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CN-121971335-A - Plant composition with toxicity reducing and synergistic effects for relieving and preventing sun, and preparation method and application thereof

CN121971335ACN 121971335 ACN121971335 ACN 121971335ACN-121971335-A

Abstract

The invention provides a plant composition with toxicity reducing and synergistic effects for relieving and preventing sun, and a preparation method and application thereof, and belongs to the technical field of medicines. The preparation comprises the following raw materials, by weight, 5-8 parts of inula helenium extract, 10-15 parts of chamomile extract, 4-6 parts of gentian extract and 25-40 parts of schizophyllan. The invention prepares a composition through the precise combination of four active ingredients and scientific process treatment, which remarkably improves the relieving effect on skin injury caused by the stimulation of a sun-screening agent and ultraviolet irradiation, remarkably improves the resisting effect of ultraviolet light on the skin injury, can replace part of chemical sun-screening agents, lightens the toxicity of cosmetics, realizes the synergistic effect of 'attenuation+high-efficiency ultraviolet resistance+relieving restoration', and provides a new technical scheme for developing cosmetics with low-toxicity and high-efficiency ultraviolet resistance and sun-screening bidirectional relieving restoration.

Inventors

  • LI ZHUOHANG
  • LI CHENCHEN
  • ZHANG PENG
  • SHEN YALI
  • CHEN BIN

Assignees

  • 成都青山利康药业股份有限公司
  • 中华全国供销合作总社南京野生植物综合利用研究所
  • 南京野生植物综合利用研究设计所

Dates

Publication Date
20260505
Application Date
20260211

Claims (10)

  1. 1. The composition is characterized by comprising, by weight, 5-8 parts of inula helenium extract, 10-15 parts of chamomile extract, 4-6 parts of gentian extract and 25-40 parts of schizophyllan.
  2. 2. The composition according to claim 1, which comprises the following raw materials, by weight, 5 parts of inula helea extract, 15 parts of chamomile extract, 6 parts of gentian extract and 30 parts of schizophyllan.
  3. 3. The composition of claim 1, wherein the composition comprises, by mass, 5-8% of inula helea extract, 10-15% of chamomile extract, 4-6% of gentian extract, 25-40% of schizophyllan, 5-8% of an alcoholic solvent and the balance of water.
  4. 4. The composition according to claim 3, which comprises the following raw materials, by mass, 5% of inula helea extract, 15% of chamomile extract, 6% of gentian extract, 30% of schizophyllan, 5% of an alcohol solvent and the balance of water.
  5. 5. The composition according to any one of claims 3 to 4, wherein the alcohol solvent is at least one of propylene glycol, 1, 3-propylene glycol, butylene glycol, dipropylene glycol, and glycerin.
  6. 6. The composition of any one of claims 1-4, wherein the inula koraiensis extract, the chamomile extract and the gentian root extract are water extract, ethanol extract or ethanol-water extract of inula koraiensis, chamomile and gentian root kernel, respectively, and the schizophyllan is prepared by liquid fermentation, separation and purification and drying of schizophyllan, and the schizophyllan strain has a preservation number of CGMCC No.5.776.
  7. 7. A method of preparing the composition of any one of claims 1 to 6, comprising the steps of: (1) Placing Inula facing flower extract, flos Matricariae Chamomillae extract, radix Gentianae extract, schizophyllan into a sterile mixing tank; (2) Adding an alcohol solvent and water into a mixing tank, and uniformly stirring and mixing to obtain a composite system; (3) Homogenizing the composite system to obtain the composition.
  8. 8. Use of the composition according to any one of claims 1 to 6 for the preparation of cosmetics.
  9. 9. The use according to claim 8, characterized in that the cosmetic is a cosmetic that relieves irritation or damage caused by sunscreens, and/or is resistant to ultraviolet light.
  10. 10. The use according to claim 8, wherein the composition is added to the cosmetic in an amount of 0.5% -5.0% of the total mass of the cosmetic.

