Search

CN-121971570-A - Traditional Chinese medicine composition for treating stomach diseases with different syndromes and preparation method thereof

CN121971570ACN 121971570 ACN121971570 ACN 121971570ACN-121971570-A

Abstract

The invention relates to the technical field of traditional Chinese medicines, and in particular discloses a traditional Chinese medicine composition for treating stomach diseases with different symptoms and a preparation method thereof, wherein the traditional Chinese medicine composition comprises, by weight, 15-25 parts of fried szechwan chinaberry fruit, 8-12 parts of radix bupleuri, 15-35 parts of fried perilla fruit, 40-60 parts of trogopterus dung, 15-35 parts of herba patriniae, 8-12 parts of radix scutellariae, 15-25 parts of radix codonopsis, 30-50 parts of jujube, 15-25 parts of white peony root, 15-25 parts of dried orange peel, 2-6 parts of rheum officinale, 8-12 parts of prepared liquorice and 10-35 parts of hairyvein agrimony, and also comprises 15-35 parts of cuttlebone, 3-5 parts of calcined concha arcae, 40-60 parts of trogopterus dung, 8-12 parts of fried bighead atractylodes rhizome, 15-25 parts of poria cocos, 4-8 parts of pepper, 8-12 parts of fructus amomi, 8-12 parts of cardamomordica, 5-10 parts of fructus evodiae, and four preparations which are respectively accurately aiming at the deficiency of qi, damp and damp, cold and damp, damp and damp, and liver and damp and liver-heat, and cold and stagnation type of the four-syndrome type of the four-type stomach system is formed by the difference and the mutual-cold and the mutual symptoms and the four-stagnation type of the four-stagnation type of the clinical symptoms.

Inventors

  • WU HANJIE

Assignees

  • 山西东方傅山中医药研究院

Dates

Publication Date
20260505
Application Date
20260204

Claims (10)

