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CN-121667386-B - Composition for improving skin moisture condition and resisting oxidation, and preparation method and application thereof

CN121667386BCN 121667386 BCN121667386 BCN 121667386BCN-121667386-B

Abstract

The invention provides a composition for improving skin moisture condition and resisting oxidation, a preparation method and application thereof, and relates to the technical field of foods. The composition comprises, by weight, 35-75 parts of tremella polysaccharide, 40-80 parts of sodium hyaluronate, 20-40 parts of collagen tripeptide, 20-40 parts of Opuntia ficus-indica extract, 5-15 parts of black fruit mountain ash powder, 5-15 parts of Meinaria oil, 10-30 parts of medlar puree and 1-3 parts of vitamin C, wherein the Opuntia ficus-indica extract is obtained by juicing Opuntia ficus-indica, treating with lactobacillus acidophilus, lactobacillus and cellulase, and extracting with subcritical water, and has a high yield. The composition of the invention brings remarkable water retention and moisture retention, and increases skin elasticity and oxidation resistance.

Inventors

  • BAI JINPING
  • WANG SHUWEN
  • WANG YUYING
  • WANG CHAO
  • LIANG XIAOHUA

Assignees

  • 德州蓝力生物技术有限公司
  • 广东西乐健康科技股份有限公司

Dates

Publication Date
20260508
Application Date
20260210

Claims (10)

  1. 1. A composition for improving skin moisture and resisting oxidation is characterized by comprising, by weight, 35-75 parts of tremella polysaccharide, 40-80 parts of sodium hyaluronate, 20-40 parts of collagen tripeptide, 20-40 parts of Opuntia ficus-indica extract, 5-15 parts of black chokeberry powder, 5-15 parts of merry go round robinia oil, 10-30 parts of medlar puree and 1-3 parts of vitamin C; the preparation method of the Opuntia ficus-indica extract comprises the following steps: (1) Mixing Opuntia ficus-indica with water, squeezing, and filtering to obtain filtrate A and residue A; (2) Mixing the filter residue A with water, treating with Lactobacillus acidophilus, lactobacillus and cellulase, and filtering to obtain filtrate B and filter residue B; (3) The filter residue B adopts a subcritical water extraction system, and water is used as a solvent for carrying out staged extraction: The first stage comprises extracting at 110-130deg.C under 2.0-4.0MPa, and filtering to obtain filtrate C and residue C; The second stage comprises extracting at 140-160deg.C under 4.5-5.5MPa, and filtering to obtain filtrate D and residue D; (4) And combining the filtrate A, the filtrate B, the filtrate C and the filtrate D to obtain the Opuntia ficus-indica extract.
  2. 2. The composition according to claim 1, which is characterized by comprising, by weight, 40-60 parts of tremella polysaccharide, 50-70 parts of sodium hyaluronate, 25-35 parts of collagen tripeptide, 25-35 parts of Opuntia ficus-indica extract, 8-12 parts of Sorbus nigra powder, 8-12 parts of Meinaria lubilis oil, 15-25 parts of Lycium barbarum puree and 1.5-2.5 parts of vitamin C.
  3. 3. The composition according to claim 2, which comprises, by weight, 50 parts of tremella polysaccharide, 60 parts of sodium hyaluronate, 30 parts of collagen tripeptide, 30 parts of opuntia ficus-indica extract, 10 parts of black chokeberry powder, 10 parts of merry-go-round oil, 20 parts of medlar puree and 2 parts of vitamin C.
  4. 4. A composition according to any one of claims 1 to 3, wherein the juice is extracted in step (1) and the solid to liquid ratio of opuntia ficus-indica to water is 1g:20-30mL, and the juice is extracted in step (1) and is subjected to a 300-500W juice extraction treatment for 3-10min.
  5. 5. A composition according to any one of claims 1 to 3, wherein in step (2) the filter residue a is mixed with water in a solids to liquid ratio of 1g:10-20mL, wherein the mass of solids is calculated on the basis of the opuntia ficus-indica of step (1); In the step (2), the mass ratio of the lactobacillus acidophilus to the lactobacillus is 1:2-4.
  6. 6. A composition according to any one of claims 1 to 3, wherein in step (2) the total amount of lactobacillus acidophilus and lactobacillus is 5% to 10% of the mass of opuntia ficus; in the step (2), the dosage of the cellulase is 50-150U/g, and in the step (2), the treatment condition is that the treatment is carried out for 12-48 hours at 34-40 ℃.
  7. 7. A composition according to any one of claims 1 to 3, wherein in step (3) the flow rate of water in the staged extraction is 2-4mL/min.
  8. 8. A composition according to any one of claims 1 to 3, characterized in that in step (3) the conditions of the first stage are in particular 110-130 ℃, pressure 2.0-4.0MPa extraction for 10-20min; In the step (3), the conditions of the second stage are specifically 140-160 ℃ and 4.5-5.5MPa for extraction for 5-10min.
  9. 9. The method for preparing the composition according to any one of claims 1 to 8, comprising the steps of uniformly mixing tremella polysaccharide, sodium hyaluronate, collagen tripeptide, opuntia ficus-indica extract, sorbus nigra powder, meinaria oil, fructus Lycii puree and vitamin C, and freeze-drying to obtain the composition.
  10. 10. Use of a composition according to any one of claims 1 to 8 for the preparation of a food product having improved skin moisture conditions and antioxidant properties.

