific procedure comprises: calculating principal stress in bionic left ventricle plane based on plane stress assumption The calculation formula is as follows: ; in the formula, Radius of bionic left ventricle; elastic modulus which is the material structure of the LCE balloon itself; Is poisson's ratio; representing the initial radius of the LCE balloon in the absence of stress; According to principal stress Calculating Laplacian stress generated by bionic left ventricle in autonomous power supply or power off state The calculation formula is as follows: ; in the formula, Indicating the thickness of the LCE balloon.
7. The control method according to claim 6, wherein the expression of the dynamic control equation is: ; Wherein: ; ; in the formula, Atmospheric pressure applied to the bionic left ventricle; The thickness of the LCE balloon is indicated, Representing the volume of the material structure of the LCE balloon itself; Is the density of LCE balloons; And Radial velocity and acceleration of the left ventricle, respectively; representing a radial damping coefficient associated with left ventricular deformation; one-way valves disposed in the aortic and mitral veins, respectively; resistance to the mitral valve vein; Blood flow for the aorta; Is bionic left ventricular pressure; elastic modulus which is the material structure of the LCE balloon itself.
8. The control method according to claim 7, characterized in that in step S5, the specific process includes the steps of: s51, ventricular volume based on bionic left ventricle Aortic blood flow Pressure of active pulse Bionic left ventricular pressure The coupling relation between the two components is established, and a coupling circulation system of four state equations is established in the bionic left ventricle, namely: ; ; ; ; in the formula, Is the aortic pressure; resistance to the aortic valve; Is a characteristic resistance of the aorta; comprehensive resistance of the arterial system; Is the overall compliance of the arterial system; is the overall compliance of the pulmonary venous system; is the blood flow inertia of the aorta; s52, will Substituting the non-dimensionality processing into a state equation contained in the coupling circulation system, and obtaining: ; ; ; s53, solving a state equation after simultaneous dimensionless treatment by using a fourth-order Longg-Kutta method to obtain the radius of the bionic left ventricle ; S54, according to radius Judging whether the bionic left ventricle is in an electrified state or not; If it is The bionic left ventricle is in an electrified state, so that the LCE saccule is contracted, and the two-cusp valve one-way valve Maintain the closed state when the ventricular pressure is Greater than the aortic pressure When the valve is opened, the valve is opened Opening, wherein blood is pumped out of the bionic left ventricle; If it is The bionic left ventricle is in a power-off state, so that the LCE saccule is inflated, and the aortic valve is provided with a one-way valve Maintain the closed state when the ventricular pressure is Below the pressure of atrium, two cusp valve one-way valve Opening, blood flows from atrium into bionic left ventricle, and calculating updated ventricular pressure according to current state 。

Description

Physical intelligent artificial heart and control method thereof Technical Field The invention relates to the technical field of artificial hearts, in particular to a physical intelligent artificial heart and a control method thereof. Background Chaos phenomenon is ubiquitous in our life, such as banners flying in the wind, drip faucets, chemical reactions, biological systems, etc. Chaos is a necessary condition for proper operation in some cases. In the circulatory system of the human body, the left ventricle plays a vital role therein, transporting oxygenated blood from the heart to the body. Studies have shown that the healthy cardiovascular system is nonlinear and complex. Circulatory diseases may manifest as a reduction in confusion or a greater extent of this form of non-linear dynamics. In recent years, scholars have been increasingly focusing on self-sustaining chaotic systems based on Liquid Crystal Elastomer (LCE) materials. The system may better simulate natural motion patterns, particularly in heart-related applications. Therefore, the research of the self-maintenance chaotic system based on LCE is helpful for heart and brain chaotic analysis, cardiovascular disease prevention and treatment and bionics. Currently, with the explosive development of active materials, high attention is paid to self-vibration systems based on active materials. However, artificial hearts constructed based on self-vibration systems, when subjected to theoretical simulation analysis of self-excited beating, cannot absorb energy from the external environment to compensate for damping dissipation to maintain continuous beating, and have poor self-regulation ability. In addition, the common methods for heart beat analysis comprise a time domain analysis method and a morphological analysis method, and the two analysis methods have insufficient sensitivity to heart beat analysis and are influenced by individual differences, so that efficient and convenient theoretical analysis is difficult to carry out, and therefore, how to realize the efficient and convenient theoretical analysis method is a problem to be solved. Disclosure of Invention The invention provides a physical intelligent artificial heart and a control method thereof, which are used for solving the technical problems in the background art. In order to solve the technical problems, the invention provides the technical scheme that the physical intelligent artificial heart comprises a bionic left ventricle and a connecting and fixing device, wherein the bionic left ventricle is manufactured through a mold forming process and is used for internally installing the bionic left ventricle and is firmly connected with the fixing device, and the bionic left ventricle comprises an LCE balloon with a double-layer structure formed by a first LCE film and a second LCE film; The physical intelligent artificial heart also comprises a body circulation system which is arranged on the LCE balloon and used for pumping blood therein and inputting the blood therein again to realize periodic circulation, and a power driving system which is used for promoting the LCE balloon to shrink inwards and recover gradually based on periodic electrothermal stimulation. Further, the systemic circulation system comprises an aorta and a mitral valve which are symmetrically arranged at two sides of the LCE balloon and are respectively communicated with the aorta and the mitral valve, and a blood circulation device which is communicated with the aorta and the mitral valve, wherein an aortic valve one-way valve and a two-cusp one-way valve are respectively arranged at one end of the aorta and the mitral valve, which is close to the LCE balloon, blood in the LCE balloon is pumped into the main artery through the aortic valve one-way valve, and then is conveyed into the mitral valve through the blood circulation device, and finally flows into the LCE balloon through the two-cusp one-way valve. Further, the power driving system comprises an electric heating stimulation circuit which is embedded or wound on the first LCE film and the second LCE film, a contact point which is arranged on the connecting and fixing device and an external power supply, when the LCE balloon is inflated and contacted with the contact point, the circuit is electrified, the LCE balloon is contracted inwards by the electric heating effect, when the LCE balloon is separated from the contact point, the circuit is powered off, and the LCE balloon stops contracting and gradually recovers. Further, the connection fixing device comprises an outer main body supporting device, an arc-shaped bracket used for fixedly arranging the LCE balloon is arranged in the outer main body supporting device, a fixing beam used for installing a contact point is arranged at the top in the outer main body supporting device, and the contact point is located right above the LCE balloon. Further, the invention provides a control method of the physical intelli