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CN-121971330-A - A composition for relieving and inhibiting bacteria and its application in shower gel

CN121971330ACN 121971330 ACN121971330 ACN 121971330ACN-121971330-A

Abstract

The invention relates to a soothing and antibacterial composition and application thereof in shower gel, and belongs to the technical field of cosmetics. The slow-release antibacterial composition comprises a fermentation substrate and a fermentation strain, wherein the fermentation substrate comprises a gulfweed extract, a horse chestnut extract and a hemerocallis fulva extract, the mass ratio of the gulfweed extract, the horse chestnut extract and the hemerocallis fulva extract in the fermentation substrate is 1:0.1-0.7:3-6, and the fermentation strain comprises a bailey spore yeast. The soothing and antibacterial composition obtained by the fermentation substrate and the fermentation strain has the advantages of remarkably inhibiting the activity of hyaluronidase and the activity of malassezia and propionibacterium acnes, and can remarkably improve the soothing and antibacterial effects of the shower gel when being applied to the shower gel.

Inventors

  • LI BO
  • LIANG HANFEN

Assignees

  • 珠海威生化妆品有限公司

Dates

Publication Date
20260505
Application Date
20260129

Claims (10)

  1. 1. The composition is characterized by comprising a fermentation substrate and a fermentation strain, wherein the fermentation substrate comprises a gulfweed extract, a horse chestnut extract and a hemerocallis fulva extract, the mass ratio of the gulfweed extract to the horse chestnut extract to the hemerocallis fulva extract in the fermentation substrate is 1:0.1-0.7:3-6, and the fermentation strain comprises a bailey spore yeast.
  2. 2. The composition of claim 1, wherein the method of preparing the composition comprises the steps of: S1, uniformly mixing a gulfweed extract, a horse chestnut extract and a hemerocallis chinensis flower extract to obtain mixed powder; S2, uniformly mixing the mixed powder and the culture medium powder in a mass ratio of 1:2-5 to obtain a fermentation substrate; S3, preparing a fermentation substrate into a culture solution with the weight percent of 8-12% by using deionized water, inoculating a strain solution into the culture solution, fermenting for 12-16 hours, sterilizing after the fermentation is finished, filtering insoluble substances, and freeze-drying to obtain the slow and antibacterial composition.
  3. 3. The composition of claim 2, wherein the media powder comprises at least one of a strain-growable media.
  4. 4. The composition of claim 3, wherein the media powder comprises YPD media.
  5. 5. The composition of claim 2, wherein the strain liquid is a strain liquid of Mortierella bainieri, the viable count is 1×10 8 CFU/mL, and the preservation number of the Mortierella bainieri is CCTCCNO: M2023647.
  6. 6. The composition according to claim 2, wherein the seed amount in the step S3 is 5-8v/v%, the fermentation temperature is 25-32 ℃, and the fermentation initiation pH is 4.5-5.5.
  7. 7. Use of a composition according to any one of claims 1 to 6 for the preparation of a cosmetic product having soothing and bacteriostatic efficacy.
  8. 8. The use according to claim 7, wherein the cosmetic formulation comprises any one of an emulsion, a cream, a gel, a mask, a spray.
  9. 9. A shower gel having soothing and antibacterial effects, characterized in that it comprises the soothing and antibacterial composition according to any one of claims 1 to 6.
  10. 10. The shower gel of claim 9, wherein said shower gel further comprises a shower gel acceptable adjuvant.

Description

A composition for relieving and inhibiting bacteria and its application in shower gel Technical Field The invention relates to the technical field of cosmetics, in particular to a soothing and antibacterial composition and application thereof in shower gel. Background With the development of socioeconomic performance and the improvement of consumer living standards, the personal care cosmetic market is undergoing a profound transition from basic cleaning to functional, experiential, and ingredient-wise. Especially in the field of bath products, the demands of consumers are far beyond simple cleaning of sweat stains, and pursuing the relief of body and mind, the healing of emotion and the lasting moistening and health state of skin after washing in the process of bath. In recent years, the problems of skin sensitivity, dryness and itching caused by environmental pressure, irregular work and rest and the like are increasingly common, and the skin surface in daily life is easy to be infected with and grow microorganisms such as bacteria, fungi and the like, so that a series of problems such as acnes, red rashes, peculiar smell and even infection can be caused. Thus, there is an urgent and tremendous need in the marketplace for bathing products that have both excellent soothing and bacteriostatic effects. To cope with this market demand, the cosmetic industry has made a number of technical attempts. In terms of achieving bacteriostatic efficacy, traditional approaches have relied primarily on the addition of chemically synthesized preservatives or antimicrobial agents (e.g., certain quaternary ammonium salts, triclosan, etc.). However, the potential problems of such ingredients are increasingly highlighted by the fact that long-term use may destroy the microecological balance of the skin surface, lead to drug resistance, even cause adverse reactions such as skin irritation, allergy and the like, and are contrary to the current consumption concepts of ' pure beauty and ' mild and no irritation '. Therefore, the development of natural-derived alternative bacteriostatic components is an important research direction in the industry. In the application of natural ingredients, single plant extracts, such as tea tree essential oil, calendula extract, etc., are widely used due to their natural antibacterial or soothing properties. However, a large number of practices show that single components have limited efficacy, single action targets and higher action concentration, and are difficult to deal with complicated skin problems. Subsequently, technology has evolved to physically compound various plant extracts, with the expectation that synergistic objectives are achieved by component combinations. For example, the A extract having antibacterial effect is simply mixed with the B extract having anti-inflammatory and soothing effects. However, in most cases, the physical compounding is only linear superposition of component functions, the molecular structure and bioavailability of each active component are not changed fundamentally, the synergistic effect of the active components often cannot reach the expected effect of 1+1>2, and the efficacy improvement range is limited. The introduction of biological fermentation technology provides a new idea for enhancing the efficacy of natural products. Through the metabolism of specific microorganisms, macromolecular substances in plant raw materials can be decomposed into micromolecular active substances which are easier to be absorbed by skin, and new beneficial metabolites can be generated, so that the biological activity of the final product is obviously improved. However, the application effect of this technique is highly dependent on a precise and interrelated system, and any link deviation may lead to failure. First, the choice and ratio of fermentation substrates is the basis. Different plant combinations are used as substrates, and the nutrients such as proteins, saccharides and the like contained in the plant combinations determine the growth efficiency of microorganisms, and the characteristic active ingredients contained in the plant combinations are sources of target efficacy. If the substrates are not properly combined or in an inconsistent ratio, not only may the metabolic pathways of the microorganism deviate from the intended, but also no desirable synergistic effect may be produced. Secondly, the screening of the fermentation strains is the core. Different microbial strains (even strains of the same species of different accession numbers) may have different metabolic properties, enzyme-producing capacity and secretion levels of active products. The selection of a specific strain with high efficiency and stability is the key for realizing high-efficiency transformation. Furthermore, fermentation process parameters (such as substrate concentration, inoculum size, temperature, pH, fermentation time, etc.) are ensured. These parameters together constitute the microe