Description

Plant composition with toxicity reducing and synergistic effects for relieving and preventing sun, and preparation method and application thereof Technical Field The invention belongs to the technical field of medicines, and particularly relates to a plant composition with toxicity reducing and synergistic effects for relieving and sun-screening, and a preparation method and application thereof. Background The existing sun-screening cosmetic has the core technical scheme mainly comprising three types, namely a pure physical sun-screening scheme, which takes inorganic particles such as titanium dioxide, zinc oxide and the like as core sun-screening components, realizes protection by reflecting and scattering ultraviolet rays, but the particles of the substances have larger particle sizes, easily cause thick and heavy product quality, obvious whitening, sticky and airtight skin feel after being smeared, slow film forming speed, easy occurrence of mud rubbing phenomenon, weaker protection capability on long-wave ultraviolet rays (UVA), difficulty in realizing full-band efficient protection by single use, and influence on sun-screening stability possibly due to particle aggregation, a pure chemical sun-screening scheme, which adopts organic sun-screening agents such as ethylhexyl methoxycinnamate, benzophenone-3 and the like, realizes protection by absorbing ultraviolet rays and converting the ultraviolet rays into heat energy, has higher protection efficiency, but the chemical sun-screening agents have certain irritation to skin and possibly cause skin discomfort after long-term or high-dose use, and the two types of components are compounded by a physical-chemical compound sun-screening scheme, so that the problems of irritation and poor protection are still existed in the formula. With the importance of consumers on skin safety, plant extract components gradually become research hot spots due to the characteristics of mild and low irritation, and are widely used for replacing partial chemical sunscreens or formulas for relieving sunscreens irritation. For example, by adding a single plant extract component such as chamomile extract, aloe vera extract, for relieving irritation of chemical sunscreens or UV-induced skin discomfort. However, these prior arts all surround the core requirement of "uv protection", and the improvement of mildness by single plant extract components, and do not form a synergistic combination design for "high-efficiency protection+mildness", and the synergistic effects of "reducing the dosage of chemical sunscreens, reducing the toxicity thereof, and relieving uv damage" cannot be achieved. Therefore, the key technical defects of the existing sunscreen cosmetics in the aspects of ultraviolet resistance protection and relief repair are overcome, and the development of the sunscreen cosmetics which can achieve both protection synergy and bidirectional repair is a core problem in the field. Disclosure of Invention The invention aims to provide a plant composition with attenuation and synergy for relieving and sun-screening, and a preparation method and application thereof. The invention provides a composition which comprises, by weight, 5-8 parts of inula helenium extract, 10-15 parts of chamomile extract, 4-6 parts of gentian extract and 25-40 parts of schizophyllan. The composition according to claim 1, which comprises the following raw materials, by weight, 5 parts of inula helea extract, 15 parts of chamomile extract, 6 parts of gentian extract and 30 parts of schizophyllan. The preparation method comprises the following raw materials, by mass, 5-8% of inula helenium extract, 10-15% of chamomile extract, 4-6% of gentian extract, 25-40% of schizophyllan, 5-8% of alcohol solvent and the balance of water. Further, the composition comprises the following raw materials, by mass, 5% of inula sonchifolia extract, 15% of chamomile extract, 6% of gentian extract, 30% of schizophyllan, 5% of alcohol solvent and the balance of water. Further, the alcohol solvent is at least one of propylene glycol, 1, 3-propylene glycol, butanediol, dipropylene glycol and glycerol. Further, the inula helveticus extract, the chamomile extract and the gentian root extract are respectively water extract, ethanol extract or ethanol-water extract of inula helveticus, chamomile and gentian root cores, the schizophyllan is prepared by liquid fermentation, separation and purification and drying of schizophyllan, and the schizophyllan strain has a preservation number of CGMCC No.5.776. The invention also provides a preparation method of the composition, which comprises the following steps: (1) Placing Inula facing flower extract, flos Matricariae Chamomillae extract, radix Gentianae extract, schizophyllan into a sterile mixing tank; (2) Adding an alcohol solvent and water into a mixing tank, and uniformly stirring and mixing to obtain a composite system; (3) Homogenizing the composite system to obtain the composition. Th