Description

Composition for improving skin moisture condition and resisting oxidation, and preparation method and application thereof Technical Field The invention belongs to the technical field of foods, and particularly relates to a composition for improving skin moisture condition and resisting oxidization, and a preparation method and application thereof. Background The food market with "oral cosmetic" function is rapidly evolving as consumers' awareness of skin health changes from exogenous care to endogenous conditioning. The healthy appearance of skin, particularly the degree of moisture, elasticity and gloss, is fundamentally dependent on its ability to retain moisture and resist oxidative damage. The integrity of the stratum corneum, the content of natural moisturizing factors and the state of the dermis matrix (such as hyaluronic acid and collagen) jointly determine the water storage capacity of the skin, and excessive active oxygen free radicals generated by factors such as environmental ultraviolet rays, pollution and the like attack skin cells to accelerate hyaluronic acid degradation, collagen crosslinking and lipid peroxidation, so that the skin is dry, loses elasticity and aged. At present, sodium hyaluronate is a hot component studied in the field, and oral hyaluronic acid can be absorbed and distributed to skin to increase the hyaluronic acid content of dermis and epidermis so as to improve skin moisture, and in addition, some natural plant extracts such as tremella polysaccharide, aloe extract, cactus fruit extract and the like are rich in polysaccharide, polyphenol and the like, so that the components have the characteristics of promoting hyaluronic acid synthesis, resisting inflammation, moisturizing and the like in vitro or animal models. Therefore, in the conventional food, sodium hyaluronate and a plant polysaccharide component, and a plant extract component are often mixed and used. For example, in chinese patent CN114287631a, it is pointed out that small molecular sodium hyaluronate with average molecular weight of 80KDa-800KDa has the effect of significantly increasing skin water content, and collagen peptide and small molecular sodium hyaluronate are both small molecules, so that they are easy to be absorbed by human body. The composition is prepared by mixing collagen peptide hydrolysate, small molecular sodium hyaluronate hydrolysate, elastin, nidus Collocaliae powder, mangosteen powder, salmon nasal cartilage powder, echinacea purpurea pollen, astaxanthin, tremella polysaccharide, vitamin C and concentrated juice, and has effects in improving skin aging, recovering skin elasticity, increasing skin moisture content, reducing skin moisture evaporation, increasing pre-collagen secretion, promoting collagen biosynthesis, and relieving skin redness and sensitive symptoms. Chinese patent CN119769734A describes a composition for improving skin water retention and water locking capability and a preparation method thereof, and the preparation method comprises the following steps of preparing starch salmon nasal cartilage composite nano powder; preparing flavored moisturizing tremella polysaccharide fermentation liquor, and compounding light enzymolysis liquor of salmon nasal cartilage with tremella polysaccharide fermentation liquor. Uniformly mixing the flavored moisturizing tremella polysaccharide fermentation liquor, the salmon nasal cartilage powder light enzymatic hydrolysate, maltodextrin, the cherokee rose flower extract and the low methoxy pectin, and then performing vacuum freeze drying to obtain the composition capable of improving the skin water retention and water locking capacity. However, the absorption rate of the sodium hyaluronate or polysaccharide (extract) component with large molecular weight is low when the composition is orally taken, so that the water retention or oxidation resistance of the composition is affected. Furthermore, the existing moisturizing schemes are often separated from antioxidant schemes, and in fact, oxidative stress is a core driving factor which leads to degradation of skin moisturizing components (such as hyaluronic acid and collagen), peroxidation of barrier lipids and exacerbation of inflammatory reaction, and the moisturizing effect is like "tower construction on sand" and is difficult to last without fundamentally relieving oxidative pressure. The existing composition has less stimulation on simultaneous synthesis of endogenous moisturizing factors and skin hyaluronic acid, and the lack of systemic action limits the overall efficacy of improving the skin hydration state and resisting environmental attack. In view of this, there is a need to develop a composition that can simultaneously address the two core mechanisms of "moisturization" and "antioxidation" so that the component design is more scientific, that exhibits a targeted synergistic mechanism, and that can effectively cope with the damage of oxidative stress to the skin moisturization syste