CN-121401612-B - Visual control method for optical power density and safety on retina

CN121401612BCN 121401612 BCN121401612 BCN 121401612BCN-121401612-B

Abstract

The invention provides a visual control method for optical power density and safety on retina, which comprises the steps of irradiating reference light on a simulated eye, collecting optical reference data of cornea area of the simulated eye and retina area of the simulated eye, irradiating light to be tested on the simulated eye, collecting optical test data of cornea area of the simulated eye and retina area of the simulated eye, determining associated data sets of retina area of the simulated eye under different diopters based on an inserting lens optometry, and adjusting the emergent equipment according to the type of the emergent equipment of the light to be tested, the optical reference data, the optical test data and the associated data sets. The invention solves the problem that the prior art lacks a method for measuring and controlling the retina optical power density and the light spot size in RLRL red light treatment technology.

Inventors

HU ZHANYU
FANG WENQING
LIAO CHAO
CHEN TAIYANG
WANG GUANGXU
YANG CHAOPU

Assignees

南昌大学
南昌实验室

Dates

Publication Date: 20260512
Application Date: 20251226

Claims (8)

1. A method of visually controlling optical power density and safety on the retina, the method comprising: illuminating reference light on a simulated eye and collecting optical reference data of a cornea region of the simulated eye and a retina region of the simulated eye, wherein the reference light is red sunlight; illuminating light to be detected on a simulated eye, and collecting optical test data of a cornea area of the simulated eye and a retina area of the simulated eye; determining a correlation data set of retina areas of the simulated eye at different diopters based on an insert refraction method; adjusting the emergent equipment according to the type of the emergent equipment of the light to be detected, the optical reference data, the optical test data and the associated data set; The step of adjusting the emitting device according to the type of the emitting device of the light to be detected, the optical reference data, the optical test data and the associated data set specifically includes: When the light emitting device to be measured is LD type, adjusting the optical test data according to the associated data set to determine various parameter differences of cornea position power density, retina facula area and retina power density in the optical test data and the optical reference data after adjustment under different diopters; Adjusting the drive current of the exit device such that the values of the cornea position power density and the retinal power density are below the reference values in the corresponding optical reference data; Adjusting a lens of the exit device to make the retinal spot area higher than a reference value in the corresponding optical reference data to determine correction device optical data; Determining a single use time of the exit device after adjustment according to the dose reference value in the correction device optical data and the optical reference data, so that an actual dose value generated by single use is consistent with the dose reference value or is adjusted in combination with historical clinical data; Or specifically comprises the following steps: When the light to be detected is in the LED type emergent device, the optical test data are adjusted according to the associated data set to determine the differences of various parameters including cornea position power density, retina facula area and retina power density in the optical test data and the optical reference data after adjustment under different diopters; adjusting the LED chip size model, average working current and distance between the collimating lens and the LED chip or self focal length of the emergent device so that the cornea position power density and the retina power density are lower than the reference value corresponding to the optical reference data, and the retina facula area is higher than the reference value corresponding to the optical reference data, so as to determine the optical data of the correction device; and determining the single-use time of the exit device after adjustment according to the optical data of the correction device and the dose reference value in the optical reference data, so that the actual dose value generated by single-use is consistent with the dose reference value or is adjusted by combining with historical clinical data.
2. The method of visually controlling optical power density and safety on a retina according to claim 1, wherein the step of irradiating reference light onto a simulated eye under preset conditions and collecting optical reference data of a cornea region of the simulated eye and a retina region of the simulated eye, the reference light being red sunlight comprises: Collecting illumination data of solar light irradiated on cornea areas and retina areas of a plurality of simulated eyes from sunrise to a target time node in different days under a preset condition and within a preset time period; and screening and fusing all the illumination data to determine the optical reference data, wherein the preset conditions at least comprise fixed places and fixed angles.
3. The method of visually controlling optical power density and safety on a retina according to claim 2, wherein the step of screening and fusing all of the illumination data to determine the optical reference data comprises: acquiring tolerance limit time nodes of naked eyes of an operation observer corresponding to each simulated eye for observing sunrise; Screening the illumination data according to the limit time node to determine target illumination data; and carrying out statistical processing on the target illumination data to determine the optical reference data.
4. The method of visually controlling optical power density and safety on a retina according to claim 1, wherein the step of adjusting the exit device according to the type of the exit device of the light to be measured, the optical reference data, optical test data and the associated data set comprises: a single-sided frosted glass and a collimating lens are sequentially arranged outside an emergent opening of the emergent device, so that emergent light of the emergent device is focused on the single-sided frosted glass to form small light spots, and the small light spots form parallel light through the collimating lens; And adjusting the emergent device according to the optical test data, the optical reference data, the type of the emergent device and the associated data set of the parallel light on the simulated eye.
5. The method of visually controlling optical power density and safety on a retina according to any one of claims 1 to 4, wherein the simulated eye comprises a main body and a single-faced erised glass provided on one side of the main body, the non-transparent side of the single-faced erised glass being the retina of the simulated eye.
6. A visual control system for optical power density and safety on retina is characterized in that, a method for achieving visual control of optical power density and safety on the retina as claimed in any one of claims 1 to 5, the system comprising: A reference data determining module for irradiating reference light on a simulated eye and collecting optical reference data of a cornea region of the simulated eye and a retina region of the simulated eye, wherein the reference light is red sunlight; The test data determining module is used for irradiating light to be tested on the simulated eye and collecting optical test data of a cornea area of the simulated eye and a retina area of the simulated eye; The association data determining module is used for determining association data sets of retina areas of the simulated eyes under different diopters based on an inserting sheet optometry; And the judging and adjusting module is used for adjusting the emergent equipment according to the type of the emergent equipment of the light to be detected, the optical reference data, the optical test data and the associated data set.
7. A computer readable storage medium having stored thereon a computer program, wherein the program when executed by a processor performs the steps of the method of visually controlling optical power density and safety on the retina as claimed in any of claims 1 to 5.
8. An electronic device comprising a memory, a processor, and a computer program stored on the memory and executable on the processor, the processor implementing the method of visually controlling optical power density and security on the retina as claimed in any one of claims 1 to 5 when the program is executed.

