CN-121400449-B - Special medical fertilizer for metalaxyl-M and azoxystrobin, and preparation method and application thereof

Abstract

The invention discloses a special medical fertilizer of metalaxyl-M and azoxystrobin, and a preparation method and application thereof, and belongs to the technical field of special medical fertilizers. The special pesticide fertilizer for the metalaxyl-M comprises, by weight, 0.1-2% of the metalaxyl-M, 0.1-2% of the azoxystrobin, 1-10% of a microbial agent metabolite, 0.5-1.5% of sophorolipid, 0.2-3% of ethylene glycol, 5-20% of nitrogen phosphorus potassium, 0.1-2% of calcium, 0.1-2% of magnesium and the balance of a water-soluble organic filler. The microbial inoculum metabolite, sophorolipid, metalaxyl-M and azoxystrobin prepared by the specific method have synergistic effect, so that the purpose of pesticide fertilizer application reduction and synergy is realized.

Inventors

• ZHANG SHIQIAN
• DU ZHANTAO
• WANG KAIFANG
• SHI PUTAO
• JING HUI
• CAO MINGZHANG
• ZHANG DINGBING
• LI GUANGZE
• GU KAIPING
• YANG LIPING
• ZHANG HUADONG
• SONG CANCAN
• FENG JIARU
• LI QI

Assignees

• 深圳诺普信作物科学股份有限公司
• 陕西标正作物科学有限公司

Dates

Publication Date

20260508

Application Date

20251226

Claims (6)

1. 1. The special medical fertilizer for metalaxyl-M and azoxystrobin is characterized by comprising, by weight, 0.1-2% of metalaxyl-M, 0.1-2% of azoxystrobin, 1-10% of microbial inoculum metabolite, 0.5-1.5% of sophorolipid, 0.2-3% of ethylene glycol, 5.2-24% of fertilizer and the balance of water-soluble organic matter filler, wherein the water-soluble organic matter filler is potassium fulvate; the fertilizer comprises 2.5-10% of nitrogen element fertilizer, 2.5-10% of phosphorus-potassium element fertilizer, 0.1-2% of calcium element fertilizer and 0.1-2% of magnesium element fertilizer; The nitrogen element fertilizer is urea, the phosphorus-potassium element fertilizer is monopotassium phosphate, the calcium element fertilizer is calcium nitrate, and the magnesium element fertilizer is magnesium sulfate; The microbial inoculum metabolite is prepared by the following method: The method comprises the steps of 1, activating Trichoderma harzianum conidium, inoculating and culturing to obtain a seed solution, adding the seed solution into a sterilized fermentation medium according to the addition amount accounting for 7% of the weight of the fermentation medium, and fermenting to obtain Trichoderma harzianum fermentation liquid, wherein the fermentation medium comprises 2.5-3.5 g/L of sucrose, 0.5-1.5 g/L of peptone, 0.5-1.0 g/L of yeast extract, 0.2-0.8 g/L of ammonium sulfate, 0.35-1.0 g/L of potassium dihydrogen phosphate, 0.35-1.0 g/L of sodium dihydrogen phosphate, 0.25-0.60 g/L of calcium carbonate and 7.0-7.5 of pH value; step 2, filtering the fermentation liquor through a filter membrane to obtain filtrate; Step 3, concentrating the filtrate at 40-45 ℃ under reduced pressure, and then freeze-drying to obtain powdery metabolites; Step 4, uniformly mixing the powdery metabolite, ascorbic acid and sodium lignin sulfonate, wherein the addition amount of the ascorbic acid is 1% of the mass of the powdery metabolite, and the addition amount of the sodium lignin sulfonate is 2% of the mass of the powdery metabolite; and 5, mixing the mixture with water to obtain the microbial inoculum metabolite with the concentration of 1-10wt%.
2. 2. The special pesticide fertilizer for metalaxyl-M and azoxystrobin according to claim 1, wherein in the step 1, the fermentation condition is that the temperature is 28-30 ℃, the ventilation amount is 0.5-1.0 vvm, the stirring speed is 150-200 rpm, and the culture is carried out for 3-7 days.
3. 3. The preparation method of the special medical fertilizer of metalaxyl-M and azoxystrobin as claimed in claim 1 or 2, which is characterized by comprising the following steps: (1) Preparing a microbial inoculum metabolite; (2) Uniformly mixing the microbial inoculum metabolite, sophorolipid and glycol, then adding metalaxyl-M, and uniformly mixing; (3) Adding azoxystrobin and fertilizer into the step (2), and uniformly mixing to obtain a mixed solution; (4) And adding water-soluble organic filler into the roller, adding the mixed solution in a rotating state, drying at 50-60 ℃, and cooling by countercurrent cold air at 15-20 ℃.
4. 4. Application of a special medical fertilizer of metalaxyl-M and azoxystrobin according to claim 1 or 2 in controlling soil-borne diseases of crops in fields, channels and areas and Chinese herbal medicine areas.
5. 5. The use according to claim 4, wherein the special medical fertilizer is directly applied by broadcasting or dissolved and applied by adding water.
6. 6. The application of claim 5, wherein the special pesticide fertilizer is used in an amount of 2-10 kg/mu.

