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CN-121971331-A - Oil-control antibacterial composition containing o-cymene-5-ol, preparation method and application thereof

CN121971331ACN 121971331 ACN121971331 ACN 121971331ACN-121971331-A

Abstract

The invention belongs to the technical field of cosmetics, and particularly relates to an oil-control antibacterial composition containing o-cymene-5-ol, a preparation method and application thereof. An oil-controlling antibacterial composition containing o-cymene-5-ol comprises, by mass, 5-15 parts of o-cymene-5-ol, 1-10 parts of black willow bark extract, 5-15 parts of sake yeast extract, 1-10 parts of camellia extract and 1-10 parts of coffee wasabi extract. The invention uses the composite technology of enzymolysis pretreatment and supercritical carbon dioxide extraction, can fully extract active ingredients on the premise of protecting the structures of the active ingredients from being damaged, remarkably enhances the antibacterial effect, realizes the synergistic effect of the oil control effect by scientifically compounding the components, improves the oil control rate by the synergistic effect of the components, has longer oil control effect, and can effectively improve the problems of greasiness, floodlight and the like of skin.

Inventors

  • LI YALIAN

Assignees

  • 广州科丽德日化科技有限公司

Dates

Publication Date
20260505
Application Date
20260203

Claims (10)

  1. 1. The oil-control antibacterial composition containing the o-cymene-5-ol is characterized by comprising the following components, by mass, 5-15 parts of the o-cymene-5-ol, 1-10 parts of a black willow bark extract, 5-15 parts of a sake yeast extract, 1-10 parts of a camellia extract and 1-10 parts of a coffee wasabi extract.
  2. 2. The oil-control antibacterial composition containing o-cymene-5-ol according to claim 1, which is characterized by comprising the following components, by mass, 8-12 parts of o-cymene-5-ol, 5-8 parts of black willow bark extract, 6-10 parts of sake yeast extract, 4-7 parts of camellia extract and 3-6 parts of coffee wasabi extract.
  3. 3. The oil control antibacterial composition containing o-cymene-5-ol according to claim 2, wherein the preparation method of the black willow bark extract comprises the following steps: (1) Cleaning black willow bark, drying to constant weight, and pulverizing to obtain black willow bark powder; (2) Mixing black willow bark powder with deionized water, uniformly stirring, regulating the pH value of a system to 4.5-5.5, adding compound enzyme, carrying out enzymolysis at a constant temperature of 45-50 ℃ for 2.5-3.5 hours, and inactivating enzyme after the enzymolysis is finished to obtain an enzymolysis solution; (3) Placing the enzymolysis liquid in a rotary evaporator, and concentrating to 1/5-1/4 of the original volume to obtain concentrated liquid; (4) Placing the concentrated solution in a supercritical extraction kettle, adding ethanol as entrainer, extracting, separating CO 2 and the extractive solution by a reduced pressure separation kettle after extraction to obtain crude extractive solution; (5) Freeze drying the filtered extract to constant weight, and pulverizing to obtain black willow bark extract.
  4. 4. An o-cymene-5-ol-containing oil control antibacterial composition according to claim 3, wherein the complex enzyme is formed by mixing cellulase and hemicellulase.
  5. 5. The oil-controlling and antibacterial composition containing o-cymene-5-ol according to claim 4, wherein the complex enzyme is prepared by mixing cellulase and hemicellulase according to a mass ratio of (1.8-2.2): 1.
  6. 6. An o-cymene-5-ol-containing oil-controlling antibacterial composition according to claim 3, wherein the supercritical extraction kettle is set to an extraction pressure of 30-35MPa, an extraction temperature of 40-45 ° C, CO 2 flow of 20-25L/h, and an extraction time of 2-3h.
  7. 7. An o-cymene-5-ol-containing oil-controlling antibacterial composition according to claim 3, wherein the separation pressure is 5-8MPa and the separation temperature is 30-35 ℃.
  8. 8. An o-cymene-5-ol-containing oil control antibacterial composition according to claim 3, wherein the complex enzyme is added in an amount of 0.8% -1.2% by mass of the black willow bark powder.
  9. 9. A method for preparing the o-cymene-5-ol-containing oil control antibacterial composition according to any one of claims 1 to 8, which is characterized by comprising the step of uniformly mixing the o-cymene-5-ol, black willow bark extract, sake yeast extract, camellia extract and coffee yellow extract to obtain the o-cymene-5-ol-containing oil control antibacterial composition.
  10. 10. Use of an o-cymene-5-ol-containing oil-controlling antibacterial composition according to any one of claims 1 to 8 in the preparation of a cosmetic.

