CN-121975633-A - Ganoderma lucidum AD256, ganoderma lucidum fermented product prepared from ganoderma lucidum AD256 and application of ganoderma lucidum fermented product

CN121975633ACN 121975633 ACN121975633 ACN 121975633ACN-121975633-A

Abstract

The invention provides a ganoderma lucidum AD256 strain, a ganoderma lucidum fermented product prepared from the ganoderma lucidum AD256 strain and application of the ganoderma lucidum fermented product, and belongs to the technical field of microbial fermentation. The invention provides a ganoderma lucidum AD256, the preservation number of which is CCTCC NO: M20252522, the ganoderma lucidum AD256 is fermented in a ganoderma lucidum fermentation medium containing plant powder to prepare a ganoderma lucidum fermentation product, and the ganoderma lucidum fermentation product and the content of active substances are synchronously improved through the promotion effect of the plant powder on the ganoderma lucidum fermentation and the catalytic degradation of the ganoderma lucidum on the plant powder. The ganoderma lucidum fermented product with high active matter content has good antioxidant activity and anti-aging efficacy, and has wide market application prospect in the field of anti-aging cosmetics.

Inventors

ZHANG JINGLIANG
ZONG WENWEN
SHEN ZHAOPENG

Assignees

青岛海洋生物医药研究院股份有限公司
中国海洋大学

Dates

Publication Date: 20260505
Application Date: 20260112

Claims (10)

1. A strain of ganoderma lucidum AD256 is characterized in that ganoderma lucidum AD256 is preserved in China center for type culture collection, and the preservation number is CCTCC NO: M20252522.
2. The ganoderma lucidum AD256 according to claim 1, wherein the colony of ganoderma lucidum AD256 is white, round, dense in hyphae, and has a locked association of the mycelia.
3. The ganoderma lucidum AD256 of claim 1, wherein the ganoderma lucidum AD256 has cellulase-producing ability.
4. The ganoderma lucidum fermentation broth produced by fermenting ganoderma lucidum AD256 of claim 1, wherein the ganoderma lucidum fermentation broth is prepared by fermenting ganoderma lucidum AD256 in a ganoderma lucidum fermentation medium containing plant powder.
5. The ganoderma lucidum fermentation according to claim 4, wherein the ganoderma lucidum fermentation comprises at least one of a honeysuckle powder ganoderma lucidum fermentation, a wild chrysanthemum powder ganoderma lucidum fermentation, a sage powder ganoderma lucidum fermentation, a centella powder ganoderma lucidum fermentation and a purslane powder ganoderma lucidum fermentation.
6. The ganoderma lucidum fermentation according to claim 4, wherein the method for preparing the ganoderma lucidum fermentation comprises the following steps: (1) Inoculating the ganoderma lucidum AD256 into a liquid seed culture medium, and fermenting and culturing to obtain seed liquid; (2) Inoculating the seed solution to a ganoderma lucidum fermentation medium containing plant powder, and carrying out fermentation culture to obtain fermentation liquor, wherein the plant powder comprises at least one of honeysuckle powder, chrysanthemum indicum powder, sage powder, centella asiatica powder and purslane powder; (3) Homogenizing and homogenizing the fermentation liquor to obtain ganoderma lucidum fermentation homogenized liquor; (4) Standing the homogeneous Ganoderma fermentation liquid at room temperature, and centrifuging and filtering to obtain Ganoderma fermentation product.
7. The ganoderma lucidum fermentation product according to claim 6, wherein the particle size of the plant powder is 40-200 meshes, and the mass volume concentration of the plant powder is 5-20 g/L based on the volume of the ganoderma lucidum fermentation medium.
8. The ganoderma lucidum fermentation according to claim 7, wherein the pressure of homogenizing the fermentation broth is 80-120 MPa.
9. Use of ganoderma lucidum AD256 according to claim 1 or ganoderma lucidum fermented product according to claim 4 in the preparation of cosmetics having an anti-aging effect.
10. The use according to claim 9, wherein the cosmetic comprises at least one of a mask, an essence, an emulsion, a cream, a spray and an aqueous agent.

