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CN-121971362-A - A cosmetic with antiaging and cell metabolism accelerating effects, and its preparation method

CN121971362ACN 121971362 ACN121971362 ACN 121971362ACN-121971362-A

Abstract

The invention belongs to the technical field of cosmetics, in particular to a cosmetic for resisting aging and accelerating cell metabolism and a preparation method thereof, and the technical scheme is that the cosmetic for resisting aging and accelerating cell metabolism comprises the following components: 0.0001 to 0.005 percent of cell growth factor compound, 0.0001 to 0.003 percent of small molecule peptide compound, 0.1 to 5 percent of plant stem cell extract, 1 to 10 percent of grease, 1 to 10 percent of surfactant, 1 to 15 percent of humectant, 0.1 to 1 percent of antioxidant, 0.1 to 3 percent of pH regulator, 0.05 to 0.2 percent of preservative and the balance of deionized water; the invention promotes the proliferation of cells in epidermis and dermis layers through cell growth factors, small molecular peptides regulate cell metabolism and promote collagen synthesis, and plant stem cell extracts are rich in polyphenol active ingredients, can activate the activity of endogenous stem cells of skin, and obviously promote the metabolism rate and anti-aging effect of skin cells through the synergistic effect of different action paths.

Inventors

  • Miao Jianheng
  • SHI QINGXIN
  • SHEN JIE
  • ZHENG LU
  • YE QINGLI
  • Wan Tongxuan
  • CHEN JING
  • GU WEIFENG

Assignees

  • 丝薇茜(上海)生物技术有限公司

Dates

Publication Date
20260505
Application Date
20260325

Claims (10)

  1. 1. A cosmetic for resisting aging and accelerating cell metabolism is characterized by comprising the following components of 0.0001-0.005% of cell growth factor compound, 0.0001-0.003% of small molecule peptide compound, 0.1-5% of plant stem cell extract, 1-10% of grease, 1-10% of surfactant, 1-15% of humectant, 0.1-1% of antioxidant, 0.1-3% of pH regulator, 0.05-0.2% of preservative and the balance of deionized water.
  2. 2. The cosmetic for resisting aging and accelerating cellular metabolism according to claim 1, wherein the mass ratio of the cell growth factor complex to the small molecule peptide complex is 1:1-1:2.
  3. 3. The cosmetic for resisting aging and accelerating cell metabolism according to claim 1, wherein the cell growth factor compound comprises 20% -50% of keratinocyte growth factor, 20% -50% of acidic fibroblast growth factor and 20% -50% of epidermal growth factor.
  4. 4. The cosmetic for resisting aging and accelerating cell metabolism according to claim 1, wherein the small molecule peptide complex comprises 20-50% of palmitoyl tripeptide, 5-50% of acetyl tetrapeptide and 20-50% of cupreotide.
  5. 5. The cosmetic for anti-aging and cell metabolism acceleration according to claim 1, wherein the plant stem cell extract is an extract obtained by plant callus culture, and the plant is at least one of apple, grape or rose.
  6. 6. The cosmetic for anti-aging and cell metabolism acceleration according to claim 1, wherein the oil is at least one selected from squalane, caprylic/capric triglyceride, jojoba oil and polydimethylsiloxane.
  7. 7. The cosmetic for resisting aging and accelerating cell metabolism according to claim 1, wherein the surfactant is at least one selected from the group consisting of cetostearyl ether-2, cetostearyl ether-21, tween 20 and tween 80, and the surfactant is at least one selected from the group consisting of cetostearyl ether-2, cetostearyl ether-21, tween 20 and tween 80.
  8. 8. The cosmetic for resisting aging and accelerating cellular metabolism according to claim 1, wherein the humectant is at least one selected from the group consisting of sodium hyaluronate, glycerol, propylene glycol, and trimethylglycine, and the antioxidant is at least one selected from the group consisting of metallothionein, superoxide dismutase, vitamin C, and vitamin E.
  9. 9. The cosmetic for resisting aging and accelerating cell metabolism according to claim 1, wherein the pH regulator is a citric acid-sodium citrate buffer pair or a lactic acid-sodium lactate buffer pair, and the preservative is at least one selected from methyl paraben, propyl paraben and bis (hydroxymethyl) imidazolidinyl urea.
  10. 10. A method for preparing a cosmetic for anti-aging and accelerating cell metabolism according to claim 1, characterized by comprising the following steps: Heating grease and a surfactant to 75-85 ℃, stirring until the grease and the surfactant are completely dissolved, and cooling to 40-45 ℃ to obtain an oil phase; Dissolving the cell growth factor compound, the small molecule peptide compound, the plant stem cell extract and the antioxidant with deionized water to obtain an active substance aqueous solution; Dissolving a humectant, a pH regulator and a preservative in deionized water to obtain an auxiliary water phase; Adding the active substance aqueous solution into the oil phase, and stirring until the active substance aqueous solution is uniform to obtain a mixed system; And fifthly, adding the auxiliary water phase into the mixed system, and uniformly stirring to obtain a finished product.

