CN-121971275-A - Flexible bionic eyelid rehabilitation system and rehabilitation training method

CN121971275ACN 121971275 ACN121971275 ACN 121971275ACN-121971275-A

Abstract

The invention belongs to the technical field of wearable medical instruments and rehabilitation, and provides a flexible bionic eyelid rehabilitation system and a rehabilitation training method, wherein the system comprises a flexible sensor array module, a flexible stretchable substrate and a sensing material; the system comprises a signal processing and control module, an electromagnetic driver module, a flexible magnetic patch module and a control module, wherein the signal processing and control module is used for acquiring dynamic characteristic parameters of the movement of the healthy eyelid and generating eyelid movement control instructions based on the dynamic characteristic parameters, the electromagnetic driver module is used for responding to the eyelid movement control instructions to generate a controllable magnetic field, and the flexible magnetic patch module can be pulled by non-contact magnetic force under the action of the controllable magnetic field to drive the patient's eyelid to execute follow-up operation synchronous with the movement of the healthy eyelid. The invention can realize functional closure or exercise assistance, construct a patient individual self-adaptive closed-loop mechanism of monitoring-feedback-regulation, and drive the affected eyelid to follow up by monitoring physiological signals of the exercise of the affected eyelid, thereby realizing auxiliary rehabilitation training which has more physiological adaptability and accords with the natural eye movement rule of human beings.

Inventors

LEI FENGYANG
TANG LIXUE
WANG ZIMENG
CAO XI
HOU SHENGPING

Assignees

北京市眼科研究所
首都医科大学
北京市糖尿病研究所(北京市糖尿病防治办公室)
首都医科大学附属北京同仁医院

Dates

Publication Date: 20260505
Application Date: 20260409

Claims (10)

1. A flexible, biomimetic eyelid rehabilitation system, comprising: The flexible sensor array module is configured to be attached to a user's lateral eye lid region in a noninvasive sensing manner and is used for monitoring physiological signals of the user's lateral eye lid movement in real time, wherein the flexible sensor array module comprises a flexible stretchable substrate and a sensing material arranged on the flexible stretchable substrate, the flexible stretchable substrate comprises Ecoflex silica gel, polydimethylsiloxane, thermoplastic polyurethane, SEBS (styrene-ethylene-butylene-styrene) and a polyimide composite film, and the sensing material comprises liquid metal ink, carbon nanotube composite material, MXene conductive ink, silver nanowires and conductive polymers; The signal processing and control module is in communication connection with the flexible sensor array module and is used for receiving and analyzing the physiological signals, acquiring dynamic characteristic parameters of the exercise of the healthy eyelid and generating eyelid exercise control instructions based on the dynamic characteristic parameters; An electromagnetic driver module, in communication with the signal processing and control module, for generating a controllable magnetic field in response to the eyelid movement control instructions; The flexible magnetic patch module is configured to be attached to the upper eyelid area of the affected side of the user, can be pulled by non-contact magnetic force under the action of the controllable magnetic field, and drives the eyelid of the affected side of the user to execute follow-up operation synchronous with the movement of the eyelid of the affected side.
2. The eyelid rehabilitation system of claim 1, wherein the flexible sensor array module is a single channel, a fiber, a two-dimensional array arrangement, or a three-dimensional array arrangement.
3. The eyelid rehabilitation system of claim 1, wherein the electromagnetic driver module comprises a steering engine and angular displacement output is provided by the steering engine.
4. The eyelid rehabilitation system of claim 1, wherein the flexible magnetic patch module comprises a flexible encapsulation layer and a magnetically responsive element encapsulated within the flexible encapsulation layer, the magnetically responsive element configured to be movable under the controllable magnetic field to assist the patient's eyelid in performing the follow-up procedure.
5. The eyelid rehabilitation system of claim 4, wherein the flexible packaging layer comprises medical grade silicone, ecoflex silicone, thermoplastic polyurethane film, medical breathable adhesive film; The magnetic response element comprises a miniature NdFeB permanent magnet, a samarium cobalt SmCo magnet, flexible magnetic rubber, a magnetic fluid capsule and a soft magnetic sheet.
6. The eyelid rehabilitation system of claim 1, further comprising a wearable carrier, the electromagnetic driver module, the signal processing and control module being integrated on the wearable carrier.
7. The eyelid rehabilitation system of claim 6, wherein the wearable carrier is a spectacle frame structure customized to the contour of a user's face.
8. A flexible bionic eyelid rehabilitation training method, characterized in that the flexible bionic eyelid rehabilitation training method is realized by adopting the flexible bionic eyelid rehabilitation system according to any one of claims 1 to 7, and comprises the following steps: step S100, monitoring physiological signals of the eye lid exercise of the user on the healthy side in real time through a non-invasive sensing mode of skin contact; step S200, analyzing the physiological signal to obtain dynamic characteristic parameters of the eye lid exercise on the healthy side, and generating eyelid exercise control instructions based on the dynamic characteristic parameters; Step S300, a controllable magnetic field is generated based on the eyelid movement control instruction, and the eyelid of the affected side of the user is electromagnetically driven to follow up in a non-contact mode through magnetic traction; step 400, the step 100 is cycled to the step 300 to perform closed-loop regulation and control of the eyelid rehabilitation training of the self-adaptive user based on the real-time feedback of the physiological signals.
9. The eyelid rehabilitation training method according to claim 8, wherein in the step S200, the dynamic characteristic parameters include a closing motion start-stop time point, a motion peak intensity, a motion change trend, and a motion intention of the healthy side eyelid.
10. The eyelid rehabilitation training method according to claim 9, wherein in the step S200, the eyelid movement control command includes an action timing, a magnetic force action intensity and an action pattern.

