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CN-121972250-A - Peristaltic module and cryoprecipitation preparation instrument

CN121972250ACN 121972250 ACN121972250 ACN 121972250ACN-121972250-A

Abstract

The application relates to the technical field of plasma preparation equipment, and discloses a peristaltic module which is applied to a Leng Chendian preparation instrument, wherein a frozen plasma bag and a transfer bag which are communicated through a catheter are accommodated in the cryoprecipitation preparation instrument, and the height of the frozen plasma bag is higher than that of the transfer bag. The peristaltic module comprises a peristaltic device, a driving module and a clamping mechanism. The peristaltic device is used for extruding or releasing the catheter to control the liquid to flow, the clamping mechanism is connected to the output end of the driving module and is used for executing linear motion under the driving of the driving module so as to press the catheter on the peristaltic device or release the catheter from the peristaltic device. The peristaltic pump is arranged in such a way, the active driving function of the peristaltic module and the siphon process are integrated, the equipment automation degree and the operation experience are effectively improved, and the whole process of the fluid transfer stage in the preparation process can be accurately and automatically controlled. Meanwhile, the application also discloses a cryoprecipitation preparation instrument.

Inventors

  • LI HAIMIN
  • SHI JIABIN
  • LI CHAOBO
  • LIU KUN
  • GAO XIA
  • YUAN HAO

Assignees

  • 青岛海尔生物医疗科技有限公司
  • 青岛海尔生物医疗股份有限公司

Dates

Publication Date
20260505
Application Date
20260130

Claims (11)

  1. 1. Peristaltic module, characterized in that it is applied to a cryoprecipitation preparation instrument containing a frozen plasma bag (21) and a transfer bag (22) communicating through a duct (23), and the frozen plasma bag (21) being higher in height than the transfer bag (22); The peristaltic module (50) comprises: peristaltic means (51) for squeezing or releasing said conduit (23) to control the flow of liquid; A drive module (52), and, -A gripping mechanism (53) connected to the output of the driving module (52), the gripping mechanism (53) being adapted to perform a linear movement under the driving of the driving module (52) to press the catheter (23) against the peristaltic device (51) or to release the catheter (23) from the peristaltic device (51); the driving module (52) is used for driving the clamping mechanism (53) to press the guide tube (23) so as to match the peristaltic device (51) to actively pump the liquid in the guide tube (23), and driving the clamping mechanism (53) to release the guide tube (23) so as to enable the liquid in the guide tube (23) to form siphon flow under the action of external liquid level difference.
  2. 2. Peristaltic module according to claim 1, characterized in that the gripping mechanism (53) comprises: a first push rod (531), one end of which is connected with the output end of the driving module (52); a second push rod (532), and, A push plate (533) connected to said second push rod (532) for directly contacting and pressing said guide pipe (23); wherein the first push rod (531) and the second push rod (532) are connected by a floating connection structure, so that the push plate (533) can adaptively compress the catheter (23).
  3. 3. Peristaltic module according to claim 2, characterized in that said peristaltic means (51) comprise: A drive motor (511); a peristaltic slider (512) connected to the driving motor (511) through a transmission mechanism (513) and driven by the driving motor (511) to reciprocate or rotate so as to periodically squeeze the catheter (23), and, A pump body frame (514) for supporting the drive motor (511) and the peristaltic slider (512); wherein the push plate (533) of the clamping mechanism (53) is arranged to press the catheter (23) against the working surface of the peristaltic slider (512).
  4. 4. A peristaltic module as claimed in claim 3, wherein, The transmission mechanism (513) is a synchronous belt transmission mechanism (513); The output shaft of the driving motor (511) is provided with a driving belt (515) wheel, the peristaltic sliding block (512) and the driven belt wheel (516) are coaxially arranged, and the synchronous belt is tensioned between the driving belt (515) wheel and the driven belt wheel (516); Wherein, the pushing plate (533) compresses the guide pipe (23) on the peristaltic slide block (512) under the compressing state.
  5. 5. A peristaltic module as claimed in claim 3, wherein, The pump body frame (514) and/or the push plate (533) are provided with clamping grooves corresponding to the guide pipes (23), and the clamping grooves are used for pre-positioning the guide pipes (23) before the driving module (52) acts.
  6. 6. A cryoprecipitation preparation apparatus, comprising: Peristaltic module (50) according to any one of claims 1 to 5.
  7. 7. The cryoprecipitation preparation apparatus as recited in claim 6, further comprising: A preparation module (30) for respectively containing a frozen plasma bag (21) and a transfer bag (22), the transfer bag (22) being in communication with the frozen plasma bag (21) through a conduit (23) and the transfer bag (22) being at a height lower than the frozen plasma bag (21), and, The control system is electrically connected with the preparation module (30) and the peristaltic module (50) respectively; wherein the control system is used for controlling the peristaltic module (50) to act on the conduit (23) so as to transfer the blood plasma in the frozen blood plasma bag (21) to the transfer bag (22) through the conduit (23).
  8. 8. The cryoprecipitation preparation apparatus as recited in claim 7, further comprising: -a weighing assembly (60) for obtaining the weight of the frozen plasma bag (21) and the transfer bag (22), respectively; the control system is also electrically connected to the weighing assembly (60) to control the operating state of the peristaltic module (50) according to the weight of the frozen plasma bags (21) and the transfer bags (22).
  9. 9. The cryoprecipitation preparation device according to claim 8, wherein controlling the operation state of the peristaltic module (50) according to the weight of the frozen plasma bag (21) and the transfer bag (22) comprises: If the weight increase of the transfer bag (22) is detected, the liquid in the frozen plasma bag (21) is judged to flow into the transfer bag (22), and a driving module (52) is controlled to drive a clamping mechanism (53) to release the guide tube (23).
  10. 10. The apparatus according to claim 9, wherein, After the gripping mechanism (53) releases the catheter (23), the peristaltic module (50) is controlled to stop to maintain the liquid flow by a siphon effect created by the difference in height between the frozen plasma bag (21) and the transfer bag (22).
  11. 11. The apparatus according to claim 8, wherein, And controlling the driving module (52) to drive the clamping mechanism (53) to press the guide tube (23) under the condition that the weight of the transferred plasma bag is larger than or equal to a preset weight threshold value.

