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CN-121971224-A - Hot compress material and preparation method thereof

CN121971224ACN 121971224 ACN121971224 ACN 121971224ACN-121971224-A

Abstract

The invention provides a hot compress material and a preparation method thereof, wherein the hot compress material comprises a heating medium and at least one temperature change indicator which is mixed in the heating medium and used for monitoring the temperature of the heating medium, the temperature change indicator is of a microcapsule structure with a core material and a wall material, the core material consists of an electron-donating leuco dye, an electron-withdrawing color-developing agent and a solvent, and the wall material consists of resin. According to the invention, the visual temperature change indicator is added into the heating medium, so that the temperature change of each part of the hot compress material can be intuitively observed, and people can intuitively recognize whether the hot compress material reaches the preset temperature or not, and whether the hot compress material has the same temperature or not.

Inventors

  • ZHANG BIN
  • XU DACHUANG
  • FANG YAN

Assignees

  • 北京博大格林高科技有限公司
  • 天津博大格致新材料技术有限责任公司

Dates

Publication Date
20260505
Application Date
20231113

Claims (10)

  1. 1. The hot compress material is characterized by comprising a heating medium and at least one temperature change indicator which is mixed in the heating medium and used for monitoring the temperature of the heating medium, wherein the temperature change indicator is of a microcapsule structure with a core material and a wall material, the core material consists of an electron-donating leuco dye, an electron-withdrawing color developing agent and a solvent, and the wall material consists of resin.
  2. 2. The heat dressing according to claim 1, wherein the heating medium is 90-99.99% and the temperature change indicator is 0.01-10% by mass.
  3. 3. The thermal dressing of claim 1, wherein the mass ratio of the electrokinetic leuco dye, the electron withdrawing developer and the solvent is 1:3-5:30-50.
  4. 4. The heat dressing of claim 1, wherein the electrogenic leuco dye comprises crystal violet lactone, 3-bis (1-ethyl-2-methylindol-3-yl) phthalide, 3-bis (1-butyl-2-methylindol-3-yl) phthalide, 3-bis (1-octyl-2-methyl-3-yl) phthalide, 3-diethylamino-7-methylfluoran, 3-diethylamino-7, 8-benzofluoran, 3- (N-ethyl-N-toluylamino) -7-methylfluoran, 3-diethylamino-6-methyl-7-chlorofluoran, 3-diethylamino-7-ethoxycarboxyfluoran, 3-dibutylamino-7-ethoxycarboxyfluoran, 3-diethylamino-6-methyl-7-phenylaminofluoran, 3-dibutylamino-6-methyl-7-phenylaminofluoran, 3- (N-ethyl-N-4-toluylamino) -6-methyl-7-phenylaminofluoran, 3- (N-ethyl-N-toluylamino) -7-phenylamino-ethyl-6-acetylamino-7-phenylfluoran, 3- (N-ethyl-N-4-toluylamino) -7-phenylamino-ethyl-6-phenyloxy-fluoran, 3-diethylamino-7-ethoxyfluoran One or more of 3- (4-dimethylamino) -3- (1-butyl-2-methyl-indol-3-yl) -6-dimethylaminophthalide or 3-diethylamino-6, 8-dimethylbutan-ne, 2-phenylamino-3-methyl-6-dibutylamino-fluoran, 3- (4-dimethylaminophenyl) -3- (4-methylethylamino-phenyl) -6-dimethylaminophenol, 1, 3-dimethyl-6-diethylamino-fluoran.
  5. 5. The thermal dressing of claim 1 wherein the electron withdrawing color developer comprises one or more of benzotriazoles, phenols, thiourea derivatives, aromatic carboxylic acids.
  6. 6. The heat dressing of claim 5, wherein the benzotriazole is 1-hydroxybenzotriazole, the phenols comprise bisphenol A, bisphenol S, 3-diallyl bisphenol S, 3-propoxybisphenol S or 3-propoxybisphenol S-201, the thiourea derivative is phenylthiourea, and the aromatic carboxylic acid comprises salicylic acid or salicylate and derivatives thereof.
  7. 7. The thermal dressing of claim 1, wherein the solvent is an ester solvent, a wax solvent, or an alcohol solvent.
  8. 8. The heat dressing of claim 7, wherein the ester solvent is an alkane carboxylate, dodecanoate or octyl palmitate, the wax solvent is a microcrystalline wax or insect wax, and the alcohol solvent is cetyl alcohol or tetradecyl alcohol.
  9. 9. The thermal dressing of claim 1 wherein the resin is one or more of an amino resin, an epoxy resin, or gelatin.
  10. 10. A preparation method of a heat dressing is characterized in that at least one temperature change indicator is mixed with a heating medium, heated to 45-55 ℃, stirred for 25-40 minutes, and cooled to room temperature to obtain the heat dressing.

