CN-121975136-A - Carboxylic acid polymer supermolecule emulsifier and preparation method and application thereof

Abstract

The invention discloses a carboxylic acid polymer supermolecular emulsifier and a preparation method and application thereof, and belongs to the technical field of supermolecular emulsifier preparation. The preparation method comprises the steps of dispersing carboxylic acid polymer and fatty acid sodium in a solvent to obtain a dispersion liquid, adding fatty acid and alcohol into the dispersion liquid, uniformly mixing to obtain a suspension, and finally drying the suspension to obtain the carboxylic acid polymer supermolecular emulsifier. The method for preparing the carboxylic acid polymer supermolecular emulsifier is simple, has low cost, and the prepared carboxylic acid polymer supermolecular emulsifier has high emulsification efficiency, low addition amount and excellent emulsion stability, and has wide application prospect in the fields of cosmetics and medicine preparation.

Inventors

• ZHANG JIAXIANG
• ZHANG YUE
• ZHANG XIN

Assignees

• 优姿康生物科技(无锡)有限公司

Dates

Publication Date

20260505

Application Date

20260204

Claims (10)

1. 1. A method for preparing a carboxylic acid polymer supermolecular emulsifier, comprising the steps of: (1) Dispersing a carboxylic acid polymer and fatty acid sodium in a solvent to obtain a dispersion liquid; (2) Adding fatty acid and alcohol into the dispersion liquid, and uniformly mixing to obtain a suspension liquid; (3) Drying the suspension to obtain carboxylic acid polymer supermolecular emulsifier powder; wherein the mass ratio of the carboxylic acid polymer to the fatty acid sodium to the fatty acid to the alcohol to the solvent is 1-30:8-25:0-10:35-91:450.
2. 2. The method of claim 1, wherein the carboxylic acid polymer in step (1) is one or two of carbomers and sodium polyglutamate, the carbomers are one or more of carbomers 980 and carbomers U20, and the sodium fatty acid is one or more of sodium stearate, sodium linoleate, sodium palmitoleate, sodium myristate, sodium oleate, sodium cocoate, sodium laurate, sodium palmitate and sodium isostearate.
3. 3. The method according to claim 1, wherein the fatty acid in the step (2) is one or more of linolenic acid, stearic acid, linoleic acid, palmitoleic acid, myristic acid, tall oil acid, oleic acid, hydrogenated coco acid, caprylic acid, capric acid, lauric acid, palmitic acid, stearic acid, isostearic acid, butyl octanoic acid, docosahexaenoic acid, eicosapentaenoic acid, and caproic acid, and the alcohol is one or more of butyl octanol, decanol, decyl tetradecanol, arachidyl alcohol, hexyl decanol, cetyl alcohol, cetylstearyl alcohol, dimethicone alcohol, myristyl alcohol, octyl dodecanol, lanosterol, lanolin alcohol, oleyl alcohol, isocetyl alcohol, isostearyl alcohol, stearyl alcohol, oleyl alcohol, lauryl alcohol, and palmitoleic alcohol.
4. 4. The method according to claim 1, wherein the dispersion in the step (1) is carried out at 25-40 ℃ and 50-200rpm for 3-12 hours, and the uniform mixing in the step (2) is carried out at 55-105 ℃ and 350-600rpm for 5-16 hours.
5. 5. The method according to claim 1, wherein the drying in step (3) is spray drying at a temperature of 160 to 200 ℃, a pressure of 0.2 to 0.5MPa, and a time of 4 to 10 hours.
6. 6. The method according to claim 1, wherein the solvent in the step (1) is water or an aqueous ethanol solution having a mass fraction of 40-60%.
7. 7. A carboxylic acid polymer supramolecular emulsifier powder prepared by the method of any one of claims 1-6.
8. 8. Use of the carboxylic acid polymer supramolecular emulsifier powder of claim 7 in the preparation of a medicament or cosmetic.
9. 9. A cosmetic, characterized in that the carboxylic acid polymer supermolecular emulsifier powder according to claim 7 is used.
10. 10. A method for improving emulsion storage stability and emulsion efficiency, characterized in that the carboxylic acid polymer supermolecular emulsifier powder of claim 7 is used.

