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CN-121971087-A - Intermittent body fluid parameter detection method, device and related system

CN121971087ACN 121971087 ACN121971087 ACN 121971087ACN-121971087-A

Abstract

The application provides a detection method, a device and a related system for intermittent body fluid parameters, which belong to the technical field of human body blood oxygen detection, and are characterized in that an intermittent body fluid monitoring instruction is obtained, a monitoring mode is determined according to the intermittent body fluid monitoring instruction, then a first control instruction for a reagent pack is determined according to a reagent calibration mode, a peristaltic pump and a fluid selector are controlled according to the first control instruction to obtain a first compensation parameter of a test card, an automatic acquisition device is controlled to acquire target body fluid of a target user, the target body fluid is conveyed to a first pipeline through a sampling interface, a second control instruction for the reagent pack is determined according to the body fluid detection mode, the peristaltic pump and the fluid selector are controlled to absorb the target body fluid according to the second control instruction to generate a first body fluid detection parameter, and the target body fluid detection parameter of the target user is obtained by calculation according to the first compensation parameter and the first body fluid detection parameter. The accuracy of body fluid parameter detection can be improved.

Inventors

  • YE MAOLIN

Assignees

  • 深圳市美连医疗电子股份有限公司

Dates

Publication Date
20260505
Application Date
20260327

Claims (10)