Description

Peristaltic module and cryoprecipitation preparation instrument Technical Field The application relates to the technical field of plasma preparation equipment, in particular to a peristaltic module and a cryoprecipitate preparation instrument. Background In the field of blood product preparation, the preparation of cryoprecipitation is one of the key procedures, and the core of the cryoprecipitate is to separate cryoprecipitate components rich in blood coagulation factors after thawing fresh frozen plasma in a low-temperature water bath. In this process, the siphon effect is often used to achieve an efficient transfer of plasma by establishing a liquid level difference between the thawing bag and the transfer bag, so that the thawed plasma automatically flows to the transfer bag under the action of gravity and pressure difference, which is milder than continuous mechanical pumping, helping to reduce physical damage to blood components. In the related art, conventional cryoprecipitation equipment often relies on simple manual operations or discrete mechanical components to control the start and stop of siphoning. For example, an operator is required to manually clamp the pipeline into or out of the fixed clamping groove, or the pipeline is controlled to be switched on or switched off and pumped by a separate pinch valve and a peristaltic pump respectively. In the process of implementing the embodiments of the present disclosure, it is found that at least the following problems exist in the related art: In the related art, the fluid transfer module in the existing cryoprecipitation preparation instrument cannot integrate the active driving function of the peristaltic pump and the automatic pipeline control function of the siphoning process into a whole efficiently and reliably, so that the equipment automation degree is low, the operation experience is poor, and the whole process of the fluid transfer stage in the preparation process is difficult to realize accurate and automatic control. It should be noted that the information disclosed in the above background section is only for enhancing understanding of the background of the application and thus may include information that does not form the prior art that is already known to those of ordinary skill in the art. Disclosure of Invention The following presents a simplified summary in order to provide a basic understanding of some aspects of the disclosed embodiments. This summary is not an extensive overview, and is intended to neither identify key/critical elements nor delineate the scope of such embodiments, but is intended as a prelude to the more detailed description that follows. The embodiment of the disclosure provides a peristaltic module and a cryoprecipitation preparation instrument, which integrate the active driving function of the peristaltic module and a siphoning process, effectively improve the automation degree and operation experience of equipment, and can realize the whole-course accurate and automatic control of the fluid transfer stage in the preparation process. The embodiment of the disclosure provides a peristaltic module, which is applied to Leng Chendian preparation instruments, wherein frozen plasma bags and transfer bags which are communicated through a catheter are accommodated in the cryoprecipitation preparation instruments, and the height of the frozen plasma bags is higher than that of the transfer bags. The peristaltic module comprises a peristaltic device, a driving module and a clamping mechanism. The peristaltic device is used for extruding or releasing the catheter to control the liquid to flow, the clamping mechanism is connected to the output end of the driving module and is used for executing linear motion under the driving of the driving module so as to press the catheter on the peristaltic device or release the catheter from the peristaltic device. The driving module is used for driving the clamping mechanism to compress the guide pipe so as to match the peristaltic device to actively pump the liquid in the guide pipe, and driving the clamping mechanism to release the guide pipe so as to enable the liquid in the guide pipe to form siphon flow under the action of external liquid level difference. In some embodiments, the clamping mechanism includes a first push rod, a second push rod, and a push plate. One end of the first push rod is connected with the output end of the driving module, the push plate is connected with the second push rod and is used for directly contacting and pressing the guide pipe, and the first push rod is connected with the second push rod through a floating connection structure, so that the push plate can adaptively press the guide pipe. In some embodiments, the peristaltic device includes a drive motor, a peristaltic block, and a pump body frame. The peristaltic slide block is connected with the driving motor through the transmission mechanism and is driven by the driving motor to perform rec