CN-121971134-A - Embolic coil implantation system

Abstract

The present invention provides an embolic coil implantation system comprising a microcoil having a portion comprising one or more sets of loops. The loops of each of the one or more sets continuously intersect each other in a cycle, collectively forming a three-dimensional shape. A shape setting apparatus includes a three-dimensional (3D) body having a curved surface and a plurality of winding members extending from the curved surface of the 3D body and arranged in a plurality of groups. The winding members of each of the plurality of groups are configured to allow the microcoil to be wound to form loops, and adjacent groups of winding members share the winding members to allow loops formed by adjacent groups to cross each other. A method of manufacturing an embolic device is also provided.

Inventors

• ROSS SOLTANIAN

Assignees

• 北京深瑞达医疗科技有限公司

Dates

Publication Date

20260505

Application Date

20221229

Priority Date

20221201

Claims (20)

1. 1. A method of making an embolic device, comprising: obtaining a microcoil and a shape setting device comprising a 3D body having a curved surface, and a plurality of winding members extending from the curved surface and arranged in a plurality of groups; Winding the microcoil around the 3D body in a first cycle on the winding members of the plurality of groups to form a first group of loops continuously crossing each other, and Heating the microcoil on the shape-setting device to obtain an embolic device comprising the first set of loops having a three-dimensional shape configuration.
2. 2. The method of claim 1, wherein in the first cyclical winding, the microcoil winds a single loop on each of the plurality of sets of winding members.
3. 3. The method of claim 2, wherein the single ring comprises a complete ring.
4. 4. The method of claim 2, wherein the first set of rings comprises two complete rings.
5. 5. The method of claim 2, wherein the single ring comprises a ring comprised of two partial rings.
6. 6. The method of claim 1, further comprising: Winding the microcoil around the 3D body in a second cycle on the plurality of groups of winding members to form a second group of loops continuously intersecting each other, wherein the second group of loops covers and is substantially concentric with the first group of loops, and Wherein said heating comprises heating said microcoil on said shape setting device to obtain said embolic device comprising said first set of rings and said second set of rings.
7. 7. The method of claim 6, wherein in the second cyclical winding, the microcoil winds a single loop on each of the plurality of sets of winding members.
8. 8. The method of claim 6, wherein the single loop in the second endless winding comprises a complete loop.
9. 9. The method of claim 6, wherein the single loop in the second endless winding comprises a loop comprised of two partial loops.
10. 10. The method of claim 6, wherein each of the first set of rings and the second set of rings comprises at least two complete rings.
11. 11. The method of claim 5, further comprising repeating the winding step in one to fourteen cycles.
12. 12. An embolic device comprising a microcoil having a primary configuration, wherein: The microcoil includes a first portion having a secondary configuration, the first portion in the secondary configuration including one or more sets of loops, the loops of each of the one or more sets intersecting one another continuously in a cycle, collectively forming a three-dimensional shape.
13. 13. The embolic device of claim 12, wherein the loops of each of the one or more sets intersect at a middle portion of the loops of each of the one or more sets along the loop.
14. 14. The embolic device of claim 13, wherein the one or more sets of rings comprise a first set of rings and a second set of rings overlaying the first set of rings, wherein the first set of rings and the second set of rings are substantially concentric.
15. 15. The embolic device of claim 14, wherein the diameter of the second set of rings is greater than the diameter of the first set of rings.
16. 16. The embolic device of claim 12, wherein said one or more sets of rings comprise two to fourteen sets, wherein said two to fourteen sets of rings are substantially concentric.
17. 17. The embolic device of claim 16, wherein said two to fourteen sets of loops extend a length of said microcoil, said length ranging from 20mm to 400mm.
18. 18. The embolic device of claim 12, wherein at least one of said one or more sets of rings comprises a first ring, a second ring, and one or more intermediate rings between said first ring and said second ring, wherein said first ring, said second ring, and said one or more intermediate rings continuously intersect each other in a cycle, collectively forming a generally spherical or ellipsoidal shape.
19. 19. The embolic device of claim 18, wherein said first ring, said second ring, and said one or more intermediate rings comprise at least one complete ring and at least one ring comprised of two partial rings.
20. 20. The embolic device of claim 19, wherein the first ring, the second ring, and the one or more intermediate rings comprise two complete rings and one or more rings comprised of two partial rings.

