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CN-121971582-A - Traditional Chinese medicine composition and pharmaceutical preparation for treating chronic obstructive pneumonia

CN121971582ACN 121971582 ACN121971582 ACN 121971582ACN-121971582-A

Abstract

The invention relates to the technical field of traditional Chinese medicine preparations, in particular to a traditional Chinese medicine composition and a pharmaceutical preparation for treating chronic obstructive pneumonia. The Chinese medicinal composition comprises blackberry lily, roasted ephedra herb, dried ginger, asarum, aster, coltsfoot flower, citrus red, shizandra berry, fried radish seed, perilla, white mustard seed and liquorice. The traditional Chinese medicine composition and the pharmaceutical preparation provided by the invention are used for patients with chronic obstructive pneumonia, can recover the lung ventilation function, effectively inhibit inflammatory reaction in vivo, promote lung tissue injury repair, and have a better treatment effect on chronic obstructive pneumonia.

Inventors

  • CHEN XIANGLI

Assignees

  • 北京兰德万邦医药科技有限公司

Dates

Publication Date
20260505
Application Date
20260401

Claims (10)

  1. 1. A traditional Chinese medicine composition for treating chronic obstructive pneumonia is characterized by comprising blackberry lily, roasted ephedra herb, dried ginger, asarum, aster honey, coltsfoot flower honey, citrus aurantium, schisandra chinensis, fried radish seed, perilla seed, white mustard seed and liquorice.
  2. 2. The traditional Chinese medicine composition according to claim 1, wherein the traditional Chinese medicine composition comprises the following components in parts by weight: 70-110 parts of blackberry lily, 80-120 parts of roasted ephedra, 40-80 parts of dried ginger, 10-50 parts of asarum, 80-120 parts of aster melitensis, 80-120 parts of honey coltsfoot flower, 100-140 parts of citrus aurantium, 80-120 parts of schisandra chinensis, 130-170 parts of roasted radish seed, 130-170 parts of perilla fruit, 80-120 parts of white mustard seed and 40-80 parts of liquorice.
  3. 3. The traditional Chinese medicine composition according to claim 2, wherein the traditional Chinese medicine composition comprises the following components in parts by weight: 80-100 parts of blackberry lily, 90-110 parts of roasted ephedra, 50-70 parts of dried ginger, 20-40 parts of asarum, 90-110 parts of aster, 90-110 parts of honey coltsfoot flower, 110-130 parts of citrus aurantium, 90-110 parts of schisandra chinensis, 140-160 parts of roasted radish seed, 140-160 parts of perilla fruit, 90-110 parts of white mustard seed and 50-70 parts of liquorice.
  4. 4. The traditional Chinese medicine composition according to claim 3, wherein the traditional Chinese medicine composition comprises the following components in parts by weight: 90 parts of blackberry lily, 100 parts of roasted ephedra herb, 60 parts of dried ginger, 30 parts of asarum, 100 parts of aster, 100 parts of honey coltsfoot flower, 120 parts of dried orange peel, 100 parts of shizandra berry, 150 parts of fried radish seed, 150 parts of perilla seed, 100 parts of white mustard seed and 60 parts of liquorice.
  5. 5. The use of a Chinese medicinal composition according to any one of claims 1-4 in the manufacture of a medicament for the treatment of chronic obstructive pulmonary disease.
  6. 6. A pharmaceutical preparation for treating chronic obstructive pneumonia, characterized in that it comprises an active ingredient of the traditional Chinese medicine composition according to any one of claims 1-4.
  7. 7. The pharmaceutical formulation of claim 6, wherein the pharmaceutical formulation is in the form of a tablet, capsule, granule, oral liquid, or syrup.
  8. 8. A method of preparing a pharmaceutical formulation according to claim 6 or 7, comprising the steps of: (1) Extracting the medicinal materials with water to obtain water extract; (2) Preparing the aqueous extract into a dosage form of the pharmaceutical preparation.
  9. 9. The preparation method of claim 8, wherein the water extraction method comprises decocting for at least 2 times, each time 1-3 h, filtering to obtain water extract; And/or the mass of the water in the water extraction is 10-30 times of the total mass of the medicinal materials.
  10. 10. The method according to claim 8 or 9, wherein the step (2) comprises vacuum concentrating the aqueous extract to obtain the pharmaceutical preparation.