Description

Carboxylic acid polymer supermolecule emulsifier and preparation method and application thereof Technical Field The invention relates to a carboxylic acid polymer supermolecular emulsifier, a preparation method and application thereof, and belongs to the technical field of supermolecular emulsifier preparation. Background The emulsifier is used as a key auxiliary agent capable of stabilizing an oil-water interface and reducing surface tension, and is widely applied to a plurality of fields of cosmetics, food processing, high polymer polymerization, pharmaceutical processing and the like, and the performance of the emulsifier directly determines the stability, safety and application effect of a terminal product. Currently, commonly used emulsifiers mainly include two major classes, small molecule surfactants and traditional polymer emulsifiers. The small molecular surfactant such as fatty alcohol polyoxyethylene ether, alkylbenzene sulfonate, span series and the like has the advantages of simple synthesis process and low cost, but has inherent structural defects that firstly, the hydrophilic group and the lipophilic group have weak binding force and are easy to fall off from interfaces in a medium with low polarity or nonpolar to cause the aggregation and demulsification of emulsified particles and poor stability, and secondly, the lipophilic group has limited carbon chain length (most of C18 and derivatives below), cannot form enough three-dimensional barrier, has insufficient space stabilizing effect and is difficult to adapt to the requirements of complex working conditions. In addition, in the field of cosmetics, the addition amount of the small molecular emulsifier is large, skin irritation is easy to occur, and the mild formula trend is not met. In order to overcome the defects of the small molecule emulsifier, the polymer emulsifier is gradually applied. The carboxylic acid polymer contains a large number of carboxyl groups in the molecular structure, can regulate the hydrophilic-hydrophobic balance by regulating the pH value, has certain biocompatibility and becomes a research focus. The existing polycarboxylic acid emulsifier is prepared by copolymerization of acrylic acid and acrylic ester monomers, and the HLB value is regulated by regulating the proportion of the monomers, so that the polycarboxylic acid emulsifier has certain application potential in emulsion polymerization and other scenes. However, the traditional carboxylic acid polymer emulsifier still has obvious defects that the molecular structure is a linear or simple branched structure, a dynamically adjustable interface action site is lacking, the emulsion stability is greatly influenced by environmental factors (temperature, salinity and pH value), the emulsion does not have supermolecule self-assembly characteristic, a more stable interface film structure cannot be formed through intermolecular non-covalent bond action, and the emulsion stability can be maintained in a high-requirement application scene by higher addition amount. Development of supermolecule chemistry provides a new path for emulsifier design, and supermolecule emulsifier forms a dynamic reversible supermolecule structure through self-assembly of host molecules and guest molecules, so that emulsification efficiency, stability and functional diversity can be remarkably improved. Currently, carboxylic acid polymer supermolecular emulsifiers have not been found. Therefore, in order to solve the problems of harsh reaction conditions, complex reaction, high cost and the like in the existing preparation of carboxylic acid polymer emulsifiers, development of a carboxylic acid polymer supermolecular emulsifier with simple preparation, low cost, high emulsification efficiency, low addition amount and excellent emulsion stability is needed. Disclosure of Invention In order to solve the problems, the invention provides a carboxylic acid polymer supermolecular emulsifier, and a preparation method and application thereof. The preparation method comprises the steps of dispersing a carboxylic acid polymer and fatty acid sodium in a solvent to obtain a dispersion liquid, adding fatty acid and alcohol into the dispersion liquid, uniformly mixing to obtain a suspension, and finally drying the suspension to obtain the carboxylic acid polymer supermolecular emulsifier. The method for preparing the carboxylic acid polymer supermolecular emulsifier is simple, has low cost, and the prepared carboxylic acid polymer supermolecular emulsifier has high emulsification efficiency, low addition amount and excellent emulsion stability, and has wide application prospect in the fields of cosmetics and medicine preparation. A first object of the present invention is to provide a process for preparing a carboxylic acid polymer supermolecular emulsifier comprising the steps of: (1) Dispersing a carboxylic acid polymer and fatty acid sodium in a solvent to obtain a dispersion liquid; (2) Adding fatty ac