  1. 1. The traditional Chinese medicine composition for treating stomach diseases with different symptoms is characterized by comprising, by weight, 15-25 parts of fried szechwan chinaberry fruit, 8-12 parts of radix bupleuri, 15-35 parts of fried perilla fruit, 40-60 parts of trogopterus dung, 15-35 parts of herba patriniae, 8-12 parts of radix scutellariae, 15-25 parts of radix codonopsis, 30-50 parts of Chinese date, 15-25 parts of white peony root, 15-25 parts of dried orange peel, 2-6 parts of rheum officinale, 8-12 parts of roasted liquorice, 10-35 parts of hairyvein agrimony, and one or more of 15-35 parts of cuttlebone, 3-5 parts of calcined concha arcae, 40-60 parts of trogopterus dung, 8-12 parts of fried bighead atractylodes rhizome, 15-25 parts of poria cocos, 4-8 parts of pepper, 8-12 parts of fructus amomi, 8-12 parts of cardamom, 5-10 parts of fructus evodiae, 15-25 parts of rudo, 15-25 parts of ruddle, 40-60 parts of semen vaccariae, 10-15 parts of rhizoma sparganii, 10-15 parts of rhizoma zedoariae, 8-12 parts of pseudo-ginseng and 10-15 parts of rhizoma pinellinae.
  2. 2. The traditional Chinese medicine composition for treating stomach diseases with different symptoms according to claim 1, wherein the traditional Chinese medicine composition comprises the following traditional Chinese medicine raw materials, by weight, 15-25 parts of fried szechwan chinaberry fruit, 8-12 parts of radix bupleuri and 15-25 parts of fried perilla fruit; The ministerial drug group comprises 40-60 parts of trogopterus dung, 15-25 parts of herba patriniae, 8-12 parts of radix scutellariae, 15-25 parts of cuttlebone and 1-3 parts of calcined concha arcae; 15-25 parts of codonopsis pilosula, 8-12 parts of stir-fried bighead atractylodes rhizome, 15-25 parts of poria cocos, 30-50 parts of Chinese date, 15-25 parts of white peony root, 4-8 parts of pepper, 15-25 parts of dried orange peel and 2-6 parts of rheum officinale; The Chinese medicinal composition comprises 8-12 parts of honey-fried licorice root and 10-20 parts of hairyvein agrimony.
  3. 3. The traditional Chinese medicine composition for treating stomach diseases with different symptoms according to claim 1, wherein the traditional Chinese medicine composition comprises the following traditional Chinese medicine raw materials, by weight, 15-25 parts of fried szechwan chinaberry fruit, 8-12 parts of radix bupleuri and 15-25 parts of fried perilla fruit; The ministerial drug group comprises 40-60 parts of trogopterus dung, 15-25 parts of herba patriniae, 8-12 parts of radix scutellariae, 15-25 parts of cuttlebone and 1-3 parts of calcined concha arcae; 15-25 parts of codonopsis pilosula, 8-12 parts of fructus amomi, 8-12 parts of cardamom, 30-50 parts of jujube, 15-25 parts of white paeony root, 4-8 parts of pepper, 15-25 parts of dried orange peel and 2-6 parts of rheum officinale; The Chinese medicinal composition comprises 8-12 parts of honey-fried licorice root and 10-20 parts of hairyvein agrimony.
  4. 4. The traditional Chinese medicine composition for treating stomach diseases with different symptoms according to claim 1, wherein the traditional Chinese medicine composition comprises the following traditional Chinese medicine raw materials in parts by weight, and is characterized in that the monarch drug group comprises 25-35 parts of stir-fried perilla fruit and 5-10 parts of evodia rutaecarpa; the ministerial drug group comprises 8-12 parts of bupleurum, 15-25 parts of fried chinaberry fruit, 25-35 parts of cuttlebone, 3-5 parts of calcined concha arcae and 15-25 parts of ruddle; 15-25 parts of codonopsis pilosula, 8-12 parts of stir-fried bighead atractylodes rhizome, 15-25 parts of poria cocos, 30-50 parts of Chinese date, 15-25 parts of white paeony root, 4-8 parts of pepper, 15-25 parts of dried orange peel, 2-6 parts of rheum officinale, 15-25 parts of herba patriniae and 8-12 parts of radix scutellariae; The Chinese medicinal composition comprises 8-12 parts of honey-fried licorice root and 10-20 parts of hairyvein agrimony.
