CN-121972248-A - Microfluidic chip and microbubble generation and migration evaluation device

CN121972248ACN 121972248 ACN121972248 ACN 121972248ACN-121972248-A

Abstract

The invention belongs to the technical field of microfluidics, and discloses a microfluidic chip and a microbubble generation and migration evaluation device. The microfluidic chip includes a first layer plate and a second layer plate. The first laminate is provided with an outer phase passage, an inner phase passage, a buffer chamber, and a first communication hole. The first layer plate and the second layer plate are sequentially distributed from bottom to top along the vertical direction, and the first communication holes are communicated with the second communication holes. The micro-bubbles enter the buffer cavity and then are firstly decelerated, the gravity of the micro-bubbles is overcome, the micro-bubbles can pass through the first communication hole and the second communication hole, and finally enter the channel homogenizing model through the diversion channel, so that the flow speed of the micro-bubbles is greatly slowed down, and the migration and blocking conditions of the micro-bubbles can be carefully observed. The invention integrates the generation and migration evaluation of the micro-bubbles, has no consumption of the micro-bubbles in the middle storage process, ensures the accuracy of test results, and greatly shortens the test period.

Inventors

ZHANG FAN
ZHU XIUYU
ZOU XINYUAN
CUI XIANGLONG
HAN LU
ZHOU CHAOHUI
ZHANG QUN
ZHANG BO
GAO MING
XU YING
SHANGGUAN YANGNAN
WANG LILI

Assignees

中国石油天然气股份有限公司

Dates

Publication Date: 20260505
Application Date: 20260326

Claims (10)

1. Microfluidic chip characterized by comprising a first layer (51) and a second layer (52); The first laminate (51) is provided with an outer phase channel (511), an inner phase channel (512), a buffer cavity (513) and a first communication hole (514), wherein the outer phase channel (511) and the inner phase channel (512) are communicated with each other and then are communicated with the buffer cavity (513), the first communication hole (514) is arranged in the buffer cavity (513), an outer phase inlet (5111) of the outer phase channel (511) is used for introducing outer phase liquid, and an inner phase inlet (5121) of the inner phase channel (512) is used for introducing inner phase gas-liquid mixture; The second laminate (52) is provided with a second communication hole (521), a diversion channel (522) and a channel homogenizing model (523), and the diversion channel (522) is communicated between the second communication hole (521) and the channel homogenizing model (523); The first laminate (51) and the second laminate (52) are distributed in this order from bottom to top in the vertical direction, and the first communication hole (514) and the second communication hole (521) are communicated.
2. The microfluidic chip according to claim 1, wherein the microfluidic chip (5) further comprises an intermediate plate (53), the intermediate plate (53) being provided with a third communication hole (531); the first laminate (51), the intermediate laminate (53) and the second laminate (52) are sequentially attached from bottom to top in the vertical direction, and the first communication hole (514), the third communication hole (531) and the second communication hole (521) are sequentially communicated.
3. The microfluidic chip according to claim 2, wherein two channel homogenizing models (523) are provided, the flow dividing channel (522) comprises a first flow dividing channel (5221) and two second flow dividing channels (5222), the two second flow dividing channels (5222) are respectively in one-to-one correspondence with the two channel homogenizing models (523), the first flow dividing channel (5221) has a first inlet and two first outlets, the second flow dividing channel (5222) has a second inlet and two second outlets, the first inlet is communicated with the second communication hole (521), the two first outlets are respectively communicated with the second inlets of the two second flow dividing channels (5222), and the two second outlets of each second flow dividing channel (5222) are respectively communicated with the corresponding channel homogenizing models (523).
4. A microfluidic chip according to claim 3, wherein the channel homogenizing model (523) comprises a model cavity (5231) and a plurality of columns (5232) arranged in the model cavity (5231) and distributed in a matrix; The first sub-runner (5221), the second sub-runner (5222) and the model cavity (5231) are all arranged on the surface of the second laminate (52) facing the middle laminate (53), and the middle laminate (53) is attached to the second laminate (52) to seal the first sub-runner (5221), the second sub-runner (5222) and the model cavity (5231).
5. The microfluidic chip according to claim 4, wherein the diameters of the pillars (5232) in the grooves of the two channel homogenization models (523) are different.
6. The microfluidic chip according to any one of claims 1-5, wherein the microfluidic chip (5) further comprises a substrate (54), the first layer plate (51) being arranged on the substrate (54) in the vertical direction; The outer phase channel (511), the inner phase channel (512) and the buffer cavity (513) are all arranged on the surface of the first layer plate (51) facing the substrate (54), and the substrate (54) is attached to the first layer plate (51) to seal the outer phase channel (511), the inner phase channel (512) and the buffer cavity (513).
7. The microfluidic chip according to any one of claims 1 to 5, wherein two external phase channels (511) are provided, the two external phase channels (511) are symmetrically distributed on two sides of the internal phase channel (512), and external phase outlets of the two external phase channels (511) are in butt joint communication and are distributed in crisscross communication with the internal phase channel (512).
8. The microfluidic chip according to any one of claims 1-5, wherein the first plate (51) is further provided with a waste liquid outlet (515) in communication with the buffer chamber (513); the second deck (52) is further provided with a fluid inlet and outlet (524) communicating with the channel homogenizing model (523).
9. The microfluidic chip according to any one of claims 1-5, wherein the outer phase channel (511) and the inner phase channel (512) are each provided with a serpentine bend.
10. Microbubble generation and migration evaluation device, characterized by, including outer looks injection mechanism (1), interior looks injection mechanism (2), test bench (3), micro-mechanism (4) and claim 1-9 arbitrary micro-fluidic chip (5), micro-fluidic chip (5) with micro-mechanism (4) all set up in on test bench (3), micro-mechanism (4) are used for observing microbubble migration and shutoff condition in micro-fluidic chip (5), the delivery outlet of outer looks injection mechanism (1) with outer looks entry (5111) intercommunication is used for the input outer looks liquid, the delivery outlet of interior looks injection mechanism (2) with interior looks entry (5121) intercommunication is used for the input interior looks gas-liquid mixture.