Description

Oil-control antibacterial composition containing o-cymene-5-ol, preparation method and application thereof Technical Field The invention belongs to the technical field of cosmetics, and particularly relates to an oil-control antibacterial composition containing o-cymene-5-ol, a preparation method and application thereof. Background With the acceleration of the life rhythm, the change of the dietary structure and the influence of environmental factors, the oily skin problem is increasingly common, and the oily skin is characterized by vigorous secretion of grease on the surface of the skin, and is also easy to cause skin problems such as pore blockage, acne, folliculitis and the like. The core cause of the phenomenon is that the sebaceous gland hypersecretion causes the accumulation of a large amount of grease, simultaneously the microecology on the surface of the skin is unbalanced, pathogenic bacteria such as propionibacterium acnes, staphylococcus aureus and the like are propagated in a large amount, and the interaction of the two causes the aggravation of skin problems. Therefore, the development of a composition with excellent oil control effect and high-efficiency antibacterial performance becomes a research hot spot in the fields of cosmetics and skin care products. At present, in the prior art, the nursing products aiming at oily skin are mostly developed around the single efficacy of oil control or bacteriostasis, or the combination of the oil control and the bacteriostasis is tried, but the technical pain point that the excellent oil control and the bacteriostasis effect cannot be simultaneously realized exists generally, and the core components of the existing oil control products are mostly adsorption substances or grease regulating components. The oil regulating component can inhibit the activity of sebaceous glands to a certain extent, but has weak antibacterial capability, and is difficult to avoid inflammatory reactions such as acne when the number of pathogenic bacteria on the surface of the skin is large. The existing antibacterial products mostly adopt chemical bactericides or single plant extracts. Although the chemical bactericide has remarkable antibacterial effect, the chemical bactericide has stronger irritation, can easily damage skin barrier after long-term use, even causes further unbalance of skin microecology to aggravate grease secretion disorder, has limited antibacterial activity of single plant extract, lacks specific oil control components, cannot solve the core problem of vigorous grease secretion, and is difficult to realize the synergistic improvement effect of oil control and bacteriostasis. In order to overcome the defect of single efficacy, some prior art attempts to compound oil control components and antibacterial components, but the compound system cannot realize synergistic effect due to improper component selection, unbalanced proportion or lag in preparation process of key components, and still cannot achieve excellent oil control and antibacterial effects at the same time. The specific defects include (1) poor component suitability, namely, the blind mixing of oil control and bacteriostasis components of part of the compound product, and no consideration of interaction among the components. Although partial plant extracts have certain oil control and bacteriostasis potential, the extraction process of the plant extracts is not optimized in the prior art, so that the active ingredients in the extracts are low in content and poor in purity, and cannot fully play a role. (2) The proportion of the components of the existing compound product is mostly empirical proportion, and the system optimization is not carried out. The skin is in a greasy state because the bacteria are inhibited but the problem of grease secretion is not solved, or the excessive antibacterial component and the insufficient antibacterial component cause that the bacteria cannot be inhibited while the temporary oil control is carried out, so that the skin inflammation is easy to be repeatedly induced. Therefore, the composition which has good ingredient adaptability, scientific proportion and high activity of key ingredients and can realize high-efficiency oil control and strong-efficiency bacteriostasis is developed, and has important practical significance and market value. Disclosure of Invention The invention aims to provide an oil-control antibacterial composition containing o-cymene-5-ol, a preparation method and application thereof. In order to achieve the above object, the present invention provides the following technical solutions: An oil-controlling antibacterial composition containing o-cymene-5-ol comprises, by mass, 5-15 parts of o-cymene-5-ol, 1-10 parts of black willow bark extract, 5-15 parts of sake yeast extract, 1-10 parts of camellia extract and 1-10 parts of coffee wasabi extract. The preparation method of the black willow bark extract comprises the following steps: (1) Clean