CN-121977901-A - Pathological section machine based on air cushion is supplementary

Abstract

The invention discloses a pathological microtome based on air cushion assistance, relates to the technical field of microtomes, and aims to solve the problem that a cut slice is easy to curl when an ultrathin sample is cut. The technical scheme is that the device comprises a frame, a clamping device, a slicing device and an air cushion anti-curling device, wherein the clamping device is arranged on the frame and comprises a sample frame support, a negative pressure cavity is formed in the sample frame support, a plurality of through holes communicated with the negative pressure cavity are formed in the surface of the sample frame support, a negative pressure generator is communicated with the negative pressure cavity and used for generating and maintaining continuous negative pressure air flow, the slicing device comprises a knife rest and a knife blade, and the air cushion anti-curling device is arranged on the rear side of a cutting edge of the knife blade and comprises an air cavity and a nozzle. According to the invention, through the uniform and stable laminar air cushion generated by the flow stabilizing mechanism and the flow guide lip, a lifting force can be applied to the slices, so that the cut pathological slices can be smoothly separated from the sample, the just-cut tissue slices can be uniformly supported, and the success rate and the flatness rate of the slices are improved.

Inventors

• Li tiannv
• MA YONGGANG
• LV XIAOHANG
• Que Jinlian
• TAO YONGLING
• CHEN YUWEI
• Hong Fanglin
• WANG QIANCHEN
• ZHANG YE

Assignees

• 金华市科欣医疗科技有限公司

Dates

Publication Date

20260505

Application Date

20260129

Claims (8)

1. 1. A pathological microtome based on air cushion assist, comprising: A frame; The clamping device is arranged on the rack and comprises a sample rack support, a negative pressure cavity is formed in the sample rack support, a plurality of through holes communicated with the negative pressure cavity are formed in the surface of the sample rack support, a negative pressure generator is communicated with the negative pressure cavity and used for generating and maintaining continuous negative pressure air flow, the sample rack support is made of a heat conducting material, a semiconductor refrigerating sheet is integrated in the sample rack support and used for controlling the temperature of a sample, the through holes in the surface of the sample rack support are unevenly distributed, and the distribution density of the through holes in the center of the sample rack support is lower than that of the edge area; A slicing device comprising a blade holder and a blade; The air cushion anti-curling device is arranged at the rear side of the cutting edge of the blade and comprises an air cavity and a nozzle, wherein the nozzle is strip-shaped, the seam width of the nozzle is consistent and is 0.05-0.15mm so as to ensure uniform air outlet along the length direction of the whole cutting edge, the air cavity is communicated with an air inlet of the nozzle, the air outlet direction of the nozzle is parallel to the blade surface of the blade, a flow stabilizing mechanism for converting the air flow of the air inlet into stable static pressure flow is arranged in the air cavity, and the flow stabilizing mechanism comprises a pressure stabilizing cavity and a flow equalizing plate; the pressure stabilizing cavity is located in the air cavity and is arranged on one side of the air inlet close to the nozzle, the cross section area of the pressure stabilizing cavity is larger than that of the air outlet of the nozzle, a plurality of meshes are formed in the flow equalizing plate, and the flow equalizing plate is fixedly connected in the pressure stabilizing cavity.
2. 2. The air cushion-assisted pathology slicer of claim 1, wherein the clamping device further comprises clamping plates arranged on two sides of the sample rack support, and the clamping plates are slidably connected to the surface of the sample rack support through bolts.
3. 3. The air cushion-assisted pathological microtome of claim 1, wherein the frame is provided with a constant-temperature water bath, and a feed inlet of the constant-temperature water bath faces one side of the blade.
4. 4. The air cushion-assisted pathological microtome according to claim 1, further comprising a guide lip disposed on upper and lower sides of the nozzle near the air outlet thereof, wherein the guide lip has an inner surface roughness Ra value of not more than 0.8 μm and a smooth tapered profile for smoothly accelerating the rectified airflow toward the air outlet of the nozzle.
5. 5. The air cushion-assisted pathological microtome according to claim 1, wherein at least two flow equalizing plates which are arranged in parallel are arranged in the pressure stabilizing cavity, and mesh apertures of the flow equalizing plates are sequentially reduced along the air flow direction.
6. 6. The air cushion-assisted pathological microtome according to claim 5, wherein the mesh holes of the flow equalization plate are conical holes, and the aperture of the air inlet end is larger than that of the air outlet end.
7. 7. The air cushion-assisted pathological microtome according to claim 1, wherein the negative pressure generator comprises a vacuum pump, a negative pressure regulating valve and a pressure sensor, the pressure sensor is used for monitoring the pressure value in the negative pressure cavity in real time, and an air suction port of the vacuum pump is connected below the sample holder.
8. 8. The air cushion-assisted pathological microtome of claim 4, wherein the guide lip is made of stainless steel or hard aluminum oxide alloy material.

