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CN-121336831-B - Sustained release preparation for preventing and treating meloidogyne diseases in saline-alkali soil and preparation method thereof

CN121336831BCN 121336831 BCN121336831 BCN 121336831BCN-121336831-B

Abstract

The application relates to the technical field of environment-responsive pesticide preparations, and in particular discloses a slow-release preparation for controlling meloidogyne diseases in saline-alkali soil and a preparation method thereof. The slow release preparation for preventing and treating melon root knot nematode disease in saline-alkali soil comprises, by mass, 55-57% of 30% fosthiazate microcapsule suspension, 19-21% of 15% fluopyram microcapsule suspension, 4-6% of response components, 5-7% of surfactants, 0.5-0.6% of thickening agents, 0.03-0.04% of preservatives, 0.01-0.02% of defoaming agents and the balance of water, and in addition, the preparation method of the application has the advantages of realizing directional release and synergistic effect of fosthiazate and fluopyram compound agents and adapting to high pH environments of saline-alkali soil.

Inventors

  • SONG WENYONG
  • HAN MEI
  • ZHANG SHIQIANG
  • LI YUNHENG
  • MENG LINGBO

Assignees

  • 济南一农化工有限公司

Dates

Publication Date
20260508
Application Date
20251218

Claims (6)

  1. 1. The slow release preparation for preventing and treating melon root knot nematode disease in saline-alkali soil is characterized by comprising the following raw materials, by mass, 55-57% of 30% of fosthiazate microcapsule suspension, 19-21% of 15% of fluopyram microcapsule suspension, 4-6% of response components, 5-7% of surfactants, 0.5-0.6% of thickening agents, 0.03-0.04% of preservatives, 0.01-0.02% of antifoaming agents, the balance of water, the wall thickness of fosthiazate microcapsules is more than or equal to 5 mu m, and the wall thickness of fluopyram microcapsules is less than or equal to 0.5 mu m; The response component comprises the following raw materials, by mass, 85-90% of wood vinegar fraction, 2-3% of fatty alcohol ether phosphate, 2-3% of EO-PO block polyether, 0.5-0.6% of polyvinyl alcohol, 3-4% of ethylene glycol and the balance of water; the preparation method of the response component comprises the following steps of mixing wood vinegar fraction with EO-PO block polyether, fully stirring to form a uniform solution, adding the uniform solution into water dissolved with fatty alcohol ether phosphate, shearing and emulsifying to form emulsion, and adding polyvinyl alcohol and ethylene glycol to prepare the response component.
  2. 2. The slow-release preparation for preventing and treating meloidogyne diseases in saline-alkali soil, which is characterized by comprising, by mass, 4-6% of diphenylmethane diisocyanate, 1.5-2.5% of ethylenediamine, 30% of fosthiazate, 1-2% of lignosulfonate, 4-6% of sodium methylenedinaphthyl sulfonate and the balance of water.
  3. 3. The slow release preparation for preventing and treating meloidogyne diseases in saline and alkaline land according to claim 2, wherein the preparation method of the 30% fosthiazate microcapsule suspension is characterized by comprising the following steps of respectively metering and crushing fosthiazate, diphenylmethane diisocyanate, lignosulfonate and water, sequentially adding into a mixing kettle, stirring, heating to 60-65 ℃ for full dissolution, stirring, cooling, dropwise adding ethylenediamine while stirring, adding sodium methylenedinaphthyl sulfonate after the dropwise adding is completed, and regulating the pH to 6-7 to obtain the 30% fosthiazate microcapsule suspension.
  4. 4. The slow-release preparation for preventing and treating meloidogyne disease in saline-alkali soil, which is characterized by comprising, by mass, 4-5% of gelatin, 4-5% of acacia, 15% of fluopyram, 44-46% of toluene, 19-21% of dimethyl sulfoxide and the balance of water.
  5. 5. The slow-release preparation for preventing and treating meloidogyne disease in saline-alkali soil is characterized by comprising the following steps of mixing Arabic gum with water to prepare 10-50% Arabic gum pre-dissolved solution for standby, mixing gelatin with water to prepare 20-70% gelatin pre-dissolved solution for standby, mixing fluopyram, toluene, dimethyl sulfoxide and the rest water, homogenizing under high pressure to form uniform emulsion, dripping Arabic gum pre-dissolved solution, dripping gelatin pre-dissolved solution under high pressure homogenizing condition, cooling, and regulating pH to 6-7 to prepare 15% fluopyram micro-capsule suspension.
  6. 6. The preparation method of the slow-release preparation for controlling the meloidogyne disease in the saline-alkali soil is characterized by comprising the following steps of mixing 30% of fosthiazate microcapsule suspension, 15% of fluopyram microcapsule suspension and response components, adding a surfactant, stirring uniformly, and sequentially adding a thickening agent, a defoaming agent, water and a preservative to prepare the slow-release preparation for controlling the meloidogyne disease in the saline-alkali soil.

