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CN-121970756-A - Suspending agent containing trifluoropyridinamine and fosthiazate and preparation method thereof

CN121970756ACN 121970756 ACN121970756 ACN 121970756ACN-121970756-A

Abstract

The invention discloses a suspension containing trifluoropyridine amine and fosthiazate and a preparation method thereof, and belongs to the technical field of pesticides. The invention introduces an autonomously synthesized specific suspension system, can form excellent network structure and interfacial activity, is more stable, and has synergistic effect with a specific ratio of composite dispersing agent (fatty alcohol polyoxyethylene ether phosphate and maleic anhydride-polystyrene copolymer), and the suspension rate and the dispersibility are excellent, so that two different raw medicines are more stable in the storage process. In addition, the trifluopicoline amine and the fosthiazate are compounded and prepared into a suspending agent, the active ingredients with two different action mechanisms can be released and distributed at the infection sites of rhizosphere soil or crop diseases more synchronously and permanently after application, the disease control effect generated by component compounding is obviously superior to that of each single agent and simple physical mixing of the single agent and the single agent, the control spectrum is effectively widened, the preparation process is simple, the industrial production is easy, and the whole processing process is stable.

Inventors

  • FENG BAOYI
  • LIU TIANKAI
  • ZHAO ZHONGKUI
  • AN JUAN
  • ZHENG HUO
  • ZHANG KEXIN
  • LI DAZHONG

Assignees

  • 佛山市盈辉作物科学有限公司

Dates

Publication Date
20260505
Application Date
20260116

Claims (10)

  1. 1. A suspension agent containing trifluoropyridine amine and fosthiazate is characterized by comprising, by mass, 1% -20% of trifluoropyridine amine, 0.5% -20% of fosthiazate, 5% -10% of a composite dispersing agent, 8% -15% of a suspension system, 1% -3% of lecithin, 1% -6% of a wetting agent, 0.1% -3% of a thickening agent, 2% -7% of an antifreezing agent, 0.1% -1% of a defoaming agent, 0.1% -0.5% of a preservative and the balance of deionized water; The preparation method of the suspension system comprises the steps of adding epoxidized soybean oil, polyethylene glycol, methyl methacrylate and fatty alcohol-polyoxyethylene ether into a reaction kettle, heating to 45-65 ℃, stirring at a rotating speed of 100-200 r/min for 20-30 min, adding potassium dodecyl phosphate and potassium persulfate, heating to 75-85 ℃, continuing stirring for 1-3 h, and cooling to obtain the suspension system.
  2. 2. The suspending agent according to claim 1, wherein the epoxy soybean oil, polyethylene glycol, methyl methacrylate, fatty alcohol polyoxyethylene ether, potassium dodecyl phosphate and potassium persulfate are in a weight ratio of (10-20): 2-5): 1-2): 0.1-0.5.
  3. 3. The suspending agent according to claim 1, wherein the composite dispersing agent is obtained by mixing (1-2) fatty alcohol polyoxyethylene ether phosphate and maleic anhydride-polystyrene copolymer in parts by weight.
  4. 4. A suspending agent according to claim 3, wherein the mass percentage of maleic anhydride in the maleic anhydride-polystyrene copolymer is 35% -40%.
  5. 5. The suspension of claim 1, wherein the wetting agent is at least one of alkylphenol ethoxylates, fatty alcohol ethoxylates, alkyl naphthalene sulfonates, alkyl sulfates, dioctyl sodium sulfosuccinate.
  6. 6. The suspending agent according to claim 1, wherein the thickener is obtained by mixing sodium carboxymethyl cellulose and magnesium aluminum silicate in a mass ratio of (1-2): (1-5).
  7. 7. The suspending agent according to claim 1, wherein the antifreeze is at least one of ethylene glycol, propylene glycol, urea, and glycerin.
  8. 8. A suspension as claimed in claim 1, wherein, the defoamer is polydimethylsiloxane.
  9. 9. The suspension of claim 1, wherein the preservative is at least one of isothiazolinone, sodium benzoate, and pinocembrane.
  10. 10. A method for preparing a suspension containing trifluoropyridine amine and fosthiazate, which is characterized in that the method is used for preparing the suspension containing trifluoropyridine amine and fosthiazate according to any one of claims 1-9, and comprises the following steps: S1, uniformly mixing a composite dispersing agent, lecithin, a wetting agent, a defoaming agent and deionized water, and stirring at a rotating speed of 100-300 r/min for 20-30 min to obtain a dispersion liquid A; s2, adding the trifluoropyridine amine and the fosthiazate into the dispersion liquid A, uniformly mixing, and grinding until the particle size D90 of the material is less than or equal to 5 mu m to obtain a dispersion liquid B; S3, adding the suspension system into the dispersion liquid B, stirring at the rotating speed of 50-100 r/min at 45-60 ℃ for 1-3 hours, cooling to 30-35 ℃, adding a thickening agent, an antifreezing agent and a preservative, continuing stirring for 10-20 minutes, supplementing deionized water to the specified mass, and removing a grinding medium to obtain the suspension agent.

