CN-121971604-A - Hemostatic and antibacterial kaolin/molybdenum sulfide photo-thermal composite material and preparation method and application thereof

Abstract

The invention relates to the technical field of photo-thermal composite materials, in particular to a hemostatic and antibacterial kaolin/molybdenum sulfide photo-thermal composite material, and a preparation method and application thereof. A hemostatic and antibacterial composite material of kaolin and molybdenum sulfide comprises kaolin and metal 1T phase MoS 2 loaded on the kaolin. The preparation method comprises the steps of dissolving a molybdenum source and a sulfur source in deionized water, adding kaolin for hydrothermal reaction, centrifuging, washing and drying to obtain the hemostatic and antibacterial kaolin/molybdenum sulfide photo-thermal composite material. According to the invention, the kaolin with a layered structure and surface charge characteristics is introduced, so that molybdenum sulfide grows in situ between layers or on the surface of a kaolin body, controllable transformation of molybdenum sulfide from 2H to 1T is realized, and the 1T molybdenum sulfide can exist stably, so that the composite material with high photo-thermal performance and temperature balance capability is obtained. The molybdenum sulfide is loaded on the kaolin, so that the hemostatic performance of the kaolin is further improved.

Inventors

• YANG HUAMING
• TAN YA
• WANG HAO

Assignees

• 中国地质大学（武汉）

Dates

Publication Date

20260505

Application Date

20251212

Claims (9)

1. 1. A hemostatic and antibacterial kaolin/molybdenum sulfide photo-thermal composite material, which is characterized by comprising kaolin and metal 1T phase MoS 2 loaded on the kaolin.
2. 2. A method for preparing the hemostatic and antibacterial kaolin/molybdenum sulfide photo-thermal composite material according to claim 1, wherein a molybdenum source and a sulfur source are dissolved in deionized water, and after the hydrothermal reaction of kaolin is added, the hemostatic and antibacterial kaolin/molybdenum sulfide photo-thermal composite material is obtained through centrifugation, washing and drying.
3. 3. The method according to claim 2, wherein the molar ratio of the molybdenum element to the sulfur element in the molybdenum source and the sulfur source is 8 to 3:1.
4. 4. The method of claim 2, wherein the molybdenum source has a molar mass ratio of elemental molybdenum to kaolin of 0.0398mol:1g.
5. 5. The process according to claim 2, wherein the hydrothermal reaction is carried out at a temperature of 180-220 ℃ for a time of 20-26 hours.
6. 6. The method of claim 2, wherein the drying temperature is 60 ℃ to 80 ℃.
7. 7. The method of claim 2, wherein the molybdenum source is NaMoO 4 ·2H 2 O.
8. 8. The method of claim 2, wherein the sulfur source is SC (NH 2 ) 2 .
9. 9. The application of the hemostatic and antibacterial kaolin/molybdenum sulfide photo-thermal composite material is characterized by being used as a photo-thermal reagent or a hemostatic and antibacterial agent.

Description

Hemostatic and antibacterial kaolin/molybdenum sulfide photo-thermal composite material and preparation method and application thereof Technical Field The invention relates to the technical field of photo-thermal composite materials, in particular to a hemostatic and antibacterial kaolin/molybdenum sulfide photo-thermal composite material, and a preparation method and application thereof. Background At present, bacterial infection and inflammation seriously hinder wound healing, possibly leading to serious tissue damage, highlighting the urgent need for innovative therapeutic strategies. Phototherapy (PTT) uses photothermal conversion agents to convert light into localized heat, effectively eliminating pathogens and promoting tissue repair. Studies have shown that bacterial protein denaturation can be induced when wound temperature reaches 50 ℃, and that temperatures exceeding 60 ℃ can cause thermal tissue damage, leading to rapid protein denaturation and cell membrane rupture, ultimately leading to immediate cell death. Traditional photothermal agents, such as manganese quantum dots, pdH and CuS-MXene, often undergo thermal runaway under near infrared irradiation, with local temperatures up to 68.9 ℃, exacerbating tissue damage. This situation highlights a fundamental design bottleneck, gao Guangre, an inherent tradeoff between conversion efficiency (PCE) and thermal starvation. Therefore, an ideal photothermal agent must integrate a high PCE (realized by a narrow bandgap and efficient non-radiative relaxation) with excellent thermal conductivity. However, current research mainly emphasizes lifting PCEs, while ignoring nanoscale thermal regulation. Achieving PCE elevation while maintaining temperature within a safe range is a critical challenge in the PTT field for breakthrough. Molybdenum sulfide (MoS 2) is a typical layered transition metal sulfide material, has excellent multi-physical field coupling characteristics of light, electricity, heat and the like, and has been widely used in the fields of photo-thermal conversion, photocatalysis and biomedicine in recent years. The MoS 2 crystals have mainly two common phase structures, namely a hexagonal 2H phase and a tetragonal 1T phase. The 2H phase has higher thermodynamic stability and shows semiconductor characteristics, while the 1T phase has metallic and higher carrier density, and can remarkably improve light absorption efficiency and light-heat conversion performance. Related researches show that the photo-thermal conversion efficiency of the 1T-MoS 2 is obviously higher than that of the 2H-MoS 2, and the photo-thermal conversion efficiency can show excellent performances in the fields of photo-thermal treatment, antibiosis, energy conversion and the like. However, the 1T phase structure is in a metastable state and is extremely susceptible to spontaneous conversion to a 2H phase under light, heat treatment or air exposure conditions, resulting in reduced material properties. The prior researches generally adopt methods such as chemical intercalation, plasma treatment or heterostructure compounding to regulate and control the phase change behavior of MoS 2. The chemical intercalation method induces electron injection by introducing lithium ions or sodium ions into the interlayer of the MoS 2 to achieve 2H to 1T phase transition. For example, a high proportion of 1T-MoS 2 can be obtained by using n-butyllithium intercalation, but the method has the advantages of harsh reaction conditions, complex process, high requirements on environment and safety and poor stability of the obtained material in air, and needs to use a strong reducing agent. The plasma treatment method and the high-energy beam irradiation method can realize the regulation and control of the surface layer phase structure, but expensive equipment and high-energy input are required, only a limited phase change area can be generated on the surface of the material, and uniform and controllable structure regulation is difficult to realize. The stress induction method and the interface heterogeneous compound method regulate interlayer slippage by constructing different substrates or strain fields to influence the MoS 2 phase structure, but the requirements on interface matching and stress directions are strict, and the process repeatability is poor. In addition, heterostructure recombination such as combination with oxide or graphene can stabilize the 1T phase to a certain extent, but the preparation process is complex, and the interface electronic coupling is difficult to control accurately. The prior art has the problems of complex process, harsh reaction conditions, high energy consumption, poor environmental compatibility and the like. In addition, the prior modified MoS 2 composite material has the problems of poor temperature regulation performance and unstable photothermal treatment temperature. In conclusion, the existing molybdenum sulfide phase change regulation and control method