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CN-121971679-A - Antibacterial dressing composition and medical gynecological protection pad

CN121971679ACN 121971679 ACN121971679 ACN 121971679ACN-121971679-A

Abstract

The invention provides an antibacterial dressing composition and a medical gynecological protection pad, and belongs to the technical field of medical dressings. The composition comprises 70-90 parts of water, 8-10 parts of polyethylene glycol, 4-6 parts of glycerin, 0.3-0.7 part of carbomer, 0.06-0.15 part of L-cysteine, 4-8 parts of chitosan quaternary ammonium salt, 0.3-0.8 part of panthenol, 0.4-0.7 part of tocopheryl acetate, 0.2-0.4 part of sodium hyaluronate, 0.1-0.3 part of chlorhexidine digluconate, 3-4 parts of polyvinylpyrrolidone, 1-5 parts of sodium alginate, 0.1-0.3 part of polysorbate, 0.6-0.9 part of luteolin, 0.1-0.2 part of quercetin and 0.05-0.2 part of matrine. The invention takes chitosan quaternary ammonium salt and chlorhexidine digluconate as sterilization components, and adds quercetin and matrine as bacteriostat, and forms a dispersion system with active components such as panthenol, tocopheryl acetate, luteolin and the like and film forming agent. The invention not only has remarkable antibacterial property, but also has the effects of anti-inflammatory, moisturizing, tissue repair promotion and the like. The gynecological protection pad is used for acting on the inflammation surface of the vulva, so that the exact treatment effect can be realized.

Inventors

  • NIU QINGHAI
  • NIU HAO
  • NIU LEI
  • LIU ZHAOFANG

Assignees

  • 临沂康利医疗器械有限公司

Dates

Publication Date
20260505
Application Date
20260128

Claims (10)

  1. 1. The antibacterial dressing composition is characterized by comprising, by weight, 70-90 parts of water, 8-10 parts of polyethylene glycol, 4-6 parts of glycerin, 0.3-0.7 part of carbomer, 0.06-0.15 part of L-cysteine, 4-8 parts of chitosan quaternary ammonium salt, 0.3-0.8 part of panthenol, 0.4-0.7 part of tocopheryl acetate, 0.2-0.4 part of sodium hyaluronate, 0.1-0.3 part of chlorhexidine digluconate, 3-4 parts of polyvinylpyrrolidone, 1-5 parts of sodium alginate, 0.1-0.3 part of polysorbate, 0.6-0.9 part of luteolin, ‌ 0.1.1-0.2 part of quercetin and 0.05-0.2 part of matrine.
  2. 2. The antimicrobial dressing composition according to claim 1, further comprising 0.8 to 1.7 parts by weight of xanthan gum.
  3. 3. The antimicrobial dressing composition according to claim 1, further comprising 0.03 to 0.08 parts by weight of epidermal growth factor EGF.
  4. 4. The antimicrobial dressing composition according to claim 1, further comprising 0.06 to 0.15 parts by weight of silk fibroin.
  5. 5. The antimicrobial dressing composition according to claim 1, further comprising 0.5 to 0.8 parts by weight of baicalin.
  6. 6. The antibacterial dressing composition according to claim 1, wherein the antibacterial dressing composition comprises, by weight, 75-85 parts of water, 8.8-9.4 parts of polyethylene glycol, 4.5-5 parts of glycerin, 0.4-0.6 part of carbomer, 0.08-0.12 part of L-cysteine, 5-7 parts of chitosan quaternary ammonium salt, 0.4-0.6 part of panthenol, 0.5-0.65 part of tocopheryl acetate, 0.26-0.33 part of sodium hyaluronate, 0.25-0.3 part of chlorhexidine digluconate, 3.4-3.7 parts of polyvinylpyrrolidone, 2.2-3.9 parts of sodium alginate, 0.15-0.24 part of polysorbate, 0.8-0.85 part of luteolin, ‌ 0.12.12-0.16 part of quercetin and 0.13-0.17 part of matrine.
  7. 7. The antibacterial dressing composition according to claim 6, which comprises the following components, by weight, 80 parts of water, 9.1 parts of polyethylene glycol, 4.8 parts of glycerin, 0.53 part of carbomer, 0.11 part of L-cysteine, 6.2 parts of chitosan quaternary ammonium salt, 0.55 part of panthenol, 0.62 part of tocopheryl acetate, 0.31 part of sodium hyaluronate, 0.29 part of chlorhexidine digluconate, 3.6 parts of polyvinylpyrrolidone, 3.4 parts of sodium alginate, 0.2 part of polysorbate, 0.82 part of luteolin, ‌ 0.15.15 parts of quercetin and 0.17 part of matrine.
  8. 8. The antibacterial dressing composition according to claim 6, which comprises the following components, by weight, 80 parts of water, 9.1 parts of polyethylene glycol, 4.8 parts of glycerin, 0.53 part of carbomer, 0.11 part of L-cysteine, 6.2 parts of chitosan quaternary ammonium salt, 0.55 part of panthenol, 0.62 part of tocopheryl acetate, 0.31 part of sodium hyaluronate, 0.29 part of chlorhexidine digluconate, 3.6 parts of polyvinylpyrrolidone, 3.4 parts of sodium alginate, 0.2 part of polysorbate, 0.82 part of luteolin, 0.15 part of quercetin ‌, 0.17 part of matrine, 1.1 part of xanthan gum, 0.06 part of epidermal growth factor EGF, 0.13 part of silk fibroin and 0.52 part of baicalin.
  9. 9. A medical gynecological pad comprising the antibacterial dressing composition according to any one of claims 1 to 8.
  10. 10. The medical gynecological pad according to claim 9, wherein the antibacterial dressing composition is sprayed on the contact surface of the medical gynecological pad with the human body.