Description

Special medical fertilizer for metalaxyl-M and azoxystrobin, and preparation method and application thereof Technical Field The invention relates to the technical field of special medical fertilizers, and in particular provides a special medical fertilizer of metalaxyl-M and azoxystrobin, and a preparation method and application thereof. Background The metalaxyl-M is a phenylamide systemic bactericide, is a high-efficiency isomer of metalaxyl, and has good control effect on crop diseases of vegetables, fruit trees, tobacco, oil, cotton, grains, chinese herbal medicines and the like caused by lower fungi such as downy mildew, phytophthora, pythium and the like. Azoxystrobin is a methoxy acrylic ester systemic fungicide, is efficient and broad-spectrum, is effective to almost all higher and lower fungal diseases, and can be used for leaf spraying and soil treatment. The special pesticide fertilizer is innovated and upgraded by the development of pesticide granules, and related reports of the special pesticide fertilizer exist in the prior art. The special pesticide fertilizer is prepared into a slow release formulation (such as CN 113372163A) to enable crops to slowly release pesticide and fertilizer components, prolong the action period of the pesticide and fertilizer, and achieve the purpose of reducing the application and enhancing the efficiency, and the anti-tumor drug and the Chinese herbal medicine (such as CN 116172021A) which are used by human bodies and interfere with the synthesis of plant pathogenic bacteria RNA are added into the granular pesticide fertilizer to achieve the effect of killing pathogenic bacteria and reducing the resistance of pathogenic bacteria, so that the application and the enhancing effect are reduced. However, the second mode of reducing and enhancing the application has a certain problem that the systemic property and the retention period of human medicine in crops are unknown, the potential risks of food chain enrichment and food safety exist, and the problems of soil pollution and runoff water pollution exist when the human medicine antibiotics are directly applied to soil. Unlike human medicine, the agricultural microbial agent is widely accepted in agriculture for its safety and effectiveness, has the functions of secreting antibiotics and various active enzymes, can inhibit or kill pathogenic bacteria, reduce disease occurrence and strengthen crop stress resistance, can effectively prevent crop physiological disease occurrence, can secrete cytokinin, auxin and other active substances, stimulates, regulates and promotes crop growth and development, and is favorable for crop yield increase. The microbial agent plays an important role in preventing and controlling crop rhizosphere diseases, promoting crop yield and improving crop stress resistance in microbial agent metabolites secreted in fields. However, the coexistence of the agricultural microbial agent as the microscopic living microorganism and the pesticide is always an industrial problem (pesticide components have the functions of inhibiting and inactivating the microbial agent), and the recycling utilization of microbial agent metabolites after fermentation of the microbial agent is always to be broken through, so that the direct discharge has an influence on the environment. Disclosure of Invention In order to solve the problems in the prior art, the invention provides a special pesticide fertilizer of metalaxyl-M and azoxystrobin, a preparation method and application thereof, the microbial inoculum metabolite and sophorolipid of the invention cooperate with pesticide components to prevent and treat plant rhizosphere diseases (inhibit or kill pathogenic bacteria), the purpose of pesticide application reduction and synergy is achieved, in addition, the fertilizer components can be cooperated, the fertilizer components can be absorbed and utilized through active substances while the fertilizer components contain nutrient substances required by crops, the growth and yield increase of the crops are promoted, and the purpose of fertilizer application reduction and synergy is achieved. In order to solve the technical problems, the invention provides the following technical scheme: On the one hand, the invention provides a special medical fertilizer of metalaxyl-M and azoxystrobin, which comprises, by weight, 0.1-2% of metalaxyl-M, 0.1-2% of azoxystrobin, 1-10% of microbial inoculum metabolite, 0.5-1.5% of sophorolipid, 0.2-3% of glycol, 5.2-24% of fertilizer and the balance of water-soluble organic filler, wherein the water-soluble organic filler is potassium fulvate. The fertilizer comprises 2.5-10% of nitrogen element fertilizer, 2.5-10% of phosphorus-potassium element fertilizer, 0.1-2% of calcium element fertilizer and 0.1-2% of magnesium element fertilizer; the nitrogen element fertilizer is urea, the phosphorus-potassium element fertilizer is monopotassium phosphate, the calcium element fertilizer is calcium nit