Search

CN-121628528-B - Intelligent temperature-sensitive hydrocolloid anti-wear paste and preparation method thereof

CN121628528BCN 121628528 BCN121628528 BCN 121628528BCN-121628528-B

Abstract

The invention discloses an intelligent temperature-sensitive hydrocolloid abrasion-proof patch and a preparation method thereof, belonging to the technical field of medical instruments and sports protective articles, wherein a phase-change material is microencapsulated and mixed with a water-based polyurethane adhesive to form an intelligent phase-change microcapsule layer, then a hydrocolloid mesh skeleton is obtained by molding a hydrocolloid material through a mesh die, then the two materials are compounded by hot pressing, a functional pressure-sensitive adhesive containing plant essential oil is coated on the other side of the skeleton, and finally a protective film and anti-sticking release paper are covered to obtain the hydrocolloid abrasion-proof patch.

Inventors

  • MENG FANWEI

Assignees

  • 马鞍山东毅新材料科技有限公司

Dates

Publication Date
20260512
Application Date
20251225

Claims (10)

  1. 1. The preparation method of the intelligent temperature-sensitive hydrocolloid anti-wear paste is characterized by comprising the following steps of: The method comprises the steps of taking n-octadecane and n-tetradecane as phase change materials and zeolite as core materials, taking carboxymethyl chitosan crosslinked network as wall materials to obtain intelligent phase change microcapsules, uniformly mixing the intelligent phase change microcapsules with a water-based polyurethane adhesive, and coating and drying to obtain an intelligent phase change microcapsule layer; mixing gelatin, pectin and sodium methylcellulose, and injecting into a latticed mold with a continuous intercommunication pore canal structure for molding to obtain a hydrocolloid latticed skeleton; Step three, mixing medical acrylic pressure-sensitive adhesive and plant essential oil to prepare functional pressure-sensitive adhesive; And fourthly, compounding the intelligent phase-change microcapsule layer with one side of the hydrocolloid grid framework in a hot-pressing manner, coating the other side of the framework with a functional pressure-sensitive adhesive, and finally covering a protective film and anti-sticking release paper to obtain the intelligent temperature-sensitive hydrocolloid anti-wear paste.
  2. 2. The method for preparing the intelligent temperature-sensitive hydrocolloid abrasion-proof paste according to claim 1, wherein the hot pressing compounding is hot pressing for 15-45s at the temperature of 70-90 ℃ and the pressure of 0.3-0.6 MPa.
  3. 3. The method for preparing the intelligent temperature-sensitive hydrocolloid wear-resistant patch according to claim 1, wherein the specific preparation steps of the functional pressure-sensitive adhesive are as follows: placing medical acrylic acid ester pressure-sensitive adhesive in a stirring kettle, stirring a base material at room temperature at a rotating speed of 200-400r/min, slowly and dropwise adding plant essential oil, after the essential oil is added, raising the stirring speed to 400-600r/min, continuously stirring for 30-60min, standing colloid for 15-30min after stirring is finished, and eliminating bubbles to obtain a functional pressure-sensitive adhesive layer; The mass ratio of the medical acrylic pressure-sensitive adhesive to the plant essential oil is 100:0.5-2.
  4. 4. The method for preparing the intelligent temperature-sensitive hydrocolloid anti-wear paste according to claim 3, wherein the plant essential oil is obtained by mixing menthol and wintergreen oil according to a mass ratio of 1:1.
  5. 5. The method for preparing the intelligent temperature-sensitive hydrocolloid abrasion-proof paste according to claim 1, wherein the specific preparation steps of the hydrocolloid grid framework are as follows: Putting gelatin into a torque rheometer, melting at 60-70 ℃ and 50-150r/min for 4-6min, adding pectin and sodium methylcellulose, continuously mixing for 15-25min, placing the mixed rubber in a vacuum environment at 50-60 ℃ for standing for 20-40min, injecting into a preheated grid-shaped mold with a continuous intercommunication pore canal structure, transferring to a flat vulcanizing machine, hot-pressing at 80-100 ℃ and 0.2-0.5MPa for 5-15min, cooling the mold to 20-30 ℃, cold-pressing at 2-5MPa for 1-3min, releasing the pressure, and demolding to obtain a hydrocolloid grid framework; The mass ratio of the gelatin to the pectin to the sodium methylcellulose is 80-100:20-40:12-25.
  6. 6. The method for preparing the intelligent temperature-sensitive hydrocolloid wear-resistant patch according to claim 1, wherein the specific preparation steps of the intelligent phase-change microcapsule layer are as follows: Adding adhesive aqueous polyurethane into a stirring kettle, sequentially adding a dispersing agent D045 and intelligent phase-change microcapsules into the kettle at 300-500r/min, continuously stirring for 10-15min, adding a thickening agent HEUR-A and a defoaming agent BYK-022, continuously stirring for 5-8min, standing for 1-2h, pouring the mixture on a release film, coating the release film into a uniform wet film with a scraper, controlling the thickness of the wet film to be 200-500 mu m, drying the wet film at room temperature for 2-4h, and then drying the wet film at 50-60 ℃ for 2-4h to obtain the intelligent phase-change microcapsule layer.
  7. 7. The method for preparing the intelligent temperature-sensitive hydrocolloid wear-resistant patch according to claim 6, wherein the mass ratio of the adhesive aqueous polyurethane to the dispersing agent D045 to the intelligent phase-change microcapsule to the thickening agent HEUR-A to the defoaming agent BYK-022 is 15-25:0.5-1:10-15:0.5-2:0.05-0.10.
  8. 8. The preparation method of the intelligent temperature-sensitive hydrocolloid wear-resistant patch of claim 6, wherein the specific preparation method of the intelligent phase-change microcapsule is as follows: adding carboxymethyl chitosan and deionized water into a reaction kettle, stirring until the carboxymethyl chitosan and the deionized water are dissolved, adding a composite phase-change core material into the kettle, shearing for 5-10min at 5000-7000r/min to form uniform suspension, adding a cross-linking agent sodium tripolyphosphate at 400-600r/min, stirring and reacting for 3-5h at 60-70 ℃, centrifuging and separating after the reaction is finished, washing a filter cake with 50-60 ℃ deionized water, and vacuum drying to obtain an intelligent phase-change microcapsule; the dosage ratio of the carboxymethyl chitosan, the deionized water, the composite phase-change core material and the cross-linking agent sodium tripolyphosphate is 4-8g:350-500mL:12-20g:2-4g.
  9. 9. The method for preparing the intelligent temperature-sensitive hydrocolloid wear-resistant paste according to claim 8, wherein the composite phase-change core material is formed by compounding n-octadecane, n-tetradecane and zeolite according to the mass ratio of 55-65:35-45:95-130.
  10. 10. An intelligent temperature-sensitive hydrocolloid anti-wear patch, characterized by being prepared by the preparation method of any one of claims 1-9.