  1. 1. A detection method of intermittent body fluid parameters is characterized by being applied to a main controller in an intermittent body fluid parameter monitoring system, the intermittent body fluid parameter monitoring system further comprises a test card detachably connected with the main controller, a reagent pack connected with the main controller and an automatic sampling device in communication connection with the main controller, wherein the reagent pack comprises a fluid selector, a peristaltic pump and a plurality of liquid containers connected with the fluid selector, and the fluid selector is communicated with a sampling interface, and the method comprises the following steps: acquiring an intermittent body fluid monitoring instruction, and determining a monitoring mode according to the intermittent body fluid monitoring instruction, wherein the monitoring mode comprises a reagent calibration mode and a body fluid detection mode; Determining a first control instruction for the reagent pack according to the reagent calibration mode, and sending the first control instruction to the reagent pack; Controlling the peristaltic pump and the fluid selector according to the first control instruction so as to enable various liquid media in the liquid containers to flow through a first position of the test card through a first pipeline to obtain a first detection signal; Generating a first compensation parameter of the test card according to the first detection signal; controlling the automatic acquisition device to acquire target body fluid of a target user and conveying the target body fluid to the first pipeline through the sampling interface; Determining a second control instruction for the reagent pack according to the body fluid detection mode, and sending the second control instruction to the reagent pack; controlling the peristaltic pump and the fluid selector to absorb the target body fluid according to the second control instruction, obtaining a second detection signal of the test card when the target body fluid flows through the first position, and generating a first body fluid detection parameter of the test card according to the second detection signal; and calculating according to the first compensation parameter and the first body fluid detection parameter to obtain the target body fluid detection parameter of the target user.
  2. 2. The method of claim 1, wherein the plurality of fluid containers includes a calibration fluid container provided with a calibration fluid medium and a quality control fluid container provided with a quality control fluid medium, wherein the master controller further includes a fluid level sensor, and wherein the controlling the peristaltic pump and the fluid selector according to the first control command to flow a plurality of fluid media in the plurality of fluid containers through a first position of the test card via a first line to obtain a first detection signal includes: determining a first rotational command for operation of the peristaltic pump according to the first control command, and determining a first selection command for operation of the fluid selector according to the first control command; determining a switch selection state of the fluid selector according to the first selection instruction, wherein the switch selection state comprises a calibration switch state and a quality control switch state; the calibration switch is controlled to be in an on state, and the peristaltic pump is controlled according to the first rotating instruction so that the calibration liquid medium in the calibration liquid container passes through the second position of the liquid level sensor in the first pipeline; When the calibration liquid medium flows through the second position, controlling the peristaltic pump to stop executing the first rotating instruction, and acquiring a first calibration signal of the test card; Controlling the state of the quality control switch to be on, and controlling the peristaltic pump according to the first rotating instruction so as to enable the quality control liquid medium in the quality control liquid container to pass through the second position; when the quality control liquid medium flows through the second position, controlling the peristaltic pump to stop executing the first rotating instruction, and acquiring a first quality control signal of the test card; and processing the first calibration signal and the first quality control signal to obtain the first detection signal.
  3. 3. The method of claim 2, wherein the plurality of liquid containers further comprises a rinse liquid container and a waste liquid collection container, the rinse liquid container being provided with a rinse liquid medium, the method further comprising, prior to the controlling the quality control switch state to be open and controlling the peristaltic pump in accordance with the first rotational command to cause the quality control liquid medium in the quality control liquid container to pass through the second position: Controlling the switch selection state of the fluid selector to be a flushing switch state, and controlling the peristaltic pump to execute the first rotating instruction so that the flushing fluid medium flows through the first pipeline and sequentially flows through the first position and the second position; After the flushing liquid flows through the second position, the peristaltic pump is controlled to pump the calibration liquid medium and the flushing liquid medium to the waste liquid collecting container.
  4. 4. A method according to any of claims 1-3, wherein said generating a first compensation parameter of said test card from said first detection signal comprises: determining a second calibration signal and a second quality control signal for the test card in the first detection signal; Extracting characteristic parameters of the second calibration signal to obtain a first detection parameter of the test card aiming at the action of the calibration liquid medium; extracting characteristic parameters of the second quality control signal to obtain a second detection parameter of the test card aiming at the quality control medium; checking the second detection parameters based on preset quality control checking conditions to obtain checking results; If the verification result meets the quality control verification condition, performing compensation calculation on the test card according to the first detection parameter to obtain the first compensation parameter of the test card; and if the verification result does not meet the quality control verification condition, determining the first compensation parameter according to a preset compensation algorithm for the first detection parameter and the second detection parameter, and outputting quality control information.
  5. 5. The method of claim 4, wherein the extracting the characteristic parameter of the second quality control signal to obtain the second detection parameter of the test card acting on the quality control medium comprises: acquiring a first accuracy parameter of the test card aiming at the quality control medium; Analyzing the signal characteristic parameters of the second quality control signal to obtain a third detection parameter and a second accuracy parameter corresponding to the third detection parameter; determining a difference value between the first accuracy parameter and the second accuracy parameter to obtain an accuracy deviation; determining the accuracy weight of the test card to the quality control medium according to the accuracy deviation; and carrying out weighted calculation according to the accuracy weight and the third detection parameter to obtain the second detection parameter.
  6. 6. A method according to any one of claims 1-3, wherein said controlling said peristaltic pump and said fluid selector to aspirate said target bodily fluid in accordance with said second control command comprises: Determining a body fluid selection state corresponding to the target body fluid by the fluid selector according to the second control instruction; controlling the body fluid selection state of the fluid selector to be an opening state, and controlling the peristaltic pump to pump the target body fluid according to the second rotation instruction so that the target body fluid flows through the test card; After said controlling said peristaltic pump to pump said target bodily fluid according to said second rotational command, said method further comprises: and controlling the fluid selector to select a flushing switch, and controlling the peristaltic pump to execute the second rotation instruction so as to enable flushing fluid in the liquid containers to flow to a waste liquid bag through the first pipeline.
  7. 7. A method according to any one of claims 1-3, wherein said calculating based on said first compensation parameter and said first body fluid detection parameter to obtain a target body fluid detection parameter of said target user comprises: calculating according to the first compensation parameter and the body fluid detection parameter to obtain a second body fluid detection parameter; Determining a difference value between the second body fluid detection parameter and the first body fluid detection parameter to obtain a body fluid detection difference value; Comparing the body fluid detection difference value with a preset body fluid deviation threshold value to obtain a comparison result; If the comparison result is that the body fluid detection difference value is smaller than or equal to the body fluid deviation threshold value, determining the second body fluid detection parameter as the target body fluid detection parameter; and if the comparison result is that the body fluid detection difference value is larger than the body fluid deviation threshold value, determining the target body fluid detection parameter based on a preset parameter correction algorithm and the first body fluid detection parameter.
  8. 8. The intermittent body fluid parameter monitoring system is characterized by comprising a test card detachably connected with the main controller, a reagent pack connected with the main controller, and an automatic sampling device in communication connection with the main controller, wherein the reagent pack comprises a fluid selector, a peristaltic pump and a plurality of liquid containers connected with the fluid selector, the fluid selector is communicated with a sampling interface, and the device comprises: An acquisition unit for acquiring intermittent body fluid monitoring instructions; The device comprises a determining unit, a determining unit and a detecting unit, wherein the monitoring unit is used for determining a monitoring mode according to the intermittent body fluid monitoring instruction, the monitoring mode comprises a reagent calibration mode and a body fluid detection mode, determining a first control instruction aiming at the reagent pack according to the reagent calibration mode, and sending the first control instruction to the reagent pack; The control unit is used for controlling the peristaltic pump and the fluid selector according to the first control instruction so as to enable various liquid media in the liquid containers to flow through a first position of the test card through a first pipeline to obtain a first detection signal, generating a first compensation parameter of the test card according to the first detection signal, controlling the automatic acquisition device to acquire target body fluid of a target user, and conveying the target body fluid to the first pipeline through the sampling interface; And the output unit is used for calculating according to the first compensation parameter and the first body fluid detection parameter to obtain the target body fluid detection parameter of the target user.
  9. 9. An electronic device comprising a processor, a memory, a communication interface, and one or more programs stored in the memory and configured to be executed by the processor, the programs comprising instructions for performing the steps in the method of any of claims 1-7.
  10. 10. A system for detecting an intermittent bodily fluid parameter, wherein the system for detecting an intermittent bodily fluid parameter performs the method of any of claims 1-7.