Description

Flexible bionic eyelid rehabilitation system and rehabilitation training method Technical Field The application relates to the technical field of wearable medical instruments and rehabilitation, in particular to a flexible bionic eyelid rehabilitation system and a rehabilitation training method. Background Current rehabilitation and adjuvant treatment means for severe ptosis (Ptosis) and eyelid movement disorder (Eyelid Motor Disorder) are mainly divided into two major categories of surgical operation and adjuvant treatment devices, but the following obvious disadvantages still exist: 1) The invasive performance is strong/the dynamic performance is poor, the invasive performance of the traditional eyelid corrector or the surgical suture operation is strong, and the dynamic adjustment is difficult to be carried out according to the needs after the operation. 2) The existing eyelid opening and closing control device is mostly based on preset rhythms or central instruction rules, lacks an individual regulation mechanism, is poor in patient compliance, is stiff in movement mode and does not accord with natural physiological rules of human bodies. This lack of design of individual regulatory mechanisms results in poor compliance when worn by the patient. More importantly, the eyelid movement pattern generated by the method is mechanically limited by program setting, and can not simulate smooth and cooperative movement rules of human eyes in natural physiological states, so that the purpose of bionic rehabilitation or natural assistance can not be achieved. 3) The eye movement tracking system has no closed-loop control capability, and the camera type eye movement tracking system can partially identify eye movement behaviors. But has the fundamental defect that physiological deformation signals (such as periocular muscle deformation, periocular electromyographic signals and the like) of eyelid dynamic units (such as blepharo levator, orbicularis oculi and cooperative muscle groups thereof) cannot be directly obtained in real time. The system lacks closed-loop control capability based on physiological feedback, namely, the actual working state of muscles cannot be monitored in real time, and the auxiliary device is driven finely according to the actual working state, so that real bionic, accurate and real-time physiological-mechanical closed-loop regulation and control are difficult to realize. To solve at least one of the above problems, a related art has developed various systems for controlling eyelid closure, for example, a system for micro-mechanical treatment of a single-sided eyelid closure disorder is disclosed in patent application publication No. CN107307977a, in which an opening and closing angle of a healthy-sided eyelid is obtained through an information acquisition device and is sent to a terminal processor, the terminal processor processes angular information and transmits a signal to a micro-mechanical device, so that the micro-mechanical device drives the affected-sided eyelid to move, and symmetrical movements can be completed at the same angle by the affected-sided eyelid and the healthy-sided eyelid. Thereby, the problem of unilateral eyelid closure obstruction is solved. And an information acquisition device. The information acquisition device and the terminal processor can be embedded in a human body, can also be arranged on external wearing equipment, and are various in use mode and more convenient to use. But this system requires surgical embedding of sensing devices, micromechanical devices, etc. inside the eyelid and on the orbital bone, an invasive approach. And, through miniature motor drive pivot and sleeve pipe, the support of implantation eyelid is pulled mechanically to open and shut the eyelid, is a direct physical contact drive. The whole system comprises precise mechanical structures such as a miniature motor, a transmission shaft, a fixed support and the like, and requires complex surgical operation implantation and has extremely high requirements on biocompatibility. For example, patent application document CN117815033a discloses a wearable device, a method and an electronic device for controlling closing of a single eyelid, where the wearable device includes an acquisition device, a processing device, a stepping motor, an up-eyelid adjuster and a down-eyelid adjuster, the acquisition device and the stepping motor are both connected with the processing device, the acquisition device is disposed on the eyelid-care side, the stepping motor, the up-eyelid adjuster and the down-eyelid adjuster are disposed on the eyelid-care side, a uniform end of the up-eyelid adjuster and the down-eyelid adjuster is fixed on the stepping motor, and one end of the up-eyelid adjuster is suspended, the acquisition device is used for acquiring opening and closing state information of the eyelid and sending the opening and closing state information to the processing device, the processing device is use