Description

Pathological section machine based on air cushion is supplementary Technical Field The invention relates to the technical field of slicing machines, in particular to a pathological slicing machine based on air cushion assistance. Background The pathological section technology is a vital link in histology, pathological diagnosis and research, and the quality of the pathological section technology directly influences the accuracy of subsequent observation and diagnosis. Paraffin-embedded tissue sections are one of the most common techniques. Traditional pathological section machine is mainly through mechanical sampling, the mode that the blade cut makes the tissue piece thin slice section. However, when an ultrathin sample needs to be cut, due to the physical characteristics of paraffin and friction between a slicing knife and a tissue block, the cut thin sheet is extremely easy to curl, fold and even break, the curling phenomenon affects the integrity of the slice, an operator needs to spend a great deal of time and effort to manually flatten the slice by using a writing brush or a brush, the efficiency is low, and the slice is extremely easy to damage due to improper operation. There is therefore a need to propose a new solution to this problem. Disclosure of Invention Aiming at the defects in the prior art, the invention aims to provide a pathological section machine based on air cushion assistance, which has the advantage of improving the success rate of samples. The technical aim of the invention is achieved by the following technical scheme that the pathological section machine based on air cushion assistance comprises: A frame; The clamping device is arranged on the rack and comprises a sample rack support, a negative pressure cavity is formed in the sample rack support, a plurality of through holes communicated with the negative pressure cavity are formed in the surface of the sample rack support, a negative pressure generator is communicated with the negative pressure cavity and used for generating and maintaining continuous negative pressure air flow, the sample rack support is made of a heat conducting material, a semiconductor refrigerating sheet is integrated in the sample rack support and used for controlling the temperature of a sample, the through holes in the surface of the sample rack support are unevenly distributed, and the distribution density of the through holes in the center of the sample rack support is lower than that of the edge area; A slicing device comprising a blade holder and a blade; The air cushion anti-curling device is arranged at the rear side of the cutting edge of the blade and comprises an air cavity and a nozzle, wherein the nozzle is strip-shaped, the seam width of the nozzle is consistent and is 0.05-0.15mm so as to ensure uniform air outlet along the length direction of the whole cutting edge, the air cavity is communicated with an air inlet of the nozzle, the air outlet direction of the nozzle is parallel to the blade surface of the blade, a flow stabilizing mechanism for converting the air flow of the air inlet into stable static pressure flow is arranged in the air cavity, and the flow stabilizing mechanism comprises a pressure stabilizing cavity and a flow equalizing plate; the pressure stabilizing cavity is located in the air cavity and is arranged on one side of the air inlet close to the nozzle, the cross section area of the pressure stabilizing cavity is larger than that of the air outlet of the nozzle, a plurality of meshes are formed in the flow equalizing plate, and the flow equalizing plate is fixedly connected in the pressure stabilizing cavity. The clamping device further comprises clamping plates arranged on two sides of the sample rack support, and the clamping plates are connected to the surface of the sample rack support in a sliding mode through bolts. The invention is further characterized in that the frame is provided with a constant-temperature water bath box, and a feed inlet of the constant-temperature water bath box faces one side of the blade. The invention is further provided with a diversion lip, wherein the diversion lip is arranged on the upper side and the lower side of the nozzle close to the air outlet of the nozzle, the roughness Ra value of the inner surface of the diversion lip is not more than 0.8 micron, and the contour of the diversion lip is a smooth tapered curve for guiding the rectified airflow to the air outlet of the nozzle stably and rapidly. The invention is further characterized in that at least two flow equalizing plates which are arranged in parallel are arranged in the pressure stabilizing cavity, and the mesh aperture of each flow equalizing plate is sequentially reduced along the air flow direction. The invention is further provided that the mesh holes on the flow equalizing plate are conical holes, and the aperture of the air inlet end is larger than that of the air outlet end. The invention further provides that