Description

Antibacterial dressing composition and medical gynecological protection pad Technical Field The invention relates to the technical field of medical dressing, in particular to an antibacterial dressing composition and a medical gynecological protection pad. Background Medical dressings are specialized materials used in the medical field to cover wounds or damaged skin, with primary functions including isolating external contamination, absorbing exudates, maintaining a moist environment of the wound, promoting healing, and reducing the risk of infection. The medical device is divided into traditional type (such as gauze and cotton pad) and functional type (such as hydrocolloid and foam dressing) according to materials and purposes, and is widely applied to the scenes of postoperative care, burn, chronic ulcer and the like. For wound surfaces and mucous membranes, the dressing not only serves as a physical barrier, but also plays roles in absorbing and moisturizing, and meanwhile, part of functional dressing also has the effects of relieving pain, assisting treatment and the like. The dressing can prevent bacteria, dust and other pollutants from contacting the wound surface, thereby reducing the incidence rate of infection, balancing the absorption of exudates and the humidity of the wound surface, avoiding excessive dryness or effusion and accelerating cell migration, part of the dressing contains gel or adhesive layer, can reduce tearing damage to new tissue during dressing change, and part of the dressing (such as silver ion and chitosan) has the functions of resisting bacteria, diminishing inflammation or promoting angiogenesis. ‌ Gynecological dressing ‌ is a medical material for ‌ female vulva, vagina or postoperative wound care ‌, has the main functions of ‌ promoting healing, reducing infection and relieving discomfort ‌, and is suitable for postoperative recovery, inflammation care or daily cleaning maintenance. The liquid dressing mainly comprises a liquid dressing, a gel dressing, a foam dressing and the like, wherein the liquid dressing is mostly spray or rinse, contains chitosan, hyaluronic acid and other components, forms a protective film and is used for relieving red swelling, the foam dressing has high absorptivity and is mostly used for the condition of more postoperative seepage, and the gel dressing is suitable for dry or slightly damaged skin, provides a moist environment and relieves itching. Vulvitis is an inflammatory reaction of the skin and mucous membrane of the female vulva, and common symptoms include itching, redness, pain or abnormal secretions. Vulvitis is mostly caused by microbial infection, wherein bacteria (such as streptococcus and staphylococcus), fungi (such as candida) and viruses (such as HPV) are main pathogens, and especially female vagina is communicated with the outside, and the infection is easily caused by unbalanced flora or improper sanitation. In the prior art, the treatment of the external inflammation still mainly depends on medicines, such as external miconazole nitrate for fungal infection, oral fluconazole, oral metronidazole for bacterial infection and other antibiotics. Although the functional gynecological dressing has certain antibacterial property, the antibacterial efficacy is weak, the purpose of curing the vulvitis is not achieved, and the administration mode is inconvenient, so that the application of the liquid dressing in the treatment of gynecological diseases is affected to a certain extent. Disclosure of Invention Aiming at the technical defects of the prior art, the invention provides an antibacterial dressing composition for solving the technical problem that the conventional gynecological dressing has weaker antibacterial property. Another technical problem to be solved by the present invention is how to develop an antimicrobial dressing composition with an exact therapeutic effect on vulvitis. Meanwhile, the invention provides a medical gynecological protection pad containing the antibacterial dressing composition, so as to solve the technical problem of inconvenient administration of the liquid dressing when the liquid dressing is applied to the vulva part. In order to achieve the technical purpose, the invention adopts the following technical scheme: The antibacterial dressing composition comprises, by weight, 70-90 parts of water, 8-10 parts of polyethylene glycol, 4-6 parts of glycerin, 0.3-0.7 part of carbomer, 0.06-0.15 part of L-cysteine, 4-8 parts of chitosan quaternary ammonium salt, 0.3-0.8 part of panthenol, 0.4-0.7 part of tocopheryl acetate, 0.2-0.4 part of sodium hyaluronate, 0.1-0.3 part of chlorhexidine digluconate, 3-4 parts of polyvinylpyrrolidone, 1-5 parts of sodium alginate, 0.1-0.3 part of polysorbate, 0.6-0.9 part of luteolin, ‌ 0.1.1-0.2 part of quercetin and 0.05-0.2 part of matrine. Preferably, the antibacterial dressing composition further comprises 0.8-1.7 parts by weight of xanthan gum. Preferably, the antibac