  5. 5. The traditional Chinese medicine composition for treating stomach diseases with different symptoms according to claim 1, wherein the traditional Chinese medicine composition comprises the following traditional Chinese medicine raw materials in parts by weight, namely 40-60 parts of semen vaccariae, 10-15 parts of rhizoma sparganii and 10-15 parts of rhizoma curcumae; the ministerial drug group comprises 8-12 parts of bupleurum, 15-25 parts of fried szechwan chinaberry fruit, 15-25 parts of fried perilla fruit, 8-12 parts of pseudo-ginseng and 10-15 parts of rhizoma pinellinae praeparata; 15-25 parts of codonopsis pilosula, 8-12 parts of stir-fried bighead atractylodes rhizome, 15-25 parts of poria cocos, 30-50 parts of Chinese date, 15-25 parts of white paeony root, 15-25 parts of dried orange peel, 2-6 parts of rheum officinale, 25-35 parts of herba patriniae and 8-12 parts of radix scutellariae; The Chinese medicinal composition comprises herba et Gemma Agrimoniae 25-35 parts and radix Glycyrrhizae Preparata 8-12 parts.
  6. 6. The method for preparing the traditional Chinese medicine composition for treating stomach diseases with different symptoms according to claim 2, which is characterized by comprising the following steps: Pulverizing Atractylodis rhizoma and Poria to 10-20 mesh, adding water at a feed-liquid ratio of 1:8, soaking at 200-300MPa under normal temperature and ultrahigh pressure for 30 min; blowing and boiling at 80-90deg.C and 0.1-0.2MPa for 40 min, re-boiling the residue for 30min, and mixing decoctions; Concentrating under reduced pressure at 60deg.C to relative density of 1.15-1.20, and spray drying at air inlet of 180-200deg.C, air outlet of 80-90deg.C and atomization pressure of 0.3-0.4 MPa; 10% dextrin was added and dry granulated at a pressure of 5-7 kgf.
  7. 7. The method for preparing the traditional Chinese medicine composition for treating stomach diseases with different symptoms according to claim 3, which is characterized by comprising the following steps: Superfine pulverizing fructus Amomi and fructus Amomi rotundus to particle size less than 75 μm, adding water into the rest materials at a feed-liquid ratio of 1:10, and soaking at 200-300MPa under normal temperature and superhigh pressure for 30 min; blowing and boiling for 40 min at 70-80deg.C and 0.1MPa, filtering, concentrating, and spray drying at 160-170deg.C and 70-80deg.C; mixing the volatile oil micropowder with the extract powder at a ratio of 1:5, adding 5% PVP-k30 ethanol solution, and granulating.
  8. 8. The method for preparing the traditional Chinese medicine composition for treating stomach diseases with different symptoms according to claim 4, which is characterized by comprising the following steps: pulverizing fructus evodiae at-5deg.C to 20 mesh, pulverizing Haematitum into superfine powder, adding water according to a feed-liquid ratio of 1:9, extracting at 250MPa and 60 deg.C under ultrahigh pressure for 40 min, and filtering with 0.2 μm ceramic membrane; double-effect concentration at 55 ℃ to a relative density of 1.18, and freeze drying at-40 ℃ for 24 hours; 8% pregelatinized starch was added and wet granulated with 45% ethanol.
  9. 9. The method for preparing the traditional Chinese medicine composition for treating stomach diseases with different symptoms according to claim 5, which is characterized by comprising the following steps: pulverizing semen Vaccariae and Notoginseng radix to 20-30 mesh at-10deg.C, and pulverizing the rest materials to 10-15 mesh; Adding water according to a feed-liquid ratio of 1:12, soaking for 40 minutes under the condition of 250-350MPa, and then blowing and boiling for 50 minutes under the conditions of 60-70 ℃ and 0.08-0.12MPa under reduced pressure; Adding 70% ethanol into the residue, performing ultrasonic extraction at 300W power for 30 min at a feed-liquid ratio of 1:6, and mixing the extractive solutions; Concentrating under reduced pressure at 55deg.C to relative density of 1.20-1.25, and vacuum drying at 60deg.C-0.09 MPa; adding 8% beta-cyclodextrin, wet granulating with 50% ethanol, and oven drying at 60deg.C.
  10. 10. The application of the traditional Chinese medicine composition according to any one of claims 1-5 in preparing medicines for treating corresponding type stomach diseases, wherein the application comprises the preparation of medicines for treating stomach diseases with qi deficiency of spleen and stomach and water dampness, medicines for treating stomach diseases with cold-dampness qi stagnation and cold-heat mixed type, medicines for treating liver-stomach disharmony and cold-heat mixed type reflux diseases and medicines for treating phlegm-blood stasis combined type stomach polyps.