Description

Embolic coil implantation system Cross Reference to Related Applications The present application claims priority from U.S. provisional patent application 63/295337 filed on 12 months 30 of 2021 and U.S. patent application 18/072767 filed on 1 month 12 of 2022, entitled "embolic coil implant System" (Embol ic Coi L IMP L ANT SYSTEM), the disclosures of which are incorporated herein by reference in their entirety. The application is a divisional application of patent application filed in China national intellectual property agency, application number 202211712831.2 and the name of 'embolic coil implantation system' at day 29 of 12 months 2022. Technical Field The present application relates generally to medical devices and methods of making and using medical devices. In particular, various embodiments of embolic devices or coil systems for deployment within the vasculature of a human body and methods of making and/or using the coil systems are described. Background Implants such as embolic devices are known in the treatment of vascular diseases such as aneurysms. Aneurysms are bulges or swellings formed on the wall of an artery in the brain or elsewhere in the human body. Cerebral aneurysms can cause severe pain and, if ruptured, can lead to fetal strokes. In the non-invasive or minimally invasive treatment of aneurysms, embolic devices may be placed in or at the aneurysm to isolate the aneurysm from the blood flow and/or promote thrombosis at the site. The placement of embolic devices is typically accomplished using a delivery system that directs the embolic device through the patient's vasculature to the location of the aneurysm. Once positioned at or within the aneurysm, the embolic device is detached from the delivery system by applying thermal or electrolytic energy or by activating a mechanical detachment mechanism. One widely used embolic device is a coil system comprising a soft helically wound coil. Three-dimensional microcoils have been developed for treating wide-necked aneurysms. For example, the three-dimensional microcoil has a primary or linear configuration when stretched in a delivery system, and assumes a secondary or three-dimensional configuration when deployed at a target site, for example. Three-dimensional microcoils can provide adequate coverage over the wide neck of an aneurysm. Three-dimensional microcoils may also provide a framework within the aneurysm in which subsequent coils may be placed. The three-dimensional microcoil is manufactured with a shape setting tool. One type of conventional shape setting tool has a configuration that can produce a simple "spiral" shaped microcoil. The end result is that the microcoil, once deployed within the aneurysm, reconfigures itself to conform to the three-dimensional dome shape of the aneurysm. However, there is no guarantee that the microcoil reconfigures itself to the intended 3D shape. Another type of conventional shape setting tool has a configuration that can produce a real 3D shape of microcoil, but is traditionally limited in increasing the length of the entire coil by the number of parts in the shape setting tool. That is, to produce longer lengths in the final microcoil product, more parts of the shape setting tool are required. Accordingly, there remains a need for improved coil systems and methods of manufacturing the same. It is desirable to provide a shape setting device or coil winding fixture that allows for the manufacture of 3D-shaped micro-coil systems with extended coil lengths of the same coil size. It is desirable to provide a 3D coil system that has structural stability and allows for more tightly packing aneurysms. Disclosure of Invention In one aspect, embodiments of the disclosure feature an embolic device. Generally, embodiments of embolic devices include microcoils having a primary configuration. The microcoil includes a first portion having a secondary configuration. The first portion in the secondary configuration includes one or more sets of rings. The loops of each of the one or more sets continuously intersect each other in a cycle, collectively forming a three-dimensional shape. In various embodiments of this aspect, the loops of each of the one or more groups intersect at a middle portion of the loops of each of the one or more groups along the loop. In various embodiments of this aspect, the one or more sets of rings include a first set of rings and a second set of rings overlaying the first set of rings, wherein the rings of the first set and the rings of the second set are generally concentric. The diameter of the second set of rings may be greater than the diameter of the first set of rings. In various embodiments of this aspect, the embolic device comprises two to fourteen sets of rings, wherein the two to fourteen sets of rings are generally concentric. The two to fourteen sets of loops may extend the length of the microcoil, ranging from 20 to 400mm. In various embodiments of this aspect, at least one