Description

Visual control method for optical power density and safety on retina Technical Field The invention relates to the technical field of red light test control, in particular to a method for visually controlling the optical power density and safety on retina. Background Under the circumstance that the global myopia rate continuously rises, particularly the problem of teenagers is increasingly serious, searching for a safe, efficient and easy-to-persist myopia intervention means becomes an urgent need in the medical and scientific research fields. In this context, repeated low intensity red light therapy (REPETITIVE LOW-INTENSITY RED LIGHT, RLRL), also commonly known as a foster light instrument, is rapidly entering the public's field of view as an emerging high-efficiency myopia intervention by virtue of its unique mechanism of action and convenient use, and is of great interest. The device has the core principle that the eye bottom is irradiated by low-intensity red Laser (semiconductor Laser (LD) which is the mainstream in the market at present) with a specific wavelength (such as 650 nm). The use method is simple and convenient, and the abnormal increase of the curvature of the crystalline lens and the excessive extension of the ocular axis can be effectively inhibited only by irradiation for 3 minutes in the morning and evening, so that the purpose of delaying or even reversing the progression of myopia is achieved, and the advantage enables the lens to have huge application potential in the field of myopia prevention and control. The RLRL devices on the market are mainly divided into two types, namely a laser type light-feeding instrument and a non-laser type light-feeding instrument according to the type of the light source. However, in practical application, a series of problems are increasingly highlighted, firstly, the difficulty of comfort and compliance in use. Although the manufacturer claims to use low intensity red light, it was found that the optical power density at the cornea location had reached 2mW/cm2. This intensity results in that most people will obviously feel too strong red light for the first irradiation and will be intolerable. From the medical professional point of view, the situation is directly expressed as poor comfort of the product, so that the treatment compliance of patients is poor, and many patients abandon treatment due to intolerance, so that the popularization and effect of the treatment are seriously affected. Second, it is a safety challenge, and despite the positive efficacy of RLRL therapies in the current state of the art, the long-term safety of red laser intervention has always lacked adequate evidence support, and very few cases of suspected retinal photodamage do occur in clinical applications, and although these cases eventually fully heal, they mask the safety of the therapy. From the above analysis, it is clear that the essential core problem of safety and effectiveness, which currently relates to the field of nursing instruments, is how to accurately characterize the optical power density and spot size on the retina. However, no effective method for detecting and controlling the optical power density and the spot size on the retina is currently provided at home and abroad, and convincing natural reference standards are lacking in the definition of safe doses. Disclosure of Invention Based on the above, the invention aims to provide a visual control method for the optical power density and safety on retina, which aims to solve the problem that a method for measuring and controlling the optical power density and the light spot size of retina in RLRL red light treatment technology is lacking in the prior art. A method of visually controlling optical power density and safety on a retina according to an embodiment of the invention, the method comprising: illuminating reference light on a simulated eye and collecting optical reference data of a cornea region of the simulated eye and a retina region of the simulated eye, wherein the reference light is red sunlight; illuminating light to be detected on a simulated eye, and collecting optical test data of a cornea area of the simulated eye and a retina area of the simulated eye; determining a correlation data set of retina areas of the simulated eye at different diopters based on an insert refraction method; and adjusting the emergent equipment according to the type of the emergent equipment of the light to be detected, the optical reference data, the optical test data and the associated data set. In addition, the method for visually controlling the optical power density and safety on the retina according to the above embodiment of the present invention may further have the following additional technical features: Further, under a preset condition, irradiating reference light onto the simulated eye, and collecting optical reference data of a cornea region of the simulated eye and a retina region of the simulated eye,