CN-121973992-A - Integrated blister packagine machine of three dosage forms of bio-pharmaceuticals

CN121973992ACN 121973992 ACN121973992 ACN 121973992ACN-121973992-A

Abstract

The application discloses a three-dosage form integrated blister packaging machine for biopharmaceuticals, which relates to the technical field of biopharmaceutical packaging machines and comprises a machine base, a blister forming assembly, a product filling assembly and a post-processing assembly, wherein the blister forming assembly comprises a film loading roller, a plurality of groups of guide rollers, a pair of heating plates, a step-by-step forming part and a tensioning roller, the film loading roller is rotatably arranged in the machine base, the guide rollers are rotatably arranged in the machine base, the heating plates are symmetrically arranged in the machine base, the tensioning roller is rotatably arranged in the machine base and is positioned on one side of the step-by-step forming part, which is away from the heating plates, and the product filling assembly comprises a feeding wheel, a filling plate, a plurality of groups of fixing plates, a plurality of groups of guide plates, a plurality of groups of vibration feeding parts and a vacuum impurity removing part. According to the application, medicines with different specifications and dosage forms can be packaged on the same aluminum plastic plate according to actual needs, and the packaging flexibility of the blister packaging machine is improved.

Inventors

ZHANG WEIZHONG
ZHAO ZHANQIANG
ZHANG YAJUN
NIU XIAOWEI

Assignees

山西美好蕴育生物科技有限责任公司

Dates

Publication Date: 20260505
Application Date: 20260325

Claims (10)

1. A biopharmaceutical three-dosage form integrated blister packaging machine comprising: A base; The bubble cap forming assembly is arranged in the machine seat and comprises a film loading roller, a plurality of groups of guide rollers, a pair of heating plates, a step forming part and a tensioning roller; the film loading rollers are rotatably arranged in the machine base, the guide rollers are rotatably arranged in the machine base, the heating plates are symmetrically arranged in the machine base, the step-by-step forming components are arranged on one side of the heating plates, which is away from the guide rollers, and are used for preforming and positive pressure forming of plastic bubble caps, and the tensioning rollers are rotatably arranged in the machine base and are positioned on one side of the step-by-step forming components, which is away from the heating plates; the product filling assembly is fixedly arranged above the machine base and comprises a feeding wheel, a filling plate, a plurality of groups of fixing plates, a plurality of groups of guide plates, a plurality of groups of vibration feeding components and a vacuum impurity removing component; the feeding wheel is rotatably arranged on one side of the machine base, the packing plates are fixedly arranged above the machine base, a plurality of groups of fixing plates are uniformly distributed above the packing plates, a plurality of groups of guide plates are arranged corresponding to the plurality of groups of fixing plates, the guide plates are matched with the fixing plates to form a discharging channel, a plurality of groups of vibration feeding components are arranged in one-to-one correspondence with the plurality of groups of guide plates and used for feeding materials to the discharging channel, and the vacuum impurity removing components are arranged on one side of the guide plates, which is away from the feeding wheel; And the post-processing assembly is fixedly arranged on one side of the vacuum impurity removal component, which is away from the guide plate, and is used for carrying out heat sealing, batch number stamping and blanking.
2. The three-dosage form integrated blister packaging machine for biopharmaceuticals of claim 1, wherein the step-by-step forming assembly comprises a forming box, a jacking cam servo drive, a roller seat, a plurality of forming uprights, a forming middle guide plate, a water draining groove plate and a lower forming die, wherein the forming box is fixedly arranged in a machine base, the jacking cam servo drive is rotatably arranged in the forming box, and the roller seat is slidably arranged in the forming box and is positioned above the jacking cam servo drive.
3. The three-dosage form integrated blister packaging machine for biopharmaceuticals of claim 2, wherein the plurality of molding columns are fixedly arranged in the molding box, the middle molding guide plate is slidably sleeved on the outer sides of the plurality of molding columns, and the lower water trough plate and the lower molding die are sequentially and fixedly arranged above the middle molding guide plate.
4. The three-dosage form integrated blister packaging machine for biopharmaceutical production, as set forth in claim 3, wherein the step-by-step molding unit further comprises an upper die holder, an air passage die, a preforming die and a plurality of groups of preforming cylinders, wherein the upper die holder is fixedly connected with the upper ends of the plurality of molding columns, the air passage die is fixedly connected with the upper die holder at one side close to the lower molding die, the preforming die is slidingly arranged in the air passage die, a plurality of groups of preforming cylinders are fixedly arranged above the upper die holder, and the telescopic ends of the plurality of groups of preforming cylinders are fixedly connected with the preforming die.
5. The three-dosage form integrated blister packaging machine for biopharmaceuticals of claim 1, wherein the blister forming assembly further comprises a box seat, a plurality of groups of clamping cylinders and a pair of clamping rollers, the box seat is fixedly arranged in the machine base, the tensioning rollers are rotatably arranged in the box seat, the pair of clamping cylinders are fixedly arranged on the outer side of the box seat, the pair of clamping rollers are arranged on the outer side of the tensioning rollers, and the pair of clamping rollers are respectively rotatably connected with the telescopic ends of the plurality of groups of clamping cylinders.
6. The three-dosage form integrated blister packaging machine for biopharmaceuticals of claim 1, wherein the vibration feeding component comprises a vibration disc, a pair of guide grooves, a plurality of groups of blanking cover plates and a blanking sensor, the vibration disc is arranged above the guide plates, the vibration disc is internally provided with the pair of guide grooves, the pair of guide grooves are communicated with the blanking channels, the plurality of groups of blanking cover plates are fixedly arranged above the filler plates and are matched with the plurality of groups of guide plates, and the blanking sensor is fixedly arranged below the vibration disc and corresponds to the blanking channels.
7. The three-dosage form integrated blister packaging machine for biopharmaceuticals of claim 6, wherein the vibration feeding component further comprises a fixing frame, a storage vat, a feeding cylinder and a baffle plate, wherein the fixing frame is fixedly arranged above the vibration plate, the storage vat is fixedly connected with the fixing frame, the feeding cylinder is fixedly arranged below the fixing frame, the baffle plate is fixedly connected with the telescopic end of the feeding cylinder, and the baffle plate is matched with the discharge hole of the storage vat.
8. The three-dosage form integrated blister packaging machine for biopharmaceuticals of claim 1, wherein the vacuum impurity removing component comprises an impurity removing cover and an exhaust pipe, wherein the impurity removing cover is fixedly arranged above the filler plate, a filter screen is fixedly arranged at an opening at the lower side of the impurity removing cover, and the exhaust pipe is fixedly arranged above the impurity removing cover.
9. The three-agent type integrated blister packaging machine for biopharmaceuticals of claim 1, wherein the post-processing assembly comprises a dust cover, a limiting roller, a rotating frame, an anilox roller, an aluminum foil loading roller, a guiding limiting roller, a driving box seat, a stamping die and a blanking die, wherein the dust cover is fixedly arranged on one side of the machine base, the limiting roller is rotatably arranged in the dust cover, the rotating frame is rotatably arranged in the dust cover, and the rotating frame is rotatably connected with the anilox roller on one side close to the limiting roller.
10. The three-agent type integrated blister packaging machine for biopharmaceuticals of claim 9, wherein the aluminum foil loading roller is rotatably arranged in a dust cover, a plurality of groups of guiding limit rollers are rotatably arranged in the dust cover, the driving box seat is fixedly arranged in the dust cover, and the stamping die and the blanking die are respectively fixedly arranged at two ends of the driving box seat.

