CN-121975662-A - Composite probiotic preparation for relieving heat stress of sow

Abstract

The invention discloses a compound probiotic preparation for relieving heat stress of sows and application thereof, and belongs to the technical field of animal feeds. The composite probiotic preparation comprises clostridium butyricum, bacillus subtilis, bacillus licheniformis and enterococcus faecalis, wherein the final concentration of each strain in the feed is 1X 10-6 CFU/g of clostridium butyricum, and the final concentration of each strain in the feed is 5X 10-6 CFU/g of clostridium subtilis, bacillus licheniformis and enterococcus faecalis. The preparation provided by the invention can effectively reduce stress hormone level and oxidative damage index in sow blood under heat stress conditions, improve the activity of antioxidant enzyme, improve feed intake and lactation performance in lactation period, and reduce backfat loss. Meanwhile, through the vertical transfer effect of sows and piglets, the intestinal morphology of offspring piglets is obviously improved, the intestinal barrier function and the antioxidation capability are enhanced, and the weaning weight and average daily gain of the piglets are improved, so that the negative influence of the heat stress on the reproductive performance of the sows and the growth of the piglets is comprehensively relieved. The preparation provided by the invention is green and safe, and has important application value.

Inventors

• CHE LONG
• XU MENGMENG
• NIU LIZHU
• HUO WENYING
• LI MENGYUN
• LIU LE
• PANG LIFENG

Assignees

• 河南牧业经济学院

Dates

Publication Date

20260505

Application Date

20260314

Claims (4)

1. 1. A compound probiotic preparation for relieving heat stress of sows is characterized by comprising clostridium butyricum, bacillus subtilis, bacillus licheniformis and enterococcus faecalis, wherein the bacterial content of the clostridium butyricum is 1 multiplied by 10 and 10 CFU/g, and the bacterial content of the bacillus subtilis, the bacillus licheniformis and the enterococcus faecalis is 1 multiplied by 10 and 11 CFU/g.
2. 2. The compound probiotic preparation according to claim 1, wherein the addition amount of clostridium butyricum in the feed is 100 mg/kg, and the addition amounts of bacillus subtilis, bacillus licheniformis and enterococcus faecalis in the feed are all 50 mg/kg.
3. 3. Use of a complex probiotic formulation according to claim 1 or 2 for the preparation of a feed for alleviating heat stress in sows.
4. 4. The use according to claim 3, wherein the final concentration of clostridium butyricum in the basal diet is 1 x 10≡6 CFU/g and the final concentrations of bacillus subtilis, bacillus licheniformis and enterococcus faecalis are all 5 x 10≡6 CFU/g after the complex probiotic preparation is added to the basal diet.

Description

Composite probiotic preparation for relieving heat stress of sow Technical Field The invention relates to the technical field of animal nutrition and feed additives, in particular to a compound probiotic preparation for relieving heat stress of sows. Background Sow, especially high-yield sow, because of its subcutaneous fat layer thickness, skin sweat gland is undeveloped, cause the body temperature to regulate the ability poor, is very vulnerable to the heat stress. The heat stress can seriously inhibit the feed intake of sows, and then cause a series of problems of insufficient lactation, excessive body condition consumption (aggravated backfat loss), reproductive performance reduction and the like. More seriously, the effects of heat stress can be transmitted to the suckling piglets by the litter vertical transmission effect. The lactation period is a key window period for the development of piglet intestinal tracts and the establishment of immune functions, and heat stress can damage the tight connection structure of piglet intestinal tracts, inhibit the development of villus, reduce the nutrient absorption capacity, induce oxidative stress and inflammatory reaction, and finally lead to diarrhea, growth retardation and death rate increase of piglets. In modern intensive cultivation, the heat stress problem of sows is particularly remarkable due to the high-temperature and high-humidity environment in summer, and huge economic loss is caused. Currently, common strategies for alleviating heat stress include physical cooling (e.g., wet curtains, fans), nutritional regulation (e.g., adjustment of daily ration energy concentration, addition of electrolytes), and the use of functional additives. Among them, probiotics are receiving attention as a green and safe feed additive because of their various functions of regulating intestinal flora, enhancing intestinal barrier, synthesizing nutrients and antioxidant substances. In the prior art, researches report the application of single or composite probiotics in relieving heat stress of animals such as broiler chickens, cows and the like. For example, some patent documents disclose preparations containing bacillus or lactobacillus for improving the heat stress resistance of livestock and poultry. However, there are significant differences in the physiological state, reproductive cycle, and heat stress response mechanisms of sows from broiler chickens, cows, etc. Aiming at a special group of sows, particularly under the condition of heat stress, how to simultaneously protect the health of the sows and ensure the growth and development of offspring piglets through nutritional intervention is a key problem which is not solved systematically. Most of the existing probiotics application schemes lack in-depth elucidation of special strain combinations, accurate proportioning and action mechanisms aiming at heat stress of sows, so that the effect is limited or unstable. Therefore, the special compound probiotic preparation capable of effectively relieving heat stress of sows and improving comprehensive production performance of sows and piglets is developed, and has important practical significance and application prospect. Disclosure of Invention The invention aims to solve the technical problem of providing a compound probiotic preparation for relieving heat stress of sows. The preparation is subjected to screening of specific strains and scientific compatibility, and aims to negatively influence a sow and piglet system from multi-dimensional and multi-target comprehensive dry preheating stress. In order to achieve the above purpose, the technical scheme adopted by the invention is as follows: A compound probiotic preparation for relieving heat stress of sows comprises clostridium butyricum, bacillus subtilis, bacillus licheniformis and enterococcus faecalis, wherein the bacterial content of the clostridium butyricum is 1 multiplied by 10 and 10 CFU/g, and the bacterial content of the bacillus subtilis, the bacillus licheniformis and the enterococcus faecalis is 1 multiplied by 10 and 11 CFU/g. The addition amount of clostridium butyricum in the feed is 100 mg/kg, and the addition amounts of bacillus subtilis, bacillus licheniformis and enterococcus faecalis in the feed are 50 mg/kg. The application of the composite probiotic preparation in preparing feed for relieving heat stress of sows. After the composite probiotic preparation is added into basic diet, the final concentration of clostridium butyricum in the basic diet is 1 multiplied by 10 and is 6 CFU/g, and the final concentrations of bacillus subtilis, bacillus licheniformis and enterococcus faecalis are all 5 multiplied by 10 and are 6 CFU/g. The composite probiotic preparation of the invention has the following uses: Is used for reducing the level of stress hormone (such as adrenocorticotropic hormone) and the content of oxidative damage products (such as malondialdehyde, MDA) in sow blood under heat stress co