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CN-121971519-A - A topical Chinese medicinal composition for promoting fracture healing, and its preparation method

CN121971519ACN 121971519 ACN121971519 ACN 121971519ACN-121971519-A

Abstract

The invention belongs to the technical field of external preparations, and provides an external traditional Chinese medicine composition for promoting fracture healing and a preparation method thereof. The external traditional Chinese medicine composition comprises the following components of ground beetle, peach seed, myrrh, angelica, safflower, szechuan lovage rhizome, notopterygium root, frankincense, divaricate saposhnikovia root, tetrahydropalmatine, dahurian angelica root, drynaria rhizome, largetrifoliolious bugbane rhizome, borneol, himalayan teasel root, malaytea scurfpea fruit, twotooth achyranthes root and cassia twig. The formula combines the functions of removing blood stasis (ground beetle and safflower), nourishing blood (Chinese angelica), dispelling wind (notopterygium root and divaricate saposhnikovia root), warming and activating (cassia twig and ginger juice) and transdermal (borneol), and forms the compatibility logic of both attack and repair and internal and external compatibility, thereby removing blood stasis and protecting bones. The composition has the effects of dispelling wind and cold, tonifying kidney and strengthening bones, promoting qi circulation and relieving pain, can treat fracture, and can solve the wind-cold arthralgia, weakness of bones and muscles and intractable distending pain accompanied by fracture, and is especially suitable for fracture patients with joint contracture after fracture and kidney deficiency of middle-aged and elderly people.

Inventors

  • Lu Zizhan
  • LI XIAOYI
  • LI LANTAO

Assignees

  • 衡水市第四人民医院

Dates

Publication Date
20260505
Application Date
20260326

Claims (10)