Description

Integrated blister packagine machine of three dosage forms of bio-pharmaceuticals Technical Field The application relates to the technical field of biopharmaceutical packaging machines, in particular to a biopharmaceutical three-dosage-form integrated blister packaging machine. Background The biopharmaceutical blister packaging machine is a packaging device for sealing medicines between transparent plastic film blisters and a bottom plate (such as aluminum foil), and the working flow of the biopharmaceutical blister packaging machine mainly comprises material heating, blister forming, product filling, heat sealing, lot number embossing, blanking and dicing and finished product conveying. The common bio-pharmaceuticals blister packaging machine in the prior art is used for packaging the same medicine, namely, the medicines with the same specification and dosage form are packaged, the medicines with different specifications and dosage forms cannot be packaged on an aluminum plastic plate according to actual demands, the packaging treatment of medicines with multiple specifications and dosage forms according to daily/times of dosage cannot be met, in addition, in the blister forming treatment, the processing is carried out in a one-time stamping forming mode, the wall thickness of the formed blister is thinner, and the forming effect is poor. Disclosure of Invention In order to solve the problem that a biopharmaceutical blister packaging machine in the prior art cannot integrate and package multi-dosage medicines on the same aluminum plastic plate according to actual demands, the application provides the biopharmaceutical three-dosage integrated blister packaging machine. The application provides a three-dosage form integrated blister packaging machine for bio-pharmaceuticals, which adopts the following technical scheme: The three-dosage-form integrated blister packaging machine comprises a machine base, a blister forming assembly, a product filling assembly and a post-processing assembly, wherein the blister forming assembly is arranged in the machine base and comprises a film loading roller, a plurality of groups of guide rollers, a pair of heating plates, a step forming part and a tensioning roller, the film loading roller is rotatably arranged in the machine base, the guide rollers are rotatably arranged in the machine base, the heating plates are symmetrically arranged in the machine base, the step forming part is arranged on one side of the heating plates, which is far away from the guide rollers, and is used for preforming and positive pressure forming of plastic blisters, the tensioning roller is rotatably arranged in the machine base and is positioned on one side, which is far away from the heating plates, of the step forming part, the product filling assembly is fixedly arranged above the machine base and comprises a feeding wheel, a filling plate, a plurality of groups of fixing plates, a plurality of groups of guide plates, a plurality of vibration feeding parts and vacuum impurity removing parts, the guide plates are fixedly arranged above the machine base, the fixing plates are uniformly distributed above the filling plate, the guide plates are arranged on one side of the machine base, the guide plates are corresponding to the fixing plates, the guide plates are arranged on one side of the guide plates, the guide plates are opposite to the fixing plates, the guide plates are arranged on one side of the guide plates, and are corresponding to the guide plates, the guide plates are arranged on one side, and are opposite to the fixing plates, and are arranged on one side, and are used for carrying out vacuum impurity removing, and pressing, and forming. By adopting the technical scheme, the plastic film is unreeled and supported by the film loading roller, and is conveyed into the step-by-step forming component for prepressing forming and positive pressure forming after being heated by the heating plate, so that a bubble cap is formed on the plastic film. And then, filling medicines into the bubble caps through the matching of the plurality of groups of vibration feeding parts and the blanking channels, and carrying out heat sealing, batch number embossing and blanking on the plastic film bubble caps by adopting a post-processing assembly. Optionally, the step-by-step shaping part includes shaping case, jacking cam servo drive, gyro wheel seat, many shaping stands, in the shaping baffle, lower basin board and lower moulded die, the shaping case is fixed to be set up in the frame, jacking cam servo drive rotates to set up in the shaping case, the gyro wheel seat slides and sets up in the shaping case. By adopting the technical scheme, the roller seat is driven to lift up in a servo driving rotation mode of the driving lifting cam. Optionally, a plurality of shaping stand is all fixed to be set up in the shaping incasement, the baffle slip cap is located the outside of a plurality of shaping stand in t