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CN-121971522-A - Nerve-soothing sleep-aiding compound for improving sleep quality and application thereof

CN121971522ACN 121971522 ACN121971522 ACN 121971522ACN-121971522-A

Abstract

The invention provides a tranquillizing sleep-aiding compound for improving sleep quality and application thereof. The tranquillizing sleep-aiding compound for improving sleep quality comprises, by weight, 10-30 parts of a spine date seed extract, 5-15 parts of a polygala tenuifolia extract, 2-5 parts of sandalwood, 2-3 parts of bergamot, 2-3 parts of rhizoma corydalis, 1-2 parts of flos albiziae, 1-2 parts of chamomile, 2-3 parts of lavender, 3-5 parts of sweet orange and 8-20 parts of a poria cocos extract. The tranquillizing and sleep aiding compound for improving sleep quality and the application thereof provided by the invention adopt various natural plant extracts and functional components, are safe and free of side effects, can not generate drug dependence and drug resistance after long-term use, are suitable for various sleep disorder people, can obviously shorten sleep time, prolong sleep time, improve sleep depth and effectively improve sleep quality through the synergistic effect of various components, and have good effect of improving sleep disorder caused by stress, anxiety and the like.

Inventors

  • SHI LEI
  • YAN HUI
  • CHEN RUI
  • WANG YUFEI
  • CHEN MENGHUI
  • ZHAO BING

Assignees

  • 中原美谷依莱恩(洛阳)生物科技有限公司

Dates

Publication Date
20260505
Application Date
20260313

Claims (10)

  1. 1. The nerve soothing and sleep aiding compound for improving sleep quality is characterized by comprising the following components in parts by weight: 10-30 parts of semen zizyphi spinosae extract, 5-15 parts of polygala tenuifolia extract, 2-5 parts of sandalwood, 2-3 parts of bergamot, 2-3 parts of rhizoma corydalis, 1-2 parts of flos albiziae, 1-2 parts of chamomile, 2-3 parts of lavender, 3-5 parts of sweet orange, 8-20 parts of poria cocos extract, 6-12 parts of schisandra chinensis extract, 5-15 parts of aminobutyric acid, 3-8 parts of theanine, 4-10 parts of herba melissae extract and 1-3 parts of vitamins.
  2. 2. The tranquillizing sleep aiding compound for improving sleep quality according to claim 1, which is characterized by comprising 23 parts of semen ziziphi spinosae extract, 12 parts of polygala tenuifolia extract, 5 parts of sandalwood, 2 parts of bergamot, 2 parts of rhizoma corydalis, 1 part of flos albiziae, 2 parts of chamomile, 2 parts of lavender, 4 parts of sweet orange, 17 parts of poria cocos extract, 12 parts of shizandra berry extract, 8 parts of aminobutyric acid, 3 parts of theanine, 10 parts of melissa extract and 1 part of vitamin.
  3. 3. The tranquillizing sleep aiding compound for improving sleep quality according to claim 1, wherein the preparation method of the spina date seed extract is characterized in that after the spina date seed extract is crushed, reflux-extracting is carried out for 2-3 times by using 60-80% ethanol solution at 60-80 ℃ for 1-2h each time, and the extract is combined, decompressed and concentrated and dried to obtain the spina date seed extract.
  4. 4. The tranquillizing sleep aiding compound for improving sleep quality according to claim 1, wherein the preparation method of the polygala tenuifolia extract is characterized in that polygala tenuifolia medicinal materials are crushed, 8-12 times of water is added, the mixture is decocted for 2-3 times at 80-100 ℃ for 1-2 hours each time, and the decoction is combined, filtered, concentrated and dried to obtain the polygala tenuifolia extract.
  5. 5. The tranquillizing sleep-aiding compound for improving sleep quality according to claim 1, wherein the poria cocos extract is prepared by pulverizing poria cocos, percolating and extracting the poria cocos with 70-90% ethanol solution at 50-70 ℃, collecting percolate, concentrating under reduced pressure, and drying to obtain the poria cocos extract.
  6. 6. The tranquillizing sleep aiding compound for improving sleep quality according to claim 1, wherein the preparation method of the schisandra chinensis extract is characterized in that schisandra chinensis is extracted for 1-2 times under the ultrasonic power of 300-500W by using 50-70% ethanol solution, the extraction time is 30-60min each time, the extracting solutions are combined, and the schisandra chinensis extract is obtained after decompression concentration and drying.
  7. 7. The tranquillizing sleep aiding compound for improving sleep quality according to claim 1, wherein the preparation method of the melissa extract is characterized in that the melissa extract is obtained by crushing melissa, adding 5-10 times of water, performing ultrasonic extraction for 1-2 times at 60-80 ℃ for 20-40min each time, filtering, concentrating and drying.
  8. 8. The tranquillizing sleep aiding composition for improving sleep quality of claim 1, wherein the vitamin is vitamin B6.
  9. 9. The tranquillizing and sleep aiding composite for improving sleep quality according to claim 1, wherein the preparation method of the tranquillizing and sleep aiding composite for improving sleep quality is used in preparation, and comprises the following steps: S1, weighing the spina date seed extract, the polygala tenuifolia extract, the sandalwood, the bergamot, the rhizoma corydalis, the albizia flower, the chamomile, the lavender, the sweet orange, the poria cocos extract, the schisandra chinensis extract, the theanine and the melissa officinalis extract according to the weight ratio, putting the mixture into a three-dimensional mixer for mixing at the rotating speed of 30r/min for 45-60min, and standing for 10-15min after the mixing is finished; s2, after standing, adding the aminobutyric acid and the vitamin, continuously stirring at the rotating speed of 60r/min for 15-30min to obtain a mixture, And S3, sterilizing and drying the mixture, sieving, magnetically separating, and vacuum packaging to obtain a finished product.
  10. 10. The application of the tranquillizing sleep-aiding compound for improving the sleep quality is characterized in that the compound is used for preparing cosmetics or daily necessities so as to improve the sleep quality, shorten the sleep time and prolong the deep sleep time.