Description

Intelligent temperature-sensitive hydrocolloid anti-wear paste and preparation method thereof Technical Field The invention belongs to the technical field of medical instruments and sports protective articles, and particularly relates to an intelligent temperature-sensitive hydrocolloid anti-wear patch and a preparation method thereof. Background Hydrocolloid wear-resistant patches are skin protection products widely used in the fields of sports protection and wound care, and mainly reduce skin friction and irritation through the moisture absorption and buffering characteristics of hydrocolloid matrixes such as gelatin, pectin and the like. However, the hydrocolloid abrasion-proof paste in the prior art has significant functional and structural limitations, and is difficult to meet the compound requirements of users on intelligent, comfortable and multifunctional physiotherapy. Firstly, in terms of functions, the conventional products lack intelligent temperature regulation capability, skin is locally easy to overheat due to friction and metabolic heat generation in long-time exercise or high-intensity activity, discomfort and even inflammation are caused, and external cold compress or hot compress is often needed to relieve pain or promote blood circulation in post-exercise recovery period such as sprain or arthritis nursing, but the conventional patch cannot actively provide temperature control support, and a user needs to rely on additional physiotherapy equipment, so that convenience is poor. Secondly, in structural design, conventional hydrocolloid patch is mostly homogeneous film or simple layered structure, and the gas permeability is not enough, causes skin stuffiness, humidity easily, and then causes the problem of allergy or paste infirm, and though some improved generation products try to strengthen the gas permeability through adding hole or net, often sacrifices adhesion strength or function integrated level, and current product is single, and the multiple emphasis is physical protection, and lacks physiotherapy reinforcing characteristic, is difficult to satisfy the user to comfort and long-term physiotherapy's dual demand. In recent years, phase Change Materials (PCM) and microcapsule technologies have been explored in the fields of textile, medical treatment and the like and used for temperature management, but the application of combining the PCM and a hydrocolloid anti-wear paste is still less, the prior attempts are limited to simple mixing, the method is difficult to ensure the uniform distribution of the phase change materials in a matrix, the microcapsule is easy to be damaged and the phase change materials are easy to leak due to the volume change of the phase change materials in the phase change process, a series of linkage adverse reactions such as failure of temperature control function, skin irritation, patch structure damage, product reliability reduction and the like are caused, so that the intelligent temperature sensing function cannot be realized, and new safety and use problems are more likely to be generated. Disclosure of Invention The invention aims to provide an intelligent temperature-sensitive hydrocolloid anti-wear patch and a preparation method thereof, and the active buffering of friction heat and the dynamic management of skin microenvironment damp and heat are realized through the synergistic effect of heat storage and release of phase-change microcapsules, rapid moisture conduction of hydrocolloid grids and reliable adhesion of functional pressure-sensitive adhesives, so that the effects of firm adhesion and comfortable tearing are achieved, and the problems of stuffy, no temperature control, easy falling and uncomfortable tearing of the traditional anti-wear patch are effectively solved. The aim of the invention can be achieved by the following technical scheme: a preparation method of an intelligent temperature-sensitive hydrocolloid anti-wear paste comprises the following steps: the method comprises the steps of taking n-octadecane and n-tetradecane as phase change materials and zeolite as core materials, taking carboxymethyl chitosan crosslinked network as wall materials to obtain intelligent phase change microcapsules, uniformly mixing the intelligent phase change microcapsules with a water-based polyurethane adhesive, and coating and drying to obtain the intelligent phase change microcapsule layer. And step two, mixing gelatin, pectin and sodium methylcellulose, and injecting into a latticed mold with a continuous intercommunication pore canal structure for molding to obtain the hydrocolloid latticed skeleton. And step three, mixing the medical acrylic pressure-sensitive adhesive and the plant essential oil to prepare the functional pressure-sensitive adhesive. And fourthly, compounding the intelligent phase-change microcapsule layer with one side of the hydrocolloid grid framework in a hot-pressing manner, coating the other side of the framework with a fun