Description

Microfluidic chip and microbubble generation and migration evaluation device Technical Field The invention relates to the technical field of microfluidics, in particular to a microfluidic chip and a microbubble generation and migration evaluation device. Background Microfluidic (microscopic visualization) technology is widely used in the biomedical, chemical synthesis, microelectronics and enhanced oil recovery technical fields. In the development process of the oil field, the development object is changed into low-permeability, strong-heterogeneity and high-temperature and high-salt oil reservoirs, the chemical flooding and gas flooding improvement three-time recovery ratio is widely applied to the oil field, and the alkali-polymer-surfactant system, the foam flooding system and the carbon dioxide flooding system have good application prospects in comprehensive aspects. However, as the heterogeneity of the oil field reservoir increases, carbon dioxide gas easily bursts along the high permeable layer, resulting in a reduction in the displacement effect, while foam liquid films are easily broken after being discharged and extruded, and when facing low permeable reservoirs, the common foam has a larger size, resulting in high injection pressure, and limited application. Compared with foam, the size of the micro-bubbles is smaller, the interface effect between the micro-bubbles and crude oil can be enhanced, the oil-water tension is reduced, the flow of the crude oil is promoted, and in addition, the thought of adjustable resistance of the micro-bubbles can be utilized for the channeling phenomenon in gas flooding, so that an oil displacement technology for low-permeability oil reservoir development is formed. At present, the micro-model chip is often presented in a two-dimensional mode, and in order to study the migration of micro-bubbles, the micro-bubbles generated by the micro-model chip are stored and then injected into the medium chip in the traditional process. The process microbubbles not only can waste part of test materials in the storage process, but also can prolong the test period, and correspond to some special test products, if the process microbubbles are improperly stored, the test products can be deteriorated, and further, the test results are deviated. Disclosure of Invention The invention aims to provide a micro-fluidic chip and a micro-bubble generation and migration evaluation device, which integrate the generation and migration evaluation of micro-bubbles into a whole, have no consumption of micro-bubbles in the middle storage process, ensure the accuracy of test results and greatly shorten the test period. To achieve the purpose, the invention adopts the following technical scheme: A microfluidic chip comprising a first layer plate and a second layer plate; The first laminate is provided with an outer phase channel, an inner phase channel, a buffer cavity and a first communication hole, wherein the outer phase channel and the inner phase channel are communicated with each other and then are communicated with the buffer cavity, the first communication hole is formed in the buffer cavity, an outer phase inlet of the outer phase channel is used for introducing outer phase liquid, and an inner phase inlet of the inner phase channel is used for introducing inner phase gas-liquid mixture; The second laminate is provided with a second communication hole, a diversion channel and a channel homogenizing model, and the diversion channel is communicated between the second communication hole and the channel homogenizing model; the first layer plate and the second layer plate are sequentially distributed from bottom to top along the vertical direction, and the first communication hole is communicated with the second communication hole. In one embodiment, the microfluidic chip further comprises an intermediate plate provided with a third communication hole; the first laminate, the middle laminate and the second laminate are sequentially attached from bottom to top along the vertical direction, and the first communication hole, the third communication hole and the second communication hole are sequentially communicated. In one embodiment, the channel homogenizing model is provided with two, the split channel comprises a first split channel and two second split channels, the two second split channels are respectively in one-to-one correspondence with the two channel homogenizing models, the first split channel is provided with a first inlet and two first outlets, the second split channel is provided with a second inlet and two second outlets, the first inlet is communicated with the second communication hole, the two first outlets are respectively communicated with the second inlets of the two second split channels, and the two second outlets of each second split channel are respectively communicated with the corresponding channel homogenizing model. In one embodiment, the channel homogenizing model com