Description

Suspending agent containing trifluoropyridinamine and fosthiazate and preparation method thereof Technical Field The invention relates to the technical field of pesticides, in particular to a suspension containing trifluoropyridine amine and fosthiazate and a preparation method thereof. Background The pesticide suspending agent is a high-dispersion stable suspension system formed by dispersing insoluble or slightly water-soluble solid raw pesticide in water through wet grinding by aid of an auxiliary agent system. Because the pesticide uses water as a matrix, the pesticide has the advantages of environmental protection, safe production and use, difficult generation of phytotoxicity, convenient barrel mixing and the like, and has become an important development direction of modern pesticide preparations. The trifluoropyridinamine is a novel pyridinamide bactericide, is mainly used for preventing and treating oomycete diseases, such as downy mildew, late blight and the like, and has the characteristics of good systemic conductivity, unique action mechanism and safety to environment and non-target organisms. In addition, the trifluoropyridine amine has dual activities of sterilization and nematicidal, and has the action mechanism that the tricarboxylic acid cycle on the respiratory electron transfer chain complex II can be interfered, the function of mitochondria can be inhibited, the energy generation of the tricarboxylic acid can be prevented, the growth of pathogenic bacteria can be inhibited, and the death of the tricarboxylic acid can be finally caused. The nematode larvae can also be paralyzed by interfering with respiration, thereby leading to energy exhaustion in cells and inhibiting egg hatching. The fosthiazate is an organophosphorus nematicide, has the functions of contact killing and internal sucking, can effectively prevent and control various soil nematodes such as root knot nematodes and cyst nematodes, and has the effect of controlling soil pests at a certain time. In actual agricultural production, crops often face composite infection of soil-borne diseases (such as root and stem diseases caused by phytophthora) and nematode at the same time, resulting in serious yield reduction. The bactericide and the nematicide are scientifically compounded to realize one-time application and synergistic control, and the method has important significance in simplifying farm work operation, reducing medication cost and improving control effect. In the prior art, the technical problem to be solved still exists in processing pesticide raw materials with different chemical structures and physicochemical properties into a stable composite suspending agent. Because of the difference of solubility, polarity, density and other physical properties of the trifluoropyridine amine and the fosthiazate, particle aggregation, growth (Oryza curing) or layered precipitation are easy to cause in the storage process, so that the physical stability and the biological activity of the preparation are affected. Secondly, the conventional suspending agent formula and the conventional preparation process are difficult to simultaneously consider the fineness, the suspension rate and the long-term storage stability of the two raw materials, and the problems of creaming, bottoming, enlargement and the like of the preparation are easy to cause, so that inconvenience is brought to production, transportation and use. At present, the related technologies of the single-dose suspension of the trifluoropyridine amine or the fosthiazate are less, and the development of the trifluoropyridine amine and fosthiazate compound suspension which has excellent physical and chemical stability, is convenient to use and can cooperatively control soil-borne diseases and nematode diseases has important significance for meeting the requirements of modern green agriculture. Disclosure of Invention Based on the above, in order to solve one of the technical problems, the invention provides a suspension containing trifluoropyridine amine and fosthiazate and a preparation method thereof, and the specific technical scheme is as follows: The suspending agent comprises, by mass, 1% -20% of trifluoropyridine amine, 0.5% -20% of fosthiazate, 5% -10% of a composite dispersing agent, 8% -15% of a suspending system, 1% -3% of lecithin, 1% -6% of a wetting agent, 0.1% -3% of a thickening agent, 2% -7% of an antifreezing agent, 0.1% -1% of a defoaming agent, 0.1% -0.5% of a preservative and the balance of deionized water; The preparation method of the suspension system comprises the steps of adding epoxidized soybean oil, polyethylene glycol, methyl methacrylate and fatty alcohol-polyoxyethylene ether into a reaction kettle, heating to 45-65 ℃, stirring at a rotating speed of 100-200 r/min for 20-30 min, adding potassium dodecyl phosphate and potassium persulfate, heating to 75-85 ℃, continuing stirring for 1-3 h, and cooling to obtain the suspension system. Preferably, t