Description

Intermittent body fluid parameter detection method, device and related system Technical Field The application relates to the technical field of human body blood oxygen detection, in particular to a method, a device and a related system for detecting intermittent body fluid parameters. Background At present, blood gas analysis has important clinical value in critical patient management, and monitoring of blood gas parameters can provide key basis for evaluation of oxygen and ventilation and acid-base balance states. Along with the wide application of technologies such as in-vitro pulmonary membrane oxygenation, the requirements for real-time and accurate detection of blood gas parameters are continuously improved. The existing blood gas detection mode mostly relies on manual blood sampling and off-line analysis, and has the defects of large blood sampling amount, long detection period, incapability of real-time monitoring and the like. The partial continuous blood gas monitoring system is only suitable for an extracorporeal circulation passage, is limited in applicable scene, and has limited detection parameters and lower precision. In addition, in the process of multiple monitoring, the detection device lacks standardization, is easy to cause the problems of distortion of monitoring results, inaccurate detection of body fluid parameters and the like, and is difficult to meet the reliable monitoring requirements of scenes such as clinic, animal experiments, isolated organ culture and the like. Therefore, how to improve the accuracy of intermittent body fluid parameter detection is needed to be solved. Disclosure of Invention The application aims to provide a method, a device and a related system for detecting intermittent body fluid parameters, which solve the problem of poor accuracy of detecting blood gas parameters in the existing blood gas monitoring device. In order to achieve the object of the application, the application provides the following solutions: In a first aspect, the application provides a detection method of intermittent body fluid parameters, which is applied to a main controller in an intermittent body fluid parameter monitoring system, the intermittent body fluid parameter monitoring system further comprises a test card detachably connected with the main controller, a reagent pack connected with the main controller and an automatic sampling device in communication connection with the main controller, wherein the reagent pack comprises a fluid selector, a peristaltic pump and a plurality of liquid containers connected with the fluid selector, and the fluid selector is communicated with a sampling interface, and the method comprises the following steps: acquiring an intermittent body fluid monitoring instruction, and determining a monitoring mode according to the intermittent body fluid monitoring instruction, wherein the monitoring mode comprises a reagent calibration mode and a body fluid detection mode; Determining a first control instruction for the reagent pack according to the reagent calibration mode, and sending the first control instruction to the reagent pack; Controlling the peristaltic pump and the fluid selector according to the first control instruction so as to enable various liquid media in the liquid containers to flow through a first position of the test card through a first pipeline to obtain a first detection signal; Generating a first compensation parameter of the test card according to the first detection signal; controlling the automatic acquisition device to acquire target body fluid of a target user and conveying the target body fluid to the first pipeline through the sampling interface; Determining a second control instruction for the reagent pack according to the body fluid detection mode, and sending the second control instruction to the reagent pack; controlling the peristaltic pump and the fluid selector to absorb the target body fluid according to the second control instruction, obtaining a second detection signal of the test card when the target body fluid flows through the first position, and generating a first body fluid detection parameter of the test card according to the second detection signal; and calculating according to the first compensation parameter and the first body fluid detection parameter to obtain the target body fluid detection parameter of the target user. In a second aspect, the application provides a detection device of intermittent body fluid parameters, which is applied to a main controller in an intermittent body fluid parameter monitoring system, the intermittent body fluid parameter monitoring system further comprises a test card detachably connected with the main controller, a reagent pack connected with the main controller, and an automatic sampling device in communication connection with the main controller, wherein the reagent pack comprises a fluid selector, a peristaltic pump and a plurality of liquid containers connected wit