Description

Nerve-soothing sleep-aiding compound for improving sleep quality and application thereof Technical Field The invention relates to the field of sleep-aiding compounds, in particular to a tranquillizing sleep-aiding compound for improving sleep quality and application thereof. Background With the acceleration of modern life pace, working pressure and life pressure of people are continuously increased, and sleep disorder becomes a common health problem. Poor sleep quality for a long period of time not only affects the daily life and work efficiency of people, but also may cause a series of physiological and psychological diseases such as immunity decline, hypomnesis, anxiety, depression, etc. In this context, there is an increasing demand for products capable of improving sleep quality, and the demand direction is gradually shifted from the conventional oral sleep-aiding drugs to safer, milder and more convenient external products. The oral sleep-aiding medicine has the defects of dependence, large side effect, dizziness in the morning and the like, and is difficult to meet the long-term and safe sleep-aiding demands of consumers. The cosmetics and daily necessities are used as products for high frequency use in daily life of people, and by virtue of the characteristics of convenience, mildness and no invasiveness of the use scene, the cosmetics and daily necessities become ideal carriers for carrying the sleep-aiding function, and functional products such as sleep-aiding spray, sleep-aiding emulsion, sleep-aiding aromatherapy, sleep-aiding pillowcase and the like gradually become market hotspots. At present, the existing cosmetics or daily necessities with sleep-aiding function on the market mainly comprise single plant extracts, such as lavender extracts, chamomile extracts, spina date seed extracts and the like, and the core functional components of the cosmetics or daily necessities exert a slight relieving effect through odor volatilization or skin contact. However, the general efficacy components of the product are single, the action mechanism is single, the suitability for different types of sleep disorders is poor, the sleep-aiding effect is limited and the effect is slow, and the requirements of consumers on high-efficiency sleep quality improvement are difficult to meet. Therefore, there is a need to provide a tranquillizing sleep-aiding compound for improving sleep quality and an application thereof to solve the above technical problems. Disclosure of Invention The invention provides a tranquillizing sleep-aiding compound for improving sleep quality and application thereof, and solves the problems in the background technology. In order to solve the technical problems, the tranquillizing sleep-aiding compound for improving sleep quality provided by the invention comprises the following components in parts by weight: 10-30 parts of semen zizyphi spinosae extract, 5-15 parts of polygala tenuifolia extract, 2-5 parts of sandalwood, 2-3 parts of bergamot, 2-3 parts of rhizoma corydalis, 1-2 parts of flos albiziae, 1-2 parts of chamomile, 2-3 parts of lavender, 3-5 parts of sweet orange, 8-20 parts of poria cocos extract, 6-12 parts of schisandra chinensis extract, 5-15 parts of aminobutyric acid, 3-8 parts of theanine, 4-10 parts of herba melissae extract and 1-3 parts of vitamins. Preferably, the Chinese medicinal composition comprises 23 parts of wild jujube seed extract, 12 parts of polygala tenuifolia extract, 5 parts of sandalwood, 2 parts of bergamot, 2 parts of rhizoma corydalis, 1 part of flos albiziae, 2 parts of chamomile, 2 parts of lavender, 4 parts of sweet orange, 17 parts of poria cocos extract, 12 parts of schisandra chinensis extract, 8 parts of aminobutyric acid, 3 parts of theanine, 10 parts of melissa officinalis extract and 1 part of vitamin. Preferably, the preparation method of the semen Ziziphi Spinosae extract comprises pulverizing semen Ziziphi Spinosae, reflux-extracting with 60-80% ethanol solution at 60-80deg.C for 2-3 times, each time for 1-2 hr, mixing extractive solutions, concentrating under reduced pressure, and drying to obtain semen Ziziphi Spinosae extract. Preferably, the preparation method of the polygala tenuifolia extract comprises pulverizing polygala tenuifolia, adding 8-12 times of water, decocting at 80-100deg.C for 2-3 times for 1-2 hr, mixing decoctions, filtering, concentrating, and drying to obtain polygala tenuifolia extract. Preferably, the preparation method of the Poria extract comprises pulverizing Poria, percolating with 70-90% ethanol solution at 50-70deg.C, collecting percolate, concentrating under reduced pressure, and drying to obtain Poria extract. Preferably, the preparation method of the fructus Schisandrae extract comprises extracting fructus Schisandrae with 50-70% ethanol solution under ultrasonic power of 300-500W for 1-2 times for 30-60min each time, mixing extractive solutions, concentrating under reduced pressure, and drying to obtain f