  1. 1. The external traditional Chinese medicine composition for promoting fracture healing is characterized by comprising, by weight, 12-18 parts of ground beetles, 18-22 parts of peach kernels, 18-22 parts of myrrh, 7-11 parts of angelica sinensis, 20-30 parts of safflower, 18-22 parts of ligusticum wallichii, 7-11 parts of notopterygium roots, 25-35 parts of frankincense, 12-18 parts of radix sileris, 12-18 parts of tetrahydropalmatine, 12-18 parts of radix angelicae, 12-18 parts of rhizoma drynariae, 12-18 parts of cimicifugae foetidae, 3-6 parts of borneol, 12-18 parts of radix dipsaci, 12-18 parts of fructus psoraleae, 12-18 parts of achyranthes bidentata and 12-18 parts of cassia twig.
  2. 2. The external traditional Chinese medicine composition for promoting fracture healing according to claim 1, wherein the external traditional Chinese medicine composition for promoting fracture healing is prepared from the following components, by weight, 15 parts of ground beetles, 20 parts of peach kernels, 20 parts of myrrh, 9 parts of angelica sinensis, 25 parts of safflower, 20 parts of ligusticum wallichii, 9 parts of notopterygium roots, 30 parts of frankincense, 15 parts of radix sileris, 15 parts of tetrahydropalmatine, 15 parts of radix angelicae, 15 parts of rhizoma drynariae, 15 parts of cimicifugae foetidae, 5 parts of borneol, 15 parts of radix dipsaci, 15 parts of fructus psoraleae, 15 parts of achyranthes bidentata and 15 parts of cassia twig.
  3. 3. The external traditional Chinese medicine composition for promoting fracture healing according to claim 1, wherein the external traditional Chinese medicine composition for promoting fracture healing is prepared from the following raw materials, by weight, 12 parts of ground beetles, 22 parts of peach kernels, 18 parts of myrrh, 11 parts of angelica sinensis, 20 parts of safflower, 22 parts of ligusticum wallichii, 7 parts of notopterygium roots, 35 parts of frankincense, 12 parts of radix sileris, 12 parts of tetrahydropalmatine, 18 parts of radix angelicae, 18 parts of rhizoma drynariae, 12 parts of cimicifugae foetidae, 3 parts of borneol, 12 parts of radix dipsaci, 18 parts of fructus psoraleae, 12 parts of achyranthes bidentata and 15 parts of cassia twig.
  4. 4. The external traditional Chinese medicine composition for promoting fracture healing according to claim 1, wherein the external traditional Chinese medicine composition for promoting fracture healing is prepared from the following raw materials, by weight, 15 parts of ground beetles, 22 parts of peach kernels, 20 parts of myrrh, 11 parts of angelica sinensis, 25 parts of safflower, 18 parts of ligusticum wallichii, 11 parts of notopterygium roots, 15 parts of frankincense, 15 parts of radix sileris, 15 parts of tetrahydropalmatine, 15 parts of radix angelicae, 15 parts of rhizoma drynariae, 15 parts of cimicifugae foetidae, 5 parts of borneol, 18 parts of radix dipsaci, 12 parts of fructus psoraleae, 18 parts of achyranthes bidentata and 12 parts of cassia twig.
  5. 5. The external-use Chinese medicinal composition for promoting fracture healing according to claim 1, wherein the external-use Chinese medicinal composition for promoting fracture healing further comprises ginger juice.
  6. 6. The external traditional Chinese medicine composition for promoting fracture healing according to claim 5, wherein the external traditional Chinese medicine composition for promoting fracture healing is prepared from the following raw materials, by weight, 15 parts of ground beetles, 20 parts of peach kernels, 20 parts of myrrh, 9 parts of angelica sinensis, 25 parts of safflower, 20 parts of ligusticum wallichii, 9 parts of notopterygium roots, 30 parts of frankincense, 15 parts of radix sileris, 15 parts of tetrahydropalmatine, 15 parts of radix angelicae, 15 parts of rhizoma drynariae, 15 parts of cimicifugae foetidae, 5 parts of borneol, 15 parts of radix dipsaci, 15 parts of fructus psoraleae, 15 parts of achyranthes bidentata, 15 parts of cassia twig and 72mL of ginger juice.
  7. 7. The method for preparing the external traditional Chinese medicine composition for promoting fracture healing according to any one of claims 1& # x2011 and 6, which is characterized by comprising the following steps: S1, medicinal material treatment Mixing 17 medicinal materials except Borneolum Syntheticum, grinding into fine powder, and sieving; Grinding Borneolum Syntheticum into superfine powder, and mixing with other medicinal materials to obtain medicinal powder; s2, ginger juice preparation Selecting fresh ginger, cleaning, peeling, and cutting into small pieces; Squeezing juice with juicer, or squeezing juice with gauze wrapped with rhizoma Zingiberis recens blocks, filtering to remove rhizoma Zingiberis recens residue, and retaining pure rhizoma Zingiberis recens juice; S3, modulation method Taking materials, weighing the medicinal powder obtained in the step S1 and the ginger juice obtained in the step S2; slowly pouring ginger juice into the medicine powder, and stirring with clean bamboo chopsticks or glass rods while pouring until a thick paste which is not sticky and can be shaped is formed, thus obtaining the external traditional Chinese medicine composition.
  8. 8. The method for preparing a topical Chinese medicinal composition for promoting fracture healing according to claim 7, wherein in the step S1, the sieved particle size is 80 mesh.
  9. 9. The method for preparing a topical Chinese medicinal composition for promoting fracture healing according to claim 7, wherein in the step S3, the ratio of the extracted materials is 20-30mL ginger juice matched with each 100g of medicinal powder.
  10. 10. The application of the external traditional Chinese medicine composition for promoting fracture healing according to any one of claims 1& # x2011 and 6 in preparing medicines for promoting fracture healing.