Description

Ganoderma lucidum AD256, ganoderma lucidum fermented product prepared from ganoderma lucidum AD256 and application of ganoderma lucidum fermented product Technical Field The invention belongs to the technical field of microorganisms, and particularly relates to ganoderma lucidum AD256, a ganoderma lucidum fermentation product prepared from the ganoderma lucidum AD256 and application of the ganoderma lucidum fermentation product. Background Ganoderma (Ganoderma lucidum) also called Mesona chinensis Ben (grass of Mesona chinensis Ben) records that Ganoderma (Ganoderma lucidum) has the effects of invigorating middle warmer and replenishing qi, improving intelligence, improving color, reducing weight after long-term eating, and prolonging life). The ganoderma lucidum contains a plurality of bioactive substances such as ganoderma lucidum polysaccharide, ganoderma lucidum triterpene and the like, plays roles of resisting oxidation, delaying aging, relieving inflammation, preserving moisture and repairing and the like in cosmetics, can also produce a large amount of biological enzymes such as cellulase, hemicellulase, glycosidase and the like in the growth process of the ganoderma lucidum, and has good biological catalytic effect on the active substances. The honeysuckle is dried flower bud or flower to be opened of honeysuckle Lonicera japonica thunder and longhairy asian tree of the genus lonicera of the family lonicera, contains a plurality of bioactive substances such as polysaccharide, phenolic acid, flavone and the like, and plays roles of antioxidation, anti-aging, relieving anti-inflammatory, barrier repair, moisturizing, antibiosis and the like in cosmetics. The wild chrysanthemum is the head-like inflorescence of perennial herb wild chrysanthemum of the asteraceae, contains a plurality of bioactive substances such as polysaccharide, flavone, volatile oil, alkaloid and the like, and plays roles of resisting bacteria, diminishing inflammation, whitening, moisturizing, relieving and repairing and the like in cosmetics. Salvia japonica is dried whole plant of Salvia japonica Thunb of Salvia of Labiatae, contains multiple bioactive substances such as polysaccharide, phenolic acid, flavone, terpenoid, etc., and has antioxidant, antiaging, antibacterial, antiinflammatory, moisturizing, and relieving effects in cosmetics. Centella asiatica is a dried whole plant of perennial herb CENTELLA ASIATICA of centella genus of Umbelliferae family, contains various bioactive substances such as triterpene, phenolic acid, flavone, etc., and has effects of repairing barrier, relieving inflammation, resisting oxidation, resisting aging, whitening, etc. Herba Portulacae is dry aerial part of Portulaca oleracea of Portulacaceae, contains multiple bioactive substances such as polysaccharide, flavone, polyphenol, alkaloid, etc., and has antioxidant, antiinflammatory, skin barrier repairing, and moisture keeping effects in cosmetics. The medicinal fungi bi-directional fermentation adopts Chinese medicinal materials with active ingredients as matrix, and converts the active ingredients of the medicinal matrix by using the medicinal fungi fermentation to generate new active ingredients and functions. The bidirectional fermentation can not only improve the content of active ingredients of the mycoplasm and the utilization rate of the active ingredients and the drug effect, but also convert the mycoplasm and the drug effect into a new active compound to form a new efficacy, can also reduce the toxic and side effects of the traditional Chinese medicinal materials and improve the taste of the traditional Chinese medicinal materials, and has the advantages of low production cost, high production efficiency, controllable production process, industrialized production and the like. Ganoderma lucidum is used as a high-quality edible and medicinal fungus, two-way fermentation of the ganoderma lucidum has been studied, but less research is conducted on liquid fermentation plant powder of the ganoderma lucidum. In addition, the solid state fermentation in the prior ganoderma lucidum bidirectional fermentation process has the problems of long production period and the like, the fermentation by adopting the traditional Chinese medicine aqueous extract has the problems of complex extraction process and the like, the bidirectional fermentation and the organic solvent extraction have the problems of loss of nutrient efficacy components such as polysaccharide and the like, the organic solvent residue and the like, and the addition of the traditional Chinese medicine powder or the aqueous extract in the fermentation process has the problems of complex fermentation process and easy pollution and the like. Therefore, development of a ganoderma lucidum strain capable of fermenting plant powder efficiently is needed, ganoderma lucidum by utilizing the strain is economical and efficient, plant powder with good efficacy in cosmetics is fermented, and the no