Description

Traditional Chinese medicine composition for treating stomach diseases with different syndromes and preparation method thereof Technical Field The invention belongs to the technical field of traditional Chinese medicines, and in particular relates to a traditional Chinese medicine composition for treating stomach diseases with different symptoms and a preparation method thereof. Background At present, western medicine adopts therapies composed of proton pump inhibitors, antibacterial drugs and the like in the treatment of gastric diseases, but has the problems of increased drug resistance, high recurrence rate, insufficient overall regulation capacity and the like, and has limited long-term regulation effects on complex and chronic persistent gastric diseases. For example, aiming at the symptoms of qi deficiency of spleen and stomach and water dampness, the traditional decoction technology is generally adopted in the existing prescription for strengthening spleen and excreting dampness, so that the dissolution rate of active ingredients is less than 60%, wherein the loss of polysaccharide active ingredients is 35%, and the problems of excessive dosage, long period of relieving internal water dampness stopping symptoms and the like are caused, so that the core symptoms of patients are difficult to improve quickly. Aiming at cold-dampness stagnation and cold-heat disharmony syndrome, the existing preparation has key defects of cold-heat regulation imbalance, lacks specific aromatic dampness resolving components, has poor effect of improving dampness resistance characteristics, has single action mechanism aiming at liver-stomach disharmony type reflux diseases, has extremely low inhibition rate on polyps, and cannot meet clinical treatment and recurrence prevention requirements Disclosure of Invention The invention aims to provide a traditional Chinese medicine composition for treating stomach diseases with different symptoms and a preparation method thereof, and aims to solve the problems that the existing preparation provided in the background art is single in action mechanism and poor in core symptom improvement effect. In order to achieve the above purpose, the present invention provides the following technical solutions: The traditional Chinese medicine composition for treating stomach diseases with different symptoms comprises, by weight, 15-25 parts of fried szechwan chinaberry fruit, 8-12 parts of radix bupleuri, 15-35 parts of fried perilla fruit, 40-60 parts of trogopterus dung, 15-35 parts of herba patriniae, 8-12 parts of radix scutellariae, 15-25 parts of radix codonopsis pilosulae, 30-50 parts of jujube, 15-25 parts of radix paeoniae alba, 15-25 parts of dried orange peel, 2-6 parts of rheum officinale, 8-12 parts of honey-fried licorice root, 10-35 parts of hairyvein agrimony, and one or more of 15-35 parts of cuttlebone, 3-5 parts of calcined concha arcae, 40-60 parts of trogopterus dung, 8-12 parts of fried bighead atractylodes rhizome, 15-25 parts of poria cocos, 4-8 parts of pepper, 8-12 parts of fructus amomi, 8-12 parts of cardamon, 5-10 parts of fructus evodiae, 15-25 parts of ruddle, 40-60 parts of semen vaccariae, 10-15 parts of rhizoma spargani, 8-12 parts of rhizoma zedoariae, 10-15 parts of pseudo-ginseng and 10-15 parts of rhizoma pinelliae. Preferably, the traditional Chinese medicine composition comprises the following traditional Chinese medicine raw materials, by weight, 15-25 parts of fried szechwan chinaberry fruit, 8-12 parts of radix bupleuri and 15-25 parts of fried perilla fruit; The ministerial drug group comprises 40-60 parts of trogopterus dung, 15-25 parts of herba patriniae, 8-12 parts of radix scutellariae, 15-25 parts of cuttlebone and 1-3 parts of calcined concha arcae; 15-25 parts of codonopsis pilosula, 8-12 parts of stir-fried bighead atractylodes rhizome, 15-25 parts of poria cocos, 30-50 parts of Chinese date, 15-25 parts of white peony root, 4-8 parts of pepper, 15-25 parts of dried orange peel and 2-6 parts of rheum officinale; The Chinese medicinal composition comprises 8-12 parts of honey-fried licorice root and 10-20 parts of hairyvein agrimony. Preferably, the traditional Chinese medicine composition comprises the following traditional Chinese medicine raw materials, by weight, 15-25 parts of fried szechwan chinaberry fruit, 8-12 parts of radix bupleuri and 15-25 parts of fried perilla fruit; The ministerial drug group comprises 40-60 parts of trogopterus dung, 15-25 parts of herba patriniae, 8-12 parts of radix scutellariae, 15-25 parts of cuttlebone and 1-3 parts of calcined concha arcae; 15-25 parts of codonopsis pilosula, 8-12 parts of fructus amomi, 8-12 parts of cardamom, 30-50 parts of jujube, 15-25 parts of white paeony root, 4-8 parts of pepper, 15-25 parts of dried orange peel and 2-6 parts of rheum officinale; The Chinese medicinal composition comprises 8-12 parts of honey-fried licorice root and 10-20 parts of hairyvein agrimony. Preferably,