Description

A topical Chinese medicinal composition for promoting fracture healing, and its preparation method Technical Field The invention belongs to the technical field of external preparations, and relates to an external traditional Chinese medicine composition for promoting fracture healing and a preparation method thereof. Background With the acceleration of the pace of life of people, vehicles are developed gradually and modern building industry develop rapidly, the incidence of fracture is increased continuously, and delayed union and nonunion of fracture are common complications of fracture. How to promote the early healing of fracture and prevent the delayed healing of fracture and the occurrence of fracture nonunion is always a difficult problem of orthopedics. At present, most of the clinical medicines for treating fracture mainly use chemical medicines, but the medicines can generate side effects with different degrees on human bodies, such as inhibition of angiogenesis, ossification and the like, induce hematoma infection, delay healing of fracture after long-term administration, and even bone nonunion. The traditional Chinese medicine considers that fracture healing is subjected to the processes of stasis removal, new generation and ossification, skin swelling at fracture early stage fracture parts, local qi and blood blockage, blood stasis blockage, new blood blockage, and opening of musk spicy fragrance in acanthopanax bark paste, can promote blood stasis in blood, open the stasis in channels and collaterals, has the effects of promoting blood circulation, dredging channels, treating injury and relieving pain, and has the effects of removing stasis Chen Cuo as shown in the cloud of internal channel. After fracture, the bones are injured, the liver governs tendons and kidneys governs bones, cortex acanthopanacis can tonify liver and kidneys and strengthen tendons and bones, and chicken bones and chicken blood are used for raising yang qi to assist callus growth. The Qing dynasty Wu Shiji in the text "li yue" considers that: the external treatment method can dredge the blockage of the channels and collaterals, excite the qi of the channels and collaterals, and combine the efficacy of the medicines to directly reach the disease location, thereby achieving the efficacy of eliminating the diseases. Therefore, research and development of medicaments for treating fracture, which have definite curative effect and small toxic and side effects and are suitable for long-term administration, are urgently needed. Disclosure of Invention In view of the above, the invention provides an external traditional Chinese medicine composition for promoting fracture healing and a preparation method thereof. The invention also provides a preparation method of the external traditional Chinese medicine composition for promoting fracture healing. The invention also provides application of the external traditional Chinese medicine composition for promoting fracture healing in preparing medicines for promoting fracture healing. The technical scheme adopted by the invention for achieving the purpose is as follows: The first aspect of the invention provides an external traditional Chinese medicine composition for promoting fracture healing, which comprises, by weight, 12-18 parts of ground beetle, 18-22 parts of peach kernel, 18-22 parts of myrrh, 7-11 parts of Chinese angelica, 20-30 parts of safflower, 18-22 parts of szechuan lovage rhizome, 7-11 parts of notopterygium root, 25-35 parts of frankincense, 12-18 parts of divaricate saposhnikovia root, 12-18 parts of tetrahydropalmatine, 12-18 parts of dahurian angelica root, 12-18 parts of rhizoma drynariae, 12-18 parts of cimicifugae foetidae, 3-6 parts of borneol, 12-18 parts of himalayan teasel root, 12-18 parts of malaytea scurfpea fruit, 12-18 parts of achyranthes root and 12-18 parts of cassia twig. The invention adopts a preferable technical scheme that the traditional Chinese medicine comprises the following components, by weight, 15 parts of ground beetles, 20 parts of peach kernels, 20 parts of myrrh, 9 parts of angelica sinensis, 25 parts of safflower, 20 parts of ligusticum wallichii, 9 parts of notopterygium roots, 30 parts of frankincense, 15 parts of radix sileris, 15 parts of tetrahydropalmatine, 15 parts of radix angelicae, 15 parts of rhizoma drynariae, 15 parts of rhizoma cimicifugae, 5 parts of borneol, 15 parts of radix dipsaci, 15 parts of fructus psoraleae, 15 parts of achyranthes bidentata and 15 parts of cassia twig. The invention adopts a preferable technical scheme that the traditional Chinese medicine composition comprises, by weight, 12 parts of ground beetles, 22 parts of peach kernels, 18 parts of myrrh, 11 parts of angelica sinensis, 20 parts of safflower, 22 parts of ligusticum wallichii, 7 parts of notopterygium roots, 35 parts of frankincense, 12 parts of radix sileris, 12 parts of tetrahydropalmatine, 18 parts of radix angelicae, 18 parts of rhizoma