Description

A cosmetic with antiaging and cell metabolism accelerating effects, and its preparation method Technical Field The invention belongs to the technical field of cosmetics, and particularly relates to a cosmetic capable of resisting aging and accelerating cell metabolism and a preparation method thereof. Background With the wide application of biotechnology in the cosmetic field, bioactive components are becoming research hotspots for high-end skin care products. The cell growth factor can promote proliferation and differentiation of epidermal cells and fibroblasts, accelerate synthesis of collagen, and has remarkable effects on repairing damaged skin and delaying aging. The small molecule peptide can simulate the biological activity of natural polypeptide, regulate and control skin cell metabolism, promote collagen regeneration and strengthen skin elasticity. However, the combination of the growth factors and the peptides in the prior art has a certain effect, but has the defects that the stability of the active ingredients in the preparation is difficult to maintain for a long time, the synergistic effect of a single or double-component system on deep skin repair and anti-aging is limited, and the lack of the ingredients capable of continuously activating the activity of skin stem cells cannot radically delay skin aging. Disclosure of Invention In order to solve the problems, the invention provides a cosmetic for resisting aging and accelerating cell metabolism. The invention provides a cosmetic for resisting aging and accelerating cell metabolism, which comprises 0.0001-0.005% of cell growth factor compound, 0.0001-0.003% of small molecule peptide compound, 0.1-5% of plant stem cell extract, 1-10% of grease, 1-10% of surfactant, 1-15% of humectant, 0.1-1% of antioxidant, 0.1-3% of pH regulator, 0.05-0.2% of preservative and the balance of deionized water. Further, the mass ratio of the cell growth factor complex to the small molecule peptide complex is 1:1-1:2. Further, the cell growth factor compound comprises 20% -50% of keratinocyte growth factor, 20% -50% of acidic fibroblast growth factor and 20% -50% of epidermal growth factor. Further, the small molecule peptide compound comprises 20-50% of palmitoyl tripeptide, 5-50% of acetyl tetrapeptide and 20-50% of copper peptide. Further, the plant stem cell extract is an extract obtained by plant callus culture, and the plant is at least one of apple, grape or rose. Further, the grease is at least one selected from squalane, caprylic acid/capric acid triglyceride, jojoba oil and polydimethylsiloxane. Further, the surfactant is at least one selected from the group consisting of cetostearyl ether-2, cetostearyl ether-21, tween 20 and tween 80, and the surfactant is at least one selected from the group consisting of cetostearyl ether-2, cetostearyl ether-21, tween 20 and tween 80. Further, the humectant is at least one selected from sodium hyaluronate, glycerol, propylene glycol and trimethylglycine, and the antioxidant is at least one selected from metallothionein, superoxide dismutase, vitamin C and vitamin E. Further, the pH regulator is a citric acid-sodium citrate buffer pair or a lactic acid-sodium lactate buffer pair, and the preservative is at least one selected from methyl benzoate, propyl benzoate and bis (hydroxymethyl) imidazolidinyl urea. The scheme also discloses a preparation method of the cosmetics for resisting aging and accelerating cell metabolism, which mainly comprises the following steps: Heating grease and a surfactant to 75-85 ℃, stirring until the grease and the surfactant are completely dissolved, and cooling to 40-45 ℃ to obtain an oil phase; Dissolving the cell growth factor compound, the small molecule peptide compound, the plant stem cell extract and the antioxidant with deionized water to obtain an active substance aqueous solution; Dissolving a humectant, a pH regulator and a preservative in deionized water to obtain an auxiliary water phase; Adding the active substance aqueous solution into the oil phase, and stirring until the active substance aqueous solution is uniform to obtain a mixed system; And fifthly, adding the auxiliary water phase into the mixed system, and uniformly stirring to obtain a finished product. The beneficial effects obtained by the invention by adopting the structure are as follows: (1) The cell growth factors promote cell proliferation of epidermis and dermis layers, the small molecular peptides regulate cell metabolism and promote collagen synthesis, the plant stem cell extract is rich in polyphenol active ingredients, can activate endogenous stem cell activity of skin, and the three are synergistic through different action paths to obviously promote metabolism rate of skin cells and anti-aging effect. (2) By limiting the proportion relation of the active ingredients and the activity index of the plant stem cell extract, the batch stability and the efficacy reproducibility of the product are ensured. (3)