Description

Sustained release preparation for preventing and treating meloidogyne diseases in saline-alkali soil and preparation method thereof Technical Field The application relates to the technical field of environment-responsive pesticide preparations, in particular to a slow-release preparation for controlling meloidogyne diseases in saline-alkali soil and a preparation method thereof. Background In the technical field of environment-responsive pesticide preparations, with the continuous development of agriculture, the requirements for pesticide preparations are increasingly increasing. Especially in the special environment such as saline-alkali soil, the crops face the threat of various diseases and insect pests such as meloidogyne diseases, and an effective control means is important to guaranteeing the yield and quality of the crops. Meanwhile, people pay more attention to the safety, stability and environmental friendliness of pesticide preparations, which promotes the continuous innovation and development of related technologies so as to meet the actual demands of agricultural production. In the past, aiming at the prevention and treatment of melon root knot nematode diseases in alkaline soil, various modes are often adopted, for example, a fosthiazate and fluopyram compound preparation is generally encapsulated by a single capsule wall material, so that two active components are synchronously released in the alkaline soil, or fluopyram and hymexazol are compounded, and the prevention and treatment spectrum is enlarged. Or the combination of abamectin, fosthiazate and garlic oil is used, and the soil permeability is improved by means of fumigation. Or the fosthiazate single agent is used for preventing and treating. Or adopting a compounding scheme of abamectin, parathion and the like. Or a compound product of the paecilomyces lilacinus agent, and further comprises a dosage form such as emulsifiable concentrate, a soluble agent and the like, a granule and the like. However, the prior art has significant drawbacks. The conventional fosthiazate and fluopyram compound preparation is encapsulated by a single capsule wall material, so that the risk of causing phytotoxicity due to early release of high-volatility fosthiazate is caused, and the slow release requirement of fluopyram cannot be met. Meanwhile, the existing scheme is not optimized for the high pH environment of the saline-alkali soil, the prevention effect is reduced, and the soil improvement function is lacked. Other compounding schemes also have the problems of unpublished co-toxicity coefficient, undefined synergistic mechanism, unresolved stability problem of high volatile components, easy degradation of partial components, obvious resistance to specific nematodes, short duration of action, soil pollution and exceeding of agricultural product residues, inhibited microbial activity, easy initiation of phytotoxicity, inapplicability to drip irrigation systems, unstable release rate, low inhibition rate to egg hatching and the like. Disclosure of Invention The application provides a slow release preparation for controlling melon root knot nematode disease in saline-alkali soil and a preparation method thereof, in order to realize directional release and synergistic effect of a fosthiazate and fluopyram compound medicament and adapt to the high-pH environment of the saline-alkali soil. In a first aspect, the application provides a sustained release preparation for preventing and treating meloidogyne diseases in saline-alkali soil, which adopts the following technical scheme: the slow release preparation for preventing and treating melon root knot nematode disease in saline-alkali soil comprises, by mass, 55-57% of 30% of fosthiazate microcapsule suspension, 19-21% of 15% of fluopyram microcapsule suspension, 4-6% of response components, 5-7% of surfactants, 0.5-0.6% of thickeners, 0.03-0.04% of preservatives, 0.01-0.02% of defoamers and the balance of water, wherein the response components comprise, by mass, 85-90% of pyroligneous liquor fraction, 2-3% of fatty alcohol ether phosphate, 2-3% of EO-PO block polyether, 0.5-0.6% of polyvinyl alcohol, 3-4% of ethylene glycol and the balance of water. By adopting the technical scheme, the wall thickness of the fosthiazate microcapsule is thicker, after the two microcapsules are compounded by the thinner wall thickness of the fluopyram microcapsule, the gradient release of fosthiazate and fluopyram can be realized, the fluopyram can be released in advance, the effective control concentration is quickly established, then the fosthiazate microcapsule presents the slow release characteristic, the long-term slow release control is realized, the response component can enable the slow release preparation to maintain the acidic environment, the stability of storage is favorable, and after the fosthiazate microcapsule is released, the alkalinity of soil can be preferentially neutralized, the rupture release of the flu