Description

Hot compress material and preparation method thereof Technical Field The invention relates to the technical field of medical supplies, in particular to a hot compress material and a preparation method thereof. Background The hot compress treatment is to use heated dressing on affected part to expand local capillary vessel, increase its permeability, promote local exudation absorption, eliminate muscle spasm and increase soft tissue extensibility, so as to achieve the purpose of recovering joint function. The dressing is prepared from beeswax, medical paraffin, mineral mud, coarse material of parched salt, natrii sulfas granule, and wet-fomentation bag by heating to melt, and applying onto affected part, and is prepared by organically combining Chinese medicinal materials with hot compress medium to enhance cell membrane permeability, relieve tissue edema, and generate soft mechanical compression effect to soften and make skin elastic, improve skin, accelerate growth of epithelium, and promote healing of wound ulcer and fracture. However, due to the fact that the hot compress medium is poor in heat conduction performance, local high temperature is generated in the heating process of the medium, burn is generated on the hot compress part, so that a treatment effect cannot be achieved, a negative effect is obtained, especially the sensitivity of the skin of a diabetic patient to the ambient temperature is reduced, and the phenomenon is particularly serious. Accordingly, the prior art is subject to further development. Disclosure of Invention Aiming at various defects in the prior art, in order to solve the problems, a hot compress material and a preparation method thereof are provided, and the following technical scheme is provided: The hot compress material comprises a heating medium and at least one temperature change indicator which is mixed in the heating medium and used for monitoring the temperature of the heating medium, wherein the temperature change indicator is of a microcapsule structure with a core material and a wall material, the core material consists of an electron-donating leuco dye, an electron-withdrawing color developing agent and a solvent, and the wall material consists of resin. Further, the heating medium accounts for 90 to 99.99 percent and the temperature change indicator accounts for 0.01 to 10 percent according to the mass percent. Further, the mass dosage ratio of the electron-donating leuco dye, the electron-withdrawing color developing agent and the solvent is 1:3-5:30-50. Further, the method comprises the steps of, the electron donating leuco dyes include crystal violet lactone, 3-bis (1-ethyl-2-methylindol-3-yl) phthalide, 3-bis (1-butyl-2-methylindol-3-yl) phthalide, 3-bis (1-octyl-2-methyl-3-yl) phthalide, 3-diethylamino-7-methylfluoran, 3-diethylamino-7, 8-benzofluoran, 3- (N-ethyl-N-toluamino) -7-methylfluoran, 3-diethylamino-6-methyl-7-chlorofluoran, 3-diethylamino-7-ethoxycarboxyl fluoran, 3-dibutylamino-7-ethoxycarboxyl fluoran, 3-diethylamino-6-methyl-7-phenylaminofluoran, 3-dibutylamino-6-methyl-7-phenylaminofluoran, 3- (N-ethyl-N-4-toluamino) -6-methyl-7-phenylaminofluoran, 3- (N-ethyl-N-isopentyl) -7-methylbenzylamino-7-phenylamino-fluoran, 3-diethylamino-phenylamino-fluoran, one or more of 3- (4-dimethylamino) -3- (1-butyl-2-methyl-indol-3-yl) -6-dimethylaminophthalide or 3-diethylamino-6, 8-dimethylbutan-ne, 2-phenylamino-3-methyl-6-dibutylamino-fluoran, 3- (4-dimethylaminophenyl) -3- (4-methylethylamino-phenyl) -6-dimethylaminophenol, 1, 3-dimethyl-6-diethylamino-fluoran. Further, the electron withdrawing color developing agent comprises one or more of benzotriazole, phenol, thiourea derivative and aromatic carboxylic acid. Further, the benzotriazole is 1-hydroxybenzotriazole, the phenols comprise bisphenol A, bisphenol S, 3-diallyl bisphenol S, 3-propoxy bisphenol S or 3-propoxy bisphenol S-201, the thiourea derivative is phenylthiourea, and the aromatic carboxylic acid comprises salicylic acid or salicylate and derivatives thereof. Further, the solvent is an ester solvent, a wax solvent or an alcohol solvent. Further, the ester solvent is alkane carboxylic ester, dodecyl dodecanoate or octyl hexadecanoate, the wax solvent is microcrystalline wax or insect wax, and the alcohol solvent is cetyl alcohol or tetradecyl alcohol. Further, the resin is one or more of amino resin, epoxy resin or gelatin. In addition, the invention also provides a preparation method of the heat dressing, which comprises the following steps of mixing at least one temperature change indicator with a heating medium, heating to 45-55 ℃, stirring for 25-40 minutes, and cooling to room temperature to obtain the heat dressing. The beneficial effects are that: 1. according to the invention, the visual temperature change indicator is added into the heating medium, so that the temperature change of each part of the hot compress material can be intuitively observed, and people can intuitively recogn