Description

Traditional Chinese medicine composition and pharmaceutical preparation for treating chronic obstructive pneumonia Technical Field The invention relates to the technical field of traditional Chinese medicine preparations, in particular to a traditional Chinese medicine composition and a pharmaceutical preparation for treating chronic obstructive pneumonia. Background Chronic obstructive pulmonary disease (Chronic Obstructive Pulmonary Disease, COPD, simply slow obstructive pulmonary) is a disease state characterized by an incompletely reversible airflow limitation that is a recurrent, progressive progression associated with abnormal inflammatory responses of the lungs to noxious gases or noxious particles. COPD is characterized by persistent low-grade lung inflammation and airflow obstruction, although treatment for Chronic Obstructive Pulmonary Disease (COPD) has improved over the past two decades, modern medicine has been largely classified into non-drug therapies such as oxygen therapy, smoking cessation, etc., drug therapies are mainly promotion of bronchodilators, antibacterial agents, hormonal agents, etc., effects are not ideal, and with long-term use of antibiotics, hormones, etc., therapeutic effects have been reduced. Therefore, it is necessary to supplement the traditional Chinese medicine preparation. The traditional Chinese medicine is named as lung distension, exogenous wind-cold and wind-heat are important factors for inducing the acute attack of the disease, and exogenous wind-heat and pathogenic wind-dryness can cause the lung to lose dispersing and descending, and phlegm-heat is accumulated in the lung to cause the disease. The pathogenesis is that qi stagnation, phlegm obstruction and airway obstruction and phlegm stasis are combined, which are the symptoms of the deficiency and the excess of the principal and secondary aspects of the disease, and the symptoms of the acute attack are the symptoms of phlegm heat accumulated in the lung. The traditional Chinese medicine has abundant experience accumulation in the aspect of pulmonary disease treatment, and has important scientific significance in exploring the therapeutic drugs of COPD in the classical prescription of traditional Chinese medicine and ethnic medicine. Disclosure of Invention In order to solve the technical problems, the invention provides a traditional Chinese medicine composition and a pharmaceutical preparation for treating chronic obstructive pneumonia, which are used for patients with chronic obstructive pneumonia, can recover the lung ventilation function, effectively inhibit inflammatory reaction in vivo, promote repair of lung tissue injury, and have better treatment effect on chronic obstructive pneumonia. In a first aspect, the invention provides a traditional Chinese medicine composition for treating chronic obstructive pneumonia, which comprises blackberry lily, roasted ephedra, dried ginger, asarum, aster, coltsfoot flower, citrus peel, shizandra berry, fried radish seed, perilla, white mustard seed and liquorice. The traditional Chinese medicine composition provided by the invention is used for patients with chronic obstructive pneumonia, can recover the lung ventilation function, effectively inhibit inflammatory reaction in vivo, promote lung tissue injury repair, and has a better treatment effect on chronic obstructive pneumonia. As a preferable technical scheme of the invention, the traditional Chinese medicine composition comprises the following components in parts by weight: 70-110 parts of blackberry lily, 80-120 parts of roasted ephedra, 40-80 parts of dried ginger, 10-50 parts of asarum, 80-120 parts of aster melitensis, 80-120 parts of honey coltsfoot flower, 100-140 parts of citrus aurantium, 80-120 parts of schisandra chinensis, 130-170 parts of roasted radish seed, 130-170 parts of perilla fruit, 80-120 parts of white mustard seed and 40-80 parts of liquorice. Wherein, the blackberry lily can be 70 weight parts, 80 weight parts, 90 weight parts, 100 weight parts, 110 weight parts and the like. The herba Ephedrae may be 80 parts by weight, 90 parts by weight, 100 parts by weight, 110 parts by weight, 120 parts by weight, etc. The dried ginger may be 40 parts by weight, 50 parts by weight, 60 parts by weight, 70 parts by weight, 80 parts by weight, etc. The asarum may be 10 parts by weight, 20 parts by weight, 30 parts by weight, 40 parts by weight, 50 parts by weight, etc. The aster melittifolius may be 80 parts by weight, 90 parts by weight, 100 parts by weight, 110 parts by weight, 120 parts by weight, etc. The honey coltsfoot flower may be 80 parts by weight, 90 parts by weight, 100 parts by weight, 110 parts by weight, 120 parts by weight, etc. The citrus red may be 100 parts by weight, 110 parts by weight, 120 parts by weight, 130 parts by weight, 140 parts by weight, etc. The schisandra chinensis may be 80 parts by weight, 90 parts by weight, 100 parts by